PT90214A - Processo de preparacao de compostos flavonoides substituidos, dos seus sais e de composicoes farmaceuticas que os contem - Google Patents

Processo de preparacao de compostos flavonoides substituidos, dos seus sais e de composicoes farmaceuticas que os contem

Info

Publication number: PT90214A
Authority: PT; Portugal
Prior art keywords: salts; preparation; pharmaceutical compositions; compositions containing; flavonoid compounds
Prior art date: 1988-04-06

Application number

PT90214A

Other languages

English (en)

Other versions

PT90214B (pt

Inventor

Francois Collonges

Philippe Briet

Jean-Jacques Berthelon

Original Assignee

Lipha

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1988-04-06

Filing date

1989-04-06

Publication date

1989-11-10

1989-04-06 Application filed by Lipha filed Critical Lipha

1989-11-10 Publication of PT90214A publication Critical patent/PT90214A/pt

1994-07-29 Publication of PT90214B publication Critical patent/PT90214B/pt

Links

-1 FLAVONOID COMPOUNDS Chemical class 0.000 title abstract 2
229930003935 flavonoid Natural products 0.000 title abstract 2
235000017173 flavonoids Nutrition 0.000 title abstract 2
239000008194 pharmaceutical composition Substances 0.000 title 1
206010028980 Neoplasm Diseases 0.000 abstract 1
230000001093 anti-cancer Effects 0.000 abstract 1
230000002946 anti-pancreatic effect Effects 0.000 abstract 1
201000011510 cancer Diseases 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
230000000694 effects Effects 0.000 abstract 1
230000002519 immonomodulatory effect Effects 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/20—Oxygen atoms
- C07D215/22—Oxygen atoms attached in position 2 or 4
- C07D215/233—Oxygen atoms attached in position 2 or 4 only one oxygen atom which is attached in position 4
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
- C07D311/22—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
- C07D311/22—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4
- C07D311/26—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with aromatic rings attached in position 2 or 3
- C07D311/28—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with aromatic rings attached in position 2 or 3 with aromatic rings attached in position 2 only
- C07D311/30—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with aromatic rings attached in position 2 or 3 with aromatic rings attached in position 2 only not hydrogenated in the hetero ring, e.g. flavones
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/78—Ring systems having three or more relevant rings
- C07D311/92—Naphthopyrans; Hydrogenated naphthopyrans
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D335/00—Heterocyclic compounds containing six-membered rings having one sulfur atom as the only ring hetero atom
- C07D335/04—Heterocyclic compounds containing six-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D335/06—Benzothiopyrans; Hydrogenated benzothiopyrans
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D345/00—Heterocyclic compounds containing rings having selenium or tellurium atoms as the only ring hetero atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
- C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
- C07D407/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing aromatic rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
- C07D513/04—Ortho-condensed systems
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/655—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having oxygen atoms, with or without sulfur, selenium, or tellurium atoms, as the only ring hetero atoms
- C07F9/6552—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having oxygen atoms, with or without sulfur, selenium, or tellurium atoms, as the only ring hetero atoms the oxygen atom being part of a six-membered ring
- C07F9/65522—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having oxygen atoms, with or without sulfur, selenium, or tellurium atoms, as the only ring hetero atoms the oxygen atom being part of a six-membered ring condensed with carbocyclic rings or carbocyclic ring systems

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
General Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Pharmacology & Pharmacy (AREA)
General Chemical & Material Sciences (AREA)
Animal Behavior & Ethology (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Biochemistry (AREA)
Diabetes (AREA)
Hematology (AREA)
Immunology (AREA)
Molecular Biology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Pyrane Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Peptides Or Proteins (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Heterocyclic Compounds Containing Sulfur Atoms (AREA)
Quinoline Compounds (AREA)
Saccharide Compounds (AREA)

