NO923226L - Nytt beta-fenylisoserinderivat, dets fremstilling og anvendelse - Google Patents

Nytt beta-fenylisoserinderivat, dets fremstilling og anvendelse

Info

Publication number: NO923226L
Authority: NO; Norway
Prior art keywords: preparation; derivative; pct; phenylisoserin; new beta
Prior art date: 1990-02-21

Application number

NO92923226A

Other languages

English (en)

Other versions

NO923226D0 (no

NO179865C (no

NO179865B (no

Inventor

Jean-Pierre Duchesne

Michel Mulhauser

Original Assignee

Rhone Poulenc Rorer Sa

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1990-02-21

Filing date

1992-08-18

Publication date

1992-08-18

1992-08-18 Application filed by Rhone Poulenc Rorer Sa filed Critical Rhone Poulenc Rorer Sa

1992-08-18 Publication of NO923226D0 publication Critical patent/NO923226D0/no

1992-08-18 Publication of NO923226L publication Critical patent/NO923226L/no

1996-09-23 Publication of NO179865B publication Critical patent/NO179865B/no

1997-01-02 Publication of NO179865C publication Critical patent/NO179865C/no

Links

238000002360 preparation method Methods 0.000 title abstract 2
RZARFIRJROUVLM-UHFFFAOYSA-N 3-azaniumyl-2-hydroxy-3-phenylpropanoate Chemical class OC(=O)C(O)C(N)C1=CC=CC=C1 RZARFIRJROUVLM-UHFFFAOYSA-N 0.000 title 1
RZARFIRJROUVLM-GVHYBUMESA-N (3r)-3-amino-2-hydroxy-3-phenylpropanoic acid Chemical class OC(=O)C(O)[C@H](N)C1=CC=CC=C1 RZARFIRJROUVLM-GVHYBUMESA-N 0.000 abstract 1
229930012538 Paclitaxel Natural products 0.000 abstract 1
230000015572 biosynthetic process Effects 0.000 abstract 1
229960001592 paclitaxel Drugs 0.000 abstract 1
238000003786 synthesis reaction Methods 0.000 abstract 1
RCINICONZNJXQF-MZXODVADSA-N taxol Chemical compound O([C@@H]1[C@@]2(C[C@@H](C(C)=C(C2(C)C)[C@H](C([C@]2(C)[C@@H](O)C[C@H]3OC[C@]3([C@H]21)OC(C)=O)=O)OC(=O)C)OC(=O)[C@H](O)[C@@H](NC(=O)C=1C=CC=CC=1)C=1C=CC=CC=1)O)C(=O)C1=CC=CC=C1 RCINICONZNJXQF-MZXODVADSA-N 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C229/34—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton containing six-membered aromatic rings
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D305/00—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms
- C07D305/14—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms condensed with carbocyclic rings or ring systems

Landscapes

Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Chemical Kinetics & Catalysis (AREA)
Animal Behavior & Ethology (AREA)
Medicinal Chemistry (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Epoxy Compounds (AREA)
Liquid Developers In Electrophotography (AREA)
Indole Compounds (AREA)

NO923226A 1990-02-21 1992-08-18 Nytt -fenylisoserinderivat og dets fremstilling NO179865C (no)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
FR9002099A FR2658510B1 (fr)	1990-02-21	1990-02-21	Nouveau derive de la beta-phenylisoserine, sa preparation et son emploi.
PCT/FR1991/000132 WO1991013053A1 (fr)	1990-02-21	1991-02-20	DERIVE DE LA β-PHENYLISOSERINE, SA PREPARATION ET SON EMPLOI

Publications (4)

Publication Number	Publication Date
NO923226D0 NO923226D0 (no)	1992-08-18
NO923226L true NO923226L (no)	1992-08-18
NO179865B NO179865B (no)	1996-09-23
NO179865C NO179865C (no)	1997-01-02

Family

ID=9393962

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO923226A NO179865C (no)	1990-02-21	1992-08-18	Nytt -fenylisoserinderivat og dets fremstilling

Country Status (23)

