SA99200718B1 - عامل فعال activ agent في صورة مسحوق جاف dry powder للاعطاء في الرئة lung - Google Patents

عامل فعال activ agent في صورة مسحوق جاف dry powder للاعطاء في الرئة lung Download PDF

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Publication number
SA99200718B1
SA99200718B1 SA99200718A SA99200718A SA99200718B1 SA 99200718 B1 SA99200718 B1 SA 99200718B1 SA 99200718 A SA99200718 A SA 99200718A SA 99200718 A SA99200718 A SA 99200718A SA 99200718 B1 SA99200718 B1 SA 99200718B1
Authority
SA
Saudi Arabia
Prior art keywords
particles
active agent
lung
cyclodextrin
hygroscopic
Prior art date
Application number
SA99200718A
Other languages
Arabic (ar)
English (en)
Inventor
اندرو كلارك
مي- شانج كو
سيسلي لالور
Original Assignee
انهالي ثيرابيوتيك سيستمز ، انك
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by انهالي ثيرابيوتيك سيستمز ، انك filed Critical انهالي ثيرابيوتيك سيستمز ، انك
Publication of SA99200718B1 publication Critical patent/SA99200718B1/ar

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/007Pulmonary tract; Aromatherapy
    • A61K9/0073Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0075Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a dry powder inhaler [DPI], e.g. comprising micronized drug mixed with lactose carrier particles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/08Bronchodilators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pulmonology (AREA)
  • Epidemiology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Otolaryngology (AREA)
  • Inorganic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
SA99200718A 1998-09-14 1999-10-31 عامل فعال activ agent في صورة مسحوق جاف dry powder للاعطاء في الرئة lung SA99200718B1 (ar)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US10016398P 1998-09-14 1998-09-14

Publications (1)

Publication Number Publication Date
SA99200718B1 true SA99200718B1 (ar) 2006-11-04

Family

ID=22278404

Family Applications (1)

Application Number Title Priority Date Filing Date
SA99200718A SA99200718B1 (ar) 1998-09-14 1999-10-31 عامل فعال activ agent في صورة مسحوق جاف dry powder للاعطاء في الرئة lung

Country Status (44)

Country Link
EP (1) EP1117442A1 (fr)
JP (1) JP2002524535A (fr)
KR (1) KR20010075063A (fr)
CN (1) CN1317977A (fr)
AP (1) AP1374A (fr)
AR (1) AR022090A1 (fr)
AU (1) AU753014B2 (fr)
BG (1) BG105430A (fr)
BR (1) BR9913722A (fr)
CA (1) CA2343920A1 (fr)
CO (1) CO5130023A1 (fr)
CZ (1) CZ2001829A3 (fr)
DZ (1) DZ2892A1 (fr)
EA (1) EA003476B1 (fr)
EE (1) EE200100151A (fr)
GE (1) GEP20043257B (fr)
GT (1) GT199900156A (fr)
HK (1) HK1042231A1 (fr)
HN (1) HN1999000159A (fr)
HR (1) HRP20010189A2 (fr)
HU (1) HUP0103837A3 (fr)
ID (1) ID28845A (fr)
IL (2) IL141562A0 (fr)
IS (1) IS5878A (fr)
LT (1) LT4897B (fr)
LV (1) LV12658B (fr)
MA (1) MA25590A1 (fr)
MY (1) MY129282A (fr)
NO (1) NO20011251L (fr)
NZ (1) NZ510168A (fr)
OA (1) OA11781A (fr)
PA (1) PA8481901A1 (fr)
PE (1) PE20001061A1 (fr)
PL (1) PL195574B1 (fr)
SA (1) SA99200718B1 (fr)
SK (1) SK3442001A3 (fr)
TN (1) TNSN99173A1 (fr)
TR (1) TR200101182T2 (fr)
TW (1) TWI226248B (fr)
UA (1) UA76085C2 (fr)
UY (1) UY25711A1 (fr)
WO (1) WO2000015262A1 (fr)
YU (1) YU24201A (fr)
ZA (1) ZA200101995B (fr)

