|
EP0368684B2
(en)
|
1988-11-11 |
2004-09-29 |
Medical Research Council |
Cloning immunoglobulin variable domain sequences.
|
|
US6291159B1
(en)
*
|
1989-05-16 |
2001-09-18 |
Scripps Research Institute |
Method for producing polymers having a preselected activity
|
|
US6969586B1
(en)
|
1989-05-16 |
2005-11-29 |
Scripps Research Institute |
Method for tapping the immunological repertoire
|
|
US6291160B1
(en)
*
|
1989-05-16 |
2001-09-18 |
Scripps Research Institute |
Method for producing polymers having a preselected activity
|
|
US6680192B1
(en)
|
1989-05-16 |
2004-01-20 |
Scripps Research Institute |
Method for producing polymers having a preselected activity
|
|
US6291158B1
(en)
|
1989-05-16 |
2001-09-18 |
Scripps Research Institute |
Method for tapping the immunological repertoire
|
|
US6291161B1
(en)
|
1989-05-16 |
2001-09-18 |
Scripps Research Institute |
Method for tapping the immunological repertiore
|
|
ES2225816T5
(es)
|
1990-02-01 |
2014-08-21 |
Siemens Healthcare Diagnostics Products Gmbh |
Producción y utilización de bancos de genes de anticuerpos humanos ("bibliotecas de anticuerpos humanos")
|
|
US5747334A
(en)
*
|
1990-02-15 |
1998-05-05 |
The University Of North Carolina At Chapel Hill |
Random peptide library
|
|
US5498538A
(en)
*
|
1990-02-15 |
1996-03-12 |
The University Of North Carolina At Chapel Hill |
Totally synthetic affinity reagents
|
|
US5427908A
(en)
*
|
1990-05-01 |
1995-06-27 |
Affymax Technologies N.V. |
Recombinant library screening methods
|
|
US5723286A
(en)
|
1990-06-20 |
1998-03-03 |
Affymax Technologies N.V. |
Peptide library and screening systems
|
|
US6916605B1
(en)
|
1990-07-10 |
2005-07-12 |
Medical Research Council |
Methods for producing members of specific binding pairs
|
|
GB9206318D0
(en)
*
|
1992-03-24 |
1992-05-06 |
Cambridge Antibody Tech |
Binding substances
|
|
GB9015198D0
(en)
*
|
1990-07-10 |
1990-08-29 |
Brien Caroline J O |
Binding substance
|
|
US6172197B1
(en)
|
1991-07-10 |
2001-01-09 |
Medical Research Council |
Methods for producing members of specific binding pairs
|
|
US7063943B1
(en)
|
1990-07-10 |
2006-06-20 |
Cambridge Antibody Technology |
Methods for producing members of specific binding pairs
|
|
IL99552A0
(en)
*
|
1990-09-28 |
1992-08-18 |
Ixsys Inc |
Compositions containing procaryotic cells,a kit for the preparation of vectors useful for the coexpression of two or more dna sequences and methods for the use thereof
|
|
WO1992015678A1
(en)
*
|
1991-03-01 |
1992-09-17 |
Stratagene |
Pcr generated dicistronic dna molecules for producing antibodies
|
|
US6492160B1
(en)
|
1991-05-15 |
2002-12-10 |
Cambridge Antibody Technology Limited |
Methods for producing members of specific binding pairs
|
|
US6225447B1
(en)
|
1991-05-15 |
2001-05-01 |
Cambridge Antibody Technology Ltd. |
Methods for producing members of specific binding pairs
|
|
DE69230142T2
(de)
|
1991-05-15 |
2000-03-09 |
Cambridge Antibody Technology Ltd. |
Verfahren zur herstellung von spezifischen bindungspaargliedern
|
|
US5858657A
(en)
*
|
1992-05-15 |
1999-01-12 |
Medical Research Council |
Methods for producing members of specific binding pairs
|
|
US5962255A
(en)
*
|
1992-03-24 |
1999-10-05 |
Cambridge Antibody Technology Limited |
Methods for producing recombinant vectors
|
|
US5270170A
(en)
*
|
1991-10-16 |
1993-12-14 |
Affymax Technologies N.V. |
Peptide library and screening method
|
|
US5733731A
(en)
*
|
1991-10-16 |
1998-03-31 |
Affymax Technologies N.V. |
Peptide library and screening method
|
|
US5872215A
(en)
*
|
1991-12-02 |
1999-02-16 |
Medical Research Council |
Specific binding members, materials and methods
|
|
DE69233408T2
(de)
*
|
1991-12-02 |
2005-09-22 |
Cambridge Antibody Technology Ltd., Melbourn |
Herstellung von Antikörpern auf Phagenoberflächen ausgehend von Antikörpersegmentbibliotheken.
