PT97436A - Processo para a liofilizacao de uma emulsao de oleo em agua - Google Patents

Processo para a liofilizacao de uma emulsao de oleo em agua Download PDF

Info

Publication number: PT97436A
Authority: PT; Portugal
Prior art keywords: oil; emulsion; agent; hours; water
Prior art date: 1991-04-05

Application number

PT9743691A

Other languages

English (en)

Portuguese (pt)

Inventor

Lodhi Shahid

Chaturvedi Pravin

Original Assignee

Warner-Lambert Co.

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1991-04-05

Filing date

1991-04-22

Publication date

1992-01-31

1991-04-22 Application filed by Warner-Lambert Co. filed Critical Warner-Lambert Co.

1992-01-31 Publication of PT97436A publication Critical patent/PT97436A/pt

Links

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XOFYZVNMUHMLCC-ZPOLXVRWSA-N prednisone Chemical compound O=C1C=C[C@]2(C)[C@H]3C(=O)C[C@](C)([C@@](CC4)(O)C(=O)CO)[C@@H]4[C@@H]3CCC2=C1 XOFYZVNMUHMLCC-ZPOLXVRWSA-N 0.000 description 1
229960004618 prednisone Drugs 0.000 description 1
238000002360 preparation method Methods 0.000 description 1
239000003755 preservative agent Substances 0.000 description 1
239000000583 progesterone congener Substances 0.000 description 1
239000003813 safflower oil Substances 0.000 description 1
235000005713 safflower oil Nutrition 0.000 description 1
229960002060 secobarbital Drugs 0.000 description 1
KQPKPCNLIDLUMF-UHFFFAOYSA-N secobarbital Chemical compound CCCC(C)C1(CC=C)C(=O)NC(=O)NC1=O KQPKPCNLIDLUMF-UHFFFAOYSA-N 0.000 description 1
239000000932 sedative agent Substances 0.000 description 1
230000001624 sedative effect Effects 0.000 description 1
229960003440 semustine Drugs 0.000 description 1
239000007787 solid Substances 0.000 description 1
239000001570 sorbitan monopalmitate Substances 0.000 description 1
235000011071 sorbitan monopalmitate Nutrition 0.000 description 1
229940031953 sorbitan monopalmitate Drugs 0.000 description 1
239000000600 sorbitol Substances 0.000 description 1
238000005507 spraying Methods 0.000 description 1
239000008223 sterile water Substances 0.000 description 1
230000001954 sterilising effect Effects 0.000 description 1
238000004659 sterilization and disinfection Methods 0.000 description 1
238000003756 stirring Methods 0.000 description 1
ZSJLQEPLLKMAKR-GKHCUFPYSA-N streptozocin Chemical compound O=NN(C)C(=O)N[C@H]1[C@@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O ZSJLQEPLLKMAKR-GKHCUFPYSA-N 0.000 description 1
229960001052 streptozocin Drugs 0.000 description 1
235000010384 tocopherol Nutrition 0.000 description 1
229960001295 tocopherol Drugs 0.000 description 1
229930003799 tocopherol Natural products 0.000 description 1
239000011732 tocopherol Substances 0.000 description 1
NOYPYLRCIDNJJB-UHFFFAOYSA-N trimetrexate Chemical compound COC1=C(OC)C(OC)=CC(NCC=2C(=C3C(N)=NC(N)=NC3=CC=2)C)=C1 NOYPYLRCIDNJJB-UHFFFAOYSA-N 0.000 description 1
229960001099 trimetrexate Drugs 0.000 description 1
235000015112 vegetable and seed oil Nutrition 0.000 description 1
239000008158 vegetable oil Substances 0.000 description 1
229960003636 vidarabine Drugs 0.000 description 1
229920003169 water-soluble polymer Polymers 0.000 description 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Epidemiology (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Dispersion Chemistry (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Medicinal Preparation (AREA)

PT9743691A 1991-04-05 1991-04-22 Processo para a liofilizacao de uma emulsao de oleo em agua PT97436A (pt)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
PCT/US1991/002353 WO1992017162A1 (fr)	1991-04-05	1991-04-05	Emulsion lyophilisee

Publications (1)

Publication Number	Publication Date
PT97436A true PT97436A (pt)	1992-01-31

Family

ID=22225440

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
PT9743691A PT97436A (pt)	1991-04-05	1991-04-22	Processo para a liofilizacao de uma emulsao de oleo em agua

Country Status (2)