PT90214A 1988-04-06 1989-04-06 Processo de preparacao de compostos flavonoides substituidos, dos seus sais e de composicoes farmaceuticas que os contem PT90214B (pt)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US17831588A	1988-04-06	1988-04-06

Publications (2)

Publication Number	Publication Date
PT90214A true PT90214A (pt)	1989-11-10
PT90214B PT90214B (pt)	1994-07-29

Family

ID=22652061

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
PT90214A PT90214B (pt)	1988-04-06	1989-04-06	Processo de preparacao de compostos flavonoides substituidos, dos seus sais e de composicoes farmaceuticas que os contem

Country Status (20)

Country	Link
EP (1)	EP0341104B1 (pt)
JP (1)	JPH026473A (pt)
AT (1)	ATE99302T1 (pt)
AU (1)	AU630345B2 (pt)
CA (1)	CA1325205C (pt)
DE (1)	DE68911742T2 (pt)
DK (1)	DK166789A (pt)
ES (1)	ES2060799T3 (pt)
HU (1)	HU206701B (pt)
IE (1)	IE62858B1 (pt)
IL (1)	IL89840A (pt)
IN (1)	IN170909B (pt)
MA (1)	MA21528A1 (pt)
NO (1)	NO172344C (pt)
NZ (1)	NZ228625A (pt)
OA (1)	OA09036A (pt)
PT (1)	PT90214B (pt)
SU (1)	SU1739846A3 (pt)
YU (1)	YU47308B (pt)
ZA (1)	ZA892523B (pt)

Families Citing this family (32)