|
|
DK1696031T3
(da)
*
|
1991-12-02 |
2010-08-02 |
Medimmune Ltd |
Fremstilling af anti-autoantigener fra antistofsegmentrepertoirer og præsentere på fag
|
|
PT1024191E
(pt)
|
1991-12-02 |
2008-12-22 |
Medical Res Council |
Produção de auto-anticorpos a partir de reportórios de segmentos de anticorpo e exibidos em fagos
|
|
US5733743A
(en)
*
|
1992-03-24 |
1998-03-31 |
Cambridge Antibody Technology Limited |
Methods for producing members of specific binding pairs
|
|
US5605793A
(en)
|
1994-02-17 |
1997-02-25 |
Affymax Technologies N.V. |
Methods for in vitro recombination
|
|
US6309883B1
(en)
|
1994-02-17 |
2001-10-30 |
Maxygen, Inc. |
Methods and compositions for cellular and metabolic engineering
|
|
US5837458A
(en)
|
1994-02-17 |
1998-11-17 |
Maxygen, Inc. |
Methods and compositions for cellular and metabolic engineering
|
|
US6165793A
(en)
*
|
1996-03-25 |
2000-12-26 |
Maxygen, Inc. |
Methods for generating polynucleotides having desired characteristics by iterative selection and recombination
|
|
US6995017B1
(en)
|
1994-02-17 |
2006-02-07 |
Maxygen, Inc. |
Methods for generating polynucleotides having desired characteristics by iterative selection and recombination
|
|
US6117679A
(en)
|
1994-02-17 |
2000-09-12 |
Maxygen, Inc. |
Methods for generating polynucleotides having desired characteristics by iterative selection and recombination
|
|
US6335160B1
(en)
|
1995-02-17 |
2002-01-01 |
Maxygen, Inc. |
Methods and compositions for polypeptide engineering
|
|
US20060257890A1
(en)
*
|
1996-05-20 |
2006-11-16 |
Maxygen, Inc. |
Methods and compositions for cellular and metabolic engineering
|
|
PT699237E
(pt)
*
|
1994-03-17 |
2003-07-31 |
Merck Patent Gmbh |
Fvs de cadeia anti-egfr e anticorpos anti-egfr
|
|
EP0759976A4
(en)
*
|
1994-03-30 |
2001-02-07 |
Igen Int Inc |
The isolation and production of catalytic antibodies using phage technology
|
|
DE69535557T2
(de)
|
1994-12-30 |
2008-04-30 |
Planet Biotechnology, Inc., San Diego |
Verfahren zur herstellung von schutzproteine enthaltende immunoglobuline und ihre verwendung
|
|
US6808709B1
(en)
|
1994-12-30 |
2004-10-26 |
The Regents Of The University Of California |
Immunoglobulins containing protection proteins and their use
|
|
US6046037A
(en)
*
|
1994-12-30 |
2000-04-04 |
Hiatt; Andrew C. |
Method for producing immunoglobulins containing protection proteins in plants and their use
|
|
AUPO591797A0
(en)
|
1997-03-27 |
1997-04-24 |
Commonwealth Scientific And Industrial Research Organisation |
High avidity polyvalent and polyspecific reagents
|
|
WO1997002479A2
(en)
*
|
1995-06-30 |
1997-01-23 |
Yale University |
Human monoclonal anti-tumor antibodies
|
|
US7368111B2
(en)
|
1995-10-06 |
2008-05-06 |
Cambridge Antibody Technology Limited |
Human antibodies specific for TGFβ2
|
|
US6153410A
(en)
*
|
1997-03-25 |
2000-11-28 |
California Institute Of Technology |
Recombination of polynucleotide sequences using random or defined primers
|
|
GB9712512D0
(en)
|
1997-06-16 |
1997-08-20 |
Bioinvent Int Ab |
A method for in vitro molecular evolution of protein function
|
|
US6537746B2
(en)
|
1997-12-08 |
2003-03-25 |
Maxygen, Inc. |
Method for creating polynucleotide and polypeptide sequences
|
|
ES2299244T3
(es)
|
1998-05-13 |
2008-05-16 |
Domantis Limited |
Sistema de exposicion de fagos para la seleccion de proteinas correctamente plegadas.
|
|
US7153655B2
(en)
|
1998-06-16 |
2006-12-26 |
Alligator Bioscience Ab |
Method for in vitro molecular evolution of protein function involving the use of exonuclease enzyme and two populations of parent polynucleotide sequence
|
|
US6365408B1
(en)
|
1998-06-19 |
2002-04-02 |
Maxygen, Inc. |
Methods of evolving a polynucleotides by mutagenesis and recombination
|
|
US8609614B2
(en)
|
1998-07-22 |
2013-12-17 |
Vanderbilt University |
GBS toxin receptor compositions and methods of use
|
|
US6492497B1
(en)
|
1999-04-30 |
2002-12-10 |
Cambridge Antibody Technology Limited |
Specific binding members for TGFbeta1
|
|
US6924359B1
(en)
|
1999-07-01 |
2005-08-02 |
Yale University |
Neovascular-targeted immunoconjugates
|
|
CA2369050A1
(en)
|
2000-02-02 |
2001-08-09 |
Vanderbilt University |
Methods for preventing or attenuating pathoangiogenic conditions
|
|
WO2001062907A1
(fr)
|
2000-02-22 |
2001-08-30 |
