DK0481744T3 - Piperazinderivater - Google Patents

Piperazinderivater

Info

Publication number: DK0481744T3
Authority: DK; Denmark
Prior art keywords: piperazine; rsqbstr; lsqbstr; phenylbutyryl; azepin
Prior art date: 1990-10-19

Application number

DK91309513.9T

Other languages

Danish (da)

English (en)

Inventor

Ian Anthony Cliffe

Original Assignee

Wyeth John & Brother Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1990-10-19

Filing date

1991-10-16

Publication date

1996-10-07

1991-10-16 Application filed by Wyeth John & Brother Ltd filed Critical Wyeth John & Brother Ltd

1996-10-07 Application granted granted Critical

1996-10-07 Publication of DK0481744T3 publication Critical patent/DK0481744T3/da

Links

GLUUGHFHXGJENI-UHFFFAOYSA-N Piperazine Chemical compound C1CNCCN1 GLUUGHFHXGJENI-UHFFFAOYSA-N 0.000 title 2
102100022738 5-hydroxytryptamine receptor 1A Human genes 0.000 abstract 1
101710138638 5-hydroxytryptamine receptor 1A Proteins 0.000 abstract 1
239000002253 acid Substances 0.000 abstract 1
239000002249 anxiolytic agent Substances 0.000 abstract 1
230000000949 anxiolytic effect Effects 0.000 abstract 1
229940005530 anxiolytics Drugs 0.000 abstract 1
239000011230 binding agent Substances 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
- C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
- C07D295/182—Radicals derived from carboxylic acids
- C07D295/185—Radicals derived from carboxylic acids from aliphatic carboxylic acids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Veterinary Medicine (AREA)
Life Sciences & Earth Sciences (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Bioinformatics & Cheminformatics (AREA)
Pharmacology & Pharmacy (AREA)
Chemical Kinetics & Catalysis (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Engineering & Computer Science (AREA)
Neurosurgery (AREA)
Neurology (AREA)
Biomedical Technology (AREA)
Heart & Thoracic Surgery (AREA)
Cardiology (AREA)
Anesthesiology (AREA)
Pain & Pain Management (AREA)
Psychiatry (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Pyridine Compounds (AREA)
Other In-Based Heterocyclic Compounds (AREA)
Hydrogenated Pyridines (AREA)
Indole Compounds (AREA)
Polymers With Sulfur, Phosphorus Or Metals In The Main Chain (AREA)

DK91309513.9T 1990-10-19 1991-10-16 Piperazinderivater DK0481744T3 (da)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
GB909022820A GB9022820D0 (en)	1990-10-19	1990-10-19	Piperazine derivatives

Publications (1)

Publication Number	Publication Date
DK0481744T3 true DK0481744T3 (da)	1996-10-07

Family

ID=10684053

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK91309513.9T DK0481744T3 (da)	1990-10-19	1991-10-16	Piperazinderivater

Country Status (15)