Country	Link
US (1)	US5359124A (no)
EP (1)	EP0515540B1 (no)
JP (1)	JP3057097B2 (no)
KR (1)	KR100197481B1 (no)
AT (1)	ATE108176T1 (no)
AU (1)	AU642717B2 (no)
CA (1)	CA2071983C (no)
CZ (1)	CZ279656B6 (no)
DE (1)	DE69102762T2 (no)
DK (1)	DK0515540T3 (no)
ES (1)	ES2056639T3 (no)
FI (1)	FI111247B (no)
FR (1)	FR2658510B1 (no)
HU (1)	HU209615B (no)
IE (1)	IE64397B1 (no)
IL (1)	IL97277A (no)
NO (1)	NO179865C (no)
PT (1)	PT96849B (no)
RU (1)	RU2074172C1 (no)
SK (1)	SK278304B6 (no)
WO (1)	WO1991013053A1 (no)
YU (1)	YU48671B (no)
ZA (1)	ZA911211B (no)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5939561A (en) *	1992-03-10	1999-08-17	Rhone-Poulence Rorer S.A.	Process for the preparation of β-phenylisoserine and β-lactam and their analogues
FR2688499B1 (fr) *	1992-03-10	1994-05-06	Rhone Poulenc Rorer Sa	Procede de preparation de la beta-phenylisoserine et de ses analogues.
DE69325454T2 (de) *	1992-04-17	2000-01-20	Abbott Laboratories, Abbott Park	Taxol-derivate
MX9307777A (es)	1992-12-15	1994-07-29	Upjohn Co	7-HALO-Y 7ß, 8ß-METANO-TAXOLES, USO ANTINEOPLASTICO Y COMPOSICIONES FARMACEUTICAS QUE LOS CONTIENEN.
EP0982302B1 (en) *	1993-06-11	2004-04-14	PHARMACIA & UPJOHN COMPANY	Delta 6,7-taxols antineoplastic use and pharmaceutical compositions containing them
IL127599A (en) *	1994-01-28	2004-06-01	Upjohn Co	Process for preparing isotaxol analogs
US5580899A (en) *	1995-01-09	1996-12-03	The Liposome Company, Inc.	Hydrophobic taxane derivatives
US6107332A (en)	1995-09-12	2000-08-22	The Liposome Company, Inc.	Hydrolysis-promoting hydrophobic taxane derivatives
US6051600A (en) *	1995-09-12	2000-04-18	Mayhew; Eric	Liposomal hydrolysis-promoting hydrophobic taxane derivatives
WO2013188763A1 (en)	2012-06-15	2013-12-19	The Brigham And Women's Hospital, Inc.	Compositions for treating cancer and methods for making the same
RU2016140160A (ru)	2014-04-03	2018-05-07	Инвиктус Онколоджи Пвт. Лтд.	Супрамолекулярные комбинаторные лекарственные средства

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CA1108180A (en) *	1976-07-21	1981-09-01	Hamao Umezawa	Analogs of bestatin
FR2629819B1 (fr) *	1988-04-06	1990-11-16	Rhone Poulenc Sante	Procede de preparation de derives de la baccatine iii et de la desacetyl-10 baccatine iii
FR2629818B1 (fr) *	1988-04-06	1990-11-16	Centre Nat Rech Scient	Procede de preparation du taxol
US5175315A (en) *	1989-05-31	1992-12-29	Florida State University	Method for preparation of taxol using β-lactam
FR2662440B1 (fr) *	1990-05-22	1992-07-31	Rhone Poulenc Sante	Procede de preparation stereoselective de derives de la phenylisoserine.
FR2662441B1 (fr) *	1990-05-22	1992-10-23	Rhone Poulenc Sante	Procede de preparation enantioselective de derives de la phenylisoserine.

1990
- 1990-02-21 FR FR9002099A patent/FR2658510B1/fr not_active Expired - Lifetime
1991
- 1991-02-19 IL IL9727791A patent/IL97277A/en not_active IP Right Cessation
- 1991-02-19 ZA ZA911211A patent/ZA911211B/xx unknown
- 1991-02-20 DK DK91905054.2T patent/DK0515540T3/da active
- 1991-02-20 AT AT91905054T patent/ATE108176T1/de not_active IP Right Cessation
- 1991-02-20 SK SK438-91A patent/SK278304B6/sk not_active IP Right Cessation
- 1991-02-20 KR KR1019920701998A patent/KR100197481B1/ko not_active Expired - Lifetime
- 1991-02-20 US US07/920,508 patent/US5359124A/en not_active Expired - Lifetime
- 1991-02-20 CZ CS91438A patent/CZ279656B6/cs not_active IP Right Cessation
- 1991-02-20 CA CA002071983A patent/CA2071983C/fr not_active Expired - Lifetime
- 1991-02-20 HU HU9202667A patent/HU209615B/hu unknown
- 1991-02-20 JP JP3505196A patent/JP3057097B2/ja not_active Expired - Lifetime
- 1991-02-20 RU SU915053004A patent/RU2074172C1/ru active
- 1991-02-20 DE DE69102762T patent/DE69102762T2/de not_active Expired - Lifetime
- 1991-02-20 IE IE58691A patent/IE64397B1/en not_active IP Right Cessation
- 1991-02-20 ES ES91905054T patent/ES2056639T3/es not_active Expired - Lifetime
- 1991-02-20 AU AU73453/91A patent/AU642717B2/en not_active Expired
- 1991-02-20 WO PCT/FR1991/000132 patent/WO1991013053A1/fr not_active Ceased
- 1991-02-20 EP EP91905054A patent/EP0515540B1/fr not_active Expired - Lifetime
- 1991-02-21 PT PT96849A patent/PT96849B/pt not_active IP Right Cessation
- 1991-02-21 YU YU31191A patent/YU48671B/sh unknown
1992
- 1992-08-17 FI FI923679A patent/FI111247B/fi active
- 1992-08-18 NO NO923226A patent/NO179865C/no not_active IP Right Cessation

