PT833847E - Cristais de fragmentos de ligando cd40 e sua utilizacao - Google Patents

Cristais de fragmentos de ligando cd40 e sua utilizacao

Info

Publication number
PT833847E
PT833847E PT96922527T PT96922527T PT833847E PT 833847 E PT833847 E PT 833847E PT 96922527 T PT96922527 T PT 96922527T PT 96922527 T PT96922527 T PT 96922527T PT 833847 E PT833847 E PT 833847E
Authority
PT
Portugal
Prior art keywords
crystals
connecting fragment
fragment crystals
ligand
relates
Prior art date
Application number
PT96922527T
Other languages
English (en)
Inventor
Juswinder Singh
Mikhail N Arpusas
David W Thomas
Original Assignee
Biogen Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biogen Inc filed Critical Biogen Inc
Publication of PT833847E publication Critical patent/PT833847E/pt

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/525—Tumour necrosis factor [TNF]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70575—NGF/TNF-superfamily, e.g. CD70, CD95L, CD153, CD154

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Chemistry (AREA)
  • Cell Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Peptides Or Proteins (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Analysing Materials By The Use Of Radiation (AREA)
  • Compounds Of Alkaline-Earth Elements, Aluminum Or Rare-Earth Metals (AREA)
PT96922527T 1995-06-22 1996-06-21 Cristais de fragmentos de ligando cd40 e sua utilizacao PT833847E (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US44895P 1995-06-22 1995-06-22

Publications (1)

Publication Number Publication Date
PT833847E true PT833847E (pt) 2004-02-27

Family

ID=21691579

Family Applications (1)

Application Number Title Priority Date Filing Date
PT96922527T PT833847E (pt) 1995-06-22 1996-06-21 Cristais de fragmentos de ligando cd40 e sua utilizacao

Country Status (10)

Country Link
EP (1) EP0833847B1 (pt)
JP (2) JPH11508262A (pt)
AT (1) ATE250630T1 (pt)
AU (1) AU6337296A (pt)
CA (1) CA2224812A1 (pt)
DE (1) DE69630120T2 (pt)
DK (1) DK0833847T3 (pt)
ES (1) ES2202455T3 (pt)
PT (1) PT833847E (pt)
WO (1) WO1997000895A1 (pt)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5834228A (en) * 1997-02-13 1998-11-10 Merck & Co., Inc. Method for identifying inhibitors for apopain based upon the crystal structure of the apopain: Ac-DEVD-CHO complex
EP1754490A3 (en) 1997-06-20 2010-01-20 Biogen Idec MA Inc. CD 154 blockage therapy for pancreatic islet tissue transplantation in primates
SK16742000A3 (sk) 1998-05-12 2001-07-10 Warner-Lambert Company Kombinácie proteínovej farnesyltransferázy a inhibítorov hmg coa reduktázy a ich použitie pri liečbe rakoviny
AU8867501A (en) * 2000-09-01 2002-03-13 Biogen Inc Co-crystal structure of monoclonal antibody 5c8 and cd154, and use thereof in drug design
CN100439397C (zh) 2001-02-09 2008-12-03 基因技术股份有限公司 Igf-1的结晶
WO2013036829A1 (en) 2011-09-09 2013-03-14 Genentech, Inc Treatment of th17 mediated inflammatory diseases
CN112151122B (zh) * 2020-09-10 2025-02-21 国家纳米科学中心 结构未知晶体衍射能力的计算方法及物相定量分析方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2198025T3 (es) * 1991-10-25 2004-01-16 Immunex Corporation Anticuerpos contra cd40-l.
IL104684A0 (en) * 1992-02-14 1993-06-10 Bristol Myers Squibb Co The cd40cr receptor and ligands therefor
US5540926A (en) * 1992-09-04 1996-07-30 Bristol-Myers Squibb Company Soluble and its use in B cell stimulation
AU677995B2 (en) * 1993-01-22 1997-05-15 Immunex Corporation Detection and treatment of mutations in a CD40 ligand gene

Also Published As

Publication number Publication date
CA2224812A1 (en) 1997-01-09
EP0833847B1 (en) 2003-09-24
ATE250630T1 (de) 2003-10-15
JP2006188541A (ja) 2006-07-20
WO1997000895A1 (en) 1997-01-09
JPH11508262A (ja) 1999-07-21
AU6337296A (en) 1997-01-22
DE69630120D1 (de) 2003-10-30
HK1010085A1 (en) 1999-06-11
ES2202455T3 (es) 2004-04-01
EP0833847A1 (en) 1998-04-08
DK0833847T3 (da) 2003-12-29
DE69630120T2 (de) 2004-04-08

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