PT97468A - Processo para a preparacao de suspensoes aquosas de lipossomas contendo em especial derivados iodados ou complexos de gadolinio - Google Patents

Processo para a preparacao de suspensoes aquosas de lipossomas contendo em especial derivados iodados ou complexos de gadolinio

Info

Publication number: PT97468A
Authority: PT; Portugal
Prior art keywords: preparation; gadolinio; iodate; complexes; derivatives
Prior art date: 1990-04-24

Application number

PT97468A

Other languages

English (en)

Other versions

PT97468B (pt

Inventor

Georg Roessling

Andreas Schase

Hans-Joachim Schroter

Claudia Sprenger

Cornelia Wawretschek

Original Assignee

Schering Ag

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1990-04-24

Filing date

1991-04-24

Publication date

1992-01-31

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=6405285&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PT97468(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

1991-04-24 Application filed by Schering Ag filed Critical Schering Ag

1992-01-31 Publication of PT97468A publication Critical patent/PT97468A/pt

1999-12-31 Publication of PT97468B publication Critical patent/PT97468B/pt

Links

239000002502 liposome Substances 0.000 title abstract 3
238000000034 method Methods 0.000 title abstract 3
238000002360 preparation method Methods 0.000 title abstract 2
239000007900 aqueous suspension Substances 0.000 title 1
UIWYJDYFSGRHKR-UHFFFAOYSA-N gadolinium atom Chemical class [Gd] UIWYJDYFSGRHKR-UHFFFAOYSA-N 0.000 title 1
ICIWUVCWSCSTAQ-UHFFFAOYSA-N iodic acid Chemical class OI(=O)=O ICIWUVCWSCSTAQ-UHFFFAOYSA-N 0.000 title 1
239000008346 aqueous phase Substances 0.000 abstract 3
239000000725 suspension Substances 0.000 abstract 3
LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 abstract 2
239000000126 substance Substances 0.000 abstract 2
239000004480 active ingredient Substances 0.000 abstract 1
239000013543 active substance Substances 0.000 abstract 1
230000001476 alcoholic effect Effects 0.000 abstract 1
125000004432 carbon atom Chemical group C* 0.000 abstract 1
150000002632 lipids Chemical class 0.000 abstract 1
239000000203 mixture Substances 0.000 abstract 1
238000005292 vacuum distillation Methods 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
- A61K9/1277—Preparation processes; Proliposomes

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Veterinary Medicine (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Epidemiology (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Dispersion Chemistry (AREA)
Medicinal Preparation (AREA)
Manufacturing Of Micro-Capsules (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Steroid Compounds (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Cosmetics (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Agricultural Chemicals And Associated Chemicals (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

PT97468A 1990-04-24 1991-04-24 Processo para a preparacao de suspensoes aquosas de lipossomas contendo em especial derivados iodados ou complexos de gadolinio PT97468B (pt)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
DE4013580A DE4013580A1 (de)	1990-04-24	1990-04-24	Verfahren zur herstellung von wirkstoffhaltigen waessrigen liposomensuspensionen

Publications (2)

Publication Number	Publication Date
PT97468A true PT97468A (pt)	1992-01-31
PT97468B PT97468B (pt)	1999-12-31

Family

ID=6405285

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
PT97468A PT97468B (pt)	1990-04-24	1991-04-24	Processo para a preparacao de suspensoes aquosas de lipossomas contendo em especial derivados iodados ou complexos de gadolinio

Country Status (15)

