SE0402100D0 - Molded micro-needles - Google Patents

Molded micro-needles

Info

Publication number
SE0402100D0
SE0402100D0 SE0402100A SE0402100A SE0402100D0 SE 0402100 D0 SE0402100 D0 SE 0402100D0 SE 0402100 A SE0402100 A SE 0402100A SE 0402100 A SE0402100 A SE 0402100A SE 0402100 D0 SE0402100 D0 SE 0402100D0
Authority
SE
Sweden
Prior art keywords
micro
projections
mold
molds
positive
Prior art date
Application number
SE0402100A
Other languages
English (en)
Swedish (sv)
Inventor
Patrick Griss
Goeran Stemme
Original Assignee
Bonsens Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bonsens Ab filed Critical Bonsens Ab
Priority to SE0402100A priority Critical patent/SE0402100D0/xx
Publication of SE0402100D0 publication Critical patent/SE0402100D0/xx
Priority to AT05776430T priority patent/ATE444096T1/de
Priority to EP05776430A priority patent/EP1796778B1/de
Priority to US11/661,113 priority patent/US7981346B2/en
Priority to DE602005016951T priority patent/DE602005016951D1/de
Priority to JP2007529775A priority patent/JP2008511382A/ja
Priority to PCT/SE2005/001260 priority patent/WO2006025786A1/en

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C45/00—Injection moulding, i.e. forcing the required volume of moulding material through a nozzle into a closed mould; Apparatus therefor
    • B29C45/17—Component parts, details or accessories; Auxiliary operations
    • B29C45/26—Moulds
    • B29C45/2628—Moulds with mould parts forming holes in or through the moulded article, e.g. for bearing cages
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0021—Intradermal administration, e.g. through microneedle arrays or needleless injectors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B81—MICROSTRUCTURAL TECHNOLOGY
    • B81C—PROCESSES OR APPARATUS SPECIALLY ADAPTED FOR THE MANUFACTURE OR TREATMENT OF MICROSTRUCTURAL DEVICES OR SYSTEMS
    • B81C99/00—Subject matter not provided for in other groups of this subclass
    • B81C99/0075—Manufacture of substrate-free structures
    • B81C99/0085—Manufacture of substrate-free structures using moulds and master templates, e.g. for hot-embossing
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A61M2037/003—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles having a lumen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A61M2037/0053—Methods for producing microneedles
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C45/00—Injection moulding, i.e. forcing the required volume of moulding material through a nozzle into a closed mould; Apparatus therefor
    • B29C2045/0094—Injection moulding, i.e. forcing the required volume of moulding material through a nozzle into a closed mould; Apparatus therefor injection moulding of small-sized articles, e.g. microarticles, ultra thin articles
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B81—MICROSTRUCTURAL TECHNOLOGY
    • B81B—MICROSTRUCTURAL DEVICES OR SYSTEMS, e.g. MICROMECHANICAL DEVICES
    • B81B2201/00—Specific applications of microelectromechanical systems
    • B81B2201/05—Microfluidics
    • B81B2201/055—Microneedles
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B81—MICROSTRUCTURAL TECHNOLOGY
    • B81B—MICROSTRUCTURAL DEVICES OR SYSTEMS, e.g. MICROMECHANICAL DEVICES
    • B81B2203/00—Basic microelectromechanical structures
    • B81B2203/03—Static structures
    • B81B2203/0361—Tips, pillars
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B81—MICROSTRUCTURAL TECHNOLOGY
    • B81C—PROCESSES OR APPARATUS SPECIALLY ADAPTED FOR THE MANUFACTURE OR TREATMENT OF MICROSTRUCTURAL DEVICES OR SYSTEMS
    • B81C2201/00—Manufacture or treatment of microstructural devices or systems
    • B81C2201/03—Processes for manufacturing substrate-free structures
    • B81C2201/034—Moulding

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Dermatology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Manufacturing & Machinery (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Mechanical Engineering (AREA)
  • Medical Informatics (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Microelectronics & Electronic Packaging (AREA)
  • Moulds For Moulding Plastics Or The Like (AREA)
  • Medicinal Preparation (AREA)
SE0402100A 2004-08-30 2004-08-30 Molded micro-needles SE0402100D0 (sv)

