PT3986869T - Processo para a síntese de lofexidina - Google Patents

Processo para a síntese de lofexidina

Info

Publication number
PT3986869T
PT3986869T PT207365842T PT20736584T PT3986869T PT 3986869 T PT3986869 T PT 3986869T PT 207365842 T PT207365842 T PT 207365842T PT 20736584 T PT20736584 T PT 20736584T PT 3986869 T PT3986869 T PT 3986869T
Authority
PT
Portugal
Prior art keywords
lofexidine
synthesis
Prior art date
Application number
PT207365842T
Other languages
English (en)
Original Assignee
Procos Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Procos Spa filed Critical Procos Spa
Publication of PT3986869T publication Critical patent/PT3986869T/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/04—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D233/20—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D233/22—Radicals substituted by oxygen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Saccharide Compounds (AREA)
PT207365842T 2019-06-21 2020-06-19 Processo para a síntese de lofexidina PT3986869T (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT102019000009777A IT201900009777A1 (it) 2019-06-21 2019-06-21 Processo per la sintesi di lofexidina

Publications (1)

Publication Number Publication Date
PT3986869T true PT3986869T (pt) 2024-08-29

Family

ID=68138735

Family Applications (1)

Application Number Title Priority Date Filing Date
PT207365842T PT3986869T (pt) 2019-06-21 2020-06-19 Processo para a síntese de lofexidina

Country Status (6)

Country Link
US (1) US11459303B2 (pt)
EP (2) EP3986869B1 (pt)
ES (1) ES2986690T3 (pt)
IT (1) IT201900009777A1 (pt)
PT (1) PT3986869T (pt)
WO (1) WO2020254580A1 (pt)

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3966757A (en) 1967-02-23 1976-06-29 A. Nattermann & Cie Gmbh Imidazoline derivatives and processes for the production thereof
DE3149009A1 (de) * 1981-12-10 1983-06-23 A. Nattermann & Cie GmbH, 5000 Köln (-)-2-(1-(2,6-dichlorphenoxy)-ethyl)-1,3-diazacyclopent-2-en, dessen herstellung und seine verwendung in pharmazeutischen praeparaten
DE3149010A1 (de) 1981-12-10 1983-07-07 A. Nattermann & Cie GmbH, 5000 Köln (+)-2-(1-(2,6-dichlorphenoxy)-ethyl)-1,3- diazacyclopent-2-en, dessen herstellung und seine verwendung in pharamazeutischen praeparaten
ITTO20070479A1 (it) 2007-07-02 2009-01-03 Ceva Vetem S P A Composizione veterinaria iniettabile ad attivita' anti-prolattinica
CN101687812A (zh) 2007-07-02 2010-03-31 弗·哈夫曼-拉罗切有限公司 对痕量胺相关受体(taar)具有良好亲和性的2-咪唑啉化合物
JP2011530504A (ja) * 2008-08-08 2011-12-22 アジーン リミテッド ライアビリティー カンパニー Ｃｎｓ疾患及び病理の治療に用いるロフェキシジンエナンチオマー、並びにそのキラル合成法

Also Published As

Publication number Publication date
EP4071139A1 (en) 2022-10-12
IT201900009777A1 (it) 2020-12-21
ES2986690T3 (es) 2024-11-12
US20220204455A1 (en) 2022-06-30
EP3986869B1 (en) 2024-07-24
EP3986869A1 (en) 2022-04-27
WO2020254580A1 (en) 2020-12-24
US11459303B2 (en) 2022-10-04

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