PT916663E - 18beta, 19beta-diacetiloxi-18alfa, 19alfa-epoxi-3,13(16),14-clerodatrien-2-ona (esculenina a) e 18beta, 19beta-diacetiloxi-18alfa, 19alfa-epoxi-3,12,14-clerodatriemo-2beta-isovaleriloxi-16beta 7alfa-diol (esculentina b) um processo para a sua preparacao e sua utilizacao na producao de medicamentos - Google Patents

18beta, 19beta-diacetiloxi-18alfa, 19alfa-epoxi-3,13(16),14-clerodatrien-2-ona (esculenina a) e 18beta, 19beta-diacetiloxi-18alfa, 19alfa-epoxi-3,12,14-clerodatriemo-2beta-isovaleriloxi-16beta 7alfa-diol (esculentina b) um processo para a sua preparacao e sua utilizacao na producao de medicamentos

Info

Publication number
PT916663E
PT916663E PT98121657T PT98121657T PT916663E PT 916663 E PT916663 E PT 916663E PT 98121657 T PT98121657 T PT 98121657T PT 98121657 T PT98121657 T PT 98121657T PT 916663 E PT916663 E PT 916663E
Authority
PT
Portugal
Prior art keywords
epoxy
19beta
19alfa
18alfa
18beta
Prior art date
Application number
PT98121657T
Other languages
English (en)
Inventor
Swati Bal-Tembe
Erra Koteswara Sat Vijayakumar
Vijay Bhagwan Deore
Kalpana Sanjay Joshi
Original Assignee
Aventis Pharma Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aventis Pharma Gmbh filed Critical Aventis Pharma Gmbh
Publication of PT916663E publication Critical patent/PT916663E/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/94—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom spiro-condensed with carbocyclic rings or ring systems, e.g. griseofulvins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Rheumatology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Immunology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Furan Compounds (AREA)
  • Epoxy Compounds (AREA)
  • Steroid Compounds (AREA)
PT98121657T 1997-11-18 1998-11-12 18beta, 19beta-diacetiloxi-18alfa, 19alfa-epoxi-3,13(16),14-clerodatrien-2-ona (esculenina a) e 18beta, 19beta-diacetiloxi-18alfa, 19alfa-epoxi-3,12,14-clerodatriemo-2beta-isovaleriloxi-16beta 7alfa-diol (esculentina b) um processo para a sua preparacao e sua utilizacao na producao de medicamentos PT916663E (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP97120143 1997-11-18

Publications (1)

Publication Number Publication Date
PT916663E true PT916663E (pt) 2003-09-30

Family

ID=8227636

Family Applications (1)

Application Number Title Priority Date Filing Date
PT98121657T PT916663E (pt) 1997-11-18 1998-11-12 18beta, 19beta-diacetiloxi-18alfa, 19alfa-epoxi-3,13(16),14-clerodatrien-2-ona (esculenina a) e 18beta, 19beta-diacetiloxi-18alfa, 19alfa-epoxi-3,12,14-clerodatriemo-2beta-isovaleriloxi-16beta 7alfa-diol (esculentina b) um processo para a sua preparacao e sua utilizacao na producao de medicamentos

Country Status (8)

Country Link
US (1) US6107335A (pt)
EP (1) EP0916663B1 (pt)
JP (1) JP4373510B2 (pt)
AT (1) ATE239715T1 (pt)
DE (1) DE69814307T2 (pt)
DK (1) DK0916663T3 (pt)
ES (1) ES2198631T3 (pt)
PT (1) PT916663E (pt)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2575613C (en) * 2004-08-04 2015-05-19 Foam Supplies, Inc. Reactivity drift and catalyst degradation in polyurethane foam
CN104418829A (zh) * 2013-09-07 2015-03-18 山东大学（威海） 一种具有抗肿瘤作用的化合物单叶蔓荆素b的结构与制备方法及其用途
CN112239439A (zh) * 2019-07-17 2021-01-19 南开大学 四种具有抗癌活性的烈味脚骨脆二萜的制备方法和用途
IT201900018938A1 (it) 2019-10-16 2021-04-16 Univ Degli Studi Roma La Sapienza Uso di esculentina e suoi derivati per uso per il trattamento della fibrosi cistica

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5468772A (en) * 1993-03-10 1995-11-21 Pharmagenesis, Inc. Tripterinin compound and method

Also Published As

Publication number Publication date
DE69814307T2 (de) 2004-07-01
ES2198631T3 (es) 2004-02-01
EP0916663B1 (en) 2003-05-07
DE69814307D1 (de) 2003-06-12
US6107335A (en) 2000-08-22
ATE239715T1 (de) 2003-05-15
JPH11236383A (ja) 1999-08-31
JP4373510B2 (ja) 2009-11-25
EP0916663A1 (en) 1999-05-19
DK0916663T3 (da) 2003-07-28

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