PT866791E - Diaminopirimidinas formulacoes farmaceuticas que as contem e sua utilizacao antibacteriana - Google Patents
Diaminopirimidinas formulacoes farmaceuticas que as contem e sua utilizacao antibacterianaInfo
- Publication number
- PT866791E PT866791E PT96939890T PT96939890T PT866791E PT 866791 E PT866791 E PT 866791E PT 96939890 T PT96939890 T PT 96939890T PT 96939890 T PT96939890 T PT 96939890T PT 866791 E PT866791 E PT 866791E
- Authority
- PT
- Portugal
- Prior art keywords
- diaminopyrimidines
- antibacterial
- utilization
- contain
- pharmaceutical formulations
- Prior art date
Links
- 229940058936 antimalarials diaminopyrimidines Drugs 0.000 title abstract 2
- 230000000844 anti-bacterial effect Effects 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- 125000006527 (C1-C5) alkyl group Chemical group 0.000 abstract 1
- 208000035473 Communicable disease Diseases 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 230000003115 biocidal effect Effects 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 125000004435 hydrogen atom Chemical class [H]* 0.000 abstract 1
- 230000002265 prevention Effects 0.000 abstract 1
- MISVBCMQSJUHMH-UHFFFAOYSA-N pyrimidine-4,6-diamine Chemical class NC1=CC(N)=NC=N1 MISVBCMQSJUHMH-UHFFFAOYSA-N 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
- C07D239/48—Two nitrogen atoms
- C07D239/49—Two nitrogen atoms with an aralkyl radical, or substituted aralkyl radical, attached in position 5, e.g. trimethoprim
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
- C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
- C07D311/64—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4 with oxygen atoms directly attached in position 8
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH342595 | 1995-12-04 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PT866791E true PT866791E (pt) | 2002-05-31 |
Family
ID=4255709
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT96939890T PT866791E (pt) | 1995-12-04 | 1996-11-22 | Diaminopirimidinas formulacoes farmaceuticas que as contem e sua utilizacao antibacteriana |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US5773446A (pt) |
| EP (2) | EP0866791B1 (pt) |
| JP (1) | JP3309340B2 (pt) |
| KR (1) | KR100417207B1 (pt) |
| CN (1) | CN1092194C (pt) |
| AT (1) | ATE212629T1 (pt) |
| AU (1) | AU708578B2 (pt) |
| BR (1) | BR9611871B1 (pt) |
| CA (1) | CA2238521C (pt) |
| DE (1) | DE69618986T2 (pt) |
| DK (1) | DK0866791T3 (pt) |
| ES (1) | ES2169272T3 (pt) |
| MX (1) | MX9804416A (pt) |
| PT (1) | PT866791E (pt) |
| TR (1) | TR199801014T2 (pt) |
| WO (1) | WO1997020839A1 (pt) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TW438796B (en) * | 1996-05-15 | 2001-06-07 | Hoffmann La Roche | 2,4-diaminopyrimidine derivatives, the manufacture process thereof, and the antibiotically-active pharmaceutical composition containing the same |
| AU2001252269A1 (en) * | 2000-04-27 | 2001-11-12 | Basilea Pharmaceutica Ag | Chromenylmethyl pyrimidinediamines as antibacterial agents |
| WO2002010156A1 (en) * | 2000-07-29 | 2002-02-07 | Arpida Ag | Benzofuran derivatives and their use as antibacterial agents |
| WO2005014586A1 (en) * | 2003-08-08 | 2005-02-17 | Arpida Ag | Novel process for the preparation of 2h-chromenes |
| BRPI0607758A2 (pt) * | 2005-02-18 | 2010-03-23 | Arpida Ag | processos para a fabricaÇço do composto e para a reduÇço do composto, e, composto |
| US20090069357A1 (en) * | 2007-09-09 | 2009-03-12 | Protia, Llc | Deuterium-enriched iclaprim |
| US7947293B2 (en) | 2008-04-08 | 2011-05-24 | Arpida Ag | Aqueous pharmaceutical formulation |
| JP2011516509A (ja) * | 2008-04-08 | 2011-05-26 | アシノ ファーマ アーゲー | 水性医薬製剤 |
| EP3452042A1 (en) | 2016-05-04 | 2019-03-13 | Motif Biosciences, Inc. | Systems and methods for treating bacterial infection |
| CN110139648A (zh) * | 2016-11-11 | 2019-08-16 | 莫迪福生物科学股份有限公司 | 治疗细菌感染的制剂、方法、试剂盒和剂型 |
| CN110498812B (zh) * | 2018-05-17 | 2021-08-24 | 上海医药工业研究院 | 一种艾拉普林的中间体化合物的制备方法 |
| CN110606831A (zh) * | 2018-06-14 | 2019-12-24 | 上海度德医药科技有限公司 | 一种Iclaprim的新中间体及其制备方法和应用 |
| CN110818693B (zh) * | 2018-08-07 | 2023-06-02 | 上海度德医药科技有限公司 | 一种艾拉普林甲磺酸盐晶型b及其制备方法 |
| WO2020161284A1 (en) | 2019-02-07 | 2020-08-13 | Sandoz Ag | Crystalline form of iclaprim mesylate |
| CN109988156B (zh) * | 2019-03-12 | 2021-12-28 | 广东中科药物研究有限公司 | 一种氨基嘧啶化合物 |
