SE442304B - Forfarande for framstellning av en lett plasminkedja med ett serinproteasaktivt centrum - Google Patents

Forfarande for framstellning av en lett plasminkedja med ett serinproteasaktivt centrum

Info

Publication number: SE442304B
Authority: SE; Sweden
Prior art keywords: procedure; preparation; active center; protein active; light plasma
Prior art date: 1976-09-24

Application number

SE7710653A

Other languages

English (en)

Swedish (sv)

Other versions

SE7710653L (sv

Inventor

K C Robbins

L Summaria

Original Assignee

Reese Res Found

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1976-09-24

Filing date

1977-09-22

Publication date

1985-12-16

1977-09-22 Application filed by Reese Res Found filed Critical Reese Res Found

1978-03-25 Publication of SE7710653L publication Critical patent/SE7710653L/xx

1985-12-16 Publication of SE442304B publication Critical patent/SE442304B/xx

Links

MTCFGRXMJLQNBG-UHFFFAOYSA-N Serine Natural products OCC(N)C(O)=O MTCFGRXMJLQNBG-UHFFFAOYSA-N 0.000 title 1
102000004169 proteins and genes Human genes 0.000 title 1
108090000623 proteins and genes Proteins 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
- C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
- C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
- C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
- C12N9/6424—Serine endopeptidases (3.4.21)
- C12N9/6435—Plasmin (3.4.21.7), i.e. fibrinolysin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
- C12Y304/21—Serine endopeptidases (3.4.21)
- C12Y304/21007—Plasmin (3.4.21.7), i.e. fibrinolysin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Engineering & Computer Science (AREA)
Organic Chemistry (AREA)
Bioinformatics & Cheminformatics (AREA)
Wood Science & Technology (AREA)
Zoology (AREA)
Genetics & Genomics (AREA)
General Health & Medical Sciences (AREA)
Biochemistry (AREA)
General Engineering & Computer Science (AREA)
Biomedical Technology (AREA)
Medicinal Chemistry (AREA)
Microbiology (AREA)
Biotechnology (AREA)
Molecular Biology (AREA)
Chemical Kinetics & Catalysis (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Hematology (AREA)
Diabetes (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Enzymes And Modification Thereof (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)

SE7710653A 1976-09-24 1977-09-22 Forfarande for framstellning av en lett plasminkedja med ett serinproteasaktivt centrum SE442304B (sv)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US05/726,142 US4082612A (en)	1976-09-24	1976-09-24	Plasminogen activator complex

Publications (2)

Publication Number	Publication Date
SE7710653L SE7710653L (sv)	1978-03-25
SE442304B true SE442304B (sv)	1985-12-16

Family

ID=24917422

Family Applications (3)

Application Number	Title	Priority Date	Filing Date
SE7710653A SE442304B (sv)	1976-09-24	1977-09-22	Forfarande for framstellning av en lett plasminkedja med ett serinproteasaktivt centrum
SE8301795A SE454048B (sv)	1976-09-24	1983-03-30	Forfarande for framstellning av ett komplex av streptokinas och en lett plasminkedja med ett serinproteasaktivt centrum
SE8301794A SE454047B (sv)	1976-09-24	1983-03-30	Forfarande for framstellning av ett komplex av streptokinas och en lett plasminkedja med ett serinproteasaktivt centrum

Family Applications After (2)

Application Number	Title	Priority Date	Filing Date
SE8301795A SE454048B (sv)	1976-09-24	1983-03-30	Forfarande for framstellning av ett komplex av streptokinas och en lett plasminkedja med ett serinproteasaktivt centrum
SE8301794A SE454047B (sv)	1976-09-24	1983-03-30	Forfarande for framstellning av ett komplex av streptokinas och en lett plasminkedja med ett serinproteasaktivt centrum

Country Status (10)