Families Citing this family (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6956021B1 (en) 1998-08-25 2005-10-18 Advanced Inhalation Research, Inc. Stable spray-dried protein formulations
HK1049621A1 (zh) 1999-06-09 2003-05-23 罗伯特‧E‧希弗斯 超临界流体辅助的喷雾和鼓泡乾燥
US6475468B2 (en) * 2001-02-15 2002-11-05 Aeropharm Technology Incorporated Modulated release particles for aerosol delivery
JP2005503425A (ja) * 2001-05-24 2005-02-03 アレックザ モレキュラー デリヴァリー コーポレイション 所定の吸入ルートによる薬剤エステルの送出
EG24184A (en) * 2001-06-15 2008-10-08 Otsuka Pharma Co Ltd Dry powder inhalation system for transpulmonary
AU2002352836B2 (en) 2001-11-20 2005-09-29 Alkermes, Inc. Improved particulate compositions for pulmonary delivery
CA2477245A1 (fr) 2002-02-25 2003-09-04 Diffusion Pharmaceuticals Llc Sels carotenoides trans bipolaires et leurs utilisations
US7759506B2 (en) 2002-02-25 2010-07-20 Diffusion Pharmaceuticals Llc Bipolar trans carotenoid salts and their uses
WO2004004798A2 (fr) * 2002-07-03 2004-01-15 The Brigham And Women's Hospital, Inc. Introduction par les voies aeriennes centrales pour l'administration systemique d'agents therapeutiques
EP1575563B1 (fr) * 2002-12-19 2007-02-14 Pharmacia Corporation Formulation a caractere non-hygroscopique comprenant un principe actif hydroscopique
DE10338403A1 (de) * 2003-08-18 2005-03-17 Boehringer Ingelheim Pharma Gmbh & Co. Kg Pulverformulierung, enthaltend den CGRP-Antagonisten 1-[N2-[3,5-Dibrom-N-[[4-(3,4-dihydro-2(1H)-oxochinazolin-3-yl]-1-piperidinyl]carbonyl]-D-tyrosyl]-L-lysyl]-4-(4-pyrindinyl)-piperazin, Verfahren zu dessen Herstellung sowie dessen Verwendung als Inhalativum
GB0327723D0 (en) * 2003-09-15 2003-12-31 Vectura Ltd Pharmaceutical compositions
US20070020299A1 (en) 2003-12-31 2007-01-25 Pipkin James D Inhalant formulation containing sulfoalkyl ether cyclodextrin and corticosteroid
CN101098678A (zh) 2004-04-23 2008-01-02 锡德克斯公司 含有磺基烷基醚环糊精的dpi制剂
EP2540696B1 (fr) 2005-02-24 2020-01-01 Diffusion Pharmaceuticals LLC Transcaroténoïdes, formulation les comprenant et leurs utilisations
BRPI0608844A2 (pt) * 2005-03-09 2010-02-02 Ono Pharmaceutical Co partìcula e preparação que contém a partìcula
US7629331B2 (en) 2005-10-26 2009-12-08 Cydex Pharmaceuticals, Inc. Sulfoalkyl ether cyclodextrin compositions and methods of preparation thereof
PT2583668E (pt) 2005-10-26 2015-01-05 Cydex Pharmaceuticals Inc Composições de éter sulfoalquílico de ciclodextrina e métodos para a sua preparação
WO2008021451A2 (fr) * 2006-08-14 2008-02-21 Aktiv-Dry Llc Inhalateur à poudre sèche actionné par l'homme et compositions à inhaler sous forme de poudre sèche
JP5315056B2 (ja) * 2006-10-25 2013-10-16 大日本住友製薬株式会社 固結抑制粒状製剤
EP1925295A1 (fr) * 2006-11-22 2008-05-28 Boehringer Ingelheim Pharma GmbH & Co. KG Formule de poudre stable contenant un nouveau anticholinergique
CN101687757A (zh) 2007-04-13 2010-03-31 扩散药品有限公司 双极性反式类胡萝卜素作为预治疗及其在周围血管疾病的治疗中的应用
US12370352B2 (en) 2007-06-28 2025-07-29 Cydex Pharmaceuticals, Inc. Nasal and ophthalmic delivery of aqueous corticosteroid solutions
KR20100083820A (ko) 2007-10-31 2010-07-22 디퓨젼 파마슈티컬즈 엘엘씨 저분자 확산을 촉진시키는 신규한 치료요법
ES2661215T3 (es) 2009-05-20 2018-03-28 Aeras Composiciones víricas; inmunógenas; secadas por pulverización; estables
EP2445339B1 (fr) 2009-06-22 2019-08-07 Diffusion Pharmaceuticals LLC Composé améliorant la diffusion et son utilisation avec un thrombolytique
AU2011262361A1 (en) 2010-06-02 2013-01-10 Diffusion Pharmaceuticals Llc Oral formulations of bipolar trans carotenoids
KR102240042B1 (ko) * 2012-05-03 2021-04-14 얀센 사이언시즈 아일랜드 언리미티드 컴퍼니 상기도 감염 치료용 폴리이노신산-폴리사이티딜산(폴리 (i:c)) 제형
BR112015010601B1 (pt) * 2012-11-09 2022-07-19 Civitas Therapeutics, Inc. Composição farmacêutica e uso da composição
US20180043585A9 (en) * 2013-09-20 2018-02-15 Virginia Commonwealth University Delivery of particles using hygroscopic excipients
MX392636B (es) 2014-10-31 2025-03-24 Glaxosmithkline Ip Dev Ltd Formulacion en polvo.
CA3018550A1 (fr) 2016-03-24 2017-09-28 Diffusion Pharmaceuticals Llc Utilisation de carotenoides trans bipolaires avec une chimiotherapie et une radiotherapie en vue du traitement d'un cancer
US20220378727A1 (en) * 2021-05-14 2022-12-01 The University Of Hong Kong Dry powder formulations of tamibarotene for pulmonary and intranasal delivery

