PT96849A - Processo de preparacao de novos derivados da beta-fenil-iso-serina e de beta-fenil-iso-serina-(2r,2s) - Google Patents

Processo de preparacao de novos derivados da beta-fenil-iso-serina e de beta-fenil-iso-serina-(2r,2s)

Info

Publication number: PT96849A
Authority: PT; Portugal
Prior art keywords: iso; phenyl; beta; derivatives; serin
Prior art date: 1990-02-21

Application number

PT96849A

Other languages

English (en)

Other versions

PT96849B (pt

Inventor

Jean-Pierre Duchesne

Michel Mulhauser

Original Assignee

Rhone Poulenc Rorer Sa

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1990-02-21

Filing date

1991-02-21

Publication date

1991-10-31

1991-02-21 Application filed by Rhone Poulenc Rorer Sa filed Critical Rhone Poulenc Rorer Sa

1991-10-31 Publication of PT96849A publication Critical patent/PT96849A/pt

1998-07-31 Publication of PT96849B publication Critical patent/PT96849B/pt

Links

RZARFIRJROUVLM-GVHYBUMESA-N (3r)-3-amino-2-hydroxy-3-phenylpropanoic acid Chemical compound OC(=O)C(O)[C@H](N)C1=CC=CC=C1 RZARFIRJROUVLM-GVHYBUMESA-N 0.000 title abstract 2
238000002360 preparation method Methods 0.000 title abstract 2
229930012538 Paclitaxel Natural products 0.000 abstract 1
230000015572 biosynthetic process Effects 0.000 abstract 1
229960001592 paclitaxel Drugs 0.000 abstract 1
238000003786 synthesis reaction Methods 0.000 abstract 1
RCINICONZNJXQF-MZXODVADSA-N taxol Chemical compound O([C@@H]1[C@@]2(C[C@@H](C(C)=C(C2(C)C)[C@H](C([C@]2(C)[C@@H](O)C[C@H]3OC[C@]3([C@H]21)OC(C)=O)=O)OC(=O)C)OC(=O)[C@H](O)[C@@H](NC(=O)C=1C=CC=CC=1)C=1C=CC=CC=1)O)C(=O)C1=CC=CC=C1 RCINICONZNJXQF-MZXODVADSA-N 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C229/34—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton containing six-membered aromatic rings
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D305/00—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms
- C07D305/14—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms condensed with carbocyclic rings or ring systems

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Epoxy Compounds (AREA)
Liquid Developers In Electrophotography (AREA)
Indole Compounds (AREA)

PT96849A 1990-02-21 1991-02-21 Processo de preparacao de novos derivados da beta-fenil-iso-serina e de beta-fenil-iso-serina-(2r,2s) PT96849B (pt)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
FR9002099A FR2658510B1 (fr)	1990-02-21	1990-02-21	Nouveau derive de la beta-phenylisoserine, sa preparation et son emploi.

Publications (2)

Publication Number	Publication Date
PT96849A true PT96849A (pt)	1991-10-31
PT96849B PT96849B (pt)	1998-07-31

Family

ID=9393962

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
PT96849A PT96849B (pt)	1990-02-21	1991-02-21	Processo de preparacao de novos derivados da beta-fenil-iso-serina e de beta-fenil-iso-serina-(2r,2s)

Country Status (23)

