PT87122A - Process for preparing psychotropic polycyclic imides - Google Patents
Process for preparing psychotropic polycyclic imidesInfo
- Publication number
- PT87122A PT87122A PT87122A PT8712288A PT87122A PT 87122 A PT87122 A PT 87122A PT 87122 A PT87122 A PT 87122A PT 8712288 A PT8712288 A PT 8712288A PT 87122 A PT87122 A PT 87122A
- Authority
- PT
- Portugal
- Prior art keywords
- carbon atoms
- metheno
- chem
- taken together
- attached
- Prior art date
Links
- 150000003949 imides Chemical class 0.000 title abstract 2
- 238000004519 manufacturing process Methods 0.000 title 1
- 230000000506 psychotropic effect Effects 0.000 title 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 8
- -1 trifluoromethylphenyl Chemical group 0.000 abstract 6
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 2
- 125000004450 alkenylene group Chemical group 0.000 abstract 1
- 125000005036 alkoxyphenyl group Chemical group 0.000 abstract 1
- 125000005037 alkyl phenyl group Chemical group 0.000 abstract 1
- 125000002947 alkylene group Chemical group 0.000 abstract 1
- 150000008064 anhydrides Chemical class 0.000 abstract 1
- 230000000561 anti-psychotic effect Effects 0.000 abstract 1
- 239000002249 anxiolytic agent Substances 0.000 abstract 1
- 229910052799 carbon Inorganic materials 0.000 abstract 1
- 125000000753 cycloalkyl group Chemical group 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 125000005059 halophenyl group Chemical group 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 125000004435 hydrogen atom Chemical class [H]* 0.000 abstract 1
- UZGLIIJVICEWHF-UHFFFAOYSA-N octogen Chemical compound [O-][N+](=O)N1CN([N+]([O-])=O)CN([N+]([O-])=O)CN([N+]([O-])=O)C1 UZGLIIJVICEWHF-UHFFFAOYSA-N 0.000 abstract 1
- QEFOMGYMQQNSIU-UHFFFAOYSA-N pentalene-1,3-dicarboxylic acid Chemical compound C1=CC=C2C(C(=O)O)=CC(C(O)=O)=C21 QEFOMGYMQQNSIU-UHFFFAOYSA-N 0.000 abstract 1
- 125000004307 pyrazin-2-yl group Chemical group [H]C1=C([H])N=C(*)C([H])=N1 0.000 abstract 1
- 125000000246 pyrimidin-2-yl group Chemical group [H]C1=NC(*)=NC([H])=C1[H] 0.000 abstract 1
- 125000005493 quinolyl group Chemical group 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/12—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains three hetero rings
- C07D491/18—Bridged systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C61/00—Compounds having carboxyl groups bound to carbon atoms of rings other than six-membered aromatic rings
- C07C61/12—Saturated polycyclic compounds
- C07C61/125—Saturated polycyclic compounds having a carboxyl group bound to a condensed ring system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
- C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
- C07D221/22—Bridged ring systems
- C07D221/24—Camphidines
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D313/00—Heterocyclic compounds containing rings of more than six members having one oxygen atom as the only ring hetero atom
- C07D313/02—Seven-membered rings
- C07D313/06—Seven-membered rings condensed with carbocyclic rings or ring systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Neurology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biomedical Technology (AREA)
- Pharmacology & Pharmacy (AREA)
- Psychiatry (AREA)
- Animal Behavior & Ethology (AREA)