Medical & Biological Laboratories Co., Ltd. |
Bibliotheque d'anticorps
|
|
CA2407426A1
(en)
|
2000-04-28 |
2001-11-08 |
Planet Biotechnology, Inc. |
Immunoadhesin for the prevention of rhinovirus infection
|
|
US6902734B2
(en)
|
2000-08-07 |
2005-06-07 |
Centocor, Inc. |
Anti-IL-12 antibodies and compositions thereof
|
|
US7288390B2
(en)
|
2000-08-07 |
2007-10-30 |
Centocor, Inc. |
Anti-dual integrin antibodies, compositions, methods and uses
|
|
UA81743C2
(uk)
|
2000-08-07 |
2008-02-11 |
Центокор, Инк. |
МОНОКЛОНАЛЬНЕ АНТИТІЛО ЛЮДИНИ, ЩО СПЕЦИФІЧНО ЗВ'ЯЗУЄТЬСЯ З ФАКТОРОМ НЕКРОЗУ ПУХЛИН АЛЬФА (ФНПα), ФАРМАЦЕВТИЧНА КОМПОЗИЦІЯ, ЩО ЙОГО МІСТИТЬ, ТА СПОСІБ ЛІКУВАННЯ РЕВМАТОЇДНОГО АРТРИТУ
|
|
AU2001297872B2
(en)
|
2000-11-17 |
2006-11-09 |
University Of Rochester |
In vitro methods of producing and identifying immunoglobulin molecules in eukaryotic cells
|
|
WO2002048401A2
(en)
|
2000-12-11 |
2002-06-20 |
Alexion Pharmaceuticals, Inc. |
Nested oligonucleotides containing hairpin for nucleic acid amplification
|
|
US6958213B2
(en)
|
2000-12-12 |
2005-10-25 |
Alligator Bioscience Ab |
Method for in vitro molecular evolution of protein function
|
|
US20020086292A1
(en)
|
2000-12-22 |
2002-07-04 |
Shigeaki Harayama |
Synthesis of hybrid polynucleotide molecules using single-stranded polynucleotide molecules
|
|
US7981420B2
(en)
|
2000-12-22 |
2011-07-19 |
Max-Planck-Gesellschaft Zur Foederung Der Wissenschaften E.V. |
Therapeutic use of antibodies directed against repulsive guidance molecule (RGM)
|
|
PT2308888T
(pt)
|
2001-11-14 |
2017-05-03 |
Janssen Biotech Inc |
Anticorpos anti-il-6, composições, métodos e utilizações
|
|
SI2508596T1
(sl)
|
2002-02-21 |
2016-01-29 |
Institute Of Virology Slovak Academy Of Sciences |
Monoklonska protitelesa, specifična za MN/CA IX, proizvedena iz MN/CA IX deficientnih miši, in postopki uporabe
|
|
DK1504098T4
(da)
|
2002-05-17 |
2011-05-23 |
Alligator Bioscience Ab |
Fremgangsmåde til molekyulær udvikling in vitro af proteinfunktion
|
|
US9028822B2
(en)
|
2002-06-28 |
2015-05-12 |
Domantis Limited |
Antagonists against TNFR1 and methods of use therefor
|
|
US9321832B2
(en)
|
2002-06-28 |
2016-04-26 |
Domantis Limited |
Ligand
|
|
US7696320B2
(en)
|
2004-08-24 |
2010-04-13 |
Domantis Limited |
Ligands that have binding specificity for VEGF and/or EGFR and methods of use therefor
|
|
DE10303974A1
(de)
|
2003-01-31 |
2004-08-05 |
Abbott Gmbh & Co. Kg |
Amyloid-β(1-42)-Oligomere, Verfahren zu deren Herstellung und deren Verwendung
|
|
US9708410B2
(en)
|
2003-05-30 |
2017-07-18 |
Janssen Biotech, Inc. |
Anti-tissue factor antibodies and compositions
|
|
TW200607523A
(en)
|
2004-06-01 |
2006-03-01 |
Domantis Ltd |
Drug compositions, fusions and conjugates
|
|
US7563443B2
(en)
|
2004-09-17 |
2009-07-21 |
Domantis Limited |
Monovalent anti-CD40L antibody polypeptides and compositions thereof
|
|
GB0521621D0
(en)
|
2005-10-24 |
2005-11-30 |
Domantis Ltd |
Tumor necrosis factor receptor 1 antagonists for treating respiratory diseases
|
|
JO3058B1
(ar)
|
2005-04-29 |
2017-03-15 |
Applied Molecular Evolution Inc |
الاجسام المضادة لمضادات -اي ال-6,تركيباتها طرقها واستعمالاتها
|
|
CN103145842A
(zh)
|
2005-06-30 |
2013-06-12 |
Abbvie公司 |
Il-12/p40结合蛋白
|
|
SI2452694T1
(sl)
|
2005-06-30 |
2019-05-31 |
Janssen Biotech, Inc. |
Protitelesa proti-IL-23, sestavki in postopki uporabe
|
|
US7612181B2
(en)
|
2005-08-19 |
2009-11-03 |
Abbott Laboratories |
Dual variable domain immunoglobulin and uses thereof
|
|
NZ612578A
(en)
|
2005-08-19 |
2014-11-28 |
Abbvie Inc |
Dual variable domain immunoglobin and uses thereof
|
|
EP2500355A3
(en)
|
2005-08-19 |
2012-10-24 |
Abbott Laboratories |
Dual variable domain immunoglobulin and uses thereof
|
|
EP1928905B1
(de)
|
2005-09-30 |
2015-04-15 |
AbbVie Deutschland GmbH & Co KG |
Bindungsdomänen von proteinen der repulsive guidance molecule (rgm) proteinfamilie und funktionale fragmente davon sowie deren verwendung
|
|
HRP20140240T4
(hr)
|
2005-11-30 |
2017-02-24 |
Abbvie Inc. |
Monoklonalna antitijela protiv amiloidnih beta proteina i njihova upotreba
|
|
US8691224B2
(en)
|
2005-11-30 |
2014-04-08 |
Abbvie Inc. |
Anti-Aβ globulomer 5F7 antibodies
|
|
HUE034269T2
(en)
|
2005-12-29 |
2018-02-28 |
Janssen Biotech Inc |
