PT773991E - Calpaina activa expressa por baculovirus - Google Patents

Calpaina activa expressa por baculovirus

Info

Publication number
PT773991E
PT773991E PT95926185T PT95926185T PT773991E PT 773991 E PT773991 E PT 773991E PT 95926185 T PT95926185 T PT 95926185T PT 95926185 T PT95926185 T PT 95926185T PT 773991 E PT773991 E PT 773991E
Authority
PT
Portugal
Prior art keywords
acapple
baculovirus
expressed
recombinant
mammalian
Prior art date
Application number
PT95926185T
Other languages
English (en)
Inventor
Sheryl L Meyer
Richard W Scott
Robert Siman
Original Assignee
Cephalon Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cephalon Inc filed Critical Cephalon Inc
Publication of PT773991E publication Critical patent/PT773991E/pt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • C12N9/48Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6472Cysteine endopeptidases (3.4.22)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2799/00Uses of viruses
    • C12N2799/02Uses of viruses as vector
    • C12N2799/021Uses of viruses as vector for the expression of a heterologous nucleic acid
    • C12N2799/026Uses of viruses as vector for the expression of a heterologous nucleic acid where the vector is derived from a baculovirus

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
PT95926185T 1994-07-15 1995-07-06 Calpaina activa expressa por baculovirus PT773991E (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US27568394A 1994-07-15 1994-07-15

Publications (1)

Publication Number Publication Date
PT773991E true PT773991E (pt) 2004-10-29

Family

ID=23053385

Family Applications (1)

Application Number Title Priority Date Filing Date
PT95926185T PT773991E (pt) 1994-07-15 1995-07-06 Calpaina activa expressa por baculovirus

Country Status (11)

Country Link
US (2) US6057143A (pt)
EP (1) EP0773991B1 (pt)
JP (1) JP4429385B2 (pt)
AT (1) ATE268816T1 (pt)
AU (1) AU3003395A (pt)
CA (1) CA2194763A1 (pt)
DE (1) DE69533135T2 (pt)
DK (1) DK0773991T3 (pt)
ES (1) ES2222465T3 (pt)
PT (1) PT773991E (pt)
WO (1) WO1996002634A1 (pt)