- Neurosurgery (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Indole Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Plural Heterocyclic Compounds (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Epoxy Resins (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Pyrrole Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US07/034,820 US4797488A (en) | 1987-04-03 | 1987-04-03 | Psychotropic polycyclic imides |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| PT87122A true PT87122A (pt) | 1988-04-01 |
| PT87122B PT87122B (pt) | 1992-07-31 |
Family
ID=21878820
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT87122A PT87122B (pt) | 1987-04-03 | 1988-03-30 | Processo para a preparacao de imidas policiclicas psicotropicas |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US4797488A (pt) |
| EP (1) | EP0286263B1 (pt) |
| JP (1) | JPH01502756A (pt) |
| KR (1) | KR960001478B1 (pt) |
| AT (1) | ATE63551T1 (pt) |
| AU (2) | AU597480B2 (pt) |
| CA (1) | CA1306251C (pt) |
| DE (1) | DE3862793D1 (pt) |
| ES (1) | ES2039617T3 (pt) |
| GB (1) | GB2203428B (pt) |
| GR (1) | GR3001959T3 (pt) |
| IE (1) | IE61957B1 (pt) |
| PT (1) | PT87122B (pt) |
| WO (1) | WO1988007529A1 (pt) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2601366B1 (fr) * | 1986-07-10 | 1988-11-25 | Andre Buzas | Derives de la benzhydryloxyethyl-piperazine, procedes d'obtention et de compositions pharmaceutiques les contenant. |
| US4994455A (en) * | 1987-10-26 | 1991-02-19 | Pfizer Inc. | Anti-anxiety agents |
| HU207310B (en) * | 1988-12-02 | 1993-03-29 | Pfizer | Process for producing aryl-piperidine derivatives |
| DE68918832T2 (de) * | 1988-12-28 | 1995-02-09 | Suntory Ltd | Benzoxazepinderivate. |
| US4968792A (en) * | 1989-09-25 | 1990-11-06 | American Home Products Corporation | Psychotropic benzisothiazole derivatives |
| US4957913A (en) * | 1989-11-22 | 1990-09-18 | American Home Products Corp. | Antihypertensive polycyclic imides |
| US5053508A (en) * | 1990-03-09 | 1991-10-01 | American Home Products Corporation | Fused heterotricyclic imides with psychotropic activity and intermedrates thereof |
| US5219983A (en) * | 1991-05-08 | 1993-06-15 | Phillips Petroleum Company | Preparation of poly (biphenylene/phenylene) sulfide |
| US5134141A (en) * | 1991-09-06 | 1992-07-28 | American Home Products Corporation | Antidepressant polycyclic imides to treat depression |
| US5183819A (en) * | 1992-05-11 | 1993-02-02 | American Home Products Corporation | Use of fused bicyclic imides in the treatment of various CNS disorders |
| US5631017A (en) * | 1993-03-26 | 1997-05-20 | Beth Israel Deaconess Medical Center, Inc. | Topical application of buspirone for treatment of pathological conditions associated with immune responses |
| US5484788A (en) * | 1993-03-26 | 1996-01-16 | Beth Israel Hospital Association | Buspirone as a systemic immunosuppressant |
| US5670696A (en) * | 1994-09-02 | 1997-09-23 | Arakawa Chemical Industires Ltd. | Alicyclic bifunctional compounds and processes for their preparation |
| US5637314A (en) * | 1995-06-07 | 1997-06-10 | Beth Israel Deaconess Medical Center, Inc. | Topical and systemic application of buspirone or derivatives thereof for treating atopic dermatitis |
| EP1495000A4 (en) * | 2002-04-08 | 2005-10-05 | Ranbaxy Lab Ltd | ALPHA, OMEGA DICARBOXIMID DERIVATIVES SUITED AS UROSELECTIVE A1A ADRENEOCEPTOR BLOCKERS |
| US20060247249A1 (en) * | 2005-11-16 | 2006-11-02 | Mohammad Salman | Carboximide derivatives as useful uro-selective alpha-1a adrenoceptor blockers |
| CN102223945A (zh) | 2008-11-26 | 2011-10-19 | 东丽东燃机能膜合同会社 | 微孔膜、该微孔膜的制备方法以及该微孔膜作为电池隔膜的应用 |
| CN102153567B (zh) * | 2010-05-28 | 2013-08-14 | 重庆天地药业有限责任公司 | 一种制备头孢西丁酸的方法 |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BE759371A (fr) * | 1969-11-24 | 1971-05-24 | Bristol Myers Co | Azaspirodecanediones heterocycliques et procedes pour leur preparation |
