PT86772A - Process for preparing human interleukin-3 and muteins thereof - Google Patents

Process for preparing human interleukin-3 and muteins thereof

Info

Publication number
PT86772A
PT86772A PT86772A PT8677288A PT86772A PT 86772 A PT86772 A PT 86772A PT 86772 A PT86772 A PT 86772A PT 8677288 A PT8677288 A PT 8677288A PT 86772 A PT86772 A PT 86772A
Authority
PT
Portugal
Prior art keywords
muteins
human interleukin
preparing human
preparing
interleukin
Prior art date
Application number
PT86772A
Other languages
English (en)
Other versions
PT86772B (pt
Inventor
Takeshi Otsuka
Original Assignee
Schering Biotech Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Biotech Corp filed Critical Schering Biotech Corp
Publication of PT86772A publication Critical patent/PT86772A/pt
Publication of PT86772B publication Critical patent/PT86772B/pt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52Cytokines; Lymphokines; Interferons
    • C07K14/54Interleukins [IL]
    • C07K14/5403IL-3
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Biophysics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Immunology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
PT86772A 1987-02-18 1988-02-17 Processo para a preparacao de interleuquina-3 humana e de suas muteinas PT86772B (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US1607987A 1987-02-18 1987-02-18

Publications (2)

Publication Number Publication Date
PT86772A true PT86772A (pt) 1988-03-01
PT86772B PT86772B (pt) 1992-05-29

Family

ID=21775278

Family Applications (1)

Application Number Title Priority Date Filing Date
PT86772A PT86772B (pt) 1987-02-18 1988-02-17 Processo para a preparacao de interleuquina-3 humana e de suas muteinas

Country Status (16)

