SE455445B - Antikroppar mot sialosyllaktotetraos (iv?723neuaclcose?714) och antikroppens resp antigenets anvendning vid tumordiagnostik - Google Patents

Antikroppar mot sialosyllaktotetraos (iv?723neuaclcose?714) och antikroppens resp antigenets anvendning vid tumordiagnostik

Info

Publication number
SE455445B
SE455445B SE8404283A SE8404283A SE455445B SE 455445 B SE455445 B SE 455445B SE 8404283 A SE8404283 A SE 8404283A SE 8404283 A SE8404283 A SE 8404283A SE 455445 B SE455445 B SE 455445B
Authority
SE
Sweden
Prior art keywords
antigen
methanol
water
sialosyllactotetraose
use according
Prior art date
Application number
SE8404283A
Other languages
English (en)
Swedish (sv)
Other versions
SE8404283L (sv
SE8404283D0 (sv
Inventor
J R Holmgren
L G Lindholm
L T Svennerholm
Original Assignee
Pharmacia Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pharmacia Ab filed Critical Pharmacia Ab
Priority to SE8404283A priority Critical patent/SE455445B/sv
Publication of SE8404283D0 publication Critical patent/SE8404283D0/xx
Priority to DE8585850256T priority patent/DE3585061D1/de
Priority to AT85850256T priority patent/ATE71225T1/de
Priority to EP85850256A priority patent/EP0173663B1/de
Priority to JP60186757A priority patent/JPH0690204B2/ja
Publication of SE8404283L publication Critical patent/SE8404283L/
Publication of SE455445B publication Critical patent/SE455445B/sv

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04Organic compounds
    • A61K51/08Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
    • A61K51/10Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody
    • A61K51/1045Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody against animal or human tumor cells or tumor cell determinants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2123/00Preparations for testing in vivo
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Biophysics (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Optics & Photonics (AREA)
  • Public Health (AREA)
  • Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Biochemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Oncology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
SE8404283A 1984-08-28 1984-08-28 Antikroppar mot sialosyllaktotetraos (iv?723neuaclcose?714) och antikroppens resp antigenets anvendning vid tumordiagnostik SE455445B (sv)

Priority Applications (5)

Application Number Priority Date Filing Date Title
SE8404283A SE455445B (sv) 1984-08-28 1984-08-28 Antikroppar mot sialosyllaktotetraos (iv?723neuaclcose?714) och antikroppens resp antigenets anvendning vid tumordiagnostik
DE8585850256T DE3585061D1 (de) 1984-08-28 1985-08-06 Verwendung eines spezifischen tumorassoziierten antigens, sialosyllactotetraose, in diagnose- oder therapieverfahren bezueglich krebskrankheiten.
AT85850256T ATE71225T1 (de) 1984-08-28 1985-08-06 Verwendung eines spezifischen tumorassoziierten antigens, sialosyllactotetraose, in diagnoseoder therapieverfahren bezueglich krebskrankheiten.
EP85850256A EP0173663B1 (de) 1984-08-28 1985-08-06 Verwendung eines spezifischen tumorassoziierten Antigens, Sialosyllactotetraose, in Diagnose- oder Therapieverfahren bezüglich Krebskrankheiten
JP60186757A JPH0690204B2 (ja) 1984-08-28 1985-08-27 腫瘍に関連した特殊な抗原シアロシルラクトテトラオースに特異的な抗体

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE8404283A SE455445B (sv) 1984-08-28 1984-08-28 Antikroppar mot sialosyllaktotetraos (iv?723neuaclcose?714) och antikroppens resp antigenets anvendning vid tumordiagnostik

Publications (3)

Publication Number Publication Date
SE8404283D0 SE8404283D0 (sv) 1984-08-28
SE8404283L SE8404283L (sv) 1986-03-01
SE455445B true SE455445B (sv) 1988-07-11

Family

ID=20356831

Family Applications (1)

Application Number Title Priority Date Filing Date
SE8404283A SE455445B (sv) 1984-08-28 1984-08-28 Antikroppar mot sialosyllaktotetraos (iv?723neuaclcose?714) och antikroppens resp antigenets anvendning vid tumordiagnostik

Country Status (5)

