PT83571B - Process for the preparation of heterocyclic compounds of 1-phenyl-imidazoles and of pharmaceutical compounds containing them - Google Patents

Process for the preparation of heterocyclic compounds of 1-phenyl-imidazoles and of pharmaceutical compounds containing them

Info

Publication number: PT83571B
Authority: PT; Portugal
Prior art keywords: sub; imidazoles; phenyl; preparation; compounds
Prior art date: 1985-10-17

Application number

PT83571A

Other languages

English (en)

Other versions

PT83571A (en

Original Assignee

Ferrosan As

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1985-10-17

Filing date

1986-10-17

Publication date

1988-03-09

1986-10-17 Application filed by Ferrosan As filed Critical Ferrosan As

1986-11-01 Publication of PT83571A publication Critical patent/PT83571A/pt

1988-03-09 Publication of PT83571B publication Critical patent/PT83571B/pt

Links

150000001875 compounds Chemical class 0.000 title abstract 2
238000002360 preparation method Methods 0.000 title abstract 2
150000004842 1-phenylimidazoles Chemical class 0.000 title 1
150000002391 heterocyclic compounds Chemical class 0.000 title 1
UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
230000000895 acaricidal effect Effects 0.000 abstract 1
239000000642 acaricide Substances 0.000 abstract 1
230000000507 anthelmentic effect Effects 0.000 abstract 1
239000000921 anthelmintic agent Substances 0.000 abstract 1
229940124339 anthelmintic agent Drugs 0.000 abstract 1
229940125681 anticonvulsant agent Drugs 0.000 abstract 1
239000001961 anticonvulsive agent Substances 0.000 abstract 1
239000002249 anxiolytic agent Substances 0.000 abstract 1
230000000949 anxiolytic effect Effects 0.000 abstract 1
229940005530 anxiolytics Drugs 0.000 abstract 1
125000000623 heterocyclic group Chemical group 0.000 abstract 1
229910052739 hydrogen Inorganic materials 0.000 abstract 1
239000001257 hydrogen Substances 0.000 abstract 1
239000003326 hypnotic agent Substances 0.000 abstract 1
230000000147 hypnotic effect Effects 0.000 abstract 1
239000002917 insecticide Substances 0.000 abstract 1
239000002664 nootropic agent Substances 0.000 abstract 1
230000001777 nootropic effect Effects 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/10—Anthelmintics
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains three hetero rings
- C07D487/14—Ortho-condensed systems
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
- C07D513/04—Ortho-condensed systems

Landscapes

Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Chemical Kinetics & Catalysis (AREA)
Public Health (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Neurosurgery (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Tropical Medicine & Parasitology (AREA)
Pain & Pain Management (AREA)
Anesthesiology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Plural Heterocyclic Compounds (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Agricultural Chemicals And Associated Chemicals (AREA)
Lubricants (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Cosmetics (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)

PT83571A 1985-10-17 1986-10-17 Process for the preparation of heterocyclic compounds of 1-phenyl-imidazoles and of pharmaceutical compounds containing them PT83571B (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
DK476885A DK476885D0 (da)	1985-10-17	1985-10-17	Heterocycliske forbindelser og fremgangsmaader til fremstilling heraf

Publications (2)

Publication Number	Publication Date
PT83571A PT83571A (en)	1986-11-01
PT83571B true PT83571B (en)	1988-03-09

Family

ID=8136485

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
PT83572A PT83572B (pt)	1985-10-17	1986-10-17	Processo para a preparacao de compostos heterociclicos de quinoxalina e de composicoes farmaceuticas que os contem
PT83571A PT83571B (en)	1985-10-17	1986-10-17	Process for the preparation of heterocyclic compounds of 1-phenyl-imidazoles and of pharmaceutical compounds containing them

Family Applications Before (1)

Application Number	Title	Priority Date	Filing Date
PT83572A PT83572B (pt)	1985-10-17	1986-10-17	Processo para a preparacao de compostos heterociclicos de quinoxalina e de composicoes farmaceuticas que os contem

Country Status (18)