Human anti-IL-23 antibodies, preparations, methods and applications
|
|
JP2010502224A
(ja)
|
2006-09-08 |
2010-01-28 |
アボット・ラボラトリーズ |
インターロイキン13結合タンパク質
|
|
US8455626B2
(en)
|
2006-11-30 |
2013-06-04 |
Abbott Laboratories |
Aβ conformer selective anti-aβ globulomer monoclonal antibodies
|
|
US8895004B2
(en)
|
2007-02-27 |
2014-11-25 |
AbbVie Deutschland GmbH & Co. KG |
Method for the treatment of amyloidoses
|
|
CA2688433A1
(en)
|
2007-06-06 |
2008-12-11 |
Domantis Limited |
Methods for selecting protease resistant polypeptides
|
|
GB0724331D0
(en)
|
2007-12-13 |
2008-01-23 |
Domantis Ltd |
Compositions for pulmonary delivery
|
|
EP2214708A4
(en)
|
2007-10-26 |
2011-01-12 |
Centocor Ortho Biotech Inc |
VECTORS, HOST CELLS, METHODS OF PRODUCTION AND USES
|
|
US8962803B2
(en)
|
2008-02-29 |
2015-02-24 |
AbbVie Deutschland GmbH & Co. KG |
Antibodies against the RGM A protein and uses thereof
|
|
SG190572A1
(en)
|
2008-04-29 |
2013-06-28 |
Abbott Lab |
Dual variable domain immunoglobulins and uses thereof
|
|
EP2116556B1
(en)
|
2008-05-09 |
2016-03-23 |
AbbVie Deutschland GmbH & Co KG |
Antibodies to receptor of advanced glycation end products (RAGE) and uses thereof
|
|
TW201006485A
(en)
|
2008-06-03 |
2010-02-16 |
Abbott Lab |
Dual variable domain immunoglobulins and uses thereof
|
|
CA2726087A1
(en)
|
2008-06-03 |
2009-12-10 |
Tariq Ghayur |
Dual variable domain immunoglobulins and uses thereof
|
|
EP2650014A2
(en)
|
2008-06-20 |
2013-10-16 |
Wyeth LLC |
Compositions and methods of use of ORF1358 from beta-hemolytic streptococcal strains
|
|
CN102149825B
(zh)
|
2008-07-08 |
2015-07-22 |
Abbvie公司 |
前列腺素e2双重可变结构域免疫球蛋白及其用途
|
|
TW201014602A
(en)
|
2008-07-08 |
2010-04-16 |
Abbott Lab |
Prostaglandin E2 binding proteins and uses thereof
|
|
KR20160116056A
(ko)
|
2008-08-14 |
2016-10-06 |
테바 파마슈티컬즈 오스트레일리아 피티와이 엘티디 |
항-il-12/il-23 항체
|
|
EP2391652A4
(en)
|
2009-01-29 |
2013-01-02 |
Abbott Lab |
IL-1 BINDING PROTEINS
|
|
US8030026B2
(en)
|
2009-02-24 |
2011-10-04 |
Abbott Laboratories |
Antibodies to troponin I and methods of use thereof
|
|
TWI541021B
(zh)
|
2009-03-05 |
2016-07-11 |
艾伯維有限公司 |
Il-17結合蛋白
|
|
CN102459591B
(zh)
|
2009-05-20 |
2015-05-13 |
诺维莫尼公司 |
合成性的多肽文库以及用于建立具有天然多样性的多肽变体的方法
|
|
CA2758356C
(en)
|
2009-05-29 |
2016-07-26 |
Morphosys Ag |
A collection of vh and vl pairs having favourable biophysical properties and methods for its use
|
|
BR112012004546A8
(pt)
|
2009-08-29 |
2017-12-05 |
Abbott Lab |
Terapêutica por proteínas ligantes dll4-ligantes
|
|
WO2011028811A2
(en)
|
2009-09-01 |
2011-03-10 |
Abbott Laboratories |
Dual variable domain immunoglobulins and uses thereof
|
|
BR112012008833A2
(pt)
|
2009-10-15 |
2015-09-08 |
Abbott Lab |
imunoglobulinas de dominio variavel duplo e usos das mesmas
|
|
UY32979A
(es)
|
2009-10-28 |
2011-02-28 |
Abbott Lab |
Inmunoglobulinas con dominio variable dual y usos de las mismas
|
|
WO2011053707A1
(en)
|
2009-10-31 |
2011-05-05 |
Abbott Laboratories |
Antibodies to receptor for advanced glycation end products (rage) and uses thereof
|
|
US20110165648A1
(en)
|
2009-11-04 |
2011-07-07 |
Menno Van Lookeren Campagne |
Co-crystal structure of factor D and anti-factor D antibody
|
|
MX2012006560A
(es)
|
2009-12-08 |
2012-10-05 |
Abbott Gmbh & Co Kg |
Anticuerpos monoclonales contra la proteina rgm a para utilizarse en el tratamiento de degeneracion de capa de fibra de nervio retinal.
|
|
KR20130009760A
(ko)
|
2010-02-10 |
2013-01-23 |
이뮤노젠 아이엔씨 |
Cd20 항체 및 이의 용도
|
|
TWI622402B
(zh)
|
2010-02-24 |
2018-05-01 |
免疫遺傳股份有限公司 |
葉酸受體1抗體類和免疫共軛物類及彼等之用途
|
|
KR101853278B1
(ko)
|
2010-03-02 |
2018-05-02 |
애브비 인코포레이티드 |
치료학적 dll4 결합 단백질
|
|
HUE036157T2
(hu)
|
2010-03-30 |
2018-06-28 |
Janssen Biotech Inc |
Humanizált IL-25 ellenanyagok
|
|
US8987419B2
(en)
|
2010-04-15 |
2015-03-24 |
AbbVie Deutschland GmbH & Co. KG |
Amyloid-beta binding proteins
|
|
AR081246A1
(es)
|
2010-05-14 |
2012-07-18 |
Abbott Lab |
Proteinas de union a il-1
|
|
WO2012006500A2
(en)
|
2010-07-08 |
2012-01-12 |
Abbott Laboratories |
Monoclonal antibodies against hepatitis c virus core protein
|
|
UY33492A
(es)
|
2010-07-09 |
2012-01-31 |
Abbott Lab |
Inmunoglobulinas con dominio variable dual y usos de las mismas
|
|
EP3252072A3
(en)
|
2010-08-03 |
2018-03-14 |
AbbVie Inc. |