Country	Link
PT (1)	PT97436A (fr)
WO (1)	WO1992017162A1 (fr)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE4244122C1 (de) *	1992-12-24	1994-06-01	Sanol Arznei Schwarz Gmbh	Lyophilisierte, wirkstoffhaltige Emulsion zur intravenösen Applikation
US5851510A (en) *	1994-05-16	1998-12-22	The Board Of Regents Of The University Of Michigan	Hepatocyte-selective oil-in-water emulsion
US6383471B1 (en) *	1999-04-06	2002-05-07	Lipocine, Inc.	Compositions and methods for improved delivery of ionizable hydrophobic therapeutic agents
ZA201602963B (en) *	2015-05-07	2017-07-26	Csir	Method for encapsulating pharmaceutical actives
CN110573142B (zh) *	2017-10-25	2024-01-16	费森尤斯卡比德国有限公司	用于胃肠外应用的多合一冻干复合维生素乳剂

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FR2561916B1 (fr) *	1984-03-30	1987-12-11	Lafon Labor	Forme galenique pour administration orale et son procede de preparation par lyophilisation d'une emission huile dans eau
IL78930A0 (en) *	1985-07-29	1986-09-30	Abbott Lab	Lyophilized emulsion compositions for parenteral administration

1991
- 1991-04-05 WO PCT/US1991/002353 patent/WO1992017162A1/fr not_active Ceased
- 1991-04-22 PT PT9743691A patent/PT97436A/pt not_active Application Discontinuation

Also Published As

Publication number	Publication date
WO1992017162A1 (fr)	1992-10-15

Legal Events

Date	Code	Title	Description
1992-01-31	BB1A	Laying open of patent application	Effective date: 19910912
1998-08-31	FC3A	Refusal	Effective date: 19980511

Publication	Publication Date	Title
US8211948B2 (en)	2012-07-03	Lyophilized nanoemulsion
US4743449A (en)	1988-05-10	Drug-containing lipid vesicle preparation and method for preparing them
US5750142A (en)	1998-05-12	Dry compositions for preparing submicron emulsions
AU730216B2 (en)	2001-03-01	Solid coprecipitates for enhanced bioavailability of lipophilic substances
CA2194226C (fr)	2000-10-24	Emulsions stables huile-dans-eau incorporant une taxine (taxol) et procede de preparation
US5891469A (en)	1999-04-06	Solid Coprecipitates for enhanced bioavailability of lipophilic substances
AU767896B2 (en)	2003-11-27	Use of nanodispersions in pharmaceutical end formulations
EP0171084A2 (fr)	1986-02-12	Micro-émulsions pharmaceutiques du type huile-dans-eau
DE69331930T2 (de)	2003-01-09	Trockene zusammensetzungen zur herstellung von emulsionen im submikron-bereich
FR2561916A1 (fr)	1985-10-04	Forme galenique pour administration orale et son procede de preparation par lyophilisation d'une emission huile dans eau
HU180792B (en)	1983-04-29	Process for producing water-containing compositions
MX2011000795A (es)	2011-03-29	Nanoemulsion estable inyectable de docetaxel de aceite en agua.
JPH08511245A (ja)	1996-11-26	薬剤搬送ビヒクルとしての固体脂肪ナノエマルジョン体
NL8802657A (nl)	1989-05-16	Geneesmiddeldragers.
JPS6229513A (ja)	1987-02-07	凍結乾燥したエマルジヨン組成物およびその方法
PT99113B (pt)	1999-02-26	Processo para a preparacao de matrizes que originam particulas de lipidos
HK83293A (en)	1993-08-20	Composition of pregnanolole comprising a stable oil-in-water emulsion
JPH02203A (ja)	1990-01-05	薬物担体
BR112018009250B1 (pt)	2023-12-05	Formulações aperfeiçoadas de levosimendana para administração intravenosa por infusão ou injeção e de concentrados para infusão
PT1565163E (pt)	2012-05-08	Concentrados hidrossolúveis do tipo emulsão
US4976964A (en)	1990-12-11	Medicament formulation containing dihydropyridines and a process for its preparation
JP5497336B2 (ja)	2014-05-21	薬物を保持した脂肪粒子を含む非水系組成物およびその製造方法
PT97436A (pt)	1992-01-31	Processo para a liofilizacao de uma emulsao de oleo em agua
CN101524329B (zh)	2014-09-03	双环醇亚微乳及其制备方法
CA1249223A (fr)	1989-01-24	Formulations de medicaments solides et suspensions stables