PT90266A - Processo para a preparacao de compostos azabiciclicos - Google Patents

Processo para a preparacao de compostos azabiciclicos

Info

Publication number
PT90266A
PT90266A PT90266A PT9026689A PT90266A PT 90266 A PT90266 A PT 90266A PT 90266 A PT90266 A PT 90266A PT 9026689 A PT9026689 A PT 9026689A PT 90266 A PT90266 A PT 90266A
Authority
PT
Portugal
Prior art keywords
preparation
azabicylic
compounds
azabicylic compounds
Prior art date
Application number
PT90266A
Other languages
English (en)
Other versions
PT90266B (pt
Inventor
Michael Stewart Hadley
Barry Sidney Orlek
Steven Mark Bromidge
Original Assignee
Beecham Group Plc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB888808925A external-priority patent/GB8808925D0/en
Priority claimed from GB888812602A external-priority patent/GB8812602D0/en
Priority claimed from GB888824076A external-priority patent/GB8824076D0/en
Application filed by Beecham Group Plc filed Critical Beecham Group Plc
Publication of PT90266A publication Critical patent/PT90266A/pt
Publication of PT90266B publication Critical patent/PT90266B/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/08—Bridged systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D453/00—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
    • C07D453/02—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/08—Bridged systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
PT90266A 1988-04-15 1989-04-13 Processo para a preparacao de compostos azabiciclicos PT90266B (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB888808925A GB8808925D0 (en) 1988-04-15 1988-04-15 Novel compounds
GB888812602A GB8812602D0 (en) 1988-05-27 1988-05-27 Novel compounds
GB888824076A GB8824076D0 (en) 1988-10-13 1988-10-13 Novel compounds

Publications (2)

Publication Number Publication Date
PT90266A true PT90266A (pt) 1989-11-10
PT90266B PT90266B (pt) 1994-07-29

Family

ID=27263861

Family Applications (1)

Application Number Title Priority Date Filing Date
PT90266A PT90266B (pt) 1988-04-15 1989-04-13 Processo para a preparacao de compostos azabiciclicos

Country Status (8)

Country Link
US (1) US5110828A (pt)
EP (1) EP0338723B1 (pt)
JP (1) JP2917224B2 (pt)
KR (1) KR900016203A (pt)
AU (1) AU3301689A (pt)
DE (1) DE68907982T2 (pt)
DK (1) DK177889A (pt)
PT (1) PT90266B (pt)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1227436B (it) * 1988-10-28 1991-04-11 Roussel Maestretti Spa Derivati di 1-azabicicloalcani, loro procedimento di preparazione e loro applicazione come farmaci
US5183893A (en) * 1988-10-28 1993-02-02 Roussel Uclaf 1-azabicycloalkane derivatives, their preparation process and their use as medicaments
US4937239A (en) * 1989-02-13 1990-06-26 Warner-Lambert Company Azabicycloalkane oxime & azabicycloalkene oxime muscarinic agents
US5278170A (en) * 1989-04-13 1994-01-11 Beecham Group P.L.C. Azabicylo oxime compounds
DK0392803T3 (da) * 1989-04-13 2004-10-18 Beecham Group Plc Hidtil ukendte forbindelser
ATE153024T1 (de) * 1989-08-16 1997-05-15 Beecham Group Plc Azabicyclische verbindungen
IE912974A1 (en) * 1990-08-24 1992-02-26 Beecham Group Plc Novel compounds
GB9019095D0 (en) * 1990-09-01 1990-10-17 Beecham Group Plc Novel compounds
JPH06501933A (ja) * 1990-10-12 1994-03-03 ビーチャム・グループ・パブリック・リミテッド・カンパニー １，２，５，６−テトラヒドロピリジン・オキシム誘導体
WO1993008191A1 (en) * 1991-10-15 1993-04-29 Warner-Lambert Company Azabicyclo oxime and amine cholinergic agents and methods of treatment
US5190953A (en) * 1992-03-26 1993-03-02 A. H. Robins Company, Incorporated Heterocyclic carboxylic acid amides and esters of azabicyclic compounds as gastric prokinetic, antiemetic, anxiolytic and antiarrhythmic agents
US5244907A (en) * 1992-03-26 1993-09-14 A. H. Robins Company, Incorporated Carbocyclic carboxylic acid amides and esters of azabicyclic compounds as gastric prokinetic, antiemetic, anxiolytic and antiarrhythmic agents
IT1255179B (it) * 1992-06-26 1995-10-20 Enzo Cereda Azaciclo e azabiciclo alchiliden idrossilamine
JPH11512444A (ja) * 1995-09-22 1999-10-26 ノボ ノルディスク アクティーゼルスカブ 新規置換アザ環式またはアザ二環式化合物
EP2258358A3 (en) 2005-08-26 2011-09-07 Braincells, Inc. Neurogenesis with acetylcholinesterase inhibitor
EP1928437A2 (en) * 2005-08-26 2008-06-11 Braincells, Inc. Neurogenesis by muscarinic receptor modulation
EP2068872A1 (en) 2006-09-08 2009-06-17 Braincells, Inc. Combinations containing a 4-acylaminopyridine derivative

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ203861A (en) * 1982-04-14 1986-07-11 Beecham Group Plc Bicyclic heterocyclic compounds and pharmaceutical compositions containing such
IL81610A (en) * 1986-02-27 1990-12-23 Roussel Uclaf Derivatives of 1,2,5,6-tetrahydropyridin-3-carboxaldehyde oxime,their preparation and pharmaceutical compositions containing them
DE3789039T2 (de) * 1986-06-27 1994-06-09 Beecham Group Plc Verbrückte bicyclische N-heterocyclische Verbindungen.
GB8615785D0 (en) * 1986-06-27 1986-08-06 Beecham Group Plc Compounds
US4786648A (en) * 1986-12-08 1988-11-22 Warner-Lambert Company O-substituted tetrahydropyridine oxime cholinergic agents
US4710508A (en) * 1986-12-08 1987-12-01 Warner-Lambert Company O-substituted tetrahydropyridine oxime cholinergic agents
US4798841A (en) * 1987-03-31 1989-01-17 Warner-Lambert Company Tetrahydropyridine oxime cholinergic agents and method of treatment
EP0287356B1 (en) * 1987-04-15 1996-01-24 Beecham Group Plc Bridgehead substituted azabicyclic derivatives
IT1203971B (it) * 1987-04-24 1989-02-23 Roussel Maestretti Spa Derivati di 1,2,5,6-tetraidropiridina, loro procedimento di preparazione e loro applicazione come medicamenti
IT1222526B (it) * 1987-08-21 1990-09-05 Roussel Maestretti Spa Derivati dell' ossima della 1,2,5,6-tetraidropiridin-3-carbossaldeide,loro procedimento di preparazione e loro impiego come sostanze medicinali
IT1222529B (it) * 1987-08-21 1990-09-05 Roussel Maestretti Spa Derivati dell' ossima della 1,2,5,6-tetraidropirdin-3-carbossaldeide,loro procedimento di preparazione e loro impiego come sostanze medicinali
IL88156A (en) * 1987-11-13 1997-02-18 Novo Nordisk As Azacyclic compounds their preparation and pharmaceutical compositions containing them
IT1233446B (it) * 1987-12-30 1992-04-01 Roussel Maestretti Spa Derivati della 3 piperidinocarbaldeide ossima, loro procedimento di preparazione e loro applicazione come farmaci
US4937239A (en) * 1989-02-13 1990-06-26 Warner-Lambert Company Azabicycloalkane oxime & azabicycloalkene oxime muscarinic agents

Also Published As

Publication number Publication date
DK177889D0 (da) 1989-04-13
DE68907982T2 (de) 1994-01-20
JPH01316376A (ja) 1989-12-21
US5110828A (en) 1992-05-05
KR900016203A (ko) 1990-11-12
EP0338723A1 (en) 1989-10-25
DE68907982D1 (de) 1993-09-09
JP2917224B2 (ja) 1999-07-12
EP0338723B1 (en) 1993-08-04
PT90266B (pt) 1994-07-29
AU3301689A (en) 1989-10-26
DK177889A (da) 1989-10-16

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Legal Events

Date Code Title Description
FG3A Patent granted, date of granting

Effective date: 19940110