Country	Link
US (5)	US4870073A (pt)
EP (2)	EP0225013B1 (pt)
JP (2)	JPS62155278A (pt)
KR (1)	KR940010034B1 (pt)
AT (1)	ATE48844T1 (pt)
AU (2)	AU591937B2 (pt)
CA (2)	CA1293723C (pt)
DE (1)	DE3667665D1 (pt)
DK (1)	DK476885D0 (pt)
ES (1)	ES2014234B3 (pt)
FI (2)	FI864124A7 (pt)
GR (1)	GR3000367T3 (pt)
IE (1)	IE59642B1 (pt)
IL (1)	IL80319A (pt)
NO (2)	NO864061L (pt)
NZ (2)	NZ217958A (pt)
PH (1)	PH22556A (pt)
PT (2)	PT83572B (pt)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DK476885D0 (da) *	1985-10-17	1985-10-17	Ferrosan As	Heterocycliske forbindelser og fremgangsmaader til fremstilling heraf
ATE80392T1 (de) *	1985-10-17	1992-09-15	Novo Nordisk As	Oxadiazolylacetonitrile, ihre herstellung und anwendung.
DK174086D0 (da) *	1986-04-16	1986-04-16	Ferrosan As	Nye benzodiazepinderivater samt fremgangsmaade til fremstilling af samme
DK155524C (da) *	1987-03-18	1989-09-11	Ferrosan As	Kondenserede imidazolderivater og farmaceutiske praeparater indeholdende disse
DK160876C (da) *	1987-12-08	1991-10-14	Novo Nordisk As	Imidazoquinoxalinforbindelser, fremgangsmaade til deres fremstilling, anvendelse af forbindelserne og farmaceutiske praeparater, hvori forbindelserne indgaar
IL90315A0 (en) *	1988-06-01	1989-12-15	Ferrosan As	Imidazoquinoxaline compounds,their preparation and pharmaceutical compositions containing them
DK161148C (da) *	1988-06-14	1991-11-18	Novo Nordisk As	Imidazoquinoxalinforbindelser, fremgangsmaade til fremstilling deraf samt farmaceutiske praeprater indeholdende forbindelserne
GB8823475D0 (en) *	1988-10-06	1988-11-16	Merck Sharp & Dohme	Chemical compounds
DK626288D0 (da) *	1988-11-10	1988-11-10	Ferrosan As	Kemisk proces til fremstilling af imidazoquinoxaliner og mellemprodukter til brug i processen
EP0389189B1 (en) *	1989-03-23	1994-05-18	Pfizer Limited	Diazepine antiallergy agents
DK443589D0 (da) *	1989-09-08	1989-09-08	Ferrosan As	Heterocykliske forbindelser, deres fremstilling og anvendelse
DK588489D0 (da) *	1989-11-22	1989-11-22	Ferrosan As	Heterocykliske forbindelser, deres fremstilling og anvendelse
DK588389D0 (da) *	1989-11-22	1989-11-22	Ferrosan As	Heterocykliske forbindelser, deres fremstilling og anvendelse
US5371080A (en) *	1990-06-22	1994-12-06	Novo Nordisk A/S	Imidazoquinazoline compounds and their use
DK151890D0 (da) *	1990-06-22	1990-06-22	Ferrosan As	Heterocykliske forbindelser deres fremstilling og brug
US5276028A (en) *	1990-06-22	1994-01-04	Nordisk A/S	Imidazoquinoxaline compounds
DK41191D0 (da) *	1991-03-07	1991-03-07	Novo Nordisk As	Heterocycliske forbindelser, deres fremstilling og anvendelse
KR100207360B1 (ko) *	1991-06-14	1999-07-15	돈 더블유. 슈미츠	이미다조[1,5,-a]퀸옥살린
US5561227A (en) *	1991-07-23	1996-10-01	Schering Corporation	Process for the stereospecific synthesis of azetidinones
TW223059B (pt) *	1991-07-23	1994-05-01	Schering Corp
AU4035893A (en) *	1991-12-17	1993-07-19	Upjohn Company, The	3-substituted imidazo (1,5-a) and imidazo (1,5-a)-triazolo (1,5-c) quinoxalines and quinazolines with cns activity
US5244906A (en) *	1992-01-23	1993-09-14	Dowelanco	Insect control with substituted oxadiazole and thiadiazole compounds
ES2177539T3 (es) *	1992-02-13	2002-12-16	Upjohn Co	Benzoxacinas 4-oxo- y 4h-imidazo(5,1-c)(1,4) utilez como agentes de union de receptores de benzodiacepina.
GB9212486D0 (en) *	1992-06-12	1992-07-22	Erba Carlo Spa	Derivatives of substituted imidazo benzoxazin-1-one and process for their preparation
CA2143246C (en) *	1994-03-16	2000-08-22	Thierry Godel	Imidazodiazepines
GB2328940B (en) *	1997-09-05	1999-12-08	Dong Kook Pharm Co Ltd	A process for preparing benzodiazepine derivatives
WO2007087250A2 (en) *	2006-01-23	2007-08-02	Amira Pharmaceuticals, Inc.	Tricyclic inhibitors of 5-lipoxygenase
US20100234359A1 (en) *	2007-08-20	2010-09-16	Evotec Neurosciences Gmbh	Treatment of sleep disorders
US20090054412A1 (en) *	2007-08-20	2009-02-26	John Alan Kemp	Treatment of Sleep Disorders
JO3156B1 (ar)	2009-07-09	2017-09-20	Novartis Ag	ايميدازولات مدمجة والتركيبات التي تشملها لعلاج الأمراض الطفيلية على مثال الملاريا
EP3377493B1 (en)	2015-11-20	2020-04-08	Forma Therapeutics, Inc.	Purinones as ubiquitin-specific protease 1 inhibitors
AU2018260414A1 (en)	2017-04-24	2019-10-17	Novartis Ag	Therapeutic regimen of 2-amino-l-(2-(4-fluorophenyl)-3-(4-fluorophenylamino)-8,8-dimethyl-5,6-dihydroimidazo[1,2-a]pyrazin-7(8H)-yl)ethanone and combinations thereof