Dual variable domain immunoglobulins and uses thereof
|
|
EP3533803B1
(en)
|
2010-08-14 |
2021-10-27 |
AbbVie Inc. |
Anti-amyloid-beta antibodies
|
|
WO2012024650A2
(en)
|
2010-08-19 |
2012-02-23 |
Abbott Laboratories |
Anti-ngf antibodies and their use
|
|
JP2013539364A
(ja)
|
2010-08-26 |
2013-10-24 |
アッヴィ・インコーポレイテッド |
二重可変ドメイン免疫グロブリンおよびその使用
|
|
US8367586B2
(en)
|
2010-11-19 |
2013-02-05 |
Morphosys Ag |
Collection and methods for its use
|
|
TW201307388A
(zh)
|
2010-12-21 |
2013-02-16 |
Abbott Lab |
Il-1結合蛋白
|
|
PE20141060A1
(es)
|
2010-12-21 |
2014-09-26 |
Abbvie Inc |
Inmunoglobulinas de dominio variable dual biespecificas de il-1 alfa y beta y su uso
|
|
CN103620032B
(zh)
|
2010-12-31 |
2016-02-24 |
生物蛋白有限公司 |
抗体的快速人源化
|
|
SG10201805064SA
(en)
|
2011-06-23 |
2018-07-30 |
Ablynx Nv |
Techniques for predicting, detecting and reducing aspecific protein interference in assays involving immunoglobulin single variable domains
|
|
EP4350345A3
(en)
|
2011-06-23 |
2024-07-24 |
Ablynx N.V. |
Techniques for predicting, detecting and reducing aspecific protein interference in assays involving immunoglobin single variable domains
|
|
RS55775B2
(sr)
|
2011-06-23 |
2022-10-31 |
Ablynx Nv |
Tehnike za predviđanje, otkrivanje i smanjenje nespecifične proteinske interferencije u testovima koji uključuju pojedinačne varijabilne domene imunoglobulina
|
|
SG10201505454SA
(en)
|
2011-07-13 |
2015-09-29 |
Abbvie Inc |
Methods and compositions for treating asthma using anti-il-13 antibodies
|
|
HK1200322A1
(en)
|
2011-10-24 |
2015-08-07 |
Abbvie Inc. |
Immunobinders directed against sclerostin
|
|
DK2797957T3
(da)
|
2011-11-23 |
2019-09-23 |
Medimmune Llc |
Bindingsmolekyler specifikke for her3 og anvendelser deraf
|
|
TW201333035A
(zh)
|
2011-12-30 |
2013-08-16 |
Abbvie Inc |
針對il-13及/或il-17之雙特異性結合蛋白
|
|
EP3369746A1
(en)
|
2012-01-27 |
2018-09-05 |
AbbVie Deutschland GmbH & Co KG |
Composition and method for diagnosis and treatment of diseases associated with neurite degeneration
|
|
AU2013229786B2
(en)
|
2012-03-08 |
2017-06-22 |
Halozyme, Inc. |
Conditionally active anti-epidermal growth factor receptor antibodies and methods of use thereof
|
|
UY34905A
(es)
|
2012-07-12 |
2014-01-31 |
Abbvie Inc |
Proteínas de unión a il-1
|
|
US9200073B2
(en)
|
2012-08-31 |
2015-12-01 |
Immunogen, Inc. |
Diagnostic assays and kits for detection of folate receptor 1
|
|
TW202037609A
(zh)
|
2012-11-01 |
2020-10-16 |
美商艾伯維有限公司 |
抗-vegf/dll4雙重可變區域免疫球蛋白及其用途
|
|
US9550986B2
(en)
|
2012-12-21 |
2017-01-24 |
Abbvie Inc. |
High-throughput antibody humanization
|
|
WO2014113431A2
(en)
*
|
2013-01-15 |
2014-07-24 |
Tufts Medical Center |
Methods and compositions for targeting immunoglobulins
|
|
MX362075B
(es)
|
2013-03-14 |
2019-01-07 |
Abbott Lab |
Ensayo de combinación de antígeno-anticuerpo del virus de la hepatitis c (vhc) y métodos y composiciones para usarlo.
|
|
WO2014143343A1
(en)
|
2013-03-14 |
2014-09-18 |
Abbott Laboratories |
Hcv core lipid binding domain monoclonal antibodies
|
|
JP2016512241A
(ja)
|
2013-03-14 |
2016-04-25 |
アボット・ラボラトリーズAbbott Laboratories |
改良された抗体検出のためのhcvns3組換え抗原およびこの突然変異体
|
|
WO2014144280A2
(en)
|
2013-03-15 |
2014-09-18 |
Abbvie Inc. |
DUAL SPECIFIC BINDING PROTEINS DIRECTED AGAINST IL-1β AND / OR IL-17
|
|
CN113150145B
(zh)
|
2013-08-30 |
2025-02-14 |
伊缪诺金公司 |
用于检测叶酸受体1的抗体和测定
|
|
JP6282745B2
(ja)
|
2013-09-12 |
2018-02-21 |
ハロザイム インコーポレイテッド |
修飾抗上皮成長因子受容体抗体およびその使用法
|
|
WO2015097536A2
(en)
|
2013-12-24 |
2015-07-02 |
Janssen Pharmaceutical Nv |
Anti-vista antibodies and fragments
|
|
AU2015244025B2
(en)
|
2014-04-08 |
2019-03-21 |
Boston Pharmaceuticals Inc. |
Binding molecules specific for IL-21 and uses thereof
|
|
SG11201608192SA
(en)
|
2014-04-11 |
2016-10-28 |
Medimmune Llc |
Bispecific her2 antibodies
|
|
GB201406767D0
(en)
|
2014-04-15 |
2014-05-28 |
Cancer Rec Tech Ltd |
Humanized anti-Tn-MUC1 antibodies anf their conjugates
|
|
GB2537445A
(en)
|
2014-11-10 |
2016-10-19 |
Medimmune Ltd |
Binding molecules specific for CD73 and uses thereof
|
|
GB2538120A
(en)
|
2014-11-11 |
2016-11-09 |
Medimmune Ltd |
Therapeutic combinations comprising anti-CD73 antibodies and uses thereof
|
|
US10093733B2
(en)
|
2014-12-11 |
2018-10-09 |
Abbvie Inc. |
LRP-8 binding dual variable domain immunoglobulin proteins