Families Citing this family (108)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL129909A0 (en) * 1996-12-04 2000-02-29 Basf Ag Novel calpaines their production and use thereof
DE19737105A1 (de) * 1997-08-26 1999-03-04 Basf Ag Neue gewebsspezifische Calpaine, ihre Herstellung und Verwendung
US6570003B1 (en) * 2001-01-09 2003-05-27 Lexion Genetics Incorporated Human 7TM proteins and polynucleotides encoding the same
US20050153323A1 (en) * 2000-07-28 2005-07-14 Yi Hu Novel human proteases and polynucleotides encoding the same
US20020165376A1 (en) * 1999-12-22 2002-11-07 Walke D. Wade Novel human proteases and polynucleotides encoding the same
US6448388B1 (en) 2000-08-16 2002-09-10 Lexicon Genetics Incorporated Human proteases and polynucleotides encoding the same
WO2001016336A1 (en) 1999-09-02 2001-03-08 Lexicon Genetics Incorporated Human calcium dependent proteases and polynucleotides encoding the same
US20080003673A1 (en) * 1999-09-02 2008-01-03 Alejandro Abuin Novel human proteases and polynucleotides encoding the same
US20030050464A1 (en) * 2000-07-28 2003-03-13 Yi Hu Novel human proteases and polynucleotides encoding the same
WO2001021773A2 (en) 1999-09-24 2001-03-29 Lexicon Genetics Incorporated Human endothelin converting enzyme-like proteins and polynucleotides encoding the same
US6790660B1 (en) 2001-09-18 2004-09-14 Lexicon Genetics Incorporated Human kielin-like proteins and polynucleotides encoding the same
US6867291B1 (en) * 2000-09-15 2005-03-15 Lexicon Genetics Incorporated Human hemicentin proteins and polynucleotides encoding the same
US6716616B1 (en) 1999-09-28 2004-04-06 Lexicon Genetics Incorporated Human kinase proteins and polynucleotides encoding the same
US6541252B1 (en) 2000-05-19 2003-04-01 Lexicon Genetics Incorporated Human kinases and polynucleotides encoding the same
US6797510B1 (en) * 2001-05-24 2004-09-28 Lexicon Genetics Incorporated Human kinases and polynucleotides encoding the same
US20080050809A1 (en) * 1999-09-28 2008-02-28 Alejandro Abuin Novel human kinases and polynucleotides encoding the same
US6586230B1 (en) 2000-10-27 2003-07-01 Lexicon Genetics Incorporated Human kinase and polynucleotides encoding the same
US6841377B1 (en) * 2001-06-13 2005-01-11 Lexicon Genetics Incorporated Human kinase and polynucleotides encoding the same
US6511840B1 (en) 2000-06-15 2003-01-28 Lexicon Genetics Incorporated Human kinase proteins and polynucleotides encoding the same
US6759527B2 (en) 2001-03-20 2004-07-06 Lexicon Genetics Incorporated Human kinase and polynucleotides encoding the same
CA2385883A1 (en) * 1999-09-29 2001-04-05 Lexicon Genetics Incorporated Human carboxypeptidases and polynucleotides encoding the same
US20080213878A1 (en) * 1999-10-19 2008-09-04 Gregory Donoho Novel human membrane proteins and polynucleotides encoding the same
US6815538B2 (en) 2000-03-20 2004-11-09 Lexicon Genetics Incorporated Human secreted proteins and polynucleotides encoding the same
US6743907B1 (en) 1999-10-19 2004-06-01 Lexicon Genetics Incorporated Human proteins and polynucleotides encoding the same
EP1244698A2 (en) 1999-11-02 2002-10-02 Lexicon Genetics Incorporated Novel human transporter proteins and polynucleotides encoding the same
AU783485B2 (en) * 1999-11-10 2005-11-03 Lexicon Pharmaceuticals, Inc. Human atpase proteins and polynucleotides encoding the same
EP1242588A2 (en) 1999-11-12 2002-09-25 Lexicon Genetics Incorporated Human proteins with homology to carboxypeptidases and polynucleotides encoding the same
AU785082B2 (en) 1999-12-07 2006-09-14 Lexicon Pharmaceuticals, Inc. Novel human kinase proteins and polynucleotides encoding the same
AU784486B2 (en) 1999-12-09 2006-04-13 Lexicon Genetics Incorporated Novel human proteases and polynucleotides encoding the same
US6692947B2 (en) * 1999-12-13 2004-02-17 Lexicon Genetics Incorporated Human transferase proteins and polynucleotides encoding the same
CA2397783A1 (en) * 2000-01-18 2001-07-26 Lexicon Genetics Incorporated Human gaba receptor proteins and polynucleotides encoding the same
CA2397789C (en) * 2000-01-18 2010-10-19 Lexicon Genetics Incorporated Novel human kinase protein and polynucleotides encoding the same
EP1250433A1 (en) * 2000-01-28 2002-10-23 Lexicon Genetics Incorporated Human membrane proteins and polynucleotides encoding the same
EP1301600A2 (en) * 2000-01-28 2003-04-16 Lexicon Genetics Incorporated Human enzymes and polynucleotides encoding the same
AU3690801A (en) 2000-02-11 2001-08-20 Lexicon Genetics Incorporated Human proteases and polynucleotides encoding the same