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IL85554A0 (en) *	1987-03-02	1988-08-31	Takeda Chemical Industries Ltd	Chromone derivatives
EP0375819A1 (en) *	1988-12-20	1990-07-04	Merrell Dow Pharmaceuticals Inc.	Novel derivatives of 1,7'-[imidazo-[1,2-a]pyridine]5'-(6'H)ones
WO1990006921A1 (en) *	1988-12-21	1990-06-28	The Upjohn Company	Antiatherosclerotic and antithrombotic 1-benzopyran-4-ones and 2-amino-1,3-benzoxazine-4-ones
US5703075A (en) *	1988-12-21	1997-12-30	Pharmacia & Upjohn Company	Antiatherosclerotic and antithrombotic 1-benzopyran-4-ones and 2-amino-1,3-benzoxazine-4-ones
DE69111595T2 (de) *	1990-11-21	1996-01-18	Polaroid Corp	Squarylium- und crokonyliumfarbstoffe.
US5405976A (en) *	1990-11-21	1995-04-11	Polaroid Corporation	Benzpyrylium squarylium and croconylium dyes, and processes for their preparation and use
US5977351A (en) *	1990-11-21	1999-11-02	Polaroid Corporation	Benzpyrylium squarylium and croconylium dyes, and processes for their preparation and use
WO1994002145A2 (en) *	1992-07-22	1994-02-03	Genelabs Technologies, Inc.	2-aryl-4-quinolones as antitumor compounds
US5571822A (en) *	1994-09-30	1996-11-05	The University Of North Carolina At Chapel Hill	Antitumor compounds
DE19850131A1 (de) *	1998-10-30	2000-05-04	Merck Patent Gmbh	Chromenon- und Chromanonderivate
FI113942B (fi) *	2000-08-18	2004-07-15	Control Ox Oy	Kasviperäisten fenolisten yhdisteiden käyttö valmistettaessa klamydiainfektion hoidossa ja ennaltaehkäisyssä käyttökelpoista farmaseuttista valmistetta, terveyteen myönteisesti vaikuttavaa ravintoainekoostumusta tai koostumusta lisättäväksi tällaisiin elintarvikkeisiin
AU2003234733B2 (en)	2002-04-17	2009-01-29	Cytokinetics, Inc.	Compounds, compositions, and methods
JP2005533119A (ja)	2002-07-17	2005-11-04	サイトキネティクス・インコーポレーテッド	化合物、組成物、及び方法
JP4646626B2 (ja) *	2002-08-16	2011-03-09	アストラゼネカアクチボラグ	ホスホイノシチド３−キナーゼβの阻害
CN101260104A (zh) *	2002-08-16	2008-09-10	阿斯利康(瑞典)有限公司	抑制磷酸肌醇3-激酶β
US8440692B2 (en) *	2006-12-07	2013-05-14	China Medical University	Hydrophilic derivatives of 2-aryl-4-quinolones as anticancer agents
US9326986B2 (en)	2008-09-29	2016-05-03	Glaxosmithkline Llc	Quinazolinone, quinolone and related analogs as sirtuin modulators
WO2011023287A1 (en)	2009-08-27	2011-03-03	Merck Patent Gmbh	Use of faa and its derivatives in cosmetics and dermatology
WO2011029956A1 (en) *	2009-09-14	2011-03-17	Institut National De La Sante Et De La Recherche Medicale (Inserm)	Flavones and flavanones derivates as dna methyltransferases inhibitors
EP2877461B1 (en) *	2012-07-27	2018-05-09	Emory University	Heterocyclic flavone derivatives, compositions, and methods related thereto
CN102977065B (zh) *	2012-12-06	2014-10-29	云南烟草科学研究院	一种黄酮类化合物及其制备方法与应用
CN110615777A (zh) *	2019-08-19	2019-12-27	中国科学院长春应用化学研究所	化合物及其制备方法和应用
AR121719A1 (es)	2020-04-03	2022-06-29	Petra Pharma Corp	Inhibidores alostéricos de cromenona del fosfoinosítido 3-quinasa (pi3k) para el tratamiento de enfermedades
CN117693506A (zh) *	2021-05-03	2024-03-12	佩特拉制药公司	用于治疗疾病的磷酸肌醇3-激酶(pi3k)的变构色酮抑制剂
IL307950A (en) *	2021-05-03	2023-12-01	Petra Pharma Corp	Allosteric chromanone inhibitors of PHOSPHOINOSITIDE 3-KINASE (PI3K) for the treatment of diseases
MX2023013987A (es)	2021-05-27	2024-02-12	Petra Pharma Corp	Inhibidores alostéricos de cromenona de la fosfoinosítido 3-quinasa (pi3k) para el tratamiento contra el cáncer.
TW202329930A (zh)	2021-09-30	2023-08-01	美商佩特拉製藥公司	用於治療疾病之磷酸肌醇3-激酶(pi3k)之異位色烯酮抑制劑
FI4426434T3 (fi)	2021-11-02	2025-11-24	Flare Therapeutics Inc	Pparg:n käänteisagonisteja ja niiden käyttöjä
US20250263394A1 (en) *	2022-04-24	2025-08-21	InventisBio Co., Ltd.	Compounds, preparation methods and uses thereof
WO2024051778A1 (en) *	2022-09-09	2024-03-14	InventisBio Co., Ltd.	Compounds, preparation methods and uses thereof
WO2024097205A1 (en) *	2022-11-02	2024-05-10	Petra Pharma Corporation	Allosteric chromenone inhibitors of phosphoinositide 3-kinase (pi3k) for the treatment of disease
CN119874676A (zh) *	2023-10-25	2025-04-25	海创药业股份有限公司	一种pi3k抑制剂及其制备方法和用途

