SE511373C2 - Beredning för behandling av aphte - Google Patents

Beredning för behandling av aphte

Info

Publication number: SE511373C2
Authority: SE; Sweden
Prior art keywords: weight; preparation; formulation; treatment; xylitol
Prior art date: 1997-12-19

Application number

SE9704789A

Other languages

English (en)

Swedish (sv)

Other versions

SE9704789L (sv

SE9704789D0 (sv

Inventor

Martin Nils Braennstroem

Kerstin Birgitta Orreby

Original Assignee

Dental Therapeutics Ab

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1997-12-19

Filing date

1997-12-19

Publication date

1999-09-20

1997-12-19 Application filed by Dental Therapeutics Ab filed Critical Dental Therapeutics Ab

1997-12-19 Priority to SE9704789A priority Critical patent/SE511373C2/sv

1997-12-19 Publication of SE9704789D0 publication Critical patent/SE9704789D0/xx

1998-12-17 Priority to PCT/SE1998/002366 priority patent/WO1999032132A1/fr

1998-12-17 Priority to AU19911/99A priority patent/AU1991199A/en

1999-06-20 Publication of SE9704789L publication Critical patent/SE9704789L/xx

1999-09-20 Publication of SE511373C2 publication Critical patent/SE511373C2/sv

Links

238000002360 preparation method Methods 0.000 title claims abstract description 25
TVXBFESIOXBWNM-UHFFFAOYSA-N Xylitol Natural products OCCC(O)C(O)C(O)CCO TVXBFESIOXBWNM-UHFFFAOYSA-N 0.000 claims abstract description 15
HEBKCHPVOIAQTA-UHFFFAOYSA-N meso ribitol Natural products OCC(O)C(O)C(O)CO HEBKCHPVOIAQTA-UHFFFAOYSA-N 0.000 claims abstract description 15
239000000811 xylitol Substances 0.000 claims abstract description 15
235000010447 xylitol Nutrition 0.000 claims abstract description 15
HEBKCHPVOIAQTA-SCDXWVJYSA-N xylitol Chemical compound OC[C@H](O)[C@@H](O)[C@H](O)CO HEBKCHPVOIAQTA-SCDXWVJYSA-N 0.000 claims abstract description 15
229960002675 xylitol Drugs 0.000 claims abstract description 15
239000004378 Glycyrrhizin Substances 0.000 claims abstract description 9
LPLVUJXQOOQHMX-UHFFFAOYSA-N glycyrrhetinic acid glycoside Natural products C1CC(C2C(C3(CCC4(C)CCC(C)(CC4C3=CC2=O)C(O)=O)C)(C)CC2)(C)C2C(C)(C)C1OC1OC(C(O)=O)C(O)C(O)C1OC1OC(C(O)=O)C(O)C(O)C1O LPLVUJXQOOQHMX-UHFFFAOYSA-N 0.000 claims abstract description 9
229960004949 glycyrrhizic acid Drugs 0.000 claims abstract description 9
UYRUBYNTXSDKQT-UHFFFAOYSA-N glycyrrhizic acid Natural products CC1(C)C(CCC2(C)C1CCC3(C)C2C(=O)C=C4C5CC(C)(CCC5(C)CCC34C)C(=O)O)OC6OC(C(O)C(O)C6OC7OC(O)C(O)C(O)C7C(=O)O)C(=O)O UYRUBYNTXSDKQT-UHFFFAOYSA-N 0.000 claims abstract description 9
235000019410 glycyrrhizin Nutrition 0.000 claims abstract description 9
LPLVUJXQOOQHMX-QWBHMCJMSA-N glycyrrhizinic acid Chemical compound O([C@@H]1[C@@H](O)[C@H](O)[C@H](O[C@@H]1O[C@@H]1C([C@H]2[C@]([C@@H]3[C@@]([C@@]4(CC[C@@]5(C)CC[C@@](C)(C[C@H]5C4=CC3=O)C(O)=O)C)(C)CC2)(C)CC1)(C)C)C(O)=O)[C@@H]1O[C@H](C(O)=O)[C@@H](O)[C@H](O)[C@H]1O LPLVUJXQOOQHMX-QWBHMCJMSA-N 0.000 claims abstract description 9
229940047648 cocoamphodiacetate Drugs 0.000 claims abstract description 6
239000006072 paste Substances 0.000 claims abstract description 4
239000002775 capsule Substances 0.000 claims abstract description 3
229940112822 chewing gum Drugs 0.000 claims abstract description 3
235000015218 chewing gum Nutrition 0.000 claims abstract description 3
239000002324 mouth wash Substances 0.000 claims abstract description 3
229940051866 mouthwash Drugs 0.000 claims abstract description 3
239000003826 tablet Substances 0.000 claims abstract description 3
239000000203 mixture Substances 0.000 claims description 18
238000009472 formulation Methods 0.000 claims description 11
PUZPDOWCWNUUKD-UHFFFAOYSA-M sodium fluoride Chemical compound [F-].[Na+] PUZPDOWCWNUUKD-UHFFFAOYSA-M 0.000 claims description 10
208000002399 aphthous stomatitis Diseases 0.000 claims description 8
239000000126 substance Substances 0.000 claims description 8
-1 polyethylene Polymers 0.000 claims description 7
VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 claims description 6
239000011775 sodium fluoride Substances 0.000 claims description 5
235000013024 sodium fluoride Nutrition 0.000 claims description 5
229940090248 4-hydroxybenzoic acid Drugs 0.000 claims description 4
FJKROLUGYXJWQN-UHFFFAOYSA-N papa-hydroxy-benzoic acid Natural products OC(=O)C1=CC=C(O)C=C1 FJKROLUGYXJWQN-UHFFFAOYSA-N 0.000 claims description 4
XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 4
229920002134 Carboxymethyl cellulose Polymers 0.000 claims description 3
239000004698 Polyethylene Substances 0.000 claims description 3
HVUMOYIDDBPOLL-XWVZOOPGSA-N Sorbitan monostearate Chemical compound CCCCCCCCCCCCCCCCCC(=O)OC[C@@H](O)[C@H]1OC[C@H](O)[C@H]1O HVUMOYIDDBPOLL-XWVZOOPGSA-N 0.000 claims description 3
239000001768 carboxy methyl cellulose Substances 0.000 claims description 3
235000010948 carboxy methyl cellulose Nutrition 0.000 claims description 3
239000008112 carboxymethyl-cellulose Substances 0.000 claims description 3
239000003795 chemical substances by application Substances 0.000 claims description 3
238000005498 polishing Methods 0.000 claims description 3
229920000573 polyethylene Polymers 0.000 claims description 3
239000000377 silicon dioxide Substances 0.000 claims description 3
239000001587 sorbitan monostearate Substances 0.000 claims description 3
235000011076 sorbitan monostearate Nutrition 0.000 claims description 3
229940035048 sorbitan monostearate Drugs 0.000 claims description 3
239000003814 drug Substances 0.000 claims description 2
239000003755 preservative agent Substances 0.000 claims 2
239000003995 emulsifying agent Substances 0.000 claims 1
239000002904 solvent Substances 0.000 claims 1
208000003265 stomatitis Diseases 0.000 abstract 1
239000000606 toothpaste Substances 0.000 description 7
229940034610 toothpaste Drugs 0.000 description 6
241000894006 Bacteria Species 0.000 description 5
DBMJMQXJHONAFJ-UHFFFAOYSA-M Sodium laurylsulphate Chemical compound [Na+].CCCCCCCCCCCCOS([O-])(=O)=O DBMJMQXJHONAFJ-UHFFFAOYSA-M 0.000 description 4
230000000694 effects Effects 0.000 description 4
235000019333 sodium laurylsulphate Nutrition 0.000 description 4
235000019502 Orange oil Nutrition 0.000 description 3
229910019142 PO4 Inorganic materials 0.000 description 3
239000010502 orange oil Substances 0.000 description 3
NBIIXXVUZAFLBC-UHFFFAOYSA-K phosphate Chemical compound [O-]P([O-])([O-])=O NBIIXXVUZAFLBC-UHFFFAOYSA-K 0.000 description 3
239000010452 phosphate Substances 0.000 description 3
238000003756 stirring Methods 0.000 description 3
PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 description 2
239000004141 Sodium laurylsulphate Substances 0.000 description 2
244000299461