Country	Link
EP (1)	EP0478727B1 (pt)
JP (1)	JPH04506814A (pt)
AT (1)	ATE141503T1 (pt)
AU (1)	AU651969B2 (pt)
CA (1)	CA2041075A1 (pt)
DE (2)	DE4013580A1 (pt)
DK (1)	DK0478727T3 (pt)
ES (1)	ES2093701T3 (pt)
FI (1)	FI103178B1 (pt)
HU (1)	HU215960B (pt)
IE (1)	IE911350A1 (pt)
NO (1)	NO303481B1 (pt)
PT (1)	PT97468B (pt)
WO (1)	WO1991016039A1 (pt)
ZA (1)	ZA913091B (pt)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JP3299745B2 (ja) *	1991-06-18	2002-07-08	イマアーレクス・フアーマシユーチカル・コーポレーシヨン	新規なリポソーム薬配達システム
EP0713387B1 (en) *	1993-08-06	1998-03-04	Opperbas Holding B.V.	A method for preparation of vesicles loaded with biological structures, biopolymers and/or oligomers
ZA952485B (en) *	1994-03-28	1995-12-15	Nycomed Imaging As	Liposomes
AU2066897A (en) *	1996-03-27	1997-10-17	Ortho Pharmaceutical Corporation	Manufacture of liposomes and lipid-protein complexes by ethanolic injection and thin film evaporation
RU2134967C1 (ru) *	1997-05-30	1999-08-27	Шестаков Константин Алексеевич	Способ получения микрокапсулированных препаратов, содержащих пиретроидные инсектициды
EP1150658B1 (en) *	1999-02-08	2004-08-04	Alza Corporation	Method for controlling liposome size
EP1519714B1 (en) *	2002-06-28	2010-10-20	Protiva Biotherapeutics Inc.	Method and apparatus for producing liposomes
CN103989633A (zh)	2005-07-27	2014-08-20	普洛体维生物治疗公司	制造脂质体的系统和方法
US12491261B2 (en)	2016-10-26	2025-12-09	Acuitas Therapeutics, Inc.	Lipid nanoparticle formulations
JP7798855B2 (ja)	2020-07-16	2026-01-14	アクイタスセラピューティクスインコーポレイテッド	脂質ナノ粒子に使用するためのカチオン性脂質
CA3242402A1 (en)	2021-12-16	2023-06-22	Acuitas Therapeutics, Inc.	Lipids for use in lipid nanoparticle formulations
CN114344291B (zh) *	2022-02-16	2023-09-29	中南大学湘雅医院	4-苯基-1h-吡咯-3-羧酸在制备治疗骨质疏松药物中的应用、脂质体

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE3416978A1 (de) *	1983-05-12	1984-12-06	Stauffer Chemical Co., Westport, Conn.	Durch liposom vermittelte transformation eukaryotischer zellen
JPS607932A (ja) *	1983-06-29	1985-01-16	Dai Ichi Seiyaku Co Ltd	リポソーム懸濁液およびその製法
EP0158441B2 (en) *	1984-03-08	2001-04-04	Phares Pharmaceutical Research N.V.	Liposome-forming composition
FR2634375B3 (fr) *	1988-06-30	1991-07-05	Centre Nat Rech Scient	Procede de preparation de systemes colloidaux dispersibles de lipide amphiphiles sous forme de liposomes submicroniques
JP2554880B2 (ja) *	1987-05-07	1996-11-20	ポーラ化成工業株式会社	皮膚化粧料

1990
- 1990-04-24 DE DE4013580A patent/DE4013580A1/de not_active Withdrawn
1991
- 1991-04-04 DE DE59108097T patent/DE59108097D1/de not_active Expired - Fee Related
- 1991-04-04 DK DK91906756.1T patent/DK0478727T3/da active
- 1991-04-04 ES ES91906756T patent/ES2093701T3/es not_active Expired - Lifetime
- 1991-04-04 WO PCT/DE1991/000294 patent/WO1991016039A1/de not_active Ceased
- 1991-04-04 JP JP3506736A patent/JPH04506814A/ja active Pending
- 1991-04-04 EP EP91906756A patent/EP0478727B1/de not_active Expired - Lifetime
- 1991-04-04 AT AT91906756T patent/ATE141503T1/de not_active IP Right Cessation
- 1991-04-04 HU HU9200235A patent/HU215960B/hu not_active IP Right Cessation
- 1991-04-23 IE IE135091A patent/IE911350A1/en unknown
- 1991-04-24 CA CA002041075A patent/CA2041075A1/en not_active Abandoned
- 1991-04-24 ZA ZA913091A patent/ZA913091B/xx unknown
- 1991-04-24 AU AU75933/91A patent/AU651969B2/en not_active Ceased
- 1991-04-24 PT PT97468A patent/PT97468B/pt not_active IP Right Cessation
- 1991-12-18 NO NO915012A patent/NO303481B1/no unknown
- 1991-12-23 FI FI916120A patent/FI103178B1/fi active

