SE0101329D0 - Pharmaceutical formulation - Google Patents

Pharmaceutical formulation

Info

Publication number
SE0101329D0
SE0101329D0 SE0101329A SE0101329A SE0101329D0 SE 0101329 D0 SE0101329 D0 SE 0101329D0 SE 0101329 A SE0101329 A SE 0101329A SE 0101329 A SE0101329 A SE 0101329A SE 0101329 D0 SE0101329 D0 SE 0101329D0
Authority
SE
Sweden
Prior art keywords
oxa
butyl
compositions
diazabicyclo
tert
Prior art date
Application number
SE0101329A
Other languages
English (en)
Swedish (sv)
Inventor
Anna Lundgren
Christina Aaberg
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Priority to SE0101329A priority Critical patent/SE0101329D0/xx
Publication of SE0101329D0 publication Critical patent/SE0101329D0/xx
Priority to TW091106495A priority patent/TWI257391B/zh
Priority to ARP020101187A priority patent/AR035806A1/es
Priority to JP2002581444A priority patent/JP2005500262A/ja
Priority to HU0303486A priority patent/HUP0303486A3/hu
Priority to CA002443473A priority patent/CA2443473A1/en
Priority to DE60213084T priority patent/DE60213084T2/de
Priority to NZ528561A priority patent/NZ528561A/en
Priority to MXPA03009209A priority patent/MXPA03009209A/es
Priority to PL02366629A priority patent/PL366629A1/xx
Priority to EP02723011A priority patent/EP1389212B1/en
Priority to EEP200300495A priority patent/EE200300495A/xx
Priority to KR10-2003-7013299A priority patent/KR20030088498A/ko
Priority to PCT/SE2002/000726 priority patent/WO2002083689A1/en
Priority to BR0208828-2A priority patent/BR0208828A/pt
Priority to US10/474,584 priority patent/US20050037067A1/en
Priority to IL15803302A priority patent/IL158033A0/xx
Priority to CNA028116364A priority patent/CN1514839A/zh
Priority to AT02723011T priority patent/ATE332902T1/de
Priority to SK1256-2003A priority patent/SK12562003A3/sk
Priority to CZ20032774A priority patent/CZ20032774A3/cs
Priority to RU2003129230/15A priority patent/RU2003129230A/ru
Priority to ZA200307756A priority patent/ZA200307756B/en
Priority to BG108234A priority patent/BG108234A/bg
Priority to NO20034529A priority patent/NO20034529L/no
Priority to IS6989A priority patent/IS6989A/is

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D498/08—Bridged systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/5375—1,4-Oxazines, e.g. morpholine
    • A61K31/5386—1,4-Oxazines, e.g. morpholine spiro-condensed or forming part of bridged ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12—Carboxylic acids; Salts or anhydrides thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/38—Cellulose; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/40—Cyclodextrins; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2009—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Inorganic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
SE0101329A 2001-04-12 2001-04-12 Pharmaceutical formulation SE0101329D0 (sv)

Priority Applications (26)

