PT97953A - Processo para a preparacao industrial da 4-cloro-3-sulfamoil-n-(2,3-di-hidro-2-metil-1h-1-indolil)-benzamida - Google Patents

Processo para a preparacao industrial da 4-cloro-3-sulfamoil-n-(2,3-di-hidro-2-metil-1h-1-indolil)-benzamida

Info

Publication number
PT97953A
PT97953A PT97953A PT9795391A PT97953A PT 97953 A PT97953 A PT 97953A PT 97953 A PT97953 A PT 97953A PT 9795391 A PT9795391 A PT 9795391A PT 97953 A PT97953 A PT 97953A
Authority
PT
Portugal
Prior art keywords
dihydro
methyl
benzamide
chloro
sulfamoyl
Prior art date
Application number
PT97953A
Other languages
English (en)
Other versions
PT97953B (pt
Inventor
Armand Cohen
Original Assignee
Adir
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Adir filed Critical Adir
Publication of PT97953A publication Critical patent/PT97953A/pt
Publication of PT97953B publication Critical patent/PT97953B/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/08—Indoles; Hydrogenated indoles with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to carbon atoms of the hetero ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Indole Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
PT97953A 1990-06-14 1991-06-12 Processo para a preparacao industrial da 4-cloro-3-sulfamoil-n-(2,3-di-hidro-2-metil-1h-1-indolil)-benzamida PT97953B (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9007386A FR2663324B1 (fr) 1990-06-14 1990-06-14 Nouveau procede de preparation industrielle du 4-chloro 3-sulfamoyl n-(2,3-dihydro 2-methyl 1h-indol-1-yl) benzamide.

Publications (2)

Publication Number Publication Date
PT97953A true PT97953A (pt) 1992-03-31
PT97953B PT97953B (pt) 1998-11-30

Family

ID=9397579

Family Applications (1)

Application Number Title Priority Date Filing Date
PT97953A PT97953B (pt) 1990-06-14 1991-06-12 Processo para a preparacao industrial da 4-cloro-3-sulfamoil-n-(2,3-di-hidro-2-metil-1h-1-indolil)-benzamida

Country Status (16)

Country Link
US (1) US5101040A (pt)
EP (1) EP0462016B1 (pt)
JP (1) JPH04279565A (pt)
AT (1) ATE185137T1 (pt)
AU (1) AU630815B1 (pt)
CA (1) CA2044491C (pt)
DE (1) DE69131657T2 (pt)
DK (1) DK0462016T3 (pt)
ES (1) ES2139573T3 (pt)
FR (1) FR2663324B1 (pt)
GR (1) GR3031339T3 (pt)
IE (1) IE912004A1 (pt)
NZ (1) NZ238526A (pt)
OA (1) OA09365A (pt)
PT (1) PT97953B (pt)
ZA (1) ZA914567B (pt)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2769016B1 (fr) 1997-09-30 1999-10-29 Adir Procede de synthese de chloramine haute teneur
FR2864081B1 (fr) * 2003-12-17 2006-04-28 Isochem Sa Procede de synthese de derives de cycloalkyl-hydrazines exocycliques et de derives d'heterocycloalkyl-hydrazines exocycliques.
FR2864078B1 (fr) * 2003-12-17 2006-02-10 Isochem Sa Procede de synthese en continu de monoalkyl hydrazines a groupe alkyle fonctionnalise
CN100422146C (zh) * 2006-09-25 2008-10-01 天津力生制药股份有限公司 一种吲达帕胺的合成方法
US20080156740A1 (en) * 2006-12-29 2008-07-03 Amit Gupta Method for producing a stable oxidizing biocide
CN101717359B (zh) * 2009-07-15 2012-09-05 北京成宇药业有限公司 吲达帕胺的合成方法
US8532826B2 (en) * 2010-03-10 2013-09-10 Dell Product L.P. System and method for controlling temperature in an information handling system
US9020656B2 (en) 2012-03-27 2015-04-28 Dell Products L.P. Information handling system thermal control by energy conservation
CN103467355A (zh) * 2013-09-12 2013-12-25 迪沙药业集团有限公司 一种吲达帕胺的制备方法
US10136558B2 (en) 2014-07-30 2018-11-20 Dell Products L.P. Information handling system thermal management enhanced by estimated energy states
CN105418479A (zh) * 2015-11-18 2016-03-23 天津市亨必达化学合成物有限公司 一种吲达帕胺的合成方法
EP4559899B1 (en) 2023-11-21 2026-04-01 KRKA, d.d., Novo mesto Synthesis of 1-amino-2-methyl-2,3-dihydroindole by nitrosating 2-methyl-2,3-dihydro-1h-indole and then reducing the obtained 1-nitroso-2-methyl-2,3-dihydroindole with thiourea dioxide