AU2001238503A1 (en) * 2000-02-17 2001-08-27 Lexicon Genetics Incorporated Novel human thrombospondin repeat proteins and polynucleotides encoding the same
US6531309B1 (en) 2000-02-29 2003-03-11 Lexicon Genetics Incorporated Human transporter proteins and polynucleotides encoding the same
WO2001066744A2 (en) * 2000-03-06 2001-09-13 Lexicon Genetics Incorporated Human transporter proteins and polynucleotides encoding the same
EP1263967A2 (en) 2000-03-10 2002-12-11 Lexicon Genetics Incorporated Human g-coupled protein receptor kinases and polynucleotides encoding the same
CA2404896A1 (en) * 2000-04-03 2001-10-11 Lexicon Genetics Incorporated Human ion channel protein and polynucleotides encoding the same
JP2004511205A (ja) 2000-04-25 2004-04-15 レキシコン・ジェネティクス・インコーポレーテッド 新規ヒトキナーゼプロテインおよびそれをコードするポリヌクレオチド
JP2003533205A (ja) * 2000-05-12 2003-11-11 レキシコン・ジェネティクス・インコーポレーテッド 新規ヒトリポカリン相同体およびそれをコードするポリヌクレオチド
WO2001088133A2 (en) * 2000-05-18 2001-11-22 Lexicon Genetics Incorporated Human semaphorin homologs and polynucleotides encoding the same
AU2001274923A1 (en) * 2000-05-23 2001-12-03 Lexicon Genetics Incorporated Novel human thrombospondin-like proteins and polynucleotides encoding the same
US6703495B2 (en) * 2000-06-07 2004-03-09 Lexicon Genetics Incorporated Polynucleotides encoding human transporter protein
US6465632B1 (en) 2000-06-09 2002-10-15 Lexicon Genetics Incorporated Human phosphatases and polynucleotides encoding the same
AU7151601A (en) * 2000-06-27 2002-01-08 Lexicon Genetics Inc Novel human gaba receptors and polynucleotides encoding the same
CA2416691A1 (en) * 2000-07-21 2002-01-31 Incyte Genomics, Inc. Proteases
US6887685B1 (en) * 2000-07-25 2005-05-03 Lexicon Genetics Incorporated Human thymosin protein and polynucleotides encoding the same
US20020076780A1 (en) * 2000-08-16 2002-06-20 Turner C. Alexander Novel human ion channel proteins and polynucleotides encoding the same
ATE334208T1 (de) * 2000-08-22 2006-08-15 Lexicon Genetics Inc Menschliche proteasen und für diese kodierende polynukleotide
AU2001285326A1 (en) * 2000-08-31 2002-03-13 Lexicon Genetics Incorporated Human kinase proteins and polynucleotides encoding the same
WO2002020753A2 (en) * 2000-09-01 2002-03-14 Lexicon Genetics Incorporated Human gaba transporter protein and polynucleotides encoding the same
CA2423942A1 (en) * 2000-09-27 2002-04-04 Lexicon Genetics Incorporated Human ion-exchanger proteins and polynucleotides encoding the same
US6777232B1 (en) 2000-10-02 2004-08-17 Lexicon Genetics Incorporated Human membrane proteins and polynucleotides encoding the same
AU2002213183A1 (en) 2000-10-12 2002-04-22 Lexicon Genetics Incorporated Human kinases and polynucleotides encoding the same
US7001763B1 (en) 2000-10-17 2006-02-21 Lexicon Genetics Incorporated Human semaphorin proteins and polynucleotides encoding the same
AU3087502A (en) * 2000-11-01 2002-05-15 Lexicon Genetics Inc Novel human proteases and polynucleotides encoding the same
CA2429519A1 (en) * 2000-11-15 2002-06-27 Lexicon Genetics Incorporated Novel human secreted proteins and polynucleotides encoding the same
WO2002042438A2 (en) 2000-11-20 2002-05-30 Lexicon Genetics Incorporated Human kinases and polynucleotides encoding the same
JP2004517622A (ja) * 2000-12-11 2004-06-17 レキシコン・ジェネティクス・インコーポレーテッド 新規ヒトキナーゼ及び該キナーゼをコードするポリヌクレオチド
CA2431210A1 (en) 2000-12-12 2002-06-20 Lexicon Genetics Incorporated Novel human kinases and uses thereof
US6583269B1 (en) * 2000-12-18 2003-06-24 Lexicon Genetics Incorporated Human protease inhibitor and polynucleotides encoding the same
US6852844B1 (en) 2000-12-20 2005-02-08 Lexicon Genetics Incorporated Human protocadherin proteins and polynucleotides encoding the same
AU2002227377A1 (en) * 2000-12-20 2002-07-01 Lexicon Pharmaceuticals, Inc. Human ion channel protein and polynucleotides encoding the same
WO2002059325A2 (en) * 2000-12-27 2002-08-01 Lexicon Genetics Incorporated Human kinases and polynucleotides encoding the same
WO2002068626A2 (en) * 2000-12-28 2002-09-06 Lexicon Genetics Incorporated Novel human ion channel-related proteins and polynucleotides encoding the same
US20020115844A1 (en) * 2001-01-05 2002-08-22 Yu Xuanchuan Sean Novel human lipase and polynucleotides encoding the same
EP1407029A2 (en) * 2001-01-23 2004-04-14 Lexicon Genetics Incorporated Novel human kinases and polynucleotides encoding the same
EP1356059A1 (en) * 2001-01-24 2003-10-29 Lexicon Genetics Incorporated Human lipase and polynucleotides encoding the same
WO2002063002A2 (en) * 2001-02-02 2002-08-15 Lexicon Genetics Incorporated Novel human transporter protein and polynucleotides encoding the same