|
|
WO2016115345A1
(en)
|
2015-01-14 |
2016-07-21 |
The Brigham And Women's Hospital, |
Treatment of cancer with anti-lap monoclonal antibodies
|
|
CN107810198B
(zh)
|
2015-05-29 |
2021-09-03 |
艾伯维公司 |
抗cd40抗体及其用途
|
|
TW201710286A
(zh)
|
2015-06-15 |
2017-03-16 |
艾伯維有限公司 |
抗vegf、pdgf及/或其受體之結合蛋白
|
|
CA2990360C
(en)
|
2015-06-24 |
2024-02-13 |
Janssen Pharmaceutica Nv |
Anti-vista antibodies and fragments
|
|
AU2016285552B2
(en)
|
2015-06-29 |
2022-10-13 |
Immunogen, Inc. |
Anti-CD123 antibodies and conjugates and derivatives thereof
|
|
MY192146A
(en)
|
2015-11-10 |
2022-08-01 |
Medimmune Llc |
Binding molecules specific for asct2 and uses thereof
|
|
WO2017137830A1
(en)
|
2016-02-12 |
2017-08-17 |
Janssen Pharmaceutica Nv |
Anti-vista (b7h5) antibodies
|
|
CN116284392A
(zh)
|
2016-03-10 |
2023-06-23 |
艾科赛扬制药股份有限公司 |
活化素2型受体结合蛋白及其用途
|
|
WO2017161206A1
(en)
|
2016-03-16 |
2017-09-21 |
Halozyme, Inc. |
Conjugates containing conditionally active antibodies or antigen-binding fragments thereof, and methods of use
|
|
CN109071653A
(zh)
|
2016-03-29 |
2018-12-21 |
詹森生物科技公司 |
用增加的抗-il12和/或-23抗体给药间隔治疗牛皮癣
|
|
WO2017175058A1
(en)
|
2016-04-07 |
2017-10-12 |
Janssen Pharmaceutica Nv |
Anti-vista antibodies and fragments, uses thereof, and methods of identifying same
|
|
WO2017185037A1
(en)
|
2016-04-22 |
2017-10-26 |
Acceleron Pharma Inc. |
Alk7 binding proteins and uses thereof
|
|
JP6871948B2
(ja)
|
2016-04-27 |
2021-05-19 |
アッヴィ・インコーポレイテッド |
抗il−13抗体を使用する、il−13活性が有害である疾患の治療方法
|
|
US20180126000A1
(en)
|
2016-06-02 |
2018-05-10 |
Abbvie Inc. |
Glucocorticoid receptor agonist and immunoconjugates thereof
|
|
AU2017279550A1
(en)
|
2016-06-08 |
2019-01-03 |
Abbvie Inc. |
Anti-B7-H3 antibodies and antibody drug conjugates
|
|
WO2017214322A1
(en)
|
2016-06-08 |
2017-12-14 |
Abbvie Inc. |
Anti-b7-h3 antibodies and antibody drug conjugates
|
|
MX2018015285A
(es)
|
2016-06-08 |
2019-09-18 |
Abbvie Inc |
Anticuerpos anti-b7-h3 y conjugados de anticuerpo y farmaco.
|
|
GB201610198D0
(en)
|
2016-06-10 |
2016-07-27 |
Ucb Biopharma Sprl |
Anti-ige antibodies
|
|
CA3037961A1
(en)
|
2016-09-30 |
2018-04-05 |
Janssen Biotech, Inc. |
Safe and effective method of treating psoriasis with anti-il23 specific antibody
|
|
US11208474B2
(en)
|
2016-11-16 |
2021-12-28 |
Janssen Biotech, Inc. |
Method of treating psoriasis with anti-IL23 specific antibody
|
|
EP3544628A4
(en)
|
2016-11-23 |
2020-11-18 |
Immunoah Therapeutics, Inc. |
4-1BB BINDING PROTEINS AND THEIR USES
|
|
TN2019000164A1
(en)
|
2016-11-23 |
2020-10-05 |
Bioverativ Therapeutics Inc |
Mono- and bispecific antibodies binding to coagulation factor ix and coagulation factor x
|
|
US20180230218A1
(en)
|
2017-01-04 |
2018-08-16 |
Immunogen, Inc. |
Met antibodies and immunoconjugates and uses thereof
|
|
EP3565845A4
(en)
|
2017-01-06 |
2020-10-07 |
Biosion, Inc. |
ERBB2 ANTIBODIES AND THEIR USES
|
|
WO2018140121A1
(en)
|
2017-01-30 |
2018-08-02 |
Janssen Biotech, Inc. |
Anti-tnf antibodies, compositions, and methods for the treatment of active psoriatic arthritis
|
|
MX2019009377A
(es)
|
2017-02-07 |
2019-12-11 |
Janssen Biotech Inc |
Anticuerpos anti-tnf, composiciones y metodos para el tratamiento de la espondilitis anquilosante activa.
|
|
EP3625254B1
(en)
|
2017-07-31 |
2023-12-13 |
F. Hoffmann-La Roche AG |
Three-dimensional structure-based humanization method
|
|
US20200284810A1
(en)
|
2017-09-05 |
2020-09-10 |
Immunogen, Inc. |
Methods for detection of folate receptor 1 in a patient sample
|
|
TW201922780A
(zh)
|
2017-09-25 |
2019-06-16 |
美商健生生物科技公司 |
以抗il12/il23抗體治療狼瘡之安全且有效之方法
|
|
EP3694552A1
(en)
|
2017-10-10 |
2020-08-19 |
Tilos Therapeutics, Inc. |
Anti-lap antibodies and uses thereof
|
|
JP2021502349A
(ja)
|
2017-11-06 |
2021-01-28 |
ヤンセン バイオテツク,インコーポレーテツド |
抗il23特異的抗体で乾癬性関節炎を治療する安全かつ有効な方法
|
|
WO2019150309A1
(en)
|
2018-02-02 |
2019-08-08 |
Hammack Scott |
Modulators of gpr68 and uses thereof for treating and preventing diseases
|
|
KR20250139415A
(ko)
|
2018-02-14 |
2025-09-23 |
호라이즌 테라퓨틱스 아일랜드 디에이씨 |
고양이 맥도너 육종(fms)-유사 티로신 키나제 3 수용체 리간드(flt3l)에 대한 항체 및 자가면역 및 염증 질환을 치료하기 위한 이의 용도
|
|
MX2020009265A
(es)
|
2018-03-05 |
2020-10-01 |
Janssen Biotech Inc |
Metodos para tratar la enfermedad de crohn con un anticuerpo especifico anti-il23.