Application Number Priority Date Filing Date Title
SE0101329A SE0101329D0 (sv) 2001-04-12 2001-04-12 Pharmaceutical formulation
TW091106495A TWI257391B (en) 2001-04-12 2002-04-01 New pharmaceutical formulation suitable for antiarrhythmic compounds
ARP020101187A AR035806A1 (es) 2001-04-12 2002-04-02 Formulacion farmaceutica de liberacion inmediata apropiada para compuestos antiarritmicos, procedimiento para su preparacion, composicion farmaceutica solida, composicion liofilizada, uso de la formulacion o la composicion para la manufactura de un medicamento para ser usado en la profilaxis o trata
RU2003129230/15A RU2003129230A (ru) 2001-04-12 2002-04-12 3,7-диазабицикло[3.3.1]-препараты как антиаритмические соединения
KR10-2003-7013299A KR20030088498A (ko) 2001-04-12 2002-04-12 항부정맥 화합물로서의 3,7-디아자비시클로[3.3.1] 제제
BR0208828-2A BR0208828A (pt) 2001-04-12 2002-04-12 Formulação farmacêutica de liberação imediata, processo para a preparação de uma formulação, composição farmacêutica sólida, processo para a formação de uma composição, uso de uma formulação, e, método de profilaxia ou tratamento de uma arritmia
CA002443473A CA2443473A1 (en) 2001-04-12 2002-04-12 3,7-diazabicyclo [3.3.1] formulations as anti-arrythmic compounds
DE60213084T DE60213084T2 (de) 2001-04-12 2002-04-12 3,7-DIAZABICYCLOc3.3.1Ü-FORMULIERUNGEN ALS ANTIARRHYTHMIKA
NZ528561A NZ528561A (en) 2001-04-12 2002-04-12 3,7-diazabicyclo [3.3.1] formulations as anti-arrythmic compounds
MXPA03009209A MXPA03009209A (es) 2001-04-12 2002-04-12 Formulaciones de 3,7-diazabiciclo-[3.3.1] como compuestos anti-arritmicos.
PL02366629A PL366629A1 (en) 2001-04-12 2002-04-12 3,7-diazabicyclo [3.3.1] formulations as anti-arrythmic compounds
EP02723011A EP1389212B1 (en) 2001-04-12 2002-04-12 3,7-diazabicyclo 3.3.1| formulations as anti-arrythmic compounds
EEP200300495A EE200300495A (et) 2001-04-12 2002-04-12 3,7-diasabitsüklo[3.3.1]preparaadid, nende valmistamise meetod ja nimetatud preparaatide kasutaminesüdame arütmiate profülaktikas või ravis
JP2002581444A JP2005500262A (ja) 2001-04-12 2002-04-12 抗不整脈化合物としての3,7−ジアザビシクロ[3.3.1]製剤
PCT/SE2002/000726 WO2002083689A1 (en) 2001-04-12 2002-04-12 3,7-diazabicyclo [3.3.1] formulations as anti-arrythmic compounds
HU0303486A HUP0303486A3 (en) 2001-04-12 2002-04-12 Compositions containing 3,7-diazabicyclo [3,3,1] compounds as anti-arrythmic compounds agents
US10/474,584 US20050037067A1 (en) 2001-04-12 2002-04-12 3,7-Diazabicyclo [3.3.1]formulations as anti-arrhythmic compounds
IL15803302A IL158033A0 (en) 2001-04-12 2002-04-12 3, 7-diazabicyclo [3.3.1] formulations as anti-arrhythmic compounds
CNA028116364A CN1514839A (zh) 2001-04-12 2002-04-12 作为抗心律失常化合物的3,7-二氮杂双环[3.3.1]制剂
AT02723011T ATE332902T1 (de) 2001-04-12 2002-04-12 3,7-diazabicycloc3.3.1)-formulierungen als antiarrhythmika
SK1256-2003A SK12562003A3 (sk) 2001-04-12 2002-04-12 Formulácie obsahujúce deriváty 3,7-diazabicyklo-[3.3.1]-zlúčenín, spôsob ich prípravy a ich použitie ako antiarytmických činidiel
CZ20032774A CZ20032774A3 (cs) 2001-04-12 2002-04-12 Kompozice obsahující deriváty 3,7-diazabicyklo[3.3.1]sloučenin, způsob jejich přípravy a jejich použití jako antiarytmických činidel
ZA200307756A ZA200307756B (en) 2001-04-12 2003-10-03 3,7-Diazabicyclo[3.3.1]formulations as anti-arrythmic compounds.
BG108234A BG108234A (bg) 2001-04-12 2003-10-06 3,7-диазабицикло[ 3.3.1] състави включващи антиаритмични съединения
NO20034529A NO20034529L (no) 2001-04-12 2003-10-09 3,7-diazabicyklo(3,3,1) - formuleringer som anti-arytmi- forbindelser
IS6989A IS6989A (is) 2001-04-12 2003-10-10 3,7-díasabísýkló [3.3.1] blöndur sem efnasambönd gegn sláttarglöpum

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE0101329A SE0101329D0 (sv) 2001-04-12 2001-04-12 Pharmaceutical formulation

Publications (1)

Publication Number Publication Date
SE0101329D0 true SE0101329D0 (sv) 2001-04-12

Family

ID=20283785

Family Applications (1)

Application Number Title Priority Date Filing Date
SE0101329A SE0101329D0 (sv) 2001-04-12 2001-04-12 Pharmaceutical formulation

Country Status (26)