WO2002066624A2 (en) * 2001-02-20 2002-08-29 Lexicon Genetics Incorporated Novel human protease and polynucleotides encoding the same
JP3929250B2 (ja) * 2001-03-08 2007-06-13 株式会社ルネサステクノロジ 半導体装置
JP2004535781A (ja) * 2001-03-12 2004-12-02 レキシコン・ジェネティクス・インコーポレーテッド 新規ヒトefgファミリータンパクおよびそれをコードするポリヌクレオチド
WO2002072603A2 (en) * 2001-03-12 2002-09-19 Lexicon Genetics Incorporated Novel human dectin proteins and polynucleotides encoding the same
US20020164627A1 (en) * 2001-03-12 2002-11-07 Wilganowski Nathaniel L. Novel human transporter proteins and polynucleotides encoding the same
US6994995B1 (en) * 2001-03-16 2006-02-07 Lexicon Genetics Incorporated Human synaptotagmin and polynucleotides encoding the same
EP1383880A1 (en) * 2001-04-06 2004-01-28 Lexicon Genetics Incorporated Novel human kinase and polynucleotides encoding the same
CA2443516A1 (en) * 2001-04-06 2002-10-17 Lexicon Genetics Incorporated Novel human kinases and polynucleotides encoding the same
US6644173B2 (en) * 2001-04-11 2003-11-11 Keuring, Incorporated Beverage filter cartridge holder
WO2002083706A1 (en) 2001-04-16 2002-10-24 Lexicon Genetics Incorporated Nucleic acid encoding a human adenylosuccinate synthetase
AU2002259011A1 (en) * 2001-04-30 2002-11-11 Lexicon Genetics Incorporated Novel human nuclear transporters and polynucleotides encoding the same
JP2004537986A (ja) * 2001-05-09 2004-12-24 レキシコン・ジェネティクス・インコーポレーテッド 新規キナーゼおよびそれをコードするポリヌクレオチド
US20020193585A1 (en) * 2001-05-25 2002-12-19 Walke D. Wade Novel human transporter proteins and polynucleotides encoding the same
JP2005500829A (ja) 2001-05-29 2005-01-13 レキシコン・ジェネティクス・インコーポレーテッド 新規ヒト水酸化酵素及び該酵素をコードするポリヌクレオチド
EP1406645A4 (en) * 2001-06-14 2005-02-16 Lexicon Genetics Inc NEW HUMANTRANSPORTER PROTEINS AND THESE CODING POLYNUCLEOTIDE
WO2003004609A2 (en) * 2001-07-03 2003-01-16 Lexicon Genetics Incorporated Novel human kielin-like proteins and polynucleotides encoding the same
EP1425382A4 (en) * 2001-08-14 2004-10-06 Lexicon Genetics Inc NEW HUMAN COLLAGEN PROTEINS AND THESE CODING POLYNUCLEOTIDS
FR2842824B1 (fr) * 2002-07-24 2004-11-12 Centre Nat Rech Scient Expression de recepteurs a 7 domaines transmembranaires en systeme baculovirus/cellules d'insectes
JP3447009B1 (ja) * 2002-10-29 2003-09-16 實 平垣 構築物用構成体およびその製造方法
US7312079B1 (en) 2005-10-06 2007-12-25 Lexicon Pharmaceuticals, Inc. Variants of FAM3C
GB0605761D0 (en) 2006-03-22 2006-05-03 Imp Innovations Ltd Anti-inflammatory proteins and improved vaccines
EP2271772B1 (en) * 2008-03-11 2014-07-16 Sequenom, Inc. Nucleic acid-based tests for prenatal gender determination
JP5781436B2 (ja) * 2008-08-11 2015-09-24 バンヤン・バイオマーカーズ・インコーポレーテッド 神経学的状態のバイオマーカー検出方法およびアッセイ
US12601749B2 (en) 2008-08-11 2026-04-14 Banyan Biomarkers, Inc. Biomarker detection process and assay of neurological condition
US8476013B2 (en) 2008-09-16 2013-07-02 Sequenom, Inc. Processes and compositions for methylation-based acid enrichment of fetal nucleic acid from a maternal sample useful for non-invasive prenatal diagnoses
US8962247B2 (en) 2008-09-16 2015-02-24 Sequenom, Inc. Processes and compositions for methylation-based enrichment of fetal nucleic acid from a maternal sample useful for non invasive prenatal diagnoses
ES2577017T3 (es) 2009-12-22 2016-07-12 Sequenom, Inc. Procedimientos y kits para identificar la aneuploidia
EP2820129A1 (en) 2012-03-02 2015-01-07 Sequenom, Inc. Methods and processes for non-invasive assessment of genetic variations
US10504613B2 (en) 2012-12-20 2019-12-10 Sequenom, Inc. Methods and processes for non-invasive assessment of genetic variations
US9920361B2 (en) 2012-05-21 2018-03-20 Sequenom, Inc. Methods and compositions for analyzing nucleic acid
US20140093873A1 (en) 2012-07-13 2014-04-03 Sequenom, Inc. Processes and compositions for methylation-based enrichment of fetal nucleic acid from a maternal sample useful for non-invasive prenatal diagnoses
US11060145B2 (en) 2013-03-13 2021-07-13 Sequenom, Inc. Methods and compositions for identifying presence or absence of hypermethylation or hypomethylation locus
JP6235815B2 (ja) * 2013-07-12 2017-11-22 公益財団法人東京都医学総合研究所 組換えヒトμ−カルパインの調製方法
EP3736344A1 (en) 2014-03-13 2020-11-11 Sequenom, Inc. Methods and processes for non-invasive assessment of genetic variations
US11981943B2 (en) 2016-10-11 2024-05-14 University Of Iowa Research Foundation Methods and composition for detecting CAPN5
US11078298B2 (en) 2016-10-28 2021-08-03 Banyan Biomarkers, Inc. Antibodies to ubiquitin C-terminal hydrolase L1 (UCH-L1) and glial fibrillary acidic protein (GFAP) and related methods
US11581082B2 (en) * 2020-05-15 2023-02-14 Omniscient Neurotechnology Pty Limited Subsetting brain data