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4118386A (en) *	1977-04-04	1978-10-03	Hoffmann-La Roche Inc.	Synthesis of imidazo[1,5-a]diazepine-3-carboxylates
US4668678A (en) *	1980-05-09	1987-05-26	Usv Pharmaceutical Corporation	Triazoloquinoxalin-1,4-diones
CA1184175A (en) *	1981-02-27	1985-03-19	Walter Hunkeler	Imidazodiazepines
US4440929A (en) *	1981-07-16	1984-04-03	Usv Pharmaceutical Corporation	Imidazoquinoxaline compounds
DK151808C (da) *	1982-11-16	1988-06-20	Ferrosan As	Analogifremgangsmaade til fremstilling af oxadiazolylimidazo-oe1,4aa-benzodiazepinderivater
EP0150040B1 (de) *	1984-01-19	1994-08-31	F. Hoffmann-La Roche Ag	Imidazodiazepin-Derivate
DK476885D0 (da) *	1985-10-17	1985-10-17	Ferrosan As	Heterocycliske forbindelser og fremgangsmaader til fremstilling heraf
US4771051A (en) *	1985-05-17	1988-09-13	A/S Ferrosan	3-substituted-4,5-dihydro-5-oxo imidazoquinazolines, their preparation, and their use in treating benzodiazepin receptor-related ailments
ATE80392T1 (de) *	1985-10-17	1992-09-15	Novo Nordisk As	Oxadiazolylacetonitrile, ihre herstellung und anwendung.
FR2598147B1 (fr) *	1986-04-30	1988-08-26	Pasteur Institut	Immunogene isole de mollusques, son procede de preparation, reactifs de diagnostic des bilharzioses humaines, vaccins contre les schistosomiases et compositions immunisantes comprenant ledit immunogene.

1985
- 1985-10-17 DK DK476885A patent/DK476885D0/da not_active Application Discontinuation
1986
- 1986-09-26 US US06/912,777 patent/US4870073A/en not_active Expired - Fee Related
- 1986-09-26 US US06/912,776 patent/US4774245A/en not_active Expired - Fee Related
- 1986-10-01 ES ES86307542T patent/ES2014234B3/es not_active Expired - Lifetime
- 1986-10-01 EP EP86307542A patent/EP0225013B1/en not_active Expired
- 1986-10-01 CA CA000519556A patent/CA1293723C/en not_active Expired - Lifetime
- 1986-10-01 DE DE8686307542T patent/DE3667665D1/de not_active Expired - Lifetime
- 1986-10-01 EP EP86307543A patent/EP0220845A1/en not_active Withdrawn
- 1986-10-01 AT AT86307542T patent/ATE48844T1/de not_active IP Right Cessation
- 1986-10-01 CA CA000519557A patent/CA1275411C/en not_active Expired - Lifetime
- 1986-10-13 FI FI864124A patent/FI864124A7/fi not_active IP Right Cessation
- 1986-10-13 NO NO864061A patent/NO864061L/no unknown
- 1986-10-13 FI FI864125A patent/FI82050C/fi not_active IP Right Cessation
- 1986-10-13 NO NO864062A patent/NO163776C/no unknown
- 1986-10-15 IL IL80319A patent/IL80319A/xx not_active IP Right Cessation
- 1986-10-16 IE IE273386A patent/IE59642B1/en not_active IP Right Cessation
- 1986-10-16 NZ NZ217958A patent/NZ217958A/xx unknown
- 1986-10-16 PH PH34375A patent/PH22556A/en unknown
- 1986-10-16 NZ NZ217957A patent/NZ217957A/xx unknown
- 1986-10-17 AU AU64179/86A patent/AU591937B2/en not_active Ceased
- 1986-10-17 PT PT83572A patent/PT83572B/pt not_active IP Right Cessation
- 1986-10-17 PT PT83571A patent/PT83571B/pt unknown
- 1986-10-17 JP JP61247306A patent/JPS62155278A/ja active Pending
- 1986-10-17 KR KR1019860008728A patent/KR940010034B1/ko not_active Expired - Fee Related
- 1986-10-17 AU AU64178/86A patent/AU6417886A/en not_active Abandoned
- 1986-10-17 JP JP61247307A patent/JPH0753731B2/ja not_active Expired - Lifetime
1987
- 1987-10-13 US US07/108,272 patent/US4795749A/en not_active Expired - Fee Related
1989
- 1989-02-02 US US07/305,969 patent/US4886797A/en not_active Expired - Fee Related
- 1989-02-02 US US07/305,970 patent/US4880799A/en not_active Expired - Fee Related
1990
- 1990-03-01 GR GR90400114T patent/GR3000367T3/el unknown