Country	Link
US (1)	US5359124A (pt)
EP (1)	EP0515540B1 (pt)
JP (1)	JP3057097B2 (pt)
KR (1)	KR100197481B1 (pt)
AT (1)	ATE108176T1 (pt)
AU (1)	AU642717B2 (pt)
CA (1)	CA2071983C (pt)
CZ (1)	CZ279656B6 (pt)
DE (1)	DE69102762T2 (pt)
DK (1)	DK0515540T3 (pt)
ES (1)	ES2056639T3 (pt)
FI (1)	FI111247B (pt)
FR (1)	FR2658510B1 (pt)
HU (1)	HU209615B (pt)
IE (1)	IE64397B1 (pt)
IL (1)	IL97277A (pt)
NO (1)	NO179865C (pt)
PT (1)	PT96849B (pt)
RU (1)	RU2074172C1 (pt)
SK (1)	SK278304B6 (pt)
WO (1)	WO1991013053A1 (pt)
YU (1)	YU48671B (pt)
ZA (1)	ZA911211B (pt)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5939561A (en) *	1992-03-10	1999-08-17	Rhone-Poulence Rorer S.A.	Process for the preparation of β-phenylisoserine and β-lactam and their analogues
FR2688499B1 (fr)	1992-03-10	1994-05-06	Rhone Poulenc Rorer Sa	Procede de preparation de la beta-phenylisoserine et de ses analogues.
WO1993021173A1 (en) *	1992-04-17	1993-10-28	Abbott Laboratories	Taxol derivatives
IL107950A (en)	1992-12-15	2001-04-30	Upjohn Co	7β, 8β - METHANO-TAXOLS, THEIR PREPARATION AND ANTINEOPLASTIC PHARMACEUTICAL COMPOSITIONS CONTAINING THEM
DE69424166T2 (de) *	1993-06-11	2000-10-05	Pharmacia & Upjohn Co., Kalamazoo	Delta 6, 7-taxolen, antineoplastische verwendung und diese enthaltende pharmazeutische zusammenstellungen
IL127598A (en) *	1994-01-28	2003-04-10	Upjohn Co	Process for preparing isotaxol analogs
US5580899A (en) *	1995-01-09	1996-12-03	The Liposome Company, Inc.	Hydrophobic taxane derivatives
US6107332A (en)	1995-09-12	2000-08-22	The Liposome Company, Inc.	Hydrolysis-promoting hydrophobic taxane derivatives
US6051600A (en) *	1995-09-12	2000-04-18	Mayhew; Eric	Liposomal hydrolysis-promoting hydrophobic taxane derivatives
JP6427097B2 (ja)	2012-06-15	2018-11-21	ザブリガムアンドウィメンズホスピタルインコーポレイテッドＴｈｅＢｒｉｇｈａｍａｎｄＷｏｍｅｎ’ｓＨｏｓｐｉｔａｌ，Ｉｎｃ．	癌を処置するための組成物および該組成物を製造するための方法
WO2015153345A1 (en)	2014-04-03	2015-10-08	Invictus Oncology Pvt. Ltd.	Supramolecular combinatorial therapeutics

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CA1108180A (en) *	1976-07-21	1981-09-01	Hamao Umezawa	Analogs of bestatin
FR2629818B1 (fr) *	1988-04-06	1990-11-16	Centre Nat Rech Scient	Procede de preparation du taxol
FR2629819B1 (fr) *	1988-04-06	1990-11-16	Rhone Poulenc Sante	Procede de preparation de derives de la baccatine iii et de la desacetyl-10 baccatine iii
US5175315A (en) *	1989-05-31	1992-12-29	Florida State University	Method for preparation of taxol using β-lactam
FR2662440B1 (fr) *	1990-05-22	1992-07-31	Rhone Poulenc Sante	Procede de preparation stereoselective de derives de la phenylisoserine.
FR2662441B1 (fr) *	1990-05-22	1992-10-23	Rhone Poulenc Sante	Procede de preparation enantioselective de derives de la phenylisoserine.

1990
- 1990-02-21 FR FR9002099A patent/FR2658510B1/fr not_active Expired - Lifetime
1991
- 1991-02-19 IL IL9727791A patent/IL97277A/en not_active IP Right Cessation
- 1991-02-19 ZA ZA911211A patent/ZA911211B/xx unknown
- 1991-02-20 IE IE58691A patent/IE64397B1/en not_active IP Right Cessation
- 1991-02-20 AT AT91905054T patent/ATE108176T1/de not_active IP Right Cessation
- 1991-02-20 RU SU915053004A patent/RU2074172C1/ru active
- 1991-02-20 CZ CS91438A patent/CZ279656B6/cs not_active IP Right Cessation
- 1991-02-20 EP EP91905054A patent/EP0515540B1/fr not_active Expired - Lifetime
- 1991-02-20 JP JP3505196A patent/JP3057097B2/ja not_active Expired - Lifetime
- 1991-02-20 DK DK91905054.2T patent/DK0515540T3/da active
- 1991-02-20 ES ES91905054T patent/ES2056639T3/es not_active Expired - Lifetime
- 1991-02-20 CA CA002071983A patent/CA2071983C/fr not_active Expired - Lifetime
- 1991-02-20 KR KR1019920701998A patent/KR100197481B1/ko not_active Expired - Lifetime
- 1991-02-20 WO PCT/FR1991/000132 patent/WO1991013053A1/fr not_active Ceased
- 1991-02-20 SK SK438-91A patent/SK278304B6/sk not_active IP Right Cessation
- 1991-02-20 AU AU73453/91A patent/AU642717B2/en not_active Expired
- 1991-02-20 DE DE69102762T patent/DE69102762T2/de not_active Expired - Lifetime
- 1991-02-20 HU HU9202667A patent/HU209615B/hu unknown
- 1991-02-20 US US07/920,508 patent/US5359124A/en not_active Expired - Lifetime
- 1991-02-21 YU YU31191A patent/YU48671B/sh unknown
- 1991-02-21 PT PT96849A patent/PT96849B/pt not_active IP Right Cessation
1992
- 1992-08-17 FI FI923679A patent/FI111247B/fi active
- 1992-08-18 NO NO923226A patent/NO179865C/no not_active IP Right Cessation

