PT88244A - Processo para a preparacao de derivados de tetrazole antagonistas de leucotrienos - Google Patents

Processo para a preparacao de derivados de tetrazole antagonistas de leucotrienos

Info

Publication number
PT88244A
PT88244A PT88244A PT8824488A PT88244A PT 88244 A PT88244 A PT 88244A PT 88244 A PT88244 A PT 88244A PT 8824488 A PT8824488 A PT 8824488A PT 88244 A PT88244 A PT 88244A
Authority
PT
Portugal
Prior art keywords
leukotrienes
preparation
tetrazole derivatives
antagonists
derivatives antagonists
Prior art date
Application number
PT88244A
Other languages
English (en)
Other versions
PT88244B (pt
Inventor
Winston Stanley Marshall
Sandr Kay Sigmund
Celia Ann Whitesitt
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of PT88244A publication Critical patent/PT88244A/pt
Publication of PT88244B publication Critical patent/PT88244B/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D257/00—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms
    • C07D257/02—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D257/04—Five-membered rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Pulmonology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Immunology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
PT88244A 1987-08-14 1988-08-11 Processo para a preparacao de derivados de tetrazole antagonistas de leucotrienos PT88244B (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/085,588 US4820723A (en) 1987-08-14 1987-08-14 Disubstituted tetrazole leukotriene antagonists and methods for their use thereas

Publications (2)

Publication Number Publication Date
PT88244A true PT88244A (pt) 1989-06-30
PT88244B PT88244B (pt) 1995-03-01

Family

ID=22192636

Family Applications (1)

Application Number Title Priority Date Filing Date
PT88244A PT88244B (pt) 1987-08-14 1988-08-11 Processo para a preparacao de derivados de tetrazole antagonistas de leucotrienos

Country Status (14)

Country Link
US (1) US4820723A (pt)
EP (1) EP0303478B1 (pt)
JP (1) JPS6466174A (pt)
KR (1) KR890003716A (pt)
CN (1) CN1012434B (pt)
AU (1) AU610218B2 (pt)
DE (1) DE3875030T2 (pt)
DK (1) DK449388A (pt)
ES (1) ES2052730T3 (pt)
HU (1) HUT50462A (pt)
NZ (1) NZ225791A (pt)
PH (1) PH26259A (pt)
PT (1) PT88244B (pt)
ZA (1) ZA885887B (pt)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4820722A (en) * 1987-08-14 1989-04-11 Eli Lilly And Company Disubstituted tetrazoles and their use as leukotriene antagonists
ATE135000T1 (de) * 1989-07-14 1996-03-15 Ciba Geigy Ag Substituierte benzonitrile
DE4124942A1 (de) * 1991-07-27 1993-01-28 Thomae Gmbh Dr K 5-gliedrige heterocyclen, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
CN101544614B (zh) * 2008-03-24 2011-07-20 合肥合源药业有限公司 磷酸二酯酶ⅲ抑制剂、其制法及其医药用途
SI3083564T1 (sl) * 2013-12-20 2018-10-30 Novartis Ag Derivati heteroarilbutanojske kisline kot inhibitorji LTA4H
CA3105542A1 (en) 2018-07-31 2020-02-06 Novartis Ag Crystalline forms of a lta4h inhibitor

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4661505A (en) * 1982-11-03 1987-04-28 Eli Lilly And Company Leukotriene antagonists
US4663332A (en) * 1985-10-10 1987-05-05 Hoffman-La Roche Inc. 5-substituted N-alkylated tetrazoles
PT85110A (en) * 1986-06-23 1987-07-01 Merck Frosst Canada Inc Process for preparing benzenealkanoic acid derivatives useful as leukotriene antagonists
CA1315279C (en) * 1987-01-12 1993-03-30 Nancy Grace Bollinger Anti-inflammatory agents

Also Published As

Publication number Publication date
JPS6466174A (en) 1989-03-13
NZ225791A (en) 1990-10-26
AU610218B2 (en) 1991-05-16
KR890003716A (ko) 1989-04-17
US4820723A (en) 1989-04-11
DK449388D0 (da) 1988-08-11
HUT50462A (en) 1990-02-28
AU2096788A (en) 1989-02-16
CN1012434B (zh) 1991-04-24
DE3875030D1 (de) 1992-11-05
DE3875030T2 (de) 1993-03-04
DK449388A (da) 1989-02-15
PH26259A (en) 1992-04-01
ES2052730T3 (es) 1994-07-16
CN1031224A (zh) 1989-02-22
PT88244B (pt) 1995-03-01
EP0303478A1 (en) 1989-02-15
EP0303478B1 (en) 1992-09-30
ZA885887B (en) 1990-04-25

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Legal Events

Date Code Title Description
FG3A Patent granted, date of granting

Effective date: 19940808

MM3A Annulment or lapse

Free format text: LAPSE DUE TO NON-PAYMENT OF FEES

Effective date: 19960229