Country Link
EP (1) EP0173663B1 (de)
JP (1) JPH0690204B2 (de)
AT (1) ATE71225T1 (de)
DE (1) DE3585061D1 (de)
SE (1) SE455445B (de)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0287916A1 (de) * 1987-04-13 1988-10-26 Otsuka Pharmaceutical Co., Ltd. Immunoassay
US5079353A (en) * 1987-12-02 1992-01-07 Chembiomed, Ltd. Sialic acid glycosides, antigens, immunoadsorbents, and methods for their preparation
EP0380084A3 (de) * 1989-01-27 1991-03-13 The Biomembrane Institute Methode zur Hemmung dvon Zell-Zell- und Zellsubstrat-Wechselwirkungen durch Blockierung der Kohlenhydrat-Kohlenhydrat-Wechselwirkungen
WO1990010708A1 (en) * 1989-03-09 1990-09-20 The Sendai Institute Of Microbiology Monoclonal antibody, and assay method, reagent kit, search method and drug missile using said antibody
CA2432978C (en) * 2000-12-22 2012-08-28 Medlyte, Inc. Compositions and methods for the treatment and prevention of cardiovascular diseases and disorders, and for identifying agents therapeutic therefor
US9274130B2 (en) 2006-05-31 2016-03-01 Lpath, Inc. Prevention and treatment of pain using antibodies to lysophosphatidic acid
US8796429B2 (en) 2006-05-31 2014-08-05 Lpath, Inc. Bioactive lipid derivatives, and methods of making and using same
US7862812B2 (en) 2006-05-31 2011-01-04 Lpath, Inc. Methods for decreasing immune response and treating immune conditions
US9274129B2 (en) 2006-05-31 2016-03-01 Lpath, Inc. Methods and reagents for detecting bioactive lipids
US9217749B2 (en) 2006-05-31 2015-12-22 Lpath, Inc. Immune-derived moieties reactive against lysophosphatidic acid
US8614103B2 (en) 2006-10-27 2013-12-24 Lpath, Inc. Compositions and methods for treating sphingosine-1-phosphate (S1P) related ocular diseases and conditions
PL2087002T3 (pl) 2006-10-27 2015-02-27 Lpath Inc Kompozycje i sposoby do wiązania sfingozyno-1 fosforanu
US8361465B2 (en) 2007-10-26 2013-01-29 Lpath, Inc. Use of anti-sphingosine-1-phosphate antibodies in combination with chemotherapeutic agents
US8871202B2 (en) 2008-10-24 2014-10-28 Lpath, Inc. Prevention and treatment of pain using antibodies to sphingosine-1-phosphate

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4471057A (en) * 1981-06-30 1984-09-11 The Wistar Institute Detection of colorectal carcinoma
ATE56046T1 (de) * 1983-03-04 1990-09-15 Health Research Inc Monoklonale antikoerper gegen humane brustkarzinomzellen und ihre verwendung in der diagnose und therapie.
US4569788A (en) * 1983-05-18 1986-02-11 The United States Of America As Represented By The Department Of Health And Human Services Monoclonal antibodies against non small cell lung cancer

Also Published As

Publication number Publication date
ATE71225T1 (de) 1992-01-15
SE8404283L (sv) 1986-03-01
EP0173663A2 (de) 1986-03-05
SE8404283D0 (sv) 1984-08-28
DE3585061D1 (de) 1992-02-13
EP0173663B1 (de) 1992-01-02
JPS61116660A (ja) 1986-06-04
JPH0690204B2 (ja) 1994-11-14
EP0173663A3 (en) 1987-10-07

Similar Documents

Publication Publication Date Title
Westberg et al. Human glomerular basement membrane. Preparation and composition
Fredman et al. Monoclonal antibody A2B5 reacts with many gangliosides in neuronal tissue
J Eichberg et al. Distribution of lipids in subcellular particles of guinea-pig brain
Ångström et al. The lactosylceramide binding specificity of Helicobacter pylori
SE455445B (sv) Antikroppar mot sialosyllaktotetraos (iv?723neuaclcose?714) och antikroppens resp antigenets anvendning vid tumordiagnostik
MAKITA et al. Chemical and immunological characterization of the Forssman hapten isolated from equine organs
Siddiqui et al. Differential expression of ganglioside GD3 by human leukocytes and leukemia cells
Marcus et al. Localization of glycosphingolipids in human tissues by immunofluorescence
Franz Advances in Lectin Research: Volume 4
Magnani et al. [14] Antibodies against cell surface carbohydrates: Determination of antigen structure
Cooper et al. In vivo release of glycoprotein I from the Ha subline of TA3 murine tumor into ascites fluid and serum
Springer et al. Blood group Tn-active macromolecules from human carcinomas and erythrocytes: characterization of and specific reactivity with mono-and poly-clonal anti-Tn antibodies induced by various immunogens
US4757003A (en) Method for the detection of cancer
EP0395217A2 (de) Bio-organische Synthese von dimerem LeX (difucosyl y2; III3FucV3FucnLc6Cer) und Analogen hiervon
Marcus Isolation of a substance with blood‐group P1 activity from human erythrocyte stroma
Deal et al. Lacto-and ganglio-series glycolipids are adhesion receptors for Neisseria gonorrhoeae.
JPH06501383A (ja) 病原体又は日和見感染微生物に対する接着受容体
EP0162825B1 (de) Verwendung eines spezifischen karzinomassoziierenden Antigens (Hapten), Fucosylsialosylgangliotetrose (Fuc-GM1) in diagnostischen und therapeutischen Verfahren betreffend den menschlichen Lungenkrebs (Carcinomas von kleinen Zellen)
Miyakawa et al. Demonstration of human nephritogenic tubular antigen in the serum and organs by radioimmunoassay
Kundu et al. Aminopropyl silica gel as a solid support for preparation of glycolipid immunoadsorbent and purification of antibodies.
He et al. GD3 expression by cultured human tumor cells of neuroectodermal origin
US5011920A (en) Disialofucoganglioside immunogen and fucoganglioside monosialosyl Lea II
Harvey et al. Immunochemical studies on carcinoembryonic antigen-reactive glycoproteins from carcinomas of the colon and breast separated by concanavalin A affinity chromatography
Glickman et al. The apoproteins of various size classes of human chylous fluid lipoproteins
Esselman et al. Glycosphingolipids of membrane fractions from normal and transplanted canine kidney

Legal Events

Date Code Title Description
NAL Patent in force

Ref document number: 8404283-7

Format of ref document f/p: F

NUG Patent has lapsed