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3155573A (en) * 1958-05-06 1964-11-03 Benger Lab Ltd Inhalant composition and method of making same
CA2115065C (fr) * 1992-06-12 2000-10-03 Kiyoyuki Sakon Poudre particulaire ultrafine pour inhalation et methode de production
US6524557B1 (en) * 1994-12-22 2003-02-25 Astrazeneca Ab Aerosol formulations of peptides and proteins
US5874064A (en) 1996-05-24 1999-02-23 Massachusetts Institute Of Technology Aerodynamically light particles for pulmonary drug delivery
CA2277801C (fr) * 1997-01-16 2002-10-15 Massachusetts Institute Of Technology Preparation de particules pour inhalation
US6086376A (en) * 1998-01-30 2000-07-11 Rtp Pharma Inc. Dry aerosol suspension of phospholipid-stabilized drug microparticles in a hydrofluoroalkane propellant

Also Published As

Publication number Publication date
KR20010075063A (ko) 2001-08-09
TR200101182T2 (tr) 2001-09-21
NZ510168A (en) 2003-09-26
CO5130023A1 (es) 2002-02-27
ID28845A (id) 2001-07-05
MY129282A (en) 2007-03-30
OA11781A (en) 2005-07-26
HUP0103837A3 (en) 2002-11-28
NO20011251D0 (no) 2001-03-13
BG105430A (en) 2001-12-29
YU24201A (sh) 2003-08-29
AR022090A1 (es) 2002-09-04
AU753014B2 (en) 2002-10-03
LT2001021A (en) 2001-11-26
EA003476B1 (ru) 2003-06-26
EP1117442A1 (fr) 2001-07-25
PL195574B1 (pl) 2007-10-31
IL141562A (en) 2007-07-24
AP2001002093A0 (en) 2001-03-31
MA25590A1 (fr) 2002-12-31
TWI226248B (en) 2005-01-11
SK3442001A3 (en) 2001-11-06
LT4897B (lt) 2002-02-25
CZ2001829A3 (cs) 2001-09-12
PL346768A1 (en) 2002-02-25
EE200100151A (et) 2002-06-17
LV12658B (lv) 2001-09-20
UY25711A1 (es) 1999-11-17
JP2002524535A (ja) 2002-08-06
EA200100300A1 (ru) 2001-10-22
WO2000015262A1 (fr) 2000-03-23
NO20011251L (no) 2001-04-17
IL141562A0 (en) 2002-03-10
TNSN99173A1 (fr) 2005-11-10
GEP20043257B (en) 2004-06-25
GT199900156A (es) 2001-03-07
AP1374A (en) 2005-02-28
ZA200101995B (en) 2002-03-11
HRP20010189A2 (en) 2005-04-30
LV12658A (lv) 2001-05-20
UA76085C2 (en) 2006-07-17
IS5878A (is) 2001-03-05
BR9913722A (pt) 2001-05-29
PE20001061A1 (es) 2000-10-08
CN1317977A (zh) 2001-10-17
HK1042231A1 (zh) 2002-08-09
HUP0103837A2 (hu) 2002-05-29
DZ2892A1 (fr) 2003-12-15
HN1999000159A (es) 1999-11-11
PA8481901A1 (es) 2002-04-25
AU6039799A (en) 2000-04-03
CA2343920A1 (fr) 2000-03-23

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