PT95100A - Processo para a preparacao de n-hidroxi-di-benz/b,e/oxepin-alquilaminas e de analogos heterociclicos relacionados com amidas de acidos alcanoicos e de composicoes farmaceuticas que os contem - Google Patents

Processo para a preparacao de n-hidroxi-di-benz/b,e/oxepin-alquilaminas e de analogos heterociclicos relacionados com amidas de acidos alcanoicos e de composicoes farmaceuticas que os contem

Info

Publication number: PT95100A
Authority: PT; Portugal
Prior art keywords: hydroxy; alkylamins; oxepin; benz; amide
Prior art date: 1989-08-25

Application number

PT95100A

Other languages

English (en)

Other versions

PT95100B (pt

Inventor

Grover Cleveland Helsley

Richard C Allen

Russel Richard Lee Hamer

Brian S Freed

John I White

Lawrence Leo Martin

Original Assignee

Hoechst Roussel Pharma

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1989-08-25

Filing date

1990-08-24

Publication date

1991-04-18

1990-08-24 Application filed by Hoechst Roussel Pharma filed Critical Hoechst Roussel Pharma

1991-04-18 Publication of PT95100A publication Critical patent/PT95100A/pt

1997-05-28 Publication of PT95100B publication Critical patent/PT95100B/pt

Links

150000001408 amides Chemical class 0.000 title abstract 2
239000002253 acid Substances 0.000 title 1
150000007513 acids Chemical class 0.000 title 1
239000008194 pharmaceutical composition Substances 0.000 title 1
UHOVQNZJYSORNB-UHFFFAOYSA-N Benzene Chemical compound C1=CC=CC=C1 UHOVQNZJYSORNB-UHFFFAOYSA-N 0.000 abstract 3
229910052739 hydrogen Inorganic materials 0.000 abstract 3
239000001257 hydrogen Substances 0.000 abstract 3
125000004435 hydrogen atom Chemical class [H]* 0.000 abstract 3
125000002252 acyl group Chemical group 0.000 abstract 2
YTPLMLYBLZKORZ-UHFFFAOYSA-N Thiophene Chemical group C=1C=CSC=1 YTPLMLYBLZKORZ-UHFFFAOYSA-N 0.000 abstract 1
230000000202 analgesic effect Effects 0.000 abstract 1
125000004432 carbon atom Chemical group C* 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
125000000753 cycloalkyl group Chemical group 0.000 abstract 1
229910052736 halogen Inorganic materials 0.000 abstract 1
150000002367 halogens Chemical class 0.000 abstract 1
125000000623 heterocyclic group Chemical group 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1
125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D313/00—Heterocyclic compounds containing rings of more than six members having one oxygen atom as the only ring hetero atom
- C07D313/02—Seven-membered rings
- C07D313/06—Seven-membered rings condensed with carbocyclic rings or ring systems
- C07D313/10—Seven-membered rings condensed with carbocyclic rings or ring systems condensed with two six-membered rings
- C07D313/12—[b,e]-condensed

Landscapes

Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
Medicinal Chemistry (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Engineering & Computer Science (AREA)
Pain & Pain Management (AREA)
Bioinformatics & Cheminformatics (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Biomedical Technology (AREA)
Rheumatology (AREA)
Dermatology (AREA)
Epidemiology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Pyrane Compounds (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Epoxy Compounds (AREA)

PT95100A 1989-08-25 1990-08-24 Processo para a preparacao de n-hidroxi-di-benz/b,e/oxepin-alquilaminas e de analogos heterociclicos relacionados com amidas de acidos alcanoicos e de composicoes farmaceuticas que os contem PT95100B (pt)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US39860789A	1989-08-25	1989-08-25

Publications (2)

Publication Number	Publication Date
PT95100A true PT95100A (pt)	1991-04-18
PT95100B PT95100B (pt)	1997-05-28

Family

ID=23576030

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
PT95100A PT95100B (pt)	1989-08-25	1990-08-24	Processo para a preparacao de n-hidroxi-di-benz/b,e/oxepin-alquilaminas e de analogos heterociclicos relacionados com amidas de acidos alcanoicos e de composicoes farmaceuticas que os contem

Country Status (17)