Also Published As

Publication number	Publication date
YU31191A (sh)	1993-11-16
NO179865B (no)	1996-09-23
RU2074172C1 (ru)	1997-02-27
KR100197481B1 (ko)	1999-06-15
EP0515540B1 (fr)	1994-07-06
CA2071983A1 (fr)	1991-08-22
IE910586A1 (en)	1991-08-28
HUT61971A (en)	1993-03-29
FI923679L (fi)	1992-08-17
CZ279656B6 (cs)	1995-05-17
FR2658510B1 (fr)	1992-04-30
ES2056639T3 (es)	1994-10-01
FI923679A0 (fi)	1992-08-17
NO179865C (no)	1997-01-02
JPH05504954A (ja)	1993-07-29
IE64397B1 (en)	1995-08-09
AU642717B2 (en)	1993-10-28
ZA911211B (en)	1991-11-27
IL97277A0 (en)	1992-05-25
DE69102762T2 (de)	1994-10-27
DK0515540T3 (da)	1994-08-15
JP3057097B2 (ja)	2000-06-26
HU209615B (en)	1994-09-28
CA2071983C (fr)	2003-03-18
KR927003561A (ko)	1992-12-18
FR2658510A1 (fr)	1991-08-23
DE69102762D1 (de)	1994-08-11
NO923226D0 (no)	1992-08-18
US5359124A (en)	1994-10-25
NO923226L (no)	1992-08-18
WO1991013053A1 (fr)	1991-09-05
EP0515540A1 (fr)	1992-12-02
AU7345391A (en)	1991-09-18
YU48671B (sh)	1999-06-15
IL97277A (en)	1995-12-08
HU9202667D0 (en)	1992-12-28
SK278304B6 (en)	1996-09-04
PT96849B (pt)	1998-07-31
CS9100438A2 (en)	1991-09-15
FI111247B (fi)	2003-06-30
ATE108176T1 (de)	1994-07-15

Legal Events

Date	Code	Title	Description
1991-10-31	BB1A	Laying open of patent application	Effective date: 19910704
1998-07-31	FG3A	Patent granted, date of granting	Effective date: 19980413
2002-02-28	PD3A	Change of proprietorship	Owner name: AVENTIS PHARMA, S.A. Effective date: 20011116
2013-04-23	MM4A	Annulment/lapse due to non-payment of fees, searched and examined patent	Free format text: MAXIMUM VALIDITY LIMIT REACHED Effective date: 20130415

Publication	Publication Date	Title
LU88712I2 (fr)	1996-08-23	TAXOTERE-Décotaxel
MX9203053A (es)	1992-12-01	Derivados de aza nor bornano.
TR199902626T2 (xx)	2000-06-21	Enflamasyon tedavisi i�in ikameli benzopiran t�revleri.
TR27835A (tr)	1995-08-31	Sübstitüe edilmis azadiokzasikloalkenler.
DE69325454D1 (de)	1999-07-29	Taxol-derivate
NO962286L (no)	1996-06-03	N-substituerte azabicykloalkanderivater som neuroleptika etc.
DE69433984D1 (de)	2004-10-14	Arylpiperazinderivate von indol als liganden der rezeptoren 5 ht1-like, 5 ht1b und 5 ht1d
NO923226D0 (no)	1992-08-18	Nytt beta-fenylisoserinderivat, dets fremstilling og anvendelse
LV11899A (lv)	1997-12-20	Jauni adenozina atvasinajumi to iegusanas panemiens
FI902901A0 (fi)	1990-06-11	Dibenzol/1,5/dioxocin-5-one-derivat, deras anvaendning i laekemedel och foerfarande foer deras framstaellning.
ATE138662T1 (de)	1996-06-15	Antibiotische 7-aminonaphthazarinderivate
NO307706B1 (no)	2000-05-15	Substituerte aryltiolalkyltiopyridiner
DK0713485T3 (da)	1998-12-07	Thiocarbamoylforbindelser som mikrobicider
SE8601344L (sv)	1986-03-21	Derivat av 11-desoxi-17alfa-hydroxikortikosteron
ATE160806T1 (de)	1997-12-15	N1-trifluoralkyl substituierte 2-nitro-p- phenylendiaminfarbstoffe
DE69104363D1 (de)	1994-11-03	Vinylsulfonyl pristinamycine und deren herstellung.
ATE139773T1 (de)	1996-07-15	Neue 1-aryl-4-piperazinyl- cyclohexancarbonsäurenitrile, ihre herstellung und verwendung