ES2056639T3 - Procedimiento para la transformacion del acido (benzoil-3 fenil)-2 propionico-r(-) en isomero s(+). - Google Patents

Procedimiento para la transformacion del acido (benzoil-3 fenil)-2 propionico-r(-) en isomero s(+).

Info

Publication number
ES2056639T3
ES2056639T3 ES91905054T ES91905054T ES2056639T3 ES 2056639 T3 ES2056639 T3 ES 2056639T3 ES 91905054 T ES91905054 T ES 91905054T ES 91905054 T ES91905054 T ES 91905054T ES 2056639 T3 ES2056639 T3 ES 2056639T3
Authority
ES
Spain
Prior art keywords
propionico
isomero
fenil
benzoil
transformation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES91905054T
Other languages
English (en)
Inventor
Jean-Pierre Duchesne
Michel Mulhauser
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Aventis Pharma SA
Original Assignee
Rhone Poulenc Rorer SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rhone Poulenc Rorer SA filed Critical Rhone Poulenc Rorer SA
Application granted granted Critical
Publication of ES2056639T3 publication Critical patent/ES2056639T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C229/34—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton containing six-membered aromatic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D305/00—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms
    • C07D305/14—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms condensed with carbocyclic rings or ring systems

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Epoxy Compounds (AREA)
  • Liquid Developers In Electrophotography (AREA)
  • Indole Compounds (AREA)

Abstract

NUEVO DERIVADO DE LA BETA-FENILISOSERINA DE FORMULA (I), SU PREPARACION Y SU EMPLEO COMO INTERMEDIARIO EN LA SINTESIS DE TAXOL O DE SUS DERIVADOS.
ES91905054T 1990-02-21 1991-02-20 Procedimiento para la transformacion del acido (benzoil-3 fenil)-2 propionico-r(-) en isomero s(+). Expired - Lifetime ES2056639T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9002099A FR2658510B1 (fr) 1990-02-21 1990-02-21 Nouveau derive de la beta-phenylisoserine, sa preparation et son emploi.

Publications (1)

Publication Number Publication Date
ES2056639T3 true ES2056639T3 (es) 1994-10-01

Family

ID=9393962

Family Applications (1)

Application Number Title Priority Date Filing Date
ES91905054T Expired - Lifetime ES2056639T3 (es) 1990-02-21 1991-02-20 Procedimiento para la transformacion del acido (benzoil-3 fenil)-2 propionico-r(-) en isomero s(+).

Country Status (23)

Country Link
US (1) US5359124A (es)
EP (1) EP0515540B1 (es)
JP (1) JP3057097B2 (es)
KR (1) KR100197481B1 (es)
AT (1) ATE108176T1 (es)
AU (1) AU642717B2 (es)
CA (1) CA2071983C (es)
CZ (1) CZ279656B6 (es)
DE (1) DE69102762T2 (es)
DK (1) DK0515540T3 (es)
ES (1) ES2056639T3 (es)
FI (1) FI111247B (es)
FR (1) FR2658510B1 (es)
HU (1) HU209615B (es)
IE (1) IE64397B1 (es)
IL (1) IL97277A (es)
NO (1) NO179865C (es)
PT (1) PT96849B (es)
RU (1) RU2074172C1 (es)
SK (1) SK278304B6 (es)
WO (1) WO1991013053A1 (es)
YU (1) YU48671B (es)
ZA (1) ZA911211B (es)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5939561A (en) * 1992-03-10 1999-08-17 Rhone-Poulence Rorer S.A. Process for the preparation of β-phenylisoserine and β-lactam and their analogues
FR2688499B1 (fr) * 1992-03-10 1994-05-06 Rhone Poulenc Rorer Sa Procede de preparation de la beta-phenylisoserine et de ses analogues.
DE69325454T2 (de) * 1992-04-17 2000-01-20 Abbott Laboratories, Abbott Park Taxol-derivate
MX9307777A (es) 1992-12-15 1994-07-29 Upjohn Co 7-HALO-Y 7ß, 8ß-METANO-TAXOLES, USO ANTINEOPLASTICO Y COMPOSICIONES FARMACEUTICAS QUE LOS CONTIENEN.
EP0982302B1 (en) * 1993-06-11 2004-04-14 PHARMACIA & UPJOHN COMPANY Delta 6,7-taxols antineoplastic use and pharmaceutical compositions containing them
IL127599A (en) * 1994-01-28 2004-06-01 Upjohn Co Process for preparing isotaxol analogs
US5580899A (en) * 1995-01-09 1996-12-03 The Liposome Company, Inc. Hydrophobic taxane derivatives
US6107332A (en) 1995-09-12 2000-08-22 The Liposome Company, Inc. Hydrolysis-promoting hydrophobic taxane derivatives
US6051600A (en) * 1995-09-12 2000-04-18 Mayhew; Eric Liposomal hydrolysis-promoting hydrophobic taxane derivatives
WO2013188763A1 (en) 2012-06-15 2013-12-19 The Brigham And Women's Hospital, Inc. Compositions for treating cancer and methods for making the same
RU2016140160A (ru) 2014-04-03 2018-05-07 Инвиктус Онколоджи Пвт. Лтд. Супрамолекулярные комбинаторные лекарственные средства

