SE431545B - Forfarande for framstellning av nya 2-substituerade oxazolopyridiner - Google Patents

Forfarande for framstellning av nya 2-substituerade oxazolopyridiner

Info

Publication number
SE431545B
SE431545B SE7608037A SE7608037A SE431545B SE 431545 B SE431545 B SE 431545B SE 7608037 A SE7608037 A SE 7608037A SE 7608037 A SE7608037 A SE 7608037A SE 431545 B SE431545 B SE 431545B
Authority
SE
Sweden
Prior art keywords
oxazolopyridines
substituted
procedure
preparation
new
Prior art date
Application number
SE7608037A
Other languages
English (en)
Swedish (sv)
Other versions
SE7608037L (sv
Inventor
N P Jensen
Original Assignee
Merck & Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck & Co Inc filed Critical Merck & Co Inc
Publication of SE7608037L publication Critical patent/SE7608037L/xx
Publication of SE431545B publication Critical patent/SE431545B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/72—Nitrogen atoms
    • C07D213/73—Unsubstituted amino or imino radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C205/00—Compounds containing nitro groups bound to a carbon skeleton
    • C07C205/49—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by carboxyl groups
    • C07C205/57—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by carboxyl groups having nitro groups and carboxyl groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C63/00—Compounds having carboxyl groups bound to a carbon atoms of six-membered aromatic rings
    • C07C63/68—Compounds having carboxyl groups bound to a carbon atoms of six-membered aromatic rings containing halogen
    • C07C63/72—Polycyclic acids

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
SE7608037A 1975-07-29 1976-07-14 Forfarande for framstellning av nya 2-substituerade oxazolopyridiner SE431545B (sv)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/600,169 US4011326A (en) 1975-07-29 1975-07-29 2-Substituted oxazolo[4,5-b]pyridine anti-inflammatory agents

Publications (2)

Publication Number Publication Date
SE7608037L SE7608037L (sv) 1977-01-30
SE431545B true SE431545B (sv) 1984-02-13

Family

ID=24402575

Family Applications (1)

Application Number Title Priority Date Filing Date
SE7608037A SE431545B (sv) 1975-07-29 1976-07-14 Forfarande for framstellning av nya 2-substituerade oxazolopyridiner

Country Status (14)

Country Link
US (1) US4011326A (fr)
JP (1) JPS6037116B2 (fr)
AU (1) AU505159B2 (fr)
BE (1) BE844577A (fr)
CH (1) CH603661A5 (fr)
DE (1) DE2633905A1 (fr)
DK (1) DK320276A (fr)
ES (1) ES450245A1 (fr)
FR (1) FR2319354A1 (fr)
GB (1) GB1497985A (fr)
HU (1) HU172167B (fr)
NL (1) NL7607794A (fr)
SE (1) SE431545B (fr)
ZA (1) ZA764527B (fr)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH085368Y2 (ja) * 1987-03-05 1996-02-14 日産自動車株式会社 内燃機関のコネクティングロッド
DE59711147D1 (de) * 1996-11-11 2004-01-29 Altana Pharma Ag Neue Imidazo- und Oxazolopyridine als Phosphodiesterase Inhibitoren.
ME01310B (fr) 2001-05-15 2011-10-10 Hoffmann La Roche Derives d'oxazole substitues par de l'acide carboxylique utiles en tant qu'activateurs ppar-alpha et gamma dans le traitement du diabete
AU2002322720B2 (en) 2001-07-25 2008-11-13 Raptor Pharmaceutical Inc. Compositions and methods for modulating blood-brain barrier transport
ATE372990T1 (de) * 2002-07-03 2007-09-15 Hoffmann La Roche Oxazolderivat und deren verwendung als insulinsensibilisatoren
CN100475810C (zh) * 2002-08-30 2009-04-08 霍夫曼-拉罗奇有限公司 作为PPARα和PPARγ激动剂的新型2-芳基噻唑化合物
NZ537979A (en) * 2002-09-12 2007-08-31 Hoffmann La Roche N-substituted-1H-indol-5-propionic acid compounds as PPAR agonists useful for the treatment of diabetes
MXPA05005445A (es) * 2002-11-25 2005-08-26 Hoffmann La Roche Derivados de indolilo.
CN102379684B (zh) 2005-04-28 2014-11-19 普罗透斯数字保健公司 药物信息系统
KR20090071598A (ko) 2006-09-18 2009-07-01 랩터 파마슈티컬 인코포레이티드 수용체 결합 단백질(rap)-접합체 투여에 의한 간 질환의 치료
EP2398500B1 (fr) 2009-02-20 2019-03-13 2-BBB Medicines B.V. Sustème d'administration de médicament à base de glutathionne
ES2942923T3 (es) 2009-05-06 2023-06-07 Laboratory Skin Care Inc Composiciones de administración dérmica que comprenden complejos de agente activo-partículas de fosfato de calcio y métodos de uso de las mismas
US20120077778A1 (en) 2010-09-29 2012-03-29 Andrea Bourdelais Ladder-Frame Polyether Conjugates

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3935195A (en) * 1969-04-28 1976-01-27 Sterling Drug Inc. 4,4'-Stilbenebis-pyridooxazoles and related optical brighteners and polymeric compositions brightened thereby
FR2148362A1 (en) * 1971-08-11 1973-03-23 Ferlux 2-amino-(4,5-b)-oxazolopyridine cpds - with analgesic,anti-inflammato anticonvulsant,muscle relaxant and diuretic activity
AR208500A1 (es) * 1972-06-14 1977-02-15 Merck & Co Inc Procedimiento para la preparacion de derivados de oxazolo(4,5-b)-piridinas

Also Published As

Publication number Publication date
BE844577A (fr) 1977-01-28
JPS5217495A (en) 1977-02-09
SE7608037L (sv) 1977-01-30
AU1605276A (en) 1978-01-26
ZA764527B (en) 1978-03-29
DE2633905A1 (de) 1977-02-17
DK320276A (da) 1977-01-30
ES450245A1 (es) 1979-05-16
CH603661A5 (fr) 1978-08-31
AU505159B2 (en) 1979-11-08
US4011326A (en) 1977-03-08
JPS6037116B2 (ja) 1985-08-24
NL7607794A (nl) 1977-02-01
GB1497985A (en) 1978-01-12
FR2319354A1 (fr) 1977-02-25
HU172167B (hu) 1978-06-28
FR2319354B1 (fr) 1979-07-20

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