PT874631E - Utilizacao de valaciclovir para a manufactura de um medicamento para o tratamento de herpes genital por aplicacao diaria unica - Google Patents

Utilizacao de valaciclovir para a manufactura de um medicamento para o tratamento de herpes genital por aplicacao diaria unica

Info

Publication number: PT874631E
Authority: PT; Portugal
Prior art keywords: valaciclovir; genital herpes; pharmaceutically acceptable; acceptable salt; suppression
Prior art date: 1996-01-19

Application number

PT97901052T

Other languages

English (en)

Inventor

John Delehanty

Margaret L Smiley

Original Assignee

Glaxo Group Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1996-01-19

Filing date

1997-01-17

Publication date

2004-04-30

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=24399659&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PT874631(E) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

1997-01-17 Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd

2004-04-30 Publication of PT874631E publication Critical patent/PT874631E/pt

Links

HDOVUKNUBWVHOX-QMMMGPOBSA-N Valacyclovir Chemical compound N1C(N)=NC(=O)C2=C1N(COCCOC(=O)[C@@H](N)C(C)C)C=N2 HDOVUKNUBWVHOX-QMMMGPOBSA-N 0.000 title abstract 6
229940093257 valacyclovir Drugs 0.000 title abstract 6
208000001688 Herpes Genitalis Diseases 0.000 title abstract 5
201000004946 genital herpes Diseases 0.000 title abstract 5
238000004519 manufacturing process Methods 0.000 title 1
229940126601 medicinal product Drugs 0.000 title 1
150000003839 salts Chemical class 0.000 abstract 4
230000001629 suppression Effects 0.000 abstract 3
MKUXAQIIEYXACX-UHFFFAOYSA-N aciclovir Chemical compound N1C(N)=NC(=O)C2=C1N(COCCO)C=N2 MKUXAQIIEYXACX-UHFFFAOYSA-N 0.000 abstract 2
239000002552 dosage form Substances 0.000 abstract 2
230000000306 recurrent effect Effects 0.000 abstract 2
QCQCHGYLTSGIGX-GHXANHINSA-N 4-[[(3ar,5ar,5br,7ar,9s,11ar,11br,13as)-5a,5b,8,8,11a-pentamethyl-3a-[(5-methylpyridine-3-carbonyl)amino]-2-oxo-1-propan-2-yl-4,5,6,7,7a,9,10,11,11b,12,13,13a-dodecahydro-3h-cyclopenta[a]chrysen-9-yl]oxy]-2,2-dimethyl-4-oxobutanoic acid Chemical compound N([C@@]12CC[C@@]3(C)[C@]4(C)CC[C@H]5C(C)(C)[C@@H](OC(=O)CC(C)(C)C(O)=O)CC[C@]5(C)[C@H]4CC[C@@H]3C1=C(C(C2)=O)C(C)C)C(=O)C1=CN=CC(C)=C1 QCQCHGYLTSGIGX-GHXANHINSA-N 0.000 abstract 1
KZSNJWFQEVHDMF-UHFFFAOYSA-N Valine Natural products CC(C)C(N)C(O)=O KZSNJWFQEVHDMF-UHFFFAOYSA-N 0.000 abstract 1
229960004150 aciclovir Drugs 0.000 abstract 1
239000003443 antiviral agent Substances 0.000 abstract 1
239000002775 capsule Substances 0.000 abstract 1
239000003814 drug Substances 0.000 abstract 1
238000000034 method Methods 0.000 abstract 1
239000008194 pharmaceutical composition Substances 0.000 abstract 1
239000004474 valine Substances 0.000 abstract 1
-1 valine ester Chemical class 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
- A61K31/52—Purines, e.g. adenine
- A61K31/522—Purines, e.g. adenine having oxo groups directly attached to the heterocyclic ring, e.g. hypoxanthine, guanine, acyclovir
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
- A61P31/22—Antivirals for DNA viruses for herpes viruses

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Medicinal Chemistry (AREA)
Virology (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Chemical & Material Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Communicable Diseases (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Organic Chemistry (AREA)
Chemical Kinetics & Catalysis (AREA)
Oncology (AREA)
Biotechnology (AREA)
Molecular Biology (AREA)
Engineering & Computer Science (AREA)
Epidemiology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicinal Preparation (AREA)
Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

PT97901052T 1996-01-19 1997-01-17 Utilizacao de valaciclovir para a manufactura de um medicamento para o tratamento de herpes genital por aplicacao diaria unica PT874631E (pt)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US59944896A	1996-01-19	1996-01-19

Publications (1)

Publication Number	Publication Date
PT874631E true PT874631E (pt)	2004-04-30

Family

ID=24399659

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
PT97901052T PT874631E (pt)	1996-01-19	1997-01-17	Utilizacao de valaciclovir para a manufactura de um medicamento para o tratamento de herpes genital por aplicacao diaria unica

Country Status (12)