Country Link
EP (2) EP0355093A1 (pt)
JP (1) JPH02500328A (pt)
KR (1) KR890700608A (pt)
CN (1) CN88100685A (pt)
AR (1) AR243240A1 (pt)
AU (1) AU626789B2 (pt)
FI (1) FI893872A7 (pt)
HU (1) HU204890B (pt)
IL (1) IL85444A0 (pt)
MY (1) MY102806A (pt)
NZ (1) NZ223551A (pt)
OA (1) OA09736A (pt)
PT (1) PT86772B (pt)
TN (1) TNSN88013A1 (pt)
WO (1) WO1988006161A1 (pt)
ZA (1) ZA881109B (pt)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GR871029B (en) * 1986-07-14 1987-11-02 Genetics Inst Novel osteoinductive factors
EP0342206A4 (en) * 1987-01-20 1990-09-19 Immunex Corporation Human interleukin-3 proteins
US5304637A (en) * 1987-07-13 1994-04-19 Gist-Brocades N.V. Expression and purification of human interleukin-3 and muteins thereof
US6384194B1 (en) 1987-12-16 2002-05-07 Dsm N.V. Expression and purification of human interleukin-3 and muteins thereof
AU3864089A (en) * 1988-07-20 1990-02-19 Immunex Corporation Nonglycosylated human interleukin-3 compositions
US5128450A (en) * 1989-06-30 1992-07-07 Urdal David L Nonglycosylated human interleukin-3 analog proteins
DE69030937T2 (de) * 1989-08-14 1997-10-09 Gist Brocades Nv Mutanten von Interleukin-3
US5516512A (en) 1989-08-14 1996-05-14 Gist-Brocades, N.V. N- and C-terminal truncation and deletion mutants of human interleukin-3
JP3115318B2 (ja) * 1989-08-22 2000-12-04 イミュネックス・コーポレーション Gm―csf及びil―3を含む融合タンパク質
US5108910A (en) * 1989-08-22 1992-04-28 Immunex Corporation DNA sequences encoding fusion proteins comprising GM-CSF and IL-3
US5073627A (en) * 1989-08-22 1991-12-17 Immunex Corporation Fusion proteins comprising GM-CSF and IL-3
US7049102B1 (en) 1989-09-22 2006-05-23 Board Of Trustees Of Leland Stanford University Multi-gene expression profile
ATE179211T1 (de) * 1991-10-07 1999-05-15 Medvet Science Pty Ltd Menschliche il-3-varianten
US5376367A (en) * 1991-11-22 1994-12-27 Immunex Corporation Fusion proteins comprising MGF and IL-3
US5738849A (en) * 1992-11-24 1998-04-14 G. D. Searle & Co. Interleukin-3 (IL-3) variant fusion proteins, their recombinant production, and therapeutic compositions comprising them
US6361976B1 (en) 1992-11-24 2002-03-26 S. Christopher Bauer Co-administration of interleukin-3 mutant polypeptides with CSF'S for multi-lineage hematopoietic cell production
US6403076B1 (en) 1992-11-24 2002-06-11 S. Christopher Bauer Compositions for increasing hematopoiesis with interleukin-3 mutants
US6153183A (en) * 1992-11-24 2000-11-28 G. D. Searle & Company Co-administration of interleukin-3 mutant polypeptides with CSF's or cytokines for multi-lineage hematopoietic cell production
JPH08503706A (ja) * 1992-11-24 1996-04-23 ジー.ディー.サール アンド カンパニー インターロイキン−3(il−3)多重変異ポリペプチド
US5501962A (en) * 1993-06-21 1996-03-26 G. D. Searle & Co. Interleuken-3 (IL-3) human/murine hybrid polypeptides and recombinant production of the same
US5631219A (en) * 1994-03-08 1997-05-20 Somatogen, Inc. Method of stimulating hematopoiesis with hemoglobin
US6242417B1 (en) 1994-03-08 2001-06-05 Somatogen, Inc. Stabilized compositions containing hemoglobin
US6017523A (en) * 1995-06-06 2000-01-25 G.D. Searle & Co. Therapeutic methods employing mutant human interleukin-3 (IL-3) polypeptides
EA199800272A1 (ru) 1995-10-04 1998-10-29 Иммунекс Корпорейшн Фактор, стимулирующий дендритные клетки
JP5099951B2 (ja) 1999-11-12 2012-12-19 バクスター・インターナショナル・インコーポレイテッド 副作用が減少されたヘモグロビン組成物
JP2008527981A (ja) * 2005-01-25 2008-07-31 アポロ ライフ サイエンシズ リミテッド 治療目的および診断目的のためにパラメーターにより選択されたgm−csf、il−3、il−4、il−5、ならびにそのキメラ
SG11201404741VA (en) 2012-02-07 2014-09-26 Global Bio Therapeutics Usa Inc Compartmentalized method of nucleic acid delivery and compositions and uses thereof
CN105813579B (zh) 2013-08-08 2019-05-07 全球生物疗法有限公司 用于微创手术过程的夹具装置和其应用
CN112195177B (zh) * 2020-10-28 2021-08-06 上海慕柏生物医学科技有限公司 一种核酸提取方法及试剂盒

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS60207594A (ja) * 1984-03-30 1985-10-19 Ajinomoto Co Inc ヒトインタ−ロイキン3の製造方法
GR871029B (en) * 1986-07-14 1987-11-02 Genetics Inst Novel osteoinductive factors
AU617095B2 (en) * 1986-12-16 1991-11-21 Dsm N.V. Molecular cloning and expression of human il-3

Also Published As

Publication number Publication date
EP0355093A1 (en) 1990-02-28
FI893872A0 (fi) 1989-08-17
IL85444A0 (en) 1988-07-31
ZA881109B (en) 1988-08-17
OA09736A (en) 1993-11-30
MY102806A (en) 1992-11-30
HUT50872A (en) 1990-03-28
CN88100685A (zh) 1988-12-14
AR243240A1 (es) 1993-07-30
AU1429488A (en) 1988-09-14
PT86772B (pt) 1992-05-29
WO1988006161A1 (en) 1988-08-25
FI893872A7 (fi) 1989-08-17
TNSN88013A1 (fr) 1990-07-10
AU626789B2 (en) 1992-08-13
KR890700608A (ko) 1989-04-26
JPH02500328A (ja) 1990-02-08
EP0282185A1 (en) 1988-09-14
NZ223551A (en) 1991-02-26
HU204890B (en) 1992-02-28

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Legal Events

Date Code Title Description
FG3A Patent granted, date of granting

Effective date: 19911118

MM3A Annulment or lapse

Free format text: LAPSE DUE TO NON-PAYMENT OF FEES

Effective date: 19950531