PT91401A - Processo para a preparacao de compostos de benzodiazepina - Google Patents

Processo para a preparacao de compostos de benzodiazepina

Info

Publication number
PT91401A
PT91401A PT91401A PT9140189A PT91401A PT 91401 A PT91401 A PT 91401A PT 91401 A PT91401 A PT 91401A PT 9140189 A PT9140189 A PT 9140189A PT 91401 A PT91401 A PT 91401A
Authority
PT
Portugal
Prior art keywords
preparation
benzodiazepine compounds
benzodiazepine
compounds
Prior art date
Application number
PT91401A
Other languages
English (en)
Other versions
PT91401B (pt
Inventor
Jiban Kumar Chakrabarti
Terrence Michael Hotten
Original Assignee
Lilly Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Industries Ltd filed Critical Lilly Industries Ltd
Publication of PT91401A publication Critical patent/PT91401A/pt
Publication of PT91401B publication Critical patent/PT91401B/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/56—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurosurgery (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Neurology (AREA)
  • Public Health (AREA)
  • Anesthesiology (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
PT91401A 1988-08-11 1989-08-08 Processo para a preparacao de compostos de benzodiazepina PT91401B (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB888819059A GB8819059D0 (en) 1988-08-11 1988-08-11 Benzodiazepine compounds & their use as pharmaceuticals

Publications (2)

Publication Number Publication Date
PT91401A true PT91401A (pt) 1990-03-08
PT91401B PT91401B (pt) 1995-05-04

Family

ID=10641942

Family Applications (1)

Application Number Title Priority Date Filing Date
PT91401A PT91401B (pt) 1988-08-11 1989-08-08 Processo para a preparacao de compostos de benzodiazepina

Country Status (22)

Country Link
US (2) US4977150A (pt)
EP (1) EP0354781B1 (pt)
JP (1) JP2779219B2 (pt)
KR (1) KR0138527B1 (pt)
CN (1) CN1025857C (pt)
AR (1) AR246972A1 (pt)
AT (1) ATE113600T1 (pt)
AU (1) AU625067B2 (pt)
CA (1) CA1318669C (pt)
DE (1) DE68919154T2 (pt)
DK (1) DK393489A (pt)
ES (1) ES2062012T3 (pt)
GB (1) GB8819059D0 (pt)
HU (1) HU202239B (pt)
IE (1) IE64598B1 (pt)
IL (1) IL91246A (pt)
MX (1) MX17107A (pt)
NZ (1) NZ230251A (pt)
PH (1) PH27010A (pt)
PT (1) PT91401B (pt)
RU (1) RU2002752C1 (pt)
ZA (1) ZA896039B (pt)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE1004596A4 (fr) * 1990-09-26 1992-12-22 Therabel Res S A N V Derives de methylpiperazinoazepine, leur preparation et leur utilisation.
US5627178A (en) 1991-04-23 1997-05-06 Lilly Industries Limited 2-methyl-thieno-benzodiazepine
US5393752A (en) * 1992-05-26 1995-02-28 Therabel Research S.A./N.V. Methylpiperazinoazepine compounds, preparation and use thereof
US6034078A (en) * 1992-05-29 2000-03-07 Eli Lilly And Company Limited Thienobenzodiazepine compounds
US6617321B2 (en) * 1997-09-30 2003-09-09 Eli Lilly And Company 2-methyl-thieno-benzodiazepine formulation
CA2479932A1 (en) 2002-03-28 2003-10-09 Eli Lilly And Company Piperazine substituted aryl benzodiazepines and their use as dopamine receptor antagonists for the treatment of psychotic disorders
ATE361289T1 (de) * 2002-08-05 2007-05-15 Lilly Co Eli Piperazinsubstituierte arylbenzodiazepine
WO2005026177A1 (en) * 2003-09-09 2005-03-24 Eli Lilly And Company Substituted piperazines of azepines, oxazepines, and thiazepines
SI1838716T1 (sl) * 2005-01-05 2011-10-28 Lilly Co Eli Olanzapin pamoat dihidrat

