PT99251A - Processo para a preparacao de derivados de piperazina - Google Patents

Processo para a preparacao de derivados de piperazina

Info

Publication number: PT99251A
Authority: PT; Portugal
Prior art keywords: preparation; piperazine derivatives; rsqbstr; lsqbstr; phenylbutyryl
Prior art date: 1990-10-19

Application number

PT99251A

Other languages

English (en)

Other versions

PT99251B (pt

Inventor

Ian Anthony Cliffe

Original Assignee

Wyeth John & Brother Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1990-10-19

Filing date

1991-10-17

Publication date

1992-08-31

1991-10-17 Application filed by Wyeth John & Brother Ltd filed Critical Wyeth John & Brother Ltd

1992-08-31 Publication of PT99251A publication Critical patent/PT99251A/pt

1999-04-30 Publication of PT99251B publication Critical patent/PT99251B/pt

Links

GLUUGHFHXGJENI-UHFFFAOYSA-N Piperazine Chemical class C1CNCCN1 GLUUGHFHXGJENI-UHFFFAOYSA-N 0.000 title 1
229940066771 systemic antihistamines piperazine derivative Drugs 0.000 title 1
102100022738 5-hydroxytryptamine receptor 1A Human genes 0.000 abstract 1
101710138638 5-hydroxytryptamine receptor 1A Proteins 0.000 abstract 1
239000002253 acid Substances 0.000 abstract 1
239000002249 anxiolytic agent Substances 0.000 abstract 1
230000000949 anxiolytic effect Effects 0.000 abstract 1
229940005530 anxiolytics Drugs 0.000 abstract 1
239000011230 binding agent Substances 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
- C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
- C07D295/182—Radicals derived from carboxylic acids
- C07D295/185—Radicals derived from carboxylic acids from aliphatic carboxylic acids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Veterinary Medicine (AREA)
Life Sciences & Earth Sciences (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Bioinformatics & Cheminformatics (AREA)
Pharmacology & Pharmacy (AREA)
Chemical Kinetics & Catalysis (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Engineering & Computer Science (AREA)
Neurosurgery (AREA)
Neurology (AREA)
Biomedical Technology (AREA)
Heart & Thoracic Surgery (AREA)
Cardiology (AREA)
Anesthesiology (AREA)
Pain & Pain Management (AREA)
Psychiatry (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Pyridine Compounds (AREA)
Other In-Based Heterocyclic Compounds (AREA)
Hydrogenated Pyridines (AREA)
Polymers With Sulfur, Phosphorus Or Metals In The Main Chain (AREA)
Indole Compounds (AREA)

PT99251A 1990-10-19 1991-10-17 Processo para a preparacao de derivados de piperazina PT99251B (pt)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
GB909022820A GB9022820D0 (en)	1990-10-19	1990-10-19	Piperazine derivatives

Publications (2)

Publication Number	Publication Date
PT99251A true PT99251A (pt)	1992-08-31
PT99251B PT99251B (pt)	1999-04-30

Family

ID=10684053

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
PT99251A PT99251B (pt)	1990-10-19	1991-10-17	Processo para a preparacao de derivados de piperazina

Country Status (15)

