PT923568E - Novas benzofuran-4-carboxamidas - Google Patents

Novas benzofuran-4-carboxamidas

Info

Publication number: PT923568E
Authority: PT; Portugal
Prior art keywords: carboxamides; new benzofuran; benzofuran; new; substituted
Prior art date: 1996-08-19

Application number

PT97942858T

Other languages

English (en)

Portuguese (pt)

Inventor

Hans-Peter Kley

Christian Schudt

Rolf Beume

Dietrich Hafner

Ulrich Thibaut

Wolf-Rudiger Ulrich

Dieter Flockerzi

Beate Schmidt

Armin Hatzelmann

Hermann Amschler

Original Assignee

Altana Pharma Ag

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1996-08-19

Filing date

1997-08-13

Publication date

2003-04-30

1997-08-13 Application filed by Altana Pharma Ag filed Critical Altana Pharma Ag

2003-04-30 Publication of PT923568E publication Critical patent/PT923568E/pt

Links

PIEXCQIOSMOEOU-UHFFFAOYSA-N 1-bromo-3-chloro-5,5-dimethylimidazolidine-2,4-dione Chemical group CC1(C)N(Br)C(=O)N(Cl)C1=O PIEXCQIOSMOEOU-UHFFFAOYSA-N 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
125000001449 isopropyl group Chemical group [H]C([H])([H])C([H])(*)C([H])([H])[H] 0.000 abstract 1
125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 1
125000004076 pyridyl group Chemical group 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
- C07D307/79—Benzo [b] furans; Hydrogenated benzo [b] furans with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Public Health (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Pharmacology & Pharmacy (AREA)
Veterinary Medicine (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Pulmonology (AREA)
Pain & Pain Management (AREA)
Rheumatology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Furan Compounds (AREA)
Table Devices Or Equipment (AREA)

PT97942858T 1996-08-19 1997-08-13 Novas benzofuran-4-carboxamidas PT923568E (pt)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
DE19633052		1996-08-19

Publications (1)

Publication Number	Publication Date
PT923568E true PT923568E (pt)	2003-04-30

Family

ID=7802799

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
PT97942858T PT923568E (pt)	1996-08-19	1997-08-13	Novas benzofuran-4-carboxamidas

Country Status (11)