Priority Applications (7)

Application Number Priority Date Filing Date Title
SE0402100A SE0402100D0 (sv) 2004-08-30 2004-08-30 Molded micro-needles
AT05776430T ATE444096T1 (de) 2004-08-30 2005-08-30 Verfahren zur herstellung von geformten mikronadeln
EP05776430A EP1796778B1 (de) 2004-08-30 2005-08-30 Verfahren zur Herstellung von geformten Mikronadeln
US11/661,113 US7981346B2 (en) 2004-08-30 2005-08-30 Molded micro-needles
DE602005016951T DE602005016951D1 (de) 2004-08-30 2005-08-30 Verfahren zur Herstellung von geformten Mikronadeln
JP2007529775A JP2008511382A (ja) 2004-08-30 2005-08-30 成形微小針
PCT/SE2005/001260 WO2006025786A1 (en) 2004-08-30 2005-08-30 Molded micro-needles

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE0402100A SE0402100D0 (sv) 2004-08-30 2004-08-30 Molded micro-needles

Publications (1)

Publication Number Publication Date
SE0402100D0 true SE0402100D0 (sv) 2004-08-30

Family

ID=33096051

Family Applications (1)

Application Number Title Priority Date Filing Date
SE0402100A SE0402100D0 (sv) 2004-08-30 2004-08-30 Molded micro-needles

Country Status (7)

Country Link
US (1) US7981346B2 (de)
EP (1) EP1796778B1 (de)
JP (1) JP2008511382A (de)
AT (1) ATE444096T1 (de)
DE (1) DE602005016951D1 (de)
SE (1) SE0402100D0 (de)
WO (1) WO2006025786A1 (de)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1732640A4 (de) * 2004-03-12 2010-09-01 Agency Science Tech & Res Verfahren und formen zur verwendung bei der herstellung von mikronadeln mit seitenöffnungen
GB0616411D0 (en) * 2006-08-18 2006-09-27 Renishaw Plc Neurosurgical instruments
JP2010502267A (ja) * 2006-08-28 2010-01-28 エージェンシー・フォー・サイエンス・テクノロジー・アンド・リサーチ マイクロニードルおよびマイクロニードルの製造方法
WO2008036043A1 (en) * 2006-09-18 2008-03-27 Agency For Science, Technology And Research Needle structures and methods for fabricating needle structures
US7713196B2 (en) * 2007-03-09 2010-05-11 Nellcor Puritan Bennett Llc Method for evaluating skin hydration and fluid compartmentalization
DE102008052749B4 (de) * 2008-10-22 2012-01-12 Hahn-Schickard-Gesellschaft für angewandte Forschung e.V. Nadel, Nadelanordnung, Spritzgussform und Verfahren zum Herstellen
FI20095433A0 (fi) * 2009-04-20 2009-04-20 Valtion Teknillinen Mikroneula
EP2275164A1 (de) * 2009-07-15 2011-01-19 Debiotech S.A. Mikronadeln mit mehreren Kanälen
EP2563455A4 (de) 2010-04-28 2014-02-19 Kimberly Clark Co Verfahren zur erhöhung der durchlässigkeit einer epithelialbarriere
KR20130058012A (ko) 2010-04-28 2013-06-03 킴벌리-클라크 월드와이드, 인크. 사출 성형된 마이크로니들 어레이 및 마이크로니들 어레이의 형성 방법
WO2011135531A2 (en) 2010-04-28 2011-11-03 Kimberly-Clark Worldwide, Inc. MEDICAL DEVICES FOR DELIVERY OF siRNA
MX345837B (es) 2010-04-28 2017-02-16 Kimberly-Clark Worldwide Incorporated Dispositivo para la entrega de un medicamento para la artritis reumatoide.
JP6535464B2 (ja) 2011-10-27 2019-06-26 ソレント・セラピューティクス・インコーポレイテッド 生理活性薬剤の送達のための移植可能な装置
MX343262B (es) 2011-10-27 2016-10-28 Kimberly Clark Co Administración transdérmica de agentes bioactivos de alta viscosidad.
US20170246439A9 (en) 2011-10-27 2017-08-31 Kimberly-Clark Worldwide, Inc. Increased Bioavailability of Transdermally Delivered Agents
JP6155539B2 (ja) * 2011-12-02 2017-07-05 凸版印刷株式会社 針状体の製造方法および針状体の転写版
JP5856475B2 (ja) * 2011-12-28 2016-02-09 Asti株式会社 マイクロニードルの製造方法
EP2662110A1 (de) 2012-05-10 2013-11-13 Debiotech S.A. Vorrichtung und Methode für das Einsetzen von Nadeln
EP3021931B1 (de) 2013-07-16 2021-09-01 Kindeva Drug Delivery L.P. Hohlmikronadelfeldartikel
ES2871105T3 (es) 2013-07-16 2021-10-28 Kindeva Drug Delivery Lp Artículo que comprende una microaguja
EP3021930B1 (de) 2013-07-16 2020-10-07 3M Innovative Properties Company Hohle mikronadel mit abgeschrägter spitze
JP6430501B2 (ja) * 2013-07-16 2018-11-28 スリーエム イノベイティブ プロパティズ カンパニー 斜角開口部を有する中空マイクロニードル
KR102012241B1 (ko) 2017-08-30 2019-08-21 한국기계연구원 마이크로니들 구조체, 이의 제조방법 및 장치
KR102240614B1 (ko) * 2018-06-22 2021-04-16 주식회사 에스엔비아 화살촉 형상의 마이크로니들
WO2020256198A1 (ko) * 2019-06-21 2020-12-24 주식회사 에스엔비아 화살촉 형상의 마이크로니들 및 그 제조장치와 제조방법