Country	Link
US (1)	US4082612A (2)
JP (1)	JPS5352606A (2)
CA (1)	CA1094449A (2)
CH (2)	CH637991A5 (2)
DE (1)	DE2742529C2 (2)
DK (1)	DK421577A (2)
FR (1)	FR2365583A1 (2)
GB (1)	GB1533205A (2)
NL (1)	NL7710451A (2)
SE (3)	SE442304B (2)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP0028489B1 (en) *	1979-11-05	1983-10-05	Beecham Group Plc	Enzyme derivatives, and their preparation
JPS58189122A (ja) *	1982-04-30	1983-11-04	Kaken Pharmaceut Co Ltd	高脂血症予防治療剤
US4536391A (en) *	1982-11-17	1985-08-20	Otsuka Pharmaceutical Co.	Process for preparing urokinase complex
JPS60136520A (ja) *	1983-12-23	1985-07-20	Otsuka Pharmaceut Co Ltd	フイブリン吸着性ウロキナ−ゼ複合体
US4880776A (en) *	1983-12-24	1989-11-14	Beecham Group P.L.C.	Plasmin A-chain urokinase B-chain hybrid protein
GB8334498D0 (en) *	1983-12-24	1984-02-01	Beecham Group Plc	Compounds
GB8334499D0 (en) *	1983-12-24	1984-02-01	Beecham Group Plc	Derivatives
GB8400653D0 (en) *	1984-01-11	1984-02-15	Beecham Group Plc	Conjugates
DE3584902D1 (de) *	1984-02-29	1992-01-30	Asahi Chemical Ind	Waessrige loesung eines darin in erhoehter konzentration aufgeloesten gewebe-plasminogen-aktivators und herstellungsverfahren.
US4774087A (en) *	1987-08-14	1988-09-27	Northwestern University	Micro-size fibrinolytic plasmin
DE3833936C1 (2) *	1988-10-05	1989-09-21	Henning Berlin Gmbh Chemie- Und Pharmawerk, 1000 Berlin, De
US6964764B2 (en) *	1999-11-13	2005-11-15	Talecris Biotherapeutics, Inc.	Method of thrombolysis by local delivery of reversibly inactivated acidified plasmin
US6355243B1 (en) *	1999-11-13	2002-03-12	Bayer Corporation	Method of thrombolysis by local delivery of active plasmin
US7544500B2 (en) *	1999-11-13	2009-06-09	Talecris Biotherapeutics, Inc.	Process for the production of a reversibly inactive acidified plasmin composition
US6969515B2 (en)	1999-11-13	2005-11-29	Talecris Biotherapeutics, Inc.	Method of thrombolysis by local delivery of reversibly inactivated acidified plasmin
WO2009149199A2 (en) *	2008-06-04	2009-12-10	Talecris Biotherapeutics, Inc.	Composition, method and kit for preparing plasmin
PT2403865E (pt)	2009-03-03	2015-11-18	Grifols Therapeutics Inc	Métodos de preparação de plasminogénio

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3865692A (en) *	1974-01-11	1975-02-11	Abbott Lab	Method for making highly potent plasminogen

1976
- 1976-09-24 US US05/726,142 patent/US4082612A/en not_active Expired - Lifetime
1977
- 1977-08-16 CA CA284,760A patent/CA1094449A/en not_active Expired
- 1977-09-19 GB GB38933/77A patent/GB1533205A/en not_active Expired
- 1977-09-21 DE DE2742529A patent/DE2742529C2/de not_active Expired
- 1977-09-21 JP JP11276977A patent/JPS5352606A/ja active Pending
- 1977-09-22 SE SE7710653A patent/SE442304B/xx not_active IP Right Cessation
- 1977-09-22 FR FR7728611A patent/FR2365583A1/fr active Granted
- 1977-09-23 NL NL7710451A patent/NL7710451A/xx not_active Application Discontinuation
- 1977-09-23 CH CH1165677A patent/CH637991A5/de not_active IP Right Cessation
- 1977-09-23 DK DK421577A patent/DK421577A/da not_active Application Discontinuation
1982
- 1982-08-27 CH CH511282A patent/CH637992A5/de not_active IP Right Cessation
1983
- 1983-03-30 SE SE8301795A patent/SE454048B/sv not_active IP Right Cessation
- 1983-03-30 SE SE8301794A patent/SE454047B/sv not_active IP Right Cessation

Also Published As

Publication number	Publication date
DK421577A (da)	1978-03-25
SE8301795D0 (sv)	1983-03-30
DE2742529C2 (de)	1984-01-05
CH637992A5 (de)	1983-08-31
JPS5352606A (en)	1978-05-13
NL7710451A (nl)	1978-03-29
US4082612A (en)	1978-04-04
SE8301794D0 (sv)	1983-03-30
FR2365583B1 (2)	1981-07-10
SE7710653L (sv)	1978-03-25
SE8301795L (sv)	1983-03-30
CA1094449A (en)	1981-01-27
DE2742529A1 (de)	1978-03-30
GB1533205A (en)	1978-11-22
SE454048B (sv)	1988-03-28
FR2365583A1 (fr)	1978-04-21
CH637991A5 (de)	1983-08-31
SE454047B (sv)	1988-03-28

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Legal Events

Date

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Title

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1995-01-31

NUG

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