| CN113493461A (zh) * | 2020-04-01 | 2021-10-12 | 上海医药工业研究院 | 一种七元杂环化合物或其盐、其制备方法及应用 |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4438267A (en) * | 1980-11-11 | 1984-03-20 | Daluge Susan M | Monoheteroring compounds and their use |
-
1996
- 1996-11-22 WO PCT/EP1996/005151 patent/WO1997020839A1/en not_active Ceased
- 1996-11-22 DK DK96939890T patent/DK0866791T3/da active
- 1996-11-22 DE DE69618986T patent/DE69618986T2/de not_active Expired - Lifetime
- 1996-11-22 PT PT96939890T patent/PT866791E/pt unknown
- 1996-11-22 TR TR1998/01014T patent/TR199801014T2/xx unknown
- 1996-11-22 BR BRPI9611871-7A patent/BR9611871B1/pt not_active IP Right Cessation
- 1996-11-22 AT AT96939890T patent/ATE212629T1/de active
- 1996-11-22 KR KR10-1998-0704199A patent/KR100417207B1/ko not_active Expired - Fee Related
- 1996-11-22 CN CN96198783A patent/CN1092194C/zh not_active Expired - Fee Related
- 1996-11-22 EP EP96939890A patent/EP0866791B1/en not_active Expired - Lifetime
- 1996-11-22 JP JP52092597A patent/JP3309340B2/ja not_active Expired - Fee Related
- 1996-11-22 ES ES96939890T patent/ES2169272T3/es not_active Expired - Lifetime
- 1996-11-22 AU AU76963/96A patent/AU708578B2/en not_active Ceased
- 1996-11-22 EP EP01117420A patent/EP1149834A1/en not_active Withdrawn
- 1996-11-22 CA CA002238521A patent/CA2238521C/en not_active Expired - Fee Related
- 1996-12-02 US US08/758,993 patent/US5773446A/en not_active Expired - Lifetime
-
1998
- 1998-06-03 MX MX9804416A patent/MX9804416A/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| DK0866791T3 (da) | 2002-04-22 |
| CN1092194C (zh) | 2002-10-09 |
| CA2238521C (en) | 2005-08-16 |
| DE69618986T2 (de) | 2002-06-20 |
| BR9611871B1 (pt) | 2010-11-03 |
| AU7696396A (en) | 1997-06-27 |
| US5773446A (en) | 1998-06-30 |
| EP0866791A1 (en) | 1998-09-30 |
| TR199801014T2 (xx) | 1998-09-21 |
| CN1203600A (zh) | 1998-12-30 |
| ATE212629T1 (de) | 2002-02-15 |
| JP2000501399A (ja) | 2000-02-08 |
| AU708578B2 (en) | 1999-08-05 |
| DE69618986D1 (de) | 2002-03-14 |
| CA2238521A1 (en) | 1997-06-12 |
| KR100417207B1 (ko) | 2004-04-17 |
| WO1997020839A1 (en) | 1997-06-12 |
| MX9804416A (es) | 1998-09-30 |
| JP3309340B2 (ja) | 2002-07-29 |
| ES2169272T3 (es) | 2002-07-01 |
| KR19990071912A (ko) | 1999-09-27 |
| BR9611871A (pt) | 1999-02-17 |
| EP0866791B1 (en) | 2002-01-30 |
| EP1149834A1 (en) | 2001-10-31 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| MY115662A (en) | Novel compounds with analgesic effect | |
| NZ244021A (en) | Benzylthiazolidinedione derivatives, preparation and pharmaceutical compositions thereof | |
| AU6194694A (en) | Nor-bile acid derivatives, processes for their preparation and the use of these compounds as medicaments | |
| GR3026218T3 (en) | Antiviral 4-substituted-2-deoxy-2,3-didehydro derivatives of alpha D-neuraminic acid | |
| IL109526A0 (en) | Benzofuranyl- and thiophenyl-alkanecarboxylic acid derivatives, their preparation and pharmaceutical compositions containing them | |
| ATE175669T1 (de) | Sulfonylaminopyrimidine, ihre herstellung und verwendung als heilmittel | |
| ATE290015T1 (de) | Cyclosporinderivate, deren herstellung und pharmazeutische zubereitungen | |
| ES2102475T3 (es) | Nuevas alquil-amidas heterociclicas, su procedimiento de preparacion y composiciones farmaceuticas que las contienen. | |
| DE69713151D1 (de) | Cyclosporinderivat, dessen herstellung und pharmazeutische zusammensetzung | |
| DE59409794D1 (de) | Benzoylguanidine, ihre herstellung und ihre verwendung in arzneimitteln | |
| PT847757E (pt) | Medicamento que compreende o gene de hgf | |
| ES2169272T3 (es) | Diaminopirimidinas, composiciones farmaceuticas que las contienen y su utilizacion como agente antibacteriano. | |
| PT876388E (pt) | Derivados de eritromicina triciclica | |
| ES2052065T3 (es) | Formulacion dispersable. | |
| AU7263591A (en) | Benzisothiazolinone-1-dioxide derivatives as elastase inhibitors | |
| EP0712844A4 (en) | NEW CONDENSED CARBONIC ACID OR YOUR SALT AND YOUR MEDICAL USE | |
| DE69521275D1 (de) | Pharmazeutische Zubereitungen enthaltend Cefaclor | |
| DK0824539T3 (da) | Dialkyltiacumicin-forbindelser | |
| PT986386E (pt) | Uso de derivados heterociclicos aromaticos com azoto no tratamento topico de doencas dos tecidos epiteliais | |
| SE9504662D0 (sv) | New compounds | |
| CA2047802A1 (en) | Pharmaceutical compositions | |
| AU1643592A (en) | Novel compound and use of the same as medicine | |
| DE60003074D1 (de) | Fusidinsäure-derivate | |
| GR3024709T3 (en) | Novel cytarabine derivatives, their production and use |