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1095040A (en) * 1966-04-01 1967-12-13 Fmc Corp Hydrazine derivatives
GB1203691A (en) * 1968-03-06 1970-09-03 Science Union & Cie New disubstituted n-amino indoline derivatives and process for preparing them
US3676480A (en) * 1970-02-24 1972-07-11 Merck & Co Inc {60 -acylhydrazino-{62 -phenyl-propionitriles
US4570001A (en) * 1980-12-22 1986-02-11 Science Union Et Cie Process for synthesizing certain N-benzoylamino indolines
DE3172386D1 (en) * 1980-12-22 1985-10-24 Usv Pharma Corp Synthesis of indolines
JPS57206657A (en) * 1981-06-16 1982-12-18 Mitsui Toatsu Chem Inc Sulfamoylbenzoic acid derivative and remedying composition containing said derivative as active component
JPH0233030B2 (ja) * 1982-01-18 1990-07-25 Mitsui Toatsu Chemicals Surufuamoiruansokukosanjudotaioyobisoreojukoseibuntoshitefukumuchiryoyososeibutsu
JPS58124767A (ja) * 1982-01-21 1983-07-25 Mitsui Toatsu Chem Inc スルファモイル安息香酸誘導体
US4564677A (en) * 1984-01-19 1986-01-14 Usv Pharmaceutical Corp. Preparation of N-amino compounds
FR2663325B1 (fr) * 1990-06-14 1992-09-04 Adir Nouveau procede de preparation industrielle du 4-chloro 3-sulfamoyl n-(2,3-dihydro 2-methyl 1h-indol-1-yl) benzamide a partir de la 2,3-dihydro 2-methyl 1h-indole et de l'acide hydroxylamine-o-sulfonique.

Also Published As

Publication number Publication date
OA09365A (fr) 1992-09-15
IE912004A1 (en) 1991-12-18
CA2044491C (fr) 1999-04-13
US5101040A (en) 1992-03-31
ZA914567B (en) 1992-03-25
EP0462016B1 (fr) 1999-09-29
NZ238526A (en) 1992-05-26
DE69131657D1 (de) 1999-11-04
ES2139573T3 (es) 2000-02-16
EP0462016A1 (fr) 1991-12-18
DE69131657T2 (de) 2000-05-11
JPH04279565A (ja) 1992-10-05
AU630815B1 (en) 1992-11-05
DK0462016T3 (da) 2000-03-27
PT97953B (pt) 1998-11-30
FR2663324B1 (fr) 1992-09-04
GR3031339T3 (en) 1999-12-31
ATE185137T1 (de) 1999-10-15
FR2663324A1 (fr) 1991-12-20
CA2044491A1 (fr) 1991-12-15

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Legal Events

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BB1A Laying open of patent application

Effective date: 19911115

FG3A Patent granted, date of granting

Effective date: 19980803

PC3A Transfer or assignment

Free format text: 20011105 LES LABORATOIRES SERVIER FR

MM4A Annulment/lapse due to non-payment of fees, searched and examined patent

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Effective date: 20130805