Country	Link
EP (1)	EP0481744B1 (pt)
JP (1)	JP3007203B2 (pt)
KR (1)	KR100193928B1 (pt)
AT (1)	ATE143012T1 (pt)
AU (1)	AU642044B2 (pt)
CA (1)	CA2053709C (pt)
DE (1)	DE69122205T2 (pt)
DK (1)	DK0481744T3 (pt)
ES (1)	ES2091879T3 (pt)
GB (2)	GB9022820D0 (pt)
GR (1)	GR3021221T3 (pt)
HU (2)	HU212943B (pt)
IE (1)	IE65379B1 (pt)
NZ (1)	NZ240271A (pt)
PT (1)	PT99251B (pt)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB9125900D0 (en) *	1991-12-05	1992-02-05	Wyeth John & Brother Ltd	Piperazine derivatives
AU675964B2 (en) *	1992-08-05	1997-02-27	John Wyeth & Brother Limited	Amide derivatives
GB9221931D0 (en) *	1992-10-17	1992-12-02	Wyeth John & Brother Ltd	Piperazine derivatives
GB2271930B (en) *	1992-11-03	1996-07-24	Wyeth John & Brother Ltd	Pharmaceutical piperazine derivatives
GB9223153D0 (en) *	1992-11-05	1992-12-16	Wyeth John & Brother Ltd	Piperazine derivatives
GB9303968D0 (en) *	1993-02-26	1993-04-14	Wyeth John & Brother Ltd	5-ht1a ligands
GB9304632D0 (en) *	1993-03-06	1993-04-21	Wyeth John & Brother Ltd	Amide derivatives
US5609849A (en) *	1994-03-11	1997-03-11	The Trustees Of The University Of Pennsylvania	Serotonin (5-HT1A) receptor ligands and imaging agents
GB9419024D0 (en) *	1994-09-21	1994-11-09	Wyeth John & Brother Ltd	Bicyclic carboxamides
GB9525239D0 (en) *	1995-12-09	1996-02-07	American Home Prod	Medical treatment
FR2744448B1 (fr) *	1996-02-02	1998-04-24	Pf Medicament	Nouvelles piperidines derivees d'aryl piperazine, ainsi que leur procede de preparation, les compositions pharmaceutiques et leur utilisation comme medicaments
US5990114A (en) *	1996-02-28	1999-11-23	Recordati, S.A., Chemical And Pharmaceutical Company	Use of 5-HT1A receptor antagonists for the treatment of urinary incontinence
ITMI20021327A1 (it) *	2002-06-14	2003-12-15	Recordati Chem Pharm	Nuove ossialchilpiperazine

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US2776282A (en) *	1954-05-04	1957-01-01	Searle & Co	Cyclic amides of alpha-toluic acids and derivatives thereof
GB8909209D0 (en) *	1989-04-22	1989-06-07	Wyeth John & Brother Ltd	Piperazine derivatives
FI102175B1 (fi) *	1989-04-22	1998-10-30	Wyeth John & Brother Ltd	Menetelmä terapeuttisesti käyttökelpoisten piperatsiinijohdannaisten valmistamiseksi
AU644488B2 (en) *	1990-10-19	1993-12-09	John Wyeth & Brother Limited	Piperazine derivatives

1990
- 1990-10-19 GB GB909022820A patent/GB9022820D0/en active Pending
1991
- 1991-09-02 GB GB9118744A patent/GB2248836B/en not_active Expired - Fee Related
- 1991-10-16 AT AT91309513T patent/ATE143012T1/de not_active IP Right Cessation
- 1991-10-16 DE DE69122205T patent/DE69122205T2/de not_active Expired - Fee Related
- 1991-10-16 DK DK91309513.9T patent/DK0481744T3/da active
- 1991-10-16 EP EP91309513A patent/EP0481744B1/en not_active Expired - Lifetime
- 1991-10-16 ES ES91309513T patent/ES2091879T3/es not_active Expired - Lifetime
- 1991-10-17 AU AU85920/91A patent/AU642044B2/en not_active Ceased
- 1991-10-17 JP JP3269290A patent/JP3007203B2/ja not_active Expired - Fee Related
- 1991-10-17 PT PT99251A patent/PT99251B/pt active IP Right Grant
- 1991-10-17 NZ NZ240271A patent/NZ240271A/xx unknown
- 1991-10-18 KR KR1019910018373A patent/KR100193928B1/ko not_active Expired - Fee Related
- 1991-10-18 CA CA002053709A patent/CA2053709C/en not_active Expired - Fee Related
- 1991-10-18 HU HU913292A patent/HU212943B/hu not_active IP Right Cessation
- 1991-10-18 IE IE366991A patent/IE65379B1/en not_active IP Right Cessation
1995
- 1995-06-27 HU HU95P/P00447P patent/HU211587A9/hu unknown
1996
- 1996-10-02 GR GR960402575T patent/GR3021221T3/el unknown