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE1270567B (de) *	1961-05-19	1968-06-20	Klinge Co Chem Pharm Fab	Verfahren zur Herstellung von basisch substituierten Flavonen
FR2516922A1 (fr) *	1981-11-25	1983-05-27	Lipha	Acides (oxo-4-4h-(1)-benzopyran-8-yl) alcanoiques, sels et derives, preparation et medicament les contenant
DE3311004A1 (de) *	1983-03-25	1984-09-27	Bayer Ag, 5090 Leverkusen	Chromon- und thiochromon-8-aldehyde, sowie ein verfahren zu ihrer herstellung
DE3517950A1 (de) *	1985-05-18	1986-11-20	Bayer Ag, 5090 Leverkusen	Verfahren zur herstellung von 2-thiochromenylidenacetessigestern
IL85554A0 (en) *	1987-03-02	1988-08-31	Takeda Chemical Industries Ltd	Chromone derivatives
US4889871A (en) *	1987-05-29	1989-12-26	G. D. Searle & Co.	Alkoxy-substituted dihydrobenzopyran-2-carboxylate derivatives

1989
- 1989-04-04 MA MA21775A patent/MA21528A1/fr unknown
- 1989-04-04 IL IL8984089A patent/IL89840A/en active IP Right Grant
- 1989-04-05 NZ NZ228625A patent/NZ228625A/en unknown
- 1989-04-05 SU SU894613889A patent/SU1739846A3/ru active
- 1989-04-05 IE IE108789A patent/IE62858B1/en not_active IP Right Cessation
- 1989-04-05 NO NO891415A patent/NO172344C/no unknown
- 1989-04-05 CA CA000595750A patent/CA1325205C/en not_active Expired - Fee Related
- 1989-04-05 ZA ZA892523A patent/ZA892523B/xx unknown
- 1989-04-06 PT PT90214A patent/PT90214B/pt not_active IP Right Cessation
- 1989-04-06 EP EP89400953A patent/EP0341104B1/en not_active Expired - Lifetime
- 1989-04-06 DK DK166789A patent/DK166789A/da not_active IP Right Cessation
- 1989-04-06 YU YU69289A patent/YU47308B/sh unknown
- 1989-04-06 AU AU32505/89A patent/AU630345B2/en not_active Ceased
- 1989-04-06 AT AT89400953T patent/ATE99302T1/de not_active IP Right Cessation
- 1989-04-06 ES ES89400953T patent/ES2060799T3/es not_active Expired - Lifetime
- 1989-04-06 DE DE89400953T patent/DE68911742T2/de not_active Expired - Fee Related
- 1989-04-06 HU HU891658A patent/HU206701B/hu unknown
- 1989-04-06 JP JP1087838A patent/JPH026473A/ja active Pending
- 1989-05-31 IN IN480/DEL/89A patent/IN170909B/en unknown
- 1989-08-06 OA OA59550A patent/OA09036A/xx unknown

Also Published As

Publication number	Publication date
IE62858B1 (en)	1995-03-08
IL89840A (en)	1996-10-31
EP0341104A3 (en)	1989-11-29
OA09036A (en)	1991-03-31
ATE99302T1 (de)	1994-01-15
HU206701B (en)	1992-12-28
HUT49600A (en)	1989-10-30
IN170909B (pt)	1992-06-13
NO172344B (no)	1993-03-29
SU1739846A3 (ru)	1992-06-07
DE68911742T2 (de)	1994-04-28
JPH026473A (ja)	1990-01-10
NO172344C (no)	1993-07-07
AU3250589A (en)	1989-10-12
DK166789A (da)	1989-10-07
DE68911742D1 (de)	1994-02-10
NZ228625A (en)	1992-03-26
EP0341104B1 (en)	1993-12-29
YU47308B (sh)	1995-01-31
YU69289A (en)	1991-06-30
CA1325205C (en)	1993-12-14
ES2060799T3 (es)	1994-12-01
ZA892523B (en)	1990-05-30
PT90214B (pt)	1994-07-29
EP0341104A2 (en)	1989-11-08
MA21528A1 (fr)	1989-12-31
AU630345B2 (en)	1992-10-29
IL89840A0 (en)	1989-12-15
NO891415L (no)	1989-10-09
DK166789D0 (da)	1989-04-06
NO891415D0 (no)	1989-04-05
IE891087L (en)	1989-10-06

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