Family Cites Families (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4838877A (en) * 1985-08-06 1989-06-13 Massau Bruce A Polymeric hypodermic device
US6573256B2 (en) 1996-12-30 2003-06-03 Bone Care International, Inc. Method of inhibiting angiogenesis using active vitamin D analogues
AU767122B2 (en) * 1998-06-10 2003-10-30 Georgia Tech Research Corporation Microneedle devices and methods of manufacture and use thereof
US6719719B2 (en) * 1998-11-13 2004-04-13 Elan Pharma International Limited Spike for liquid transfer device, liquid transfer device including spike, and method of transferring liquids using the same
AU2189400A (en) 1998-12-18 2000-07-03 Minimed, Inc. Insertion sets with micro-piercing members for use with medical devices and methods of using the same
US6743211B1 (en) * 1999-11-23 2004-06-01 Georgia Tech Research Corporation Devices and methods for enhanced microneedle penetration of biological barriers
US6312612B1 (en) * 1999-06-09 2001-11-06 The Procter & Gamble Company Apparatus and method for manufacturing an intracutaneous microneedle array
US6379324B1 (en) * 1999-06-09 2002-04-30 The Procter & Gamble Company Intracutaneous microneedle array apparatus
US6629949B1 (en) 2000-05-08 2003-10-07 Sterling Medivations, Inc. Micro infusion drug delivery device
EP1345646A2 (de) * 2000-12-14 2003-09-24 Georgia Tech Research Corporation Mikronadel-vorrichtungen und deren herstellung
US6767341B2 (en) * 2001-06-13 2004-07-27 Abbott Laboratories Microneedles for minimally invasive drug delivery
US6749792B2 (en) * 2001-07-09 2004-06-15 Lifescan, Inc. Micro-needles and methods of manufacture and use thereof
SE0102736D0 (sv) 2001-08-14 2001-08-14 Patrick Griss Side opened out-of-plane microneedles for microfluidic transdermal interfacing and fabrication process of side opened out-of-plane microneedles
US6881203B2 (en) * 2001-09-05 2005-04-19 3M Innovative Properties Company Microneedle arrays and methods of manufacturing the same
AU2002327675A1 (en) * 2001-09-19 2003-04-01 Biovalve Technologies, Inc. Microneedles, microneedle arrays, and systems and methods relating to same
AU2002343457A1 (en) * 2001-09-28 2003-04-07 Biovalve Technologies, Inc. Switchable microneedle arrays and systems and methods relating to same
CN1662266A (zh) * 2001-10-29 2005-08-31 贝克顿迪肯森公司 输送物质的方法和装置
WO2003048031A2 (en) * 2001-11-30 2003-06-12 Alza Corporation Methods and apparatuses for forming microprojection arrays
CA2478822C (en) * 2002-03-11 2016-07-12 Passport Technologies, Inc. Transdermal drug delivery patch system, method of making same and method of using same
US6899838B2 (en) * 2002-07-12 2005-05-31 Becton, Dickinson And Company Method of forming a mold and molding a micro-device
US20040106904A1 (en) * 2002-10-07 2004-06-03 Gonnelli Robert R. Microneedle array patch
US7578954B2 (en) * 2003-02-24 2009-08-25 Corium International, Inc. Method for manufacturing microstructures having multiple microelements with through-holes
ES2290738T3 (es) * 2003-06-30 2008-02-16 Alza Corporation Procedimiento para revestir microproyecciones de perforacion de la piel.