Country	Link
EP (1)	EP0419844B1 (pt)
JP (1)	JPH0778060B2 (pt)
KR (1)	KR0156537B1 (pt)
AT (1)	ATE120741T1 (pt)
AU (2)	AU636644B2 (pt)
CA (1)	CA2023951C (pt)
DE (1)	DE69018352T2 (pt)
DK (1)	DK0419844T3 (pt)
ES (1)	ES2070962T3 (pt)
FI (1)	FI90539C (pt)
IE (1)	IE66683B1 (pt)
IL (1)	IL95477A (pt)
NO (1)	NO174295C (pt)
NZ (1)	NZ235025A (pt)
PT (1)	PT95100B (pt)
TW (1)	TW209861B (pt)
ZA (1)	ZA906747B (pt)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO1990003373A1 (fr) *	1988-09-20	1990-04-05	Hisamitsu Pharmaceutical Co., Inc.	NOUVEAUX DERIVES DE DIBENZ[b,e]OXEPINE
KR100280865B1 (ko) *	1998-04-03	2001-02-01	이태근	닭및지렁이의순환적활용에의한음식물쓰레기의소멸처리방법
KR19990046663A (ko) *	1999-04-12	1999-07-05	차만수	어즙흡착발효사료제조방법

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4585788A (en) *	1973-09-06	1986-04-29	American Hoechst Corporation	6,11-dihydrodibenz[b,e]oxepin-acetic acids and derivatives
US4496580A (en) *	1981-07-23	1985-01-29	Hoechst-Roussel Pharmaceuticals Inc.	Oxothienobenzoxepins
JPS5821679A (ja) *	1981-07-31	1983-02-08	メルク　エンド　カムパニー　インコーポレーテツド	ジベンツ〔ｂ，ｅ〕オキセピン化合物
US4477465A (en) *	1983-03-10	1984-10-16	Hoechst-Roussel Pharmaceuticals Inc.	Substituted 4,10-dihydro-10-oxothieno benzoxepins
JPS6310784A (ja) *	1986-03-03	1988-01-18	Kyowa Hakko Kogyo Co Ltd	抗アレルギー剤
US4981865A (en)	1989-05-26	1991-01-01	Warner-Lambert Co.	N-hydroxyamide, N-hydroxythioamide, hydroxyurea, and N-hydroxythiourea derivatives of selected nsaids as antiinflammatory agents

1990
- 1990-04-27 TW TW079103421A patent/TW209861B/zh active
- 1990-08-22 EP EP90116052A patent/EP0419844B1/en not_active Expired - Lifetime
- 1990-08-22 DE DE69018352T patent/DE69018352T2/de not_active Expired - Fee Related
- 1990-08-22 ES ES90116052T patent/ES2070962T3/es not_active Expired - Lifetime
- 1990-08-22 DK DK90116052.3T patent/DK0419844T3/da active
- 1990-08-22 AT AT90116052T patent/ATE120741T1/de not_active IP Right Cessation
- 1990-08-23 IL IL95477A patent/IL95477A/en not_active IP Right Cessation
- 1990-08-23 NZ NZ235025A patent/NZ235025A/xx unknown
- 1990-08-23 FI FI904184A patent/FI90539C/fi not_active IP Right Cessation
- 1990-08-24 KR KR1019900013079A patent/KR0156537B1/ko not_active Expired - Fee Related
- 1990-08-24 ZA ZA906747A patent/ZA906747B/xx unknown
- 1990-08-24 IE IE309390A patent/IE66683B1/en not_active IP Right Cessation
- 1990-08-24 JP JP2221430A patent/JPH0778060B2/ja not_active Expired - Lifetime
- 1990-08-24 CA CA002023951A patent/CA2023951C/en not_active Expired - Fee Related
- 1990-08-24 PT PT95100A patent/PT95100B/pt not_active IP Right Cessation
- 1990-08-24 AU AU61318/90A patent/AU636644B2/en not_active Ceased
- 1990-08-24 NO NO903727A patent/NO174295C/no unknown
1993
- 1993-02-19 AU AU33758/93A patent/AU658264B2/en not_active Ceased