|
|
JP7269963B2
(ja)
|
2018-06-08 |
2023-05-09 |
クリスタル バイオサイエンス インコーポレイテッド |
同じ軽鎖iを有する多様な抗体を産生するためのトランスジェニック動物
|
|
WO2019240998A1
(en)
|
2018-06-13 |
2019-12-19 |
Crystal Bioscience Inc. |
Production of antibodies by modification of an autonomous heavy chain variable domain by gene conversion
|
|
WO2019241002A1
(en)
|
2018-06-13 |
2019-12-19 |
Crystal Bioscience Inc. |
Transgenic chicken that makes antibodies with long cdr-h3s stabilized by multiple disulfide bridges and diversified by gene conversion
|
|
WO2020014306A1
(en)
|
2018-07-10 |
2020-01-16 |
Immunogen, Inc. |
Met antibodies and immunoconjugates and uses thereof
|
|
US20200025776A1
(en)
|
2018-07-18 |
2020-01-23 |
Janssen Biotech, Inc. |
Sustained Response Predictors After Treatment With Anti-IL23 Specific Antibody
|
|
IL326284A
(en)
|
2018-09-24 |
2026-04-01 |
Janssen Biotech Inc |
A safe and effective method for treating ulcerative colitis with an anti-IL12/IL23 antibody
|
|
CN113164780A
(zh)
|
2018-10-10 |
2021-07-23 |
泰洛斯治疗公司 |
抗lap抗体变体及其用途
|
|
WO2020106358A1
(en)
|
2018-11-20 |
2020-05-28 |
Takeda Vaccines, Inc. |
Novel anti-zika virus antibodies and uses thereof
|
|
IL283192B2
(en)
|
2018-11-20 |
2025-10-01 |
Janssen Biotech Inc |
A safe and effective method for treating psoriasis with a specific anti-IL-23 antibody
|
|
MA54562A
(fr)
|
2018-12-18 |
2021-10-27 |
Janssen Biotech Inc |
Méthode sûre et efficace de traitement du lupus avec un anticorps anti-il12/il23
|
|
US12467062B2
(en)
|
2018-12-21 |
2025-11-11 |
Compass Therapeutics Llc |
Transgenic mouse expressing common human light chain
|
|
JP7689074B2
(ja)
|
2019-01-15 |
2025-06-05 |
ヤンセン バイオテツク,インコーポレーテツド |
若年性特発性関節炎の治療のための抗tnf抗体、組成物、及び方法
|
|
WO2020152544A1
(en)
|
2019-01-23 |
2020-07-30 |
Janssen Biotech, Inc. |
Anti-tnf antibody compositions for use in methods for the treatment of psoriatic arthritis
|
|
WO2020183269A1
(en)
|
2019-03-14 |
2020-09-17 |
Janssen Biotech, Inc. |
Manufacturing methods for producing anti-tnf antibody compositions
|
|
KR20210141998A
(ko)
|
2019-03-14 |
2021-11-23 |
얀센 바이오테크 인코포레이티드 |
항-tnf 항체 조성물의 제조 방법
|
|
EP3938384A4
(en)
|
2019-03-14 |
2022-12-28 |
Janssen Biotech, Inc. |
PREPARATION PROCEDURES FOR THE PREPARATION OF ANTI-IL12/IL23 ANTIBODY COMPOSITIONS
|
|
EA202192505A1
(ru)
|
2019-03-14 |
2022-03-29 |
Янссен Байотек, Инк. |
Способы получения композиций антитела к фно
|
|
JP2022526493A
(ja)
|
2019-03-18 |
2022-05-25 |
ヤンセン バイオテツク,インコーポレーテツド |
抗il12/il23抗体を用いた小児被験者の乾癬の治療方法
|
|
JP7805788B2
(ja)
|
2019-05-23 |
2026-01-26 |
ヤンセン バイオテツク,インコーポレーテツド |
Il-23及びtnfアルファに対する抗体の併用療法による炎症性腸疾患の治療方法
|
|
MX2021014882A
(es)
|
2019-06-03 |
2022-03-25 |
Janssen Biotech Inc |
Anticuerpos anti-tnf, composiciones y métodos para el tratamiento de la espondilitis anquilosante activa.