Also Published As

Publication number	Publication date
EP0481744B1 (en)	1996-09-18
ES2091879T3 (es)	1996-11-16
AU8592091A (en)	1992-04-30
HU913292D0 (en)	1992-01-28
CA2053709A1 (en)	1992-04-20
GB2248836B (en)	1994-05-04
KR920008019A (ko)	1992-05-27
JPH04282371A (ja)	1992-10-07
DE69122205T2 (de)	1997-01-30
EP0481744A1 (en)	1992-04-22
PT99251A (pt)	1992-08-31
KR100193928B1 (ko)	1999-06-15
HU212943B (en)	1996-12-30
ATE143012T1 (de)	1996-10-15
IE913669A1 (en)	1992-04-22
GR3021221T3 (en)	1997-01-31
NZ240271A (en)	1993-03-26
GB9118744D0 (en)	1991-10-16
JP3007203B2 (ja)	2000-02-07
HU211587A9 (en)	1995-12-28
PT99251B (pt)	1999-04-30
DE69122205D1 (de)	1996-10-24
GB2248836A (en)	1992-04-22
CA2053709C (en)	2001-12-11
HUT60264A (en)	1992-08-28
GB9022820D0 (en)	1990-12-05
IE65379B1 (en)	1995-10-18
AU642044B2 (en)	1993-10-07

Publication	Publication Date	Title
DK0481744T3 (da)	1996-10-07	Piperazinderivater
FI960364A7 (fi)	1996-01-26	Uusia 1,4-(difenyylialkyyli)piperatsiinijohdoksia
NO304071B1 (no)	1998-10-19	Heterocyklisk-cykliske amin-derivater
FI933804A0 (fi)	1993-08-31	Monohydrat av 5-(2-(4-(1,2-bensisotiazol-3-yl)-1-piperazinyl)etyl-6-klor-1,3-dihydro-2h-indol-2-onkhydroklorid
DK0590428T3 (da)	2000-05-22	Azaquinoxaliner, fremgangsmåde til deres fremstilling og deres anvendelse
DK0386675T3 (da)	1996-06-24	Xanthinderivater
ATE113282T1 (de)	1994-11-15	Heteroaryl piperazine als antipsychotische mittel.
MX9201760A (es)	1992-10-01	Quinoxalinas, procedimiento para su preparacion y su empleo.
DE69106388D1 (de)	1995-02-09	Antipsychotische 4-(1,2-benzisoazolyl)piperidinderivate.
ATE213943T1 (de)	2002-03-15	Verwendung von piperazin-acetamid-derivaten gegen reperfusionsschaden
NO903640L (no)	1991-02-19	Fremgangsmaate for fremstilling av 2-(rs)-substituerte 2,3-dihydro-5-oksy-4,6,7-trimetylbenzofuraner.
ITMI911520A1 (it)	1992-12-04	Derivati di piperidina, loro preparazione e uso
NZ216750A (en)	1988-11-29	Morpholino derivatives and fungicides
ATE92469T1 (de)	1993-08-15	Neue alpha-aminocarbonsaeure-derivate, ihre herstellung und verwendung.
ATE139523T1 (de)	1996-07-15	Neue verbindungen und deren medizinale verwendung
MX9205186A (es)	1993-03-01	Derivados de 4-[4-[4-(4-hidroxifenil)-1-piperazinil]-fenil]-5-metil-3h-1,2,4-triazo l-3-ona
MY110446A (en)	1998-05-30	Piperazine derivatives
FI870925L (fi)	1987-09-06	4-(2-pyrimidinyl)-1-piperazinyl -heterocykliska karbonylderivater.
DE69523346D1 (de)	2001-11-22	Substituierte 6-h-1,3,4-thiadiazin-2-amine, deren verwendung als anaesthetisierende cardiovaskulare und hypometabole mittel, und eine sie enthaltende pharmazeutische zubereitung
DE50100396D1 (de)	2003-08-28	(+)- und (-)-2-Cyclododecylpropanol und (+)- und (-)-2-Cyclododecylpropionsäure sowie deren Herstellung und Verwendung
ATE151736T1 (de)	1997-05-15	2-arylpropensäuren und ihre verwendung bei der herstellung von s-ketoprofen
DE69307769D1 (de)	1997-03-13	Neue Verwendung von (S) Amino-2-dichloro-3,4-benzyl)-2-propanol-1 Enantiomere Derivate
FI920945L (fi)	1993-09-04	Menetelmä terapeuttisesti käyttökelpoisen 2,3,4,5,6,7-heksahydro-1-(4- 1-/4-(2-metoksifenyyli)piperatsinyyli/ -2-fenyylibutyryyli)-1H-atsepiinin tai sen farmaseuttisesti hyväksyttävän happoadditiosuolan valmis tamiseksi