Also Published As

Publication number	Publication date
AU3375893A (en)	1993-07-15
EP0419844B1 (en)	1995-04-05
AU658264B2 (en)	1995-04-06
CA2023951C (en)	2001-04-03
IL95477A0 (en)	1991-06-30
PT95100B (pt)	1997-05-28
DE69018352D1 (de)	1995-05-11
FI90539B (fi)	1993-11-15
IE903093A1 (en)	1991-02-27
DK0419844T3 (da)	1995-08-28
ES2070962T3 (es)	1995-06-16
KR0156537B1 (ko)	1999-10-01
DE69018352T2 (de)	1995-10-26
TW209861B (pt)	1993-07-21
NZ235025A (en)	1993-02-25
AU636644B2 (en)	1993-05-06
NO174295B (no)	1994-01-03
FI90539C (fi)	1994-02-25
CA2023951A1 (en)	1991-02-26
NO174295C (no)	1994-04-13
EP0419844A1 (en)	1991-04-03
KR910004593A (ko)	1991-03-29
IL95477A (en)	1998-03-10
JPH0390077A (ja)	1991-04-16
FI904184A0 (fi)	1990-08-23
IE66683B1 (en)	1996-01-24
ZA906747B (en)	1991-06-26
JPH0778060B2 (ja)	1995-08-23
AU6131890A (en)	1991-02-28
NO903727L (no)	1991-02-26
NO903727D0 (no)	1990-08-24
ATE120741T1 (de)	1995-04-15

Legal Events

Date	Code	Title	Description
1991-04-18	BB1A	Laying open of patent application	Effective date: 19901210
1997-05-30	FG3A	Patent granted, date of granting	Effective date: 19970218
2005-10-31	MM3A	Annulment or lapse	Effective date: 20050818

Publication	Publication Date	Title
PT91931A (pt)	1990-04-30	Processo de preparacao de derivados de acido fenilalcanoico e de composicoes farmaceuticas que os contem
NZ238181A (en)	1993-02-25	N-(1-substituted-piperidinyl(alkyl))carbamic acid, urea and carboxamide derivatives and homologues thereof; preparatory processes and pharmaceutical compositions
PT94925A (pt)	1991-04-18	Processo para a preparacao de derivados de tiazol e de composicoes farmaceuticas que os contem
PT98114A (pt)	1992-03-31	Processo para a prparacao de 1-indolilalquil-4-(alcoxipirimidinil)piperazinas e de composicoes farmaceuticas que as contem
PT96145A (pt)	1991-09-30	Processo para a preparacao de novos derivados de aminoacidos e de composicoes farmaceuticas que os contem
BR9401503A (pt)	1994-10-25	Derivados de cefalosporina, compostos, processo para a fabricação dos ditos compostos, preparação farmacêutica e uso dos ditos compostos
ATE145906T1 (de)	1996-12-15	Benzamid-derivate
PT96030A (pt)	1991-09-13	Processo para a preparacao de aminocarbonilcarbamatos relacionados com fisoestigmina e de composicoes farmaceuticas que os contem
PT94297A (pt)	1991-02-08	Processo para a preparacao de n-hetero-aril-purin-6-aminas e de composicoes farmaceuticas que as contem
HU9200321D0 (en)	1992-04-28	Process for the production of n-(aryl-oxi-alkyl)-heteroaryl-8-azabicyclo(3.2.1)-octanes and medical preparations containing them
IT1211792B (it)	1989-11-03	O-alcanoil derivati dell'acido 3ammino-2-idrossipropansolfonico adattivita'anticonvulsivante e loro composizioni farmaceutiche per il trattamento terapeutico dell'epilessia
NO164593C (no)	1990-10-24	Analogifremgangsmaate for fremstilling av terapeutisk aktive karbamat- eller urea-derivater.
PT84680B (pt)	1989-12-29	Processo para a preparacao de derivados de 1,5-benzotiazepina e de composicoes farmaceuticas que os contem
NO903727L (no)	1991-02-26	N-hydroksydibenz(b,e)oksepinalkylaminer og -alkansyreamider og beslektede heterocykliske analoger samt fremgangsmaate for deres fremstilling.
PT92147A (pt)	1990-05-31	Processo para a preparacao de derivados de pirrolidina
DE69014261D1 (de)	1995-01-05	N-Azabicyclo[3.3.0]octanamide von aromatischen Säuren.