Also Published As

Publication number	Publication date
NO864062D0 (no)	1986-10-13
FI864124A7 (fi)	1987-04-18
AU591937B2 (en)	1989-12-21
IL80319A (en)	1990-03-19
US4870073A (en)	1989-09-26
EP0225013B1 (en)	1989-12-20
PT83571A (en)	1986-11-01
KR940010034B1 (ko)	1994-10-21
NO163776B (no)	1990-04-09
CA1275411C (en)	1990-10-23
JPS62161785A (ja)	1987-07-17
KR870004032A (ko)	1987-05-07
AU6417886A (en)	1987-04-30
PT83572A (en)	1986-11-01
ATE48844T1 (de)	1990-01-15
US4774245A (en)	1988-09-27
NZ217958A (en)	1989-02-24
CA1293723C (en)	1991-12-31
US4880799A (en)	1989-11-14
AU6417986A (en)	1987-04-30
IE59642B1 (en)	1994-03-09
DK476885D0 (da)	1985-10-17
NO864062L (no)	1987-04-21
NZ217957A (en)	1989-02-24
US4795749A (en)	1989-01-03
FI864124A0 (fi)	1986-10-13
GR3000367T3 (en)	1991-06-07
FI864125A7 (fi)	1987-04-18
DE3667665D1 (de)	1990-01-25
FI82050B (fi)	1990-09-28
FI82050C (fi)	1991-01-10
ES2014234B3 (es)	1990-07-01
EP0225013A1 (en)	1987-06-10
NO864061L (no)	1987-04-21
NO864061D0 (no)	1986-10-13
PH22556A (en)	1988-10-17
EP0220845A1 (en)	1987-05-06
US4886797A (en)	1989-12-12
JPS62155278A (ja)	1987-07-10
PT83572B (pt)	1988-10-14
IE862733L (en)	1987-04-17
FI864125A0 (fi)	1986-10-13
JPH0753731B2 (ja)	1995-06-07
NO163776C (no)	1990-07-18

Publication	Publication Date	Title
PT83571A (en)	1986-11-01	Process for the preparation of heterocyclic compounds of 1-phenyl-imidazoles and of pharmaceutical compounds containing them
EP0221041A3 (en)	1987-10-28	Benzimidazole derivatives, process for their preparation and their pharmaceutical use
PT86186A (en)	1987-12-01	Process for the preparation of benzimidazol derivatives and of pharmaceutical compositions containing the same
ZA885192B (en)	1989-04-26	Pharmaceutical preparations
HUT45021A (en)	1988-05-30	Process for production of insecticides and acaricides containing pirasoline-derivatives as active substance and process for production of the active substances
GR3006091T3 (pt)	1993-06-21
SE8700555L (sv)	1987-08-15	Purinderivat, deras framstellning och lekemedel innehallande dessa
ES8200684A1 (es)	1981-11-01	Procedimiento para la preparacion de sulfonilureas
SE8500962D0 (sv)	1985-02-27	Nitrodiaryl sulfoxide derivatives, process for their preparation and pharmaceutical and pesticidal compositions containing them as active ingredient
ES8103041A1 (es)	1981-02-16	Procedimiento para la preparacion de sulfonilsemicarbazidas
GR3001809T3 (en)	1992-11-23	Benzylaminoaryldihydropyridine lactones, process for their preparation and their use in medicaments