PT99562A - Metodo para o diagnostico de tumores malignos atraves da deteccao de estromelis ina-3 - Google Patents

Metodo para o diagnostico de tumores malignos atraves da deteccao de estromelis ina-3

Info

Publication number
PT99562A
PT99562A PT99562A PT9956291A PT99562A PT 99562 A PT99562 A PT 99562A PT 99562 A PT99562 A PT 99562A PT 9956291 A PT9956291 A PT 9956291A PT 99562 A PT99562 A PT 99562A
Authority
PT
Portugal
Prior art keywords
diagnosis
detection
estromelis
ina
malignant tumors
Prior art date
Application number
PT99562A
Other languages
English (en)
Other versions
PT99562B (pt
Inventor
Jean-Pierre Bellocq
Pierre Chambon
Original Assignee
Insti Nat De La Sante Et De La
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Insti Nat De La Sante Et De La filed Critical Insti Nat De La Sante Et De La
Publication of PT99562A publication Critical patent/PT99562A/pt
Publication of PT99562B publication Critical patent/PT99562B/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6489—Metalloendopeptidases (3.4.24)
    • C12N9/6491—Matrix metalloproteases [MMP's], e.g. interstitial collagenase (3.4.24.7); Stromelysins (3.4.24.17; 3.2.1.22); Matrilysin (3.4.24.23)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Display Devices Of Pinball Game Machines (AREA)
PT99562A 1990-11-21 1991-11-20 Metodo para o diagnostico de tumores malignos atraves da deteccao de estromelis ina-3 PT99562B (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB9025326A GB2250993B (en) 1990-11-21 1990-11-21 Stromelysin-3 and its application in the diagnosis and treatment of malignant breast cancer

Publications (2)

Publication Number Publication Date
PT99562A true PT99562A (pt) 1992-10-30
PT99562B PT99562B (pt) 1999-04-30

Family

ID=10685753

Family Applications (1)

Application Number Title Priority Date Filing Date
PT99562A PT99562B (pt) 1990-11-21 1991-11-20 Metodo para o diagnostico de tumores malignos atraves da deteccao de estromelis ina-3

Country Status (16)

Country Link
US (1) US5236844A (pt)
EP (1) EP0513316B1 (pt)
JP (1) JP3516448B2 (pt)
AT (1) ATE152179T1 (pt)
CA (1) CA2073860A1 (pt)
DE (1) DE69125824T2 (pt)
DK (1) DK0513316T3 (pt)
ES (1) ES2101079T3 (pt)
GB (1) GB2250993B (pt)
GR (1) GR3023560T3 (pt)
HU (1) HU215165B (pt)
IE (1) IE914056A1 (pt)
NZ (2) NZ240688A (pt)
PT (1) PT99562B (pt)
WO (1) WO1992009701A1 (pt)
ZA (1) ZA919219B (pt)

Families Citing this family (43)