Country	Link
US (1)	US6211203B1 (da)
EP (1)	EP0923568B9 (da)
JP (1)	JP4309475B2 (da)
AT (1)	ATE229516T1 (da)
AU (1)	AU4454597A (da)
CY (1)	CY2458B1 (da)
DE (1)	DE69717827T2 (da)
DK (1)	DK0923568T5 (da)
ES (1)	ES2188983T4 (da)
PT (1)	PT923568E (da)
WO (1)	WO1998007715A1 (da)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
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CN1219171A (zh) *	1996-05-20	1999-06-09	达尔文发现有限公司	苯并呋喃甲酰胺及其治疗用途
CA2317478A1 (en) *	1998-02-09	1999-08-12	Darwin Discovery Limited	Benzofuran-4-carboxamides and their therapeutic use
TW555759B (en) *	1998-06-08	2003-10-01	Darwin Discovery Ltd	Heterocyclic compounds and their therapeutic use
US6303789B1 (en) *	1998-06-10	2001-10-16	Byk Gulden Lomberg Chemische Fabrik Gmbh	Benzamides with tetrahydrofuranyloxy substitutents as phosphodiesterase 4 inhibitors
JP2002529444A (ja) *	1998-11-12	2002-09-10	アリアド・ファーマシューティカルズ・インコーポレイテッド	二環式シグナル伝達阻害剤、それを含む組成物とその用途
DE19924340A1 (de)	1999-05-27	2000-11-30	Basf Ag	Verfahren zur selektiven Hydrierung von ethylenisch ungesättigten Doppelbindungen in Polymeren
EP1212089B1 (en)	1999-08-21	2006-03-22	ALTANA Pharma AG	Synergistic combination of roflumilast and salmeterol
GB0003257D0 (en)	2000-02-11	2000-04-05	Darwin Discovery Ltd	Heterocyclic compounds and their therapeutic use
MXPA05010373A (es)	2003-04-01	2005-12-05	Applied Research Systems	Inhibidores de fosfodiesterasas en infertilidad.
EP1928437A2 (en)	2005-08-26	2008-06-11	Braincells, Inc.	Neurogenesis by muscarinic receptor modulation
EP2258358A3 (en)	2005-08-26	2011-09-07	Braincells, Inc.	Neurogenesis with acetylcholinesterase inhibitor
EP1940389A2 (en)	2005-10-21	2008-07-09	Braincells, Inc.	Modulation of neurogenesis by pde inhibition
US20070112017A1 (en)	2005-10-31	2007-05-17	Braincells, Inc.	Gaba receptor mediated modulation of neurogenesis
US20100216734A1 (en)	2006-03-08	2010-08-26	Braincells, Inc.	Modulation of neurogenesis by nootropic agents
US7842713B2 (en) *	2006-04-20	2010-11-30	Pfizer Inc	Fused phenyl amido heterocyclic compounds
AU2007249399A1 (en)	2006-05-09	2007-11-22	Braincells, Inc.	Neurogenesis by modulating angiotensin
WO2007134077A2 (en)	2006-05-09	2007-11-22	Braincells, Inc.	5 ht receptor mediated neurogenesis
EP2068872A1 (en)	2006-09-08	2009-06-17	Braincells, Inc.	Combinations containing a 4-acylaminopyridine derivative
US20100184806A1 (en)	2006-09-19	2010-07-22	Braincells, Inc.	Modulation of neurogenesis by ppar agents
KR101258331B1 (ko)	2008-09-11	2013-04-26	화이자 인코포레이티드	헤테로아릴 아미드 유도체 및 글루코키나제 활성화제로서의 그의 용도
AR074760A1 (es) *	2008-12-18	2011-02-09	Metabolex Inc	Agonistas del receptor gpr120 y usos de los mismos en medicamentos para el tratamiento de diabetes y el sindrome metabolico.
WO2010099217A1 (en)	2009-02-25	2010-09-02	Braincells, Inc.	Modulation of neurogenesis using d-cycloserine combinations
MY151246A (en) *	2009-03-11	2014-04-30	Pfizer	Benzofuranyl derivatives
RU2446143C2 (ru) *	2010-05-19	2012-03-27	Федеральное государственное бюджетное образовательное учреждение высшего профессионального образования "Ярославский государственный технический университет" (ЯГТУ)	Способ получения эфиров замещенных 5,6-дицианобензофуран-2-карбоновых кислот
US8299117B2 (en)	2010-06-16	2012-10-30	Metabolex Inc.	GPR120 receptor agonists and uses thereof
JP5746334B2 (ja) *	2010-06-16	2015-07-08	シマベイセラピューティクス，インコーポレーテッド	Ｇｐｒ１２０受容体作動薬及びその使用
WO2013106547A1 (en)	2012-01-10	2013-07-18	President And Fellows Of Harvard College	Beta-cell replication promoting compounds and methods of their use
CN111094279B (zh)	2017-11-10	2023-06-16	江苏恒瑞医药股份有限公司	一种苯并呋喃衍生物的制备方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
ES2176252T3 (es) *	1993-07-02	2002-12-01	Altana Pharma Ag	Benzamidas sustituidas con fluoro-alcoxi y su utilizacion como agentes inhibidores de fosfodiesterasas de nucleotidos ciclicos.
KR100381584B1 (ko) *	1994-07-22	2003-08-21	알타나 파마 아게	디히드로벤조푸란
ATE325110T1 (de) *	1995-05-19	2006-06-15	Kyowa Hakko Kogyo Kk	Sauerstoff enthaltende heterocyclische verbindungen
KR19990071894A (ko) *	1995-12-05	1999-09-27	마르크 젠너	벤조퓨란 카르복사미드 및 술폰아미드
CN1219171A (zh) *	1996-05-20	1999-06-09	达尔文发现有限公司	苯并呋喃甲酰胺及其治疗用途