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1108180A (en) * 1976-07-21 1981-09-01 Hamao Umezawa Analogs of bestatin
FR2629819B1 (fr) * 1988-04-06 1990-11-16 Rhone Poulenc Sante Procede de preparation de derives de la baccatine iii et de la desacetyl-10 baccatine iii
FR2629818B1 (fr) * 1988-04-06 1990-11-16 Centre Nat Rech Scient Procede de preparation du taxol
US5175315A (en) * 1989-05-31 1992-12-29 Florida State University Method for preparation of taxol using β-lactam
FR2662440B1 (fr) * 1990-05-22 1992-07-31 Rhone Poulenc Sante Procede de preparation stereoselective de derives de la phenylisoserine.
FR2662441B1 (fr) * 1990-05-22 1992-10-23 Rhone Poulenc Sante Procede de preparation enantioselective de derives de la phenylisoserine.

Also Published As

Publication number Publication date
NO923226D0 (no) 1992-08-18
IL97277A (en) 1995-12-08
JPH05504954A (ja) 1993-07-29
FI923679L (fi) 1992-08-17
NO179865C (no) 1997-01-02
ZA911211B (en) 1991-11-27
YU31191A (sh) 1993-11-16
CA2071983A1 (fr) 1991-08-22
IL97277A0 (en) 1992-05-25
FR2658510A1 (fr) 1991-08-23
KR100197481B1 (ko) 1999-06-15
PT96849A (pt) 1991-10-31
FI111247B (fi) 2003-06-30
NO923226L (no) 1992-08-18
DE69102762D1 (de) 1994-08-11
US5359124A (en) 1994-10-25
WO1991013053A1 (fr) 1991-09-05
EP0515540A1 (fr) 1992-12-02
AU642717B2 (en) 1993-10-28
CZ279656B6 (cs) 1995-05-17
ATE108176T1 (de) 1994-07-15
HUT61971A (en) 1993-03-29
CS9100438A2 (en) 1991-09-15
YU48671B (sh) 1999-06-15
IE910586A1 (en) 1991-08-28
AU7345391A (en) 1991-09-18
JP3057097B2 (ja) 2000-06-26
FR2658510B1 (fr) 1992-04-30
SK278304B6 (en) 1996-09-04
HU209615B (en) 1994-09-28
EP0515540B1 (fr) 1994-07-06
FI923679A0 (fi) 1992-08-17
DK0515540T3 (da) 1994-08-15
IE64397B1 (en) 1995-08-09
PT96849B (pt) 1998-07-31
RU2074172C1 (ru) 1997-02-27
CA2071983C (fr) 2003-03-18
NO179865B (no) 1996-09-23
KR927003561A (ko) 1992-12-18
DE69102762T2 (de) 1994-10-27
HU9202667D0 (en) 1992-12-28

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