Country	Link
EP (1)	EP0481744B1 (pt)
JP (1)	JP3007203B2 (pt)
KR (1)	KR100193928B1 (pt)
AT (1)	ATE143012T1 (pt)
AU (1)	AU642044B2 (pt)
CA (1)	CA2053709C (pt)
DE (1)	DE69122205T2 (pt)
DK (1)	DK0481744T3 (pt)
ES (1)	ES2091879T3 (pt)
GB (2)	GB9022820D0 (pt)
GR (1)	GR3021221T3 (pt)
HU (2)	HU212943B (pt)
IE (1)	IE65379B1 (pt)
NZ (1)	NZ240271A (pt)
PT (1)	PT99251B (pt)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB9125900D0 (en) *	1991-12-05	1992-02-05	Wyeth John & Brother Ltd	Piperazine derivatives
JPH08501287A (ja) *	1992-08-05	1996-02-13	ジョン・ワイス・アンド・ブラザー・リミテッド	アミド誘導体
GB9221931D0 (en) *	1992-10-17	1992-12-02	Wyeth John & Brother Ltd	Piperazine derivatives
GB2271930B (en) *	1992-11-03	1996-07-24	Wyeth John & Brother Ltd	Pharmaceutical piperazine derivatives
GB9223153D0 (en) *	1992-11-05	1992-12-16	Wyeth John & Brother Ltd	Piperazine derivatives
GB9303968D0 (en) *	1993-02-26	1993-04-14	Wyeth John & Brother Ltd	5-ht1a ligands
GB9304632D0 (en) *	1993-03-06	1993-04-21	Wyeth John & Brother Ltd	Amide derivatives
US5609849A (en) *	1994-03-11	1997-03-11	The Trustees Of The University Of Pennsylvania	Serotonin (5-HT1A) receptor ligands and imaging agents
GB9419024D0 (en) *	1994-09-21	1994-11-09	Wyeth John & Brother Ltd	Bicyclic carboxamides
GB9525239D0 (en) *	1995-12-09	1996-02-07	American Home Prod	Medical treatment
FR2744448B1 (fr) *	1996-02-02	1998-04-24	Pf Medicament	Nouvelles piperidines derivees d'aryl piperazine, ainsi que leur procede de preparation, les compositions pharmaceutiques et leur utilisation comme medicaments
US5990114A (en) *	1996-02-28	1999-11-23	Recordati, S.A., Chemical And Pharmaceutical Company	Use of 5-HT1A receptor antagonists for the treatment of urinary incontinence
ITMI20021327A1 (it) *	2002-06-14	2003-12-15	Recordati Chem Pharm	Nuove ossialchilpiperazine

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US2776282A (en) *	1954-05-04	1957-01-01	Searle & Co	Cyclic amides of alpha-toluic acids and derivatives thereof
GB8909209D0 (en) *	1989-04-22	1989-06-07	Wyeth John & Brother Ltd	Piperazine derivatives
IL94151A (en) *	1989-04-22	1995-08-31	Wyeth John & Brother Ltd	History of piperazine, their preparation and pharmaceutical preparations containing them
AU644488B2 (en) *	1990-10-19	1993-12-09	John Wyeth & Brother Limited	Piperazine derivatives

1990
- 1990-10-19 GB GB909022820A patent/GB9022820D0/en active Pending
1991
- 1991-09-02 GB GB9118744A patent/GB2248836B/en not_active Expired - Fee Related
- 1991-10-16 ES ES91309513T patent/ES2091879T3/es not_active Expired - Lifetime
- 1991-10-16 AT AT91309513T patent/ATE143012T1/de not_active IP Right Cessation
- 1991-10-16 DE DE69122205T patent/DE69122205T2/de not_active Expired - Fee Related
- 1991-10-16 DK DK91309513.9T patent/DK0481744T3/da active
- 1991-10-16 EP EP91309513A patent/EP0481744B1/en not_active Expired - Lifetime
- 1991-10-17 AU AU85920/91A patent/AU642044B2/en not_active Ceased
- 1991-10-17 JP JP3269290A patent/JP3007203B2/ja not_active Expired - Fee Related
- 1991-10-17 NZ NZ240271A patent/NZ240271A/xx unknown
- 1991-10-17 PT PT99251A patent/PT99251B/pt active IP Right Grant
- 1991-10-18 HU HU913292A patent/HU212943B/hu not_active IP Right Cessation
- 1991-10-18 CA CA002053709A patent/CA2053709C/en not_active Expired - Fee Related
- 1991-10-18 IE IE366991A patent/IE65379B1/en not_active IP Right Cessation
- 1991-10-18 KR KR1019910018373A patent/KR100193928B1/ko not_active Expired - Fee Related
1995
- 1995-06-27 HU HU95P/P00447P patent/HU211587A9/hu unknown
1996
- 1996-10-02 GR GR960402575T patent/GR3021221T3/el unknown