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Publication number Priority date Publication date Assignee Title
EP0670902A1 (en) * 1992-11-25 1995-09-13 University Of Pittsburgh Of The Commonwealth System Of Higher Education cDNA CLONE FOR HUMAN INDUCIBLE NITRIC OXYDE SYNTHASE AND PROCESS FOR PREPARING SAME
AU7401394A (en) * 1993-07-20 1995-02-20 University Of Massachusetts Medical Center In vivo nucleic acid hybridization method
EP0685557B1 (en) * 1993-11-30 1998-08-12 Fuji Yakuhin Kogyo Kabushiki Kaisha Novel metalloprotease and dna coding for the same
JPH07303482A (ja) 1993-11-30 1995-11-21 Fuji Yakuhin Kogyo Kk 新規なメタロプロテアーゼおよびそれをコードするｄｎａ
US6825024B1 (en) 1993-11-30 2004-11-30 Fuji Yakuhin Kogyo Kabushiki Kaisha Metalloproteinase and encoding DNA therefor
US5709999A (en) * 1994-08-12 1998-01-20 Myriad Genetics Inc. Linked breast and ovarian cancer susceptibility gene
US5710001A (en) * 1994-08-12 1998-01-20 Myriad Genetics, Inc. 17q-linked breast and ovarian cancer susceptibility gene
US5753441A (en) * 1994-08-12 1998-05-19 Myriad Genetics, Inc. 170-linked breast and ovarian cancer susceptibility gene
US5747282A (en) * 1994-08-12 1998-05-05 Myraid Genetics, Inc. 17Q-linked breast and ovarian cancer susceptibility gene
US5763415A (en) * 1995-08-03 1998-06-09 John Hopkins University School Of Medicine Destruction of the epithelium of an exocrine gland in the prophylactic and therapeutic treatment of cancer
EP0789758A2 (en) * 1995-09-05 1997-08-20 Celltech Therapeutics Limited Dna sequences coding for a human metalloproteinase and variants thereof
US5905027A (en) * 1995-12-27 1999-05-18 Uab Research Foundation Method of diagnosing and treating gliomas
CA2252509A1 (en) * 1996-04-25 1997-10-30 Takeda Chemical Industries, Ltd. Matrix metalloprotease
US20030165971A1 (en) * 1996-10-31 2003-09-04 Billing-Medel Patricia A. Reagents and methods useful for detecting diseases of the breast
US20050202499A1 (en) 1996-10-31 2005-09-15 Billing-Medel Patricia A. Reagents and methods useful for detecting diseases of the breast
US20050153373A1 (en) * 1996-10-31 2005-07-14 Billing-Medel Patricia A. Reagents and methods useful for detecting diseases of the breast
JP4614472B2 (ja) * 1996-10-31 2011-01-19 アボット・ラボラトリーズ 乳房の疾患の検出に有用な試薬および方法
WO1998024935A1 (en) * 1996-12-06 1998-06-11 Urocor, Inc. Diagnosis of disease state using mrna profiles
WO1998040475A1 (en) * 1997-03-11 1998-09-17 Abbott Laboratories Human matrix metalloprotease gene, proteins encoded therefrom and methods of using same
EP0969868A2 (en) 1997-03-18 2000-01-12 Ortho-Mcneil Pharmaceutical, Inc. Methods and kits for treating and diagnosing leiomyomas
US6190857B1 (en) 1997-03-24 2001-02-20 Urocor, Inc. Diagnosis of disease state using MRNA profiles in peripheral leukocytes
US7332270B1 (en) 1997-03-24 2008-02-19 Urocor, Inc. Diagnosis of disease state using mRNA profiles in peripheral leukocytes
WO1999002714A1 (en) * 1997-07-07 1999-01-21 Abbott Laboratories Reagents and methods useful for detecting diseases of the breast
US20040072210A1 (en) * 1997-07-07 2004-04-15 Billing-Medel Patricia A. Reagents and methods useful for detecting diseases of the breast
CA2309756A1 (en) * 1997-11-17 1999-05-27 Abbott Laboratories Reagents and methods useful for detecting diseases of the breast
US5972615A (en) 1998-01-21 1999-10-26 Urocor, Inc. Biomarkers and targets for diagnosis, prognosis and management of prostate disease
US6600057B2 (en) 2000-12-29 2003-07-29 Kimberly-Clark Worldwide, Inc. Matrix metalloproteinase inhibitors
US7041787B2 (en) * 2000-12-29 2006-05-09 Kimberly-Clark Worldwide, Inc. Design and use of advanced zinc chelating peptides to regulate matrix metalloproteinases
WO2003006641A2 (en) * 2001-07-09 2003-01-23 Københavns Universitet Epsti1, a gene induced by epithelial-stromal interaction in human breast cancer
US20030119073A1 (en) * 2001-12-21 2003-06-26 Stephen Quirk Sensors and methods of detection for proteinase enzymes
DE10217254A1 (de) * 2002-04-15 2003-10-23 Proteosys Ag Verwendung von Substanzen zur Behandlung von Tumoren
US20060088899A1 (en) * 2002-05-31 2006-04-27 Alvarez Vernon L Combination chemotherapy with chlorotoxin
US20050193432A1 (en) * 2003-11-18 2005-09-01 Whitehead Institute For Biomedical Research Xenograft model of functional normal and malignant human breast tissues in rodents and methods thereof
US7569662B2 (en) * 2004-01-27 2009-08-04 Compugen Ltd Nucleotide and amino acid sequences, and assays and methods of use thereof for diagnosis of lung cancer
US7667001B1 (en) * 2004-01-27 2010-02-23 Compugen Ltd. Nucleotide and amino acid sequences, and assays and methods of use thereof for diagnosis of lung cancer
WO2006130472A2 (en) * 2005-05-27 2006-12-07 The Regents Of The University Of California Identification of rac1b as a marker and mediator of matrix metalloproteinase-induced malignancy
CA2724384A1 (en) 2008-05-15 2009-11-19 Transmolecular, Inc. Treatment of metastatic tumors
CN102844044B (zh) 2010-02-04 2016-10-26 摩尔弗泰克有限公司 氯毒素多肽和结合物及其应用
EP3165533B1 (en) 2010-05-11 2020-04-08 Fred Hutchinson Cancer Research Center Chlorotoxin variants, conjugates and methods for their use
KR101313184B1 (ko) * 2010-06-24 2013-09-30 한국표준과학연구원 질병 지표 검출 키트 및 질병 지표 검출 방법
CA2913029A1 (en) 2012-12-10 2014-06-19 Fred Hutchinson Cancer Research Center Lipocalin fusion partners
US11559580B1 (en) 2013-09-17 2023-01-24 Blaze Bioscience, Inc. Tissue-homing peptide conjugates and methods of use thereof
US12048732B2 (en) 2016-04-15 2024-07-30 Blaze Bioscience, Inc. Methods of treating breast cancer

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS63503514A (ja) * 1986-06-17 1988-12-22 セルテク・リミテツド タンパク質の製法

Also Published As

Publication number Publication date
EP0513316A1 (fr) 1992-11-19
GB2250993A (en) 1992-06-24
WO1992009701A1 (fr) 1992-06-11
GR3023560T3 (en) 1997-08-29
GB2250993B (en) 1995-02-15
DK0513316T3 (da) 1997-05-20
PT99562B (pt) 1999-04-30
CA2073860A1 (en) 1992-05-22
ZA919219B (en) 1992-10-28
JPH05505530A (ja) 1993-08-19
IE914056A1 (en) 1992-06-03
DE69125824T2 (de) 1997-08-07
NZ240688A (en) 1994-09-27
AU9089691A (en) 1992-06-25
HU215165B (hu) 1998-10-28
HU9202368D0 (en) 1992-10-28
EP0513316B1 (fr) 1997-04-23
US5236844A (en) 1993-08-17
JP3516448B2 (ja) 2004-04-05
NZ260705A (en) 1997-05-26
GB9025326D0 (en) 1991-01-02
ATE152179T1 (de) 1997-05-15
ES2101079T3 (es) 1997-07-01
HUT65373A (en) 1994-05-02
AU646914B2 (en) 1994-03-10
DE69125824D1 (de) 1997-05-28

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Legal Events

Date Code Title Description
BB1A Laying open of patent application

Effective date: 19920602

FG3A Patent granted, date of granting

Effective date: 19990129

MM3A Annulment or lapse

Effective date: 20050729