Also Published As

Publication number	Publication date
HU215960B (hu)	1999-03-29
AU651969B2 (en)	1994-08-11
NO303481B1 (no)	1998-07-20
WO1991016039A1 (de)	1991-10-31
ZA913091B (en)	1992-12-30
FI103178B (fi)	1999-05-14
IE911350A1 (en)	1991-11-06
DK0478727T3 (pt)	1997-01-20
FI916120A0 (fi)	1991-12-23
EP0478727A1 (de)	1992-04-08
NO915012L (no)	1991-12-18
CA2041075A1 (en)	1991-10-25
HU9200235D0 (en)	1992-04-28
ES2093701T3 (es)	1997-01-01
DE4013580A1 (de)	1991-10-31
NO915012D0 (no)	1991-12-18
JPH04506814A (ja)	1992-11-26
PT97468B (pt)	1999-12-31
HUT62457A (en)	1993-05-28
EP0478727B1 (de)	1996-08-21
AU7593391A (en)	1991-11-07
DE59108097D1 (de)	1996-09-26
FI103178B1 (fi)	1999-05-14
ATE141503T1 (de)	1996-09-15

Legal Events

Date	Code	Title	Description
1992-01-31	BB1A	Laying open of patent application	Effective date: 19910930
1999-12-31	FG3A	Patent granted, date of granting	Effective date: 19990928
2001-04-30	PC3A	Transfer or assignment	Free format text: 20010109 ANDREAS SACHSE DE
2001-07-31	MM3A	Annulment or lapse	Free format text: LAPSE DUE TO NON-PAYMENT OF FEES Effective date: 20010331

Publication	Publication Date	Title
ES8607906A1 (es)	1986-06-01	Procedimiento para la obtencion de composiciones farmaceuti-cas conteniendo liposomas unilamilares
AU551241B2 (en)	1986-04-24	Preparation of liposomal medicaments
US4308166A (en)	1981-12-29	Process for the extemporaneous preparation of liposomes
ATE52411T1 (de)	1990-05-15	Zubereitung von arzneimittelhaltigen lipidvesikeln und verfahren zu deren herstellung.
NO172729C (no)	1993-09-01	Fremgangsmaate for fremstilling av en suspensjon av fosfolipidvesikler.
AU588688B2 (en)	1989-09-21	For facilitating the formation of lipid spherules dispersed in an aqueous phase and for improving their stability and their degree of encapsulation, and corresponding dispersions
CA2138925A1 (en)	1995-07-01	Method of producing reconstituted lipoproteins
AU8141791A (en)	1991-11-07	Method for determining unentrapped ionizable bioactive agents in liposome preparations
SE8206168D0 (sv)	1982-10-29	Preparations and process for preparation thereof
DK0478727T3 (pt)	1997-01-20
ES2078510T3 (es)	1995-12-16	Dispersion acuosa de vesiculas de fosfolipidos, procedimiento para su fabricacion y su uso.
GR3007265T3 (en)	1993-07-30	Process for the preparation of dispersible colloidal systems of amphiphilic lipids in the form of submicronic liposomes
CA2117769A1 (en)	1993-10-11	Liposome composition
NO913816D0 (no)	1991-09-27	Fremstilling av liposom- og lipidkompleksblandinger.
KR920002165A (ko)	1992-02-28	리포좀 생성물
EP0198765A3 (en)	1987-10-21	Preparation of liposomes
DE3878696D1 (de)	1993-04-01	Liposome, ihre herstellung und anwendung als vektor von arzneimitteln.
KR920002166A (ko)	1992-02-28	주사용 리포좀 분산제를 제조하는 방법
ES2129342A1 (es)	1999-06-01	"formulacion de vacunas liposomales y su preparacion".
TH20467A (th)	1996-09-10	ดีโทโฟรเฟนไลโปโซม