Also Published As

Publication number	Publication date
GB2248836B (en)	1994-05-04
HUT60264A (en)	1992-08-28
EP0481744B1 (en)	1996-09-18
ES2091879T3 (es)	1996-11-16
CA2053709C (en)	2001-12-11
DE69122205T2 (de)	1997-01-30
IE913669A1 (en)	1992-04-22
EP0481744A1 (en)	1992-04-22
KR920008019A (ko)	1992-05-27
HU913292D0 (en)	1992-01-28
AU8592091A (en)	1992-04-30
HU212943B (en)	1996-12-30
DK0481744T3 (da)	1996-10-07
CA2053709A1 (en)	1992-04-20
JP3007203B2 (ja)	2000-02-07
KR100193928B1 (ko)	1999-06-15
GB9118744D0 (en)	1991-10-16
NZ240271A (en)	1993-03-26
IE65379B1 (en)	1995-10-18
DE69122205D1 (de)	1996-10-24
HU211587A9 (en)	1995-12-28
PT99251B (pt)	1999-04-30
GB9022820D0 (en)	1990-12-05
GR3021221T3 (en)	1997-01-31
AU642044B2 (en)	1993-10-07
GB2248836A (en)	1992-04-22
ATE143012T1 (de)	1996-10-15
JPH04282371A (ja)	1992-10-07

Legal Events

Date	Code	Title	Description
1992-08-31	BB1A	Laying open of patent application	Effective date: 19920422
1999-04-30	FG3A	Patent granted, date of granting	Effective date: 19990105

Publication	Publication Date	Title
PT99251A (pt)	1992-08-31	Processo para a preparacao de derivados de piperazina
FI954874A0 (fi)	1995-10-13	Amino(tio)eetterijohdannaisia
ATE138921T1 (de)	1996-06-15	Xanthinderivate
HUT45503A (en)	1988-07-28	Process for producing alpha-alkyl-(4-amino-3-quinolinyl)-methanols, 1-/4-(aralkyl-amino)-3-quinolinyl/-alkanones and pharmaceutics comprising these compounds as active ingredient
ATE113282T1 (de)	1994-11-15	Heteroaryl piperazine als antipsychotische mittel.
PT102145B (pt)	2002-06-28	Composicoes farmaceuticas a base de derivados de piperazina acetamida
ATE110365T1 (de)	1994-09-15	2-alkyl-4-arylmethylaminochinoline, ihre verwendung und daraus hergestellte arzneimittel.
ES2099703T3 (es)	1997-06-01	Derivados de piridina.
NZ216750A (en)	1988-11-29	Morpholino derivatives and fungicides
DE69422532D1 (de)	2000-02-17	2-[4-(4-Azolylbutyl)-1-piperazinyl]-5-hydroxypyrimidin-Derivate, deren Herstellung und deren Verwendung als Heilmittel
ATE139523T1 (de)	1996-07-15	Neue verbindungen und deren medizinale verwendung
MX9205186A (es)	1993-03-01	Derivados de 4-[4-[4-(4-hidroxifenil)-1-piperazinil]-fenil]-5-metil-3h-1,2,4-triazo l-3-ona
NO930284D0 (no)	1993-01-28	Pyridinderivater, fremgangsmaate for deres fremstilling oganvendelse derav
MY110446A (en)	1998-05-30	Piperazine derivatives
MX9201297A (es)	1993-09-01	Derivados piperacinicos y procedimiento para su preparacion.
PT91869A (pt)	1991-03-20	Processo para a preparacao de um novo derivado da 1,4-dihidro-piridina denominado (-)2-<{2-(2-amino-etoxi)-etoxi}-metil>-4-(2,3-dicloro-fenil)-3-etoxicarbomil--5-metoxicarbonil-6-metil-1,4-dihidro-piridina
FI920945L (fi)	1993-09-04	Menetelmä terapeuttisesti käyttökelpoisen 2,3,4,5,6,7-heksahydro-1-(4- 1-/4-(2-metoksifenyyli)piperatsinyyli/ -2-fenyylibutyryyli)-1H-atsepiinin tai sen farmaseuttisesti hyväksyttävän happoadditiosuolan valmis tamiseksi
DE69523346D1 (de)	2001-11-22	Substituierte 6-h-1,3,4-thiadiazin-2-amine, deren verwendung als anaesthetisierende cardiovaskulare und hypometabole mittel, und eine sie enthaltende pharmazeutische zubereitung
ES556219A0 (es)	1987-12-01	Procedimiento para la obtencion de la 3,3-dimetil-n-(4-(4-(2-pirimidinil)-1-piperazinil)butil)glutarimida
RO95572A2 (ro)	1988-09-30	Procedeu pentru prepararea unor derivati de 1,3-oxazolidin-2-ona