Country	Link
EP (1)	EP0874631B1 (pt)
JP (1)	JP4097698B2 (pt)
AT (1)	ATE254463T1 (pt)
AU (1)	AU722304B2 (pt)
CA (1)	CA2243237C (pt)
CY (1)	CY2512B1 (pt)
DE (1)	DE69726255T2 (pt)
DK (1)	DK0874631T3 (pt)
ES (1)	ES2210490T3 (pt)
PT (1)	PT874631E (pt)
WO (1)	WO1997025989A1 (pt)
ZA (1)	ZA97400B (pt)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB0010446D0 (en) *	2000-04-28	2000-06-14	Glaxo Wellcome Kk	Pharmaceutical formulation
ITMI20010009A1 (it) *	2001-01-03	2002-07-03	Menarini Ricerche Spa	Composizioni farmaceutica contenente brivudina per la singola somministrazione giornaliera
EP1436295A4 (en) *	2001-09-07	2007-07-11	Teva Pharma	CRISTALLINE FORMS OF VALACYCLOVIR HYDROCHLORIDE
CA2649826A1 (en) *	2001-11-14	2003-05-22	Teva Pharmaceutical Industries Ltd.	Synthesis and purification of valacyclovir
US7229644B2 (en) *	2002-05-23	2007-06-12	Cephalon, Inc.	Pharmaceutical formulations of modafinil
US20060147519A1 (en) *	2002-06-24	2006-07-06	Ashish Gogia	Process for the preparation of robust formulations of valacyclovir hydrochloride tablets
US20040116532A1 (en) *	2002-09-13	2004-06-17	Craig Heacock	Pharmaceutical formulations of modafinil
US7786302B2 (en) *	2003-05-30	2010-08-31	Eczacibasi-Zentiva Kimyasal Urunler Sanayi Ve Ticaret A.S.	Crystalline forms of valacyclovir hydrochloride
CN1331471C (zh) *	2003-09-22	2007-08-15	陈云芳	盐酸万乃洛韦软胶囊组合物
WO2007090595A1 (en) *	2006-02-06	2007-08-16	Fidia Pharmaceutici S.P.A.	Solid formulations of valacyclovir hydrochloride
GB0605344D0 (en) *	2006-03-17	2006-04-26	Pliva Istrazivanje I Razvoj D	Pharmaceutically acceptable salts and polymorphic forms
JP4669804B2 (ja) *	2006-03-28	2011-04-13	株式会社オーディオテクニカ	コンデンサマイクロホン
CN1903854B (zh) *	2006-08-09	2012-05-23	丽珠医药集团股份有限公司	一种合成盐酸伐昔洛韦的方法
JPWO2009031576A1 (ja) *	2007-09-03	2010-12-16	味の素株式会社	バラシクロビル塩酸塩結晶の製造方法
CN104188928B (zh) *	2014-09-17	2017-07-28	山东新时代药业有限公司	一种盐酸伐昔洛韦片剂及其制备方法
WO2020049536A1 (en) *	2018-09-07	2020-03-12	Jubilant Generics Limited	Pharmaceutical compositions of valacyclovir or its pharmaceutically acceptable salts thereof
CN109651371B (zh) *	2018-12-31	2021-02-23	辰欣药业股份有限公司	一种盐酸伐昔洛韦的制备方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
AP55A (en) *	1987-08-15	1989-09-26	The Wellcome Foundation Ltd	Therapeutic Acyclic Nucleosides
GB9320316D0 (en) *	1993-10-01	1993-11-17	Smithkline Beecham Plc	Pharmaceuticals
GB9501127D0 (en) *	1995-01-20	1995-03-08	Wellcome Found	Tablet
GB9501178D0 (en) *	1995-01-20	1995-03-08	Wellcome Found	Guanine derivative

1997
- 1997-01-17 AT AT97901052T patent/ATE254463T1/de not_active IP Right Cessation
- 1997-01-17 ES ES97901052T patent/ES2210490T3/es not_active Expired - Lifetime
- 1997-01-17 JP JP52569197A patent/JP4097698B2/ja not_active Expired - Fee Related
- 1997-01-17 ZA ZA9700400A patent/ZA97400B/xx unknown
- 1997-01-17 CA CA002243237A patent/CA2243237C/en not_active Expired - Fee Related
- 1997-01-17 DK DK97901052T patent/DK0874631T3/da active
- 1997-01-17 EP EP97901052A patent/EP0874631B1/en not_active Revoked
- 1997-01-17 AU AU14434/97A patent/AU722304B2/en not_active Ceased
- 1997-01-17 PT PT97901052T patent/PT874631E/pt unknown
- 1997-01-17 WO PCT/EP1997/000192 patent/WO1997025989A1/en not_active Ceased
- 1997-01-17 DE DE69726255T patent/DE69726255T2/de not_active Expired - Lifetime
2005
- 2005-04-18 CY CY0500026A patent/CY2512B1/xx unknown

Also Published As

Publication number	Publication date
CA2243237C (en)	2008-09-02
EP0874631B1 (en)	2003-11-19
CA2243237A1 (en)	1997-07-24
CY2512B1 (en)	2005-12-23
EP0874631A1 (en)	1998-11-04
WO1997025989A1 (en)	1997-07-24
JP2000503310A (ja)	2000-03-21
AU722304B2 (en)	2000-07-27
DE69726255D1 (de)	2003-12-24
ATE254463T1 (de)	2003-12-15
AU1443497A (en)	1997-08-11
DE69726255T2 (de)	2004-08-26
ES2210490T3 (es)	2004-07-01
ZA97400B (en)	1997-11-13
DK0874631T3 (da)	2004-03-22
JP4097698B2 (ja)	2008-06-11

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