| US4305944A (en) * | 1980-09-08 | 1981-12-15 | Mead Johnson & Company | N-[(4-[3-cyano substituted pyridyl]piperazino)alkyl]-azaspirodecanediones |
| US4507303A (en) * | 1981-12-22 | 1985-03-26 | Sumitomo Chemical Company, Limited | Succinimide derivatives, compositions and method of use |
| JPS6087284A (ja) * | 1983-10-19 | 1985-05-16 | Sumitomo Chem Co Ltd | コハク酸イミド誘導体及びその酸付加塩 |
| US4562255A (en) * | 1984-03-30 | 1985-12-31 | American Home Products Corporation | Substituted bi-alicyclic imides |
| CA1286672C (en) * | 1985-10-16 | 1991-07-23 | Magid A. Abou-Gharbia | Fused bicyclic imides with psychotropic activity |
| US4675403A (en) * | 1985-10-16 | 1987-06-23 | American Home Products Corporation | 3-Aminoalkyl derivatives of 5,5-disubstituted hydantoins with psychotropic activity |
| US4732984A (en) * | 1985-10-17 | 1988-03-22 | American Home Products Corporation | Piperazinoisothiazolones with psychotropic activity |
| US4748240A (en) * | 1987-04-03 | 1988-05-31 | American Home Products Corporation | Psychotropic bicyclic imides |
| US4732983A (en) * | 1987-04-03 | 1988-03-22 | American Home Products Corporation | Pyschotropic polycyclic imides |
| US4994455A (en) * | 1987-10-26 | 1991-02-19 | Pfizer Inc. | Anti-anxiety agents |
-
1987
- 1987-04-03 US US07/034,820 patent/US4797488A/en not_active Expired - Lifetime
-
1988
- 1988-03-18 CA CA000561882A patent/CA1306251C/en not_active Expired - Fee Related
- 1988-03-22 GB GB8806778A patent/GB2203428B/en not_active Expired - Fee Related
- 1988-03-22 ES ES198888302499T patent/ES2039617T3/es not_active Expired - Lifetime
- 1988-03-22 EP EP88302499A patent/EP0286263B1/en not_active Expired - Lifetime
- 1988-03-22 DE DE8888302499T patent/DE3862793D1/de not_active Expired - Fee Related
- 1988-03-22 AT AT88302499T patent/ATE63551T1/de not_active IP Right Cessation
- 1988-03-23 AU AU13512/88A patent/AU597480B2/en not_active Ceased
- 1988-03-30 IE IE96388A patent/IE61957B1/en not_active IP Right Cessation
- 1988-03-30 PT PT87122A patent/PT87122B/pt not_active IP Right Cessation
- 1988-03-31 JP JP63503414A patent/JPH01502756A/ja active Pending
- 1988-03-31 WO PCT/US1988/000973 patent/WO1988007529A1/en not_active Ceased
- 1988-03-31 KR KR1019880701590A patent/KR960001478B1/ko not_active Expired - Fee Related
-
1990
- 1990-03-08 AU AU51158/90A patent/AU617930B2/en not_active Ceased
-
1991
- 1991-05-16 GR GR91400611T patent/GR3001959T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| ATE63551T1 (de) | 1991-06-15 |
| CA1306251C (en) | 1992-08-11 |
| AU5115890A (en) | 1990-06-28 |
| EP0286263A1 (en) | 1988-10-12 |
| PT87122B (pt) | 1992-07-31 |
| AU1351288A (en) | 1988-10-06 |
| AU617930B2 (en) | 1991-12-05 |
| DE3862793D1 (en) | 1991-06-20 |
| KR960001478B1 (ko) | 1996-01-31 |
| IE61957B1 (en) | 1994-11-30 |
| GB2203428A (en) | 1988-10-19 |
| AU597480B2 (en) | 1990-05-31 |
| GR3001959T3 (en) | 1992-11-23 |
| EP0286263B1 (en) | 1991-05-15 |
| ES2039617T3 (es) | 1993-10-01 |
| GB2203428B (en) | 1990-10-31 |
| KR890700592A (ko) | 1989-04-26 |
| WO1988007529A1 (en) | 1988-10-06 |
| GB8806778D0 (en) | 1988-04-20 |
| US4797488A (en) | 1989-01-10 |
| IE880963L (en) | 1988-10-03 |
| JPH01502756A (ja) | 1989-09-21 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG3A | Patent granted, date of granting |
Effective date: 19920122 |
|
| MM3A | Annulment or lapse |
Free format text: LAPSE DUE TO NON-PAYMENT OF FEES Effective date: 19960731 |