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9023111D0 (en) * 1990-10-24 1990-12-05 Wellcome Found Expression system

Also Published As

Publication number Publication date
WO1996002634A1 (en) 1996-02-01
DK0773991T3 (da) 2004-10-25
ES2222465T3 (es) 2005-02-01
DE69533135T2 (de) 2005-06-16
JPH10503645A (ja) 1998-04-07
CA2194763A1 (en) 1996-02-01
EP0773991A1 (en) 1997-05-21
JP4429385B2 (ja) 2010-03-10
DE69533135D1 (en) 2004-07-15
US6057143A (en) 2000-05-02
ATE268816T1 (de) 2004-06-15
AU3003395A (en) 1996-02-16
US5869336A (en) 1999-02-09
EP0773991A4 (en) 1999-06-23
EP0773991B1 (en) 2004-06-09

Similar Documents

Publication Publication Date Title
PT773991E (pt) Calpaina activa expressa por baculovirus
DE69635026D1 (de) Varianten des menschlichen wachstumshormons
ATE162221T1 (de) Herstellung von glukoseoxidase in rekombinanten systemen
IL149459A0 (en) Recombinant gelatins
ES2192620T3 (es) Polipeptido receptor de il-13.
ATE271058T1 (de) Mycophenol bisphosponatverbindungen
ES2163638T3 (es) Nuevas n-(1-alquil-5-fenil-2,3,4,5-tetrahidro-1h-benzo(b)(1,5)diacepin-3-il)acetamidas.
DK175391D0 (da) Nye enzymer
ES2164731T3 (es) Suspension acuosa tixotropica de agentes fitoprotectores.
DE122011000008I1 (de) Herstellung enzymatischer aktiver glukocerebrosidase von rekombinanten zellen.
AU5720498A (en) Chemical synthesis of nucleosides analogs and their incorporation into polynucleotides
SE9303788D0 (sv) Biomedicinsk elektrod
DK1040191T3 (da) RANTES-mutanter og terapeutiske anvendelser heraf
BG101787A (en) Aprotinine options having improved properties
ATE203272T1 (de) Rekombinant dns kodierend für eine endochitinase
DE69734596D1 (de) "smoothened" proteine aus wirbeltieren
ES2149244T3 (es) Procedimientos para producir proteina c.
AU695849B2 (en) Contact lenses with hydrophilic crosslinkers
CA2261041A1 (en) Bacillus thuringiensis strains showing improved production of certain lepidopteran-toxic crystal proteins
ES2060385T3 (es) Nuevos vectores de clonacion y/o de expresion, procedimiento de preparacion y su utilizacion.
DE69022560D1 (de) N,N'-hydrocarbylen-bis-(N-hals)-substituierte Amidhydrazide.
DE60044528D1 (de) Bazillus zelle für die herstellung von proteinen
RO100770B1 (ro) Compozitie pe baza de ebonita pentru fabricarea lampilor de mina