Country Link
US (1) US20050037067A1 (no)
EP (1) EP1389212B1 (no)
JP (1) JP2005500262A (no)
KR (1) KR20030088498A (no)
CN (1) CN1514839A (no)
AR (1) AR035806A1 (no)
AT (1) ATE332902T1 (no)
BG (1) BG108234A (no)
BR (1) BR0208828A (no)
CA (1) CA2443473A1 (no)
CZ (1) CZ20032774A3 (no)
DE (1) DE60213084T2 (no)
EE (1) EE200300495A (no)
HU (1) HUP0303486A3 (no)
IL (1) IL158033A0 (no)
IS (1) IS6989A (no)
MX (1) MXPA03009209A (no)
NO (1) NO20034529L (no)
NZ (1) NZ528561A (no)
PL (1) PL366629A1 (no)
RU (1) RU2003129230A (no)
SE (1) SE0101329D0 (no)
SK (1) SK12562003A3 (no)
TW (1) TWI257391B (no)
WO (1) WO2002083689A1 (no)
ZA (1) ZA200307756B (no)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI259836B (en) * 2001-04-12 2006-08-11 Astrazeneca Ab Modified release formulation suitable for antiarrhythmic compounds
US8158152B2 (en) * 2005-11-18 2012-04-17 Scidose Llc Lyophilization process and products obtained thereby
GB0523810D0 (en) * 2005-11-23 2006-01-04 Astrazeneca Ab Pharmaceutical compositions
JP5235676B2 (ja) * 2005-12-20 2013-07-10 レツク・フアーマシユーテイカルズ・デー・デー (e)−7−〔4−(4−フルオロフェニル)−6−イソプロピル−2−〔メチル(メチルスルホニル)アミノ〕ピリミジン−5−イル〕−(3r,5s)−3,5−ジヒドロキシヘプタ−6−エン酸を含む医薬組成物
US20080085303A1 (en) * 2006-10-10 2008-04-10 Penwest Pharmaceuticals Co. Robust sustained release formulations of oxymorphone and methods of use thereof
CA2644179C (en) * 2007-11-21 2018-09-25 Pharmascience Inc. Novel pharmaceutical composition comprising a disintegration matrix
DE102008047910A1 (de) 2008-09-19 2010-03-25 Molkerei Meggle Wasserburg Gmbh & Co. Kg Tablettierhilfsstoff auf Laktose- und Cellulosebasis
US9408835B2 (en) * 2013-03-29 2016-08-09 Astellas Pharma Inc. Pharmaceutical composition for oral administration

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3732094A1 (de) * 1987-09-24 1989-04-06 Basf Ag Bispidinderivate als klasse iii-antiarrhythmika
US5110933A (en) * 1989-11-13 1992-05-05 Board Of Regents Of Oklahoma State University Salts of 3-azabicyclo[3.3.1]nonanes as antiarrhythmic agents, and precursors thereof
DE4402933A1 (de) * 1994-02-01 1995-08-03 Kali Chemie Pharma Gmbh Neue 3-Benzoyl-3,7-diazabicyclo[3,3,1] nonan-Verbindungen enthaltende Arzneimittel
SE9704709D0 (sv) * 1997-12-17 1997-12-17 Astra Ab Pharmaceutically active compounds
HUP0202214A3 (en) * 1999-04-09 2002-12-28 Astrazeneca Ab Adamantane derivatives, preparation and use thereof
SE9903759D0 (sv) * 1999-10-18 1999-10-18 Astra Ab Pharmaceutically active compounds
US6500457B1 (en) * 2000-08-14 2002-12-31 Peirce Management, Llc Oral pharmaceutical dosage forms for pulsatile delivery of an antiarrhythmic agent

Also Published As

Publication number Publication date
ZA200307756B (en) 2005-01-03
BR0208828A (pt) 2004-03-09
MXPA03009209A (es) 2004-01-29
US20050037067A1 (en) 2005-02-17
WO2002083689A1 (en) 2002-10-24
DE60213084D1 (de) 2006-08-24
IS6989A (is) 2003-10-10
CN1514839A (zh) 2004-07-21
PL366629A1 (en) 2005-02-07
SK12562003A3 (sk) 2004-03-02
CA2443473A1 (en) 2002-10-24
RU2003129230A (ru) 2005-04-10
DE60213084T2 (de) 2007-01-11
KR20030088498A (ko) 2003-11-19
NZ528561A (en) 2005-03-24
HUP0303486A2 (hu) 2004-01-28
NO20034529L (no) 2003-12-08
TWI257391B (en) 2006-07-01
EE200300495A (et) 2003-12-15
AR035806A1 (es) 2004-07-14
EP1389212B1 (en) 2006-07-12
ATE332902T1 (de) 2006-08-15
BG108234A (bg) 2005-04-30
EP1389212A1 (en) 2004-02-18
CZ20032774A3 (cs) 2004-01-14
JP2005500262A (ja) 2005-01-06
IL158033A0 (en) 2004-03-28
HUP0303486A3 (en) 2005-04-28
NO20034529D0 (no) 2003-10-09

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