|
|
JP2022536279A
(ja)
|
2019-06-03 |
2022-08-15 |
ヤンセン バイオテツク,インコーポレーテツド |
乾癬性関節炎を治療するための抗tnf抗体組成物及び方法
|
|
MA56124A
(fr)
|
2019-06-04 |
2022-04-13 |
Janssen Biotech Inc |
Méthode sûre et efficace de traitement de l'arthrite psoriasique au moyen d'un anticorps spécifique anti-il23
|
|
WO2021028752A1
(en)
|
2019-08-15 |
2021-02-18 |
Janssen Biotech, Inc. |
Anti-tfn antibodies for treating type i diabetes
|
|
KR20220137698A
(ko)
|
2020-02-05 |
2022-10-12 |
라리마 테라퓨틱스, 인코포레이티드 |
Tat 펩티드 결합 단백질 및 이의 용도
|
|
US20230272056A1
(en)
|
2020-04-09 |
2023-08-31 |
Merck Sharp & Dohme Llc |
Affinity matured anti-lap antibodies and uses thereof
|
|
US20210347880A1
(en)
|
2020-05-05 |
2021-11-11 |
Janssen Biotech, Inc. |
Methods of Treating Crohn's Disease with Anti-IL23 Specific Antibody
|
|
IL298389A
(en)
|
2020-05-21 |
2023-01-01 |
Janssen Biotech Inc |
Method of treating inflammatory bowel disease with a combination therapy of antibodies to il-23 and tnf alpha
|
|
WO2022013745A1
(en)
|
2020-07-13 |
2022-01-20 |
Janssen Biotech, Inc. |
Safe and effective method of treating psoriatic arthritis with anti-il23 specific antibody
|
|
US20220073603A1
(en)
|
2020-07-30 |
2022-03-10 |
Janssen Biotech, Inc. |
Method of Treating Psoriasis in Pediatric Subjects with Anti-IL12/IL23 Antibody
|
|
BR112023004415A2
(pt)
|
2020-09-11 |
2023-05-09 |
Medimmune Ltd |
Moléculas terapêuticas de ligação a b7-h4
|
|
CN116615455A
(zh)
|
2020-09-12 |
2023-08-18 |
免疫医疗有限公司 |
用于抗b7h4抗体-药物缀合物疗法的评分方法
|
|
AR124681A1
(es)
|
2021-01-20 |
2023-04-26 |
Abbvie Inc |
Conjugados anticuerpo-fármaco anti-egfr
|
|
EP4305062A1
(en)
|
2021-03-12 |
2024-01-17 |
Janssen Biotech, Inc. |
Method of treating psoriatic arthritis patients with inadequate response to tnf therapy with anti-il23 specific antibody
|
|
IL305802A
(en)
|
2021-03-12 |
2023-11-01 |
Janssen Biotech Inc |
A safe and effective method for the treatment of rheumatoid arthritis with a specific anti-IL23 antibody
|
|
BR112023017490A2
(pt)
|
2021-03-17 |
2023-11-07 |
Receptos Llc |
Métodos de tratamento de dermatite atópica com anticorpos anti il-13
|
|
IL305690B2
(en)
|
2021-03-18 |
2025-10-01 |
Medimmune Ltd |
A therapeutic binding molecule that binds to CCR9
|
|
US20240262893A1
(en)
|
2021-05-12 |
2024-08-08 |
Applied Biomedical Science Institute |
Binding polypeptides against sars cov-2 and uses thereof
|
|
JP2024527581A
(ja)
|
2021-07-09 |
2024-07-25 |
ヤンセン バイオテツク,インコーポレーテツド |
抗il12/il23抗体組成物を生産するための製造方法
|
|
EP4367136A1
(en)
|
2021-07-09 |
2024-05-15 |
Janssen Biotech, Inc. |
Manufacturing methods for producing anti-tnf antibody compositions
|
|
US12534524B2
(en)
|
2021-07-09 |
2026-01-27 |
Janssen Biotech, Inc. |
Manufacturing methods for producing anti-TNF antibody compositions
|
|
US11807685B2
(en)
|
2021-08-05 |
2023-11-07 |
The Uab Research Foundation |
Anti-CD47 antibody and uses thereof
|
|
EP4423126B1
(en)
|
2021-10-29 |
2026-05-06 |
Janssen Biotech, Inc. |
Methods of treating crohn's disease with anti-il23 specific antibody
|
|
EP4433501A1
(en)
|
2021-11-15 |
2024-09-25 |
Janssen Biotech, Inc. |
Methods of treating crohn's disease with anti-il23 specific antibody
|
|
US20230159633A1
(en)
|
2021-11-23 |
2023-05-25 |
Janssen Biotech, Inc. |
Method of Treating Ulcerative Colitis with Anti-IL23 Specific Antibody
|
|
TW202348252A
(zh)
|
2022-02-16 |
2023-12-16 |
英商梅迪繆思有限公司 |
用治療性結合分子治療癌症的組合療法
|
|
JP2025512860A
(ja)
|
2022-03-30 |
2025-04-22 |
ヤンセン バイオテツク,インコーポレーテツド |
Il-23に特異的な抗体によって軽度から中等度の乾癬を治療する方法
|
|
EP4526342A1
(en)
|
2022-05-18 |
2025-03-26 |
Janssen Biotech, Inc. |
Method for evaluating and treating psoriatic arthritis with il23 antibody
|
|
AU2023383916A1
(en)
|
2022-11-22 |
2025-07-10 |
Janssen Biotech, Inc. |
Method of treating ulcerative colitis with anti-il23 specific antibody
|
|
WO2024169990A1
(zh)
|
2023-02-13 |
2024-08-22 |
浙江大学绍兴研究院 |
双特异性抗体及其应用
|
|
AU2024318876A1
(en)
|
2023-07-31 |
2026-03-19 |
Astrazeneca Ab |
Cd123 antibody-drug conjugates and methods of using the same
|
|
WO2025184208A1
(en)
|
2024-02-27 |
2025-09-04 |
Bristol-Myers Squibb Company |
Anti-ceacam5 antibodies and uses thereof
|
|
CA3249015A1
(en)
|
2024-03-20 |
2025-10-31 |
Janssen Biotech, Inc. |
Methods of treating crohn’s disease with anti-il23 specific antibody
|
|
WO2025262604A1
(en)
|
2024-06-17 |
2025-12-26 |
Janssen Biotech, Inc. |
Methods of treating crohn's disease with anti-il23 specific antibody
|
|
CA3258952A1
(en)
|
2024-06-27 |
2026-03-01 |
Janssen Biotech, Inc. |
Methods of treating ulcerative colitis with anti-il23 specific antibody
|