Also Published As

Publication number	Publication date
ES2056639T3 (es)	1994-10-01
NO923226D0 (no)	1992-08-18
IL97277A (en)	1995-12-08
JPH05504954A (ja)	1993-07-29
FI923679L (fi)	1992-08-17
NO179865C (no)	1997-01-02
ZA911211B (en)	1991-11-27
YU31191A (sh)	1993-11-16
CA2071983A1 (fr)	1991-08-22
IL97277A0 (en)	1992-05-25
FR2658510A1 (fr)	1991-08-23
KR100197481B1 (ko)	1999-06-15
PT96849A (pt)	1991-10-31
FI111247B (fi)	2003-06-30
DE69102762D1 (de)	1994-08-11
US5359124A (en)	1994-10-25
WO1991013053A1 (fr)	1991-09-05
EP0515540A1 (fr)	1992-12-02
AU642717B2 (en)	1993-10-28
CZ279656B6 (cs)	1995-05-17
ATE108176T1 (de)	1994-07-15
HUT61971A (en)	1993-03-29
CS9100438A2 (en)	1991-09-15
YU48671B (sh)	1999-06-15
IE910586A1 (en)	1991-08-28
AU7345391A (en)	1991-09-18
JP3057097B2 (ja)	2000-06-26
FR2658510B1 (fr)	1992-04-30
SK278304B6 (en)	1996-09-04
HU209615B (en)	1994-09-28
EP0515540B1 (fr)	1994-07-06
FI923679A0 (fi)	1992-08-17
DK0515540T3 (da)	1994-08-15
IE64397B1 (en)	1995-08-09
PT96849B (pt)	1998-07-31
RU2074172C1 (ru)	1997-02-27
CA2071983C (fr)	2003-03-18
NO179865B (no)	1996-09-23
KR927003561A (ko)	1992-12-18
DE69102762T2 (de)	1994-10-27
HU9202667D0 (en)	1992-12-28

Legal Events

Date	Code	Title	Description
2011-03-07	MK1K	Patent expired

Publication	Publication Date	Title
DK0554247T3 (da)	2000-08-07	Neurobeskyttende indolon og beslægtede derivater
DK0591333T3 (da)	1997-05-20	Azanorbornanderivater
ATE172968T1 (de)	1998-11-15	Substituierte azadioxacycloalkene und ihre verwendung als fungizide
NO923226D0 (no)	1992-08-18	Nytt beta-fenylisoserinderivat, dets fremstilling og anvendelse
ATE191478T1 (de)	2000-04-15	3,6-disubstituierte-2-fluoropyridine
MX9203100A (es)	1993-07-01	Nuevos peptidos, su preparacion y su aplicacion.
LV11899A (lv)	1997-12-20	Jauni adenozina atvasinajumi to iegusanas panemiens
NO962285L (no)	1996-06-03	N-substituerte azabicykloheptan-derivater anvendt for eksempel som neuroleptika
MX9303605A (es)	1993-12-01	Derivados de azabicicloheptano n-substituidas, su obtencion y uso.
DK0668852T3 (da)	1998-03-16	Substituerede orthoethenylphenyleddikesyrederivater
DK0641346T3 (da)	1996-07-29	Antibiotiske 7-aminonaphthazarinderivater
NO307706B1 (no)	2000-05-15	Substituerte aryltiolalkyltiopyridiner
DK0589903T3 (da)	1999-06-07	Aminoalkylsubstituerede 5-mercaptothiazoler, deres fremstilling og anvendelse
ATE181327T1 (de)	1999-07-15	Indolderivate
NO954316D0 (no)	1995-10-27	Benzo(f)kinoksalidinonderivater, deres fremstilling og anvendelse i legemidler
ATE139773T1 (de)	1996-07-15	Neue 1-aryl-4-piperazinyl- cyclohexancarbonsäurenitrile, ihre herstellung und verwendung
DK0539451T3 (da)	1994-10-24	Vinylsulfonyl-pristinamycin og dets fremstilling