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH468400A (de) * 1965-12-23 1969-02-15 Sandoz Ag Verfahren zur Herstellung neuer Thieno(2,3-b)(1,5)benzothiazepin-4-on-Verbindungen
US3539573A (en) * 1967-03-22 1970-11-10 Jean Schmutz 11-basic substituted dibenzodiazepines and dibenzothiazepines
US3758479A (en) * 1967-03-22 1973-09-11 Sandoz Ag Nitro and sulphamoyl substituted dibenzodiazepines
GB1292410A (en) * 1970-05-13 1972-10-11 Yoshitomi Pharmaceutical Thienobenzothiazepine derivatives
CH554362A (de) * 1970-07-30 1974-09-30 Spofa Vereinigte Pharma Werke Verfahren zur herstellung von neuen estern tricyklischer piperazinoalkanole.
US3897446A (en) * 1973-09-04 1975-07-29 Upjohn Co 6-Phenylthiazolo{8 3,2-a{9 {8 1,4{9 benzodiazepin-1-(2H)-ones, and processes
US4115568A (en) * 1974-11-26 1978-09-19 Lilly Industries Limited Thieno[3,2-b]-[1,5]benzodiazepines
SU629879A3 (ru) * 1974-11-26 1978-10-25 Лилли Индастриз Лимитед, (Фирма) Способ получени тиено(1,5) бензодиазепинов или их солей
US3951981A (en) * 1975-02-24 1976-04-20 American Cyanamid Company Substituted benzodiazepines and method of use
US4404137A (en) * 1979-10-16 1983-09-13 Lilly Industries Limited Pyrazolo [3,4-b][1,5]benzodiazepine compounds
US4431589A (en) * 1980-12-11 1984-02-14 Lilly House Benzodiazepine compounds and their use as pharmaceuticals

Also Published As

Publication number Publication date
IE892576L (en) 1990-02-11
HU202239B (en) 1991-02-28
JPH02104591A (ja) 1990-04-17
PT91401B (pt) 1995-05-04
AU625067B2 (en) 1992-07-02
AU3939989A (en) 1990-02-15
ES2062012T3 (es) 1994-12-16
KR0138527B1 (ko) 1998-05-15
EP0354781A3 (en) 1991-04-03
EP0354781A2 (en) 1990-02-14
ZA896039B (en) 1991-04-24
PH27010A (en) 1993-02-01
IE64598B1 (en) 1995-08-23
DK393489D0 (da) 1989-08-10
CN1040798A (zh) 1990-03-28
CA1318669C (en) 1993-06-01
US4977150A (en) 1990-12-11
DE68919154T2 (de) 1995-03-09
US5051516A (en) 1991-09-24
CN1025857C (zh) 1994-09-07
IL91246A (en) 1994-01-25
KR900003179A (ko) 1990-03-23
IL91246A0 (en) 1990-03-19
JP2779219B2 (ja) 1998-07-23
EP0354781B1 (en) 1994-11-02
DE68919154D1 (de) 1994-12-08
GB8819059D0 (en) 1988-09-14
HUT53109A (en) 1990-09-28
ATE113600T1 (de) 1994-11-15
RU2002752C1 (ru) 1993-11-15
MX17107A (es) 1993-08-01
AR246972A1 (es) 1994-10-31
DK393489A (da) 1990-02-12
NZ230251A (en) 1992-05-26

Similar Documents

Publication Publication Date Title
PT92534A (pt) Processo para a preparacao de compostos azabiciclicos
PT91440A (pt) Processo para a preparacao de agentes anti-fungicos de triazole
PT90619A (pt) Processo para a preparacao de compostos de piperazina
PT91068A (pt) Processo para a preparacao de compostos biarilo
PT90293A (pt) Processo para a preparacao de macrolidos
PT89264A (pt) Processo para a preparacao de compostos azabiciclicos
PT91664A (pt) Processo para a preparacao de compostos triciclicos derivados de benzodiazepina
PT91895A (pt) Processo para a preparacao de 9h-purinas substituidas
PT92786A (pt) Processo para a preparacao de compostos de tiazol
PT91872A (pt) Processo para a preparacao de compostos azabiciclicos
BR8906327A (pt) Processo para a preparacao de organoclorossilanos
PT90266A (pt) Processo para a preparacao de compostos azabiciclicos
PT92638A (pt) Processo para a preparacao de poliazamacrociclos mono-n-alquilados
PT90854A (pt) Processo para a preparacao de 1-aril-2-naftoilaminas
PT92365A (pt) Processo para a preparacao de (s)-alfa-etil-2-oxo-1-pirrolidinoacetamida
PT89775A (pt) Processo para a preparacao de derivados de isoquinolina
PT91401A (pt) Processo para a preparacao de compostos de benzodiazepina
BR8903367A (pt) Processo para a preparacao de organoclorossilanos
PT92507A (pt) Processo para a preparacao de alfa-ciano-beta-oxopropionamidas
BR8902030A (pt) Processo para a preparacao de n-fosfonometilglicina
PT94890A (pt) Processo para a preparacao de compostos azofenilicos
PT89954A (pt) Processo para a preparacao de pirroloquinolina-e pirrolofenotiazina-carboxamidas e de compostos afins
PT89237A (pt) Processo para a preparacao de compostos beta-lactamicos
PT94889A (pt) Processo para a preparacao de compostos azofenilicos
PT90267A (pt) Processo para a preparacao de compostos azabiciclicos

Legal Events

Date Code Title Description
FG3A Patent granted, date of granting

Effective date: 19941007

PD3A Change of proprietorship