1997
- 1997-08-13 WO PCT/EP1997/004398 patent/WO1998007715A1/en not_active Ceased
- 1997-08-13 AT AT97942858T patent/ATE229516T1/de not_active IP Right Cessation
- 1997-08-13 DE DE69717827T patent/DE69717827T2/de not_active Expired - Lifetime
- 1997-08-13 AU AU44545/97A patent/AU4454597A/en not_active Abandoned
- 1997-08-13 DK DK97942858T patent/DK0923568T5/da active
- 1997-08-13 JP JP51035698A patent/JP4309475B2/ja not_active Expired - Fee Related
- 1997-08-13 PT PT97942858T patent/PT923568E/pt unknown
- 1997-08-13 US US09/147,640 patent/US6211203B1/en not_active Expired - Lifetime
- 1997-08-13 EP EP97942858A patent/EP0923568B9/en not_active Expired - Lifetime
- 1997-08-13 ES ES97942858T patent/ES2188983T4/es not_active Expired - Lifetime
2004
- 2004-06-08 CY CY0400046A patent/CY2458B1/xx unknown

Also Published As

Publication number	Publication date
DK0923568T3 (da)	2003-04-07
US6211203B1 (en)	2001-04-03
EP0923568B9 (en)	2003-08-13
ES2188983T4 (es)	2004-06-01
JP2000516932A (ja)	2000-12-19
DK0923568T5 (da)	2003-11-03
ATE229516T1 (de)	2002-12-15
DE69717827T2 (de)	2003-09-04
WO1998007715A9 (en)	1999-04-29
DE69717827D1 (de)	2003-01-23
CY2458B1 (en)	2005-06-03
WO1998007715A1 (en)	1998-02-26
EP0923568B1 (en)	2002-12-11
EP0923568A1 (en)	1999-06-23
AU4454597A (en)	1998-03-06
JP4309475B2 (ja)	2009-08-05
ES2188983T3 (es)	2003-07-01

Publication	Publication Date	Title
PT923568E (pt)	2003-04-30	Novas benzofuran-4-carboxamidas
EA199700061A1 (ru)	1997-12-30	Способ получения силденафила
ATE211139T1 (de)	2002-01-15	Tetrahydroimidazopyridoindoldione als cgmp spezifische pde hemmer
ES2193252T3 (es)	2003-11-01	Quinolonas y su uso terapeutico.
ATE260103T1 (de)	2004-03-15	Ortho-anthranilamide derivate als antikoagulantien
MX9700557A (es)	1997-12-31	Dihidrobenzofuranos.
FI974180A0 (fi)	1997-11-10	Spirosyklisiä ja bisyklisiä diatsinyyli- ja karbatsinyylioksatsolidinoneja
MX9205678A (es)	1993-04-01	Heteroarilaminas como nuevos inhibidores de la acetilcolinesterasa.
DK0923554T3 (da)	2002-04-29	N-Benzylpiperidin- og tetrahydropyridinderivater
EP0932606A4 (en)	2000-01-19	Inhibitors of prenyl transferases
DE69719358D1 (de)	2003-04-03	Substituierte dihydrobenzofurane als pde-hemmstoffe
DE69722656D1 (de)	2003-07-10	Bicyclische arylcarboxamide und ihre therapeutische verwendung
DE59100597D1 (de)	1993-12-23	Verwendung von N-Alkyl-lactamen als Kristallisationsinhibitoren.
ES2071325T3 (es)	1995-06-16	Derivados de 4-alquilimidazol.
DK0696278T3 (da)	1999-04-26	Herbicidtvirkende substituerede 1-phenyl- eller 1-pyridinylbenzotriazoler
ATE219481T1 (de)	2002-07-15	1,7,7-trimethyl-bicyclo(2.2.1)heptane derivative
ES2179254T3 (es)	2003-01-16	1-poliarilpirazoles plaguicidas.
ES2173634T3 (es)	2002-10-16	Compuestos heterociclicos que presentan actividad inhibidora de mmp y tnf.
ATE135352T1 (de)	1996-03-15	3-keto-hmg-coa reduktase-inhibitoren
SU1690242A1 (ru)	1999-08-10	Антифидант
UY24326A1 (es)	2000-12-29	Nuevas piperidinas.
NO994997D0 (no)	1999-10-14	Alkaloidhalidsalter av swainsonin og fremgangsmåter ved anvendelse