Also Published As

Publication number Publication date
US7981346B2 (en) 2011-07-19
WO2006025786A1 (en) 2006-03-09
JP2008511382A (ja) 2008-04-17
US20070255205A1 (en) 2007-11-01
ATE444096T1 (de) 2009-10-15
DE602005016951D1 (de) 2009-11-12
EP1796778A1 (de) 2007-06-20
EP1796778B1 (de) 2009-09-30

Similar Documents

Publication Publication Date Title
DE602005016951D1 (de) Verfahren zur Herstellung von geformten Mikronadeln
BRPI0509773A (pt) preformas, garrafas e método para fabricar as preformas e as garrafas
WO2008084230A3 (en) Injection mould and injection moulding method
MX2009003502A (es) Proceso para producir un cuerpo hueco plastico a partir de una preforma y boquilla para extruir una preforma.
EP2020283A4 (de) Formwerkzeug zum formen von thermoplastischem harz, hohlraumformwerkzeug und verfahren zur herstellung des hohlraumformwerkzeugs
BRPI0515214A (pt) molde para moldagem por injeção, processo para fabricar uma peça de matéria plástica e peça de matéria plástica
ATE489217T1 (de) Formen von kunststoffartikeln
DE602004029427D1 (de) Blasformverfahren
ES2495100T3 (es) Un molde para el moldeo por inyección de elementos con cortes sesgados fabricados de plástico, con un sistema de inyección integrado
MX382602B (es) Portón trasero para vehículo.
CN202952492U (zh) 排气机构
BRPI0509395A (pt) conjunto de preformado, conjunto de recipiente, e método de fabricação
MX2019005338A (es) Metodo de manufactura mediante inyeccion de una parte hecha de un material plastico que incluye una superficie tecnica y que incorpora un elemento de refuerzo.
MX2007004544A (es) Aparato y metodo para manufacturar productos de plastico.
WO2006039309A3 (en) A molded, plastic container and a method for making the same
DE50306776D1 (de) Verfahren zum herstellen von hinterspritzten kunststoffformteilen
PL1888316T3 (pl) Sposób kontroli procesu wtryskiwania we wtryskarce
SE0200195D0 (sv) Förfarande och anordning för framställning av plastdetaljer
EA200701878A1 (ru) Способ формирования соединительных средств на пластиковых контейнерах, получаемых посредством экструзии и формирования дутьем, а также используемая для этого форма
WO2005084487A3 (en) Injection moulding process
CN203622844U (zh) 一种聚氨酯产品模具的排气结构
WO2012135678A3 (en) Injection blow moulding apparatus and method
US20170334121A1 (en) Method for making a hard luggage case
CN207509644U (zh) 带孔球面模具脱模结构
WO2009019301A3 (en) Process and die for manufacturing a plastic hollow body