PT88663A - Processo para a preparacao de monohidrato e solvatos de um novo antibiotico de beta-lactamo - Google Patents

Processo para a preparacao de monohidrato e solvatos de um novo antibiotico de beta-lactamo

Info

Publication number
PT88663A
PT88663A PT88663A PT8866388A PT88663A PT 88663 A PT88663 A PT 88663A PT 88663 A PT88663 A PT 88663A PT 8866388 A PT8866388 A PT 8866388A PT 88663 A PT88663 A PT 88663A
Authority
PT
Portugal
Prior art keywords
lactamo
solvates
monohydrate
antibiotic
preparation
Prior art date
Application number
PT88663A
Other languages
English (en)
Other versions
PT88663B (pt
Inventor
John Brennan
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of PT88663A publication Critical patent/PT88663A/pt
Publication of PT88663B publication Critical patent/PT88663B/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D463/00—Heterocyclic compounds containing 1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D463/10—Heterocyclic compounds containing 1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
    • C07D463/14—Heterocyclic compounds containing 1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hetero atoms directly attached in position 7
    • C07D463/16—Nitrogen atoms
    • C07D463/18—Nitrogen atoms further acylated by radicals derived from carboxylic acids or by nitrogen or sulfur analogues thereof
    • C07D463/20—Nitrogen atoms further acylated by radicals derived from carboxylic acids or by nitrogen or sulfur analogues thereof with the acylating radicals further substituted by hetero atoms or by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C07D463/22—Nitrogen atoms further acylated by radicals derived from carboxylic acids or by nitrogen or sulfur analogues thereof with the acylating radicals further substituted by hetero atoms or by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen further substituted by nitrogen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cephalosporin Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
PT88663A 1987-10-07 1988-10-04 Processo para a preparacao de monohidrato e solvatos de um novo antibiotico de beta-lactamo PT88663B (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US10576287A 1987-10-07 1987-10-07

Publications (2)

Publication Number Publication Date
PT88663A true PT88663A (pt) 1989-07-31
PT88663B PT88663B (pt) 1993-10-29

Family

ID=22307652

Family Applications (1)

Application Number Title Priority Date Filing Date
PT88663A PT88663B (pt) 1987-10-07 1988-10-04 Processo para a preparacao de monohidrato e solvatos de um novo antibiotico de beta-lactamo

Country Status (24)

Country Link
EP (1) EP0311365A1 (pt)
JP (1) JPH02270871A (pt)
KR (1) KR890006643A (pt)
CN (1) CN1032442A (pt)
AU (1) AU605635B2 (pt)
BG (1) BG47035A3 (pt)
CS (1) CS270593B2 (pt)
DD (1) DD280112A5 (pt)
DK (1) DK553888A (pt)
FI (1) FI884555L (pt)
HU (1) HU205112B (pt)
IL (1) IL87904A0 (pt)
MX (1) MX13276A (pt)
MY (1) MY103554A (pt)
NO (1) NO884417L (pt)
NZ (1) NZ226451A (pt)
OA (1) OA09017A (pt)
PH (1) PH26811A (pt)
PL (2) PL163113B1 (pt)
PT (1) PT88663B (pt)
RO (2) RO105809B1 (pt)
RU (1) RU1776260C (pt)
YU (1) YU46700B (pt)
ZA (1) ZA887408B (pt)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1334970C (en) * 1987-10-06 1995-03-28 Carol Elaine Pasini Crystalline .beta.-lactam hydrate
NZ242556A (en) * 1991-05-10 1993-08-26 Lilly Co Eli Preparation of carbacephem derivatives

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1472746A (en) * 1973-07-05 1977-05-04 Glaxo Lab Ltd Cephalosporin compounds
US4160863A (en) * 1977-04-07 1979-07-10 Bristol-Myers Company Process for the preparation of the crystalline monohydrate of 7-[D-α-aα-(p-hydroxyphenyl)acetamido]-3-methyl-3-cephem-4-carboxylic acid
JPS5672698A (en) * 1979-11-14 1981-06-16 Kyowa Hakko Kogyo Co Ltd Preparation of optically active cephalosporin analogue
CA1334970C (en) * 1987-10-06 1995-03-28 Carol Elaine Pasini Crystalline .beta.-lactam hydrate

Also Published As

Publication number Publication date
CS666588A2 (en) 1989-11-14
NO884417D0 (no) 1988-10-05
ZA887408B (en) 1990-06-27
AU605635B2 (en) 1991-01-17
HUT48883A (en) 1989-07-28
RU1776260C (ru) 1992-11-15
MY103554A (en) 1993-07-31
BG47035A3 (bg) 1990-04-16
PL275092A1 (en) 1989-05-16
CS270593B2 (en) 1990-07-12
RO102423B1 (en) 1992-08-01
HU205112B (en) 1992-03-30
DD280112A5 (de) 1990-06-27
NZ226451A (en) 1990-10-26
JPH02270871A (ja) 1990-11-05
CN1032442A (zh) 1989-04-19
DK553888D0 (da) 1988-10-04
NO884417L (no) 1989-04-10
OA09017A (fr) 1991-03-31
YU184688A (en) 1990-04-30
FI884555A7 (fi) 1989-04-08
FI884555L (fi) 1989-04-08
AU2337188A (en) 1989-04-13
EP0311365A1 (en) 1989-04-12
RO105809B1 (ro) 1992-12-30
PL159766B1 (pl) 1993-01-29
FI884555A0 (fi) 1988-10-04
PH26811A (en) 1992-11-05
KR890006643A (ko) 1989-06-15
PL163113B1 (pl) 1994-02-28
PT88663B (pt) 1993-10-29
DK553888A (da) 1989-04-08
MX13276A (es) 1993-11-01
YU46700B (sh) 1994-04-05
IL87904A0 (en) 1989-03-31

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Legal Events

Date Code Title Description
FG3A Patent granted, date of granting

Effective date: 19930414

MM3A Annulment or lapse

Free format text: LAPSE DUE TO NON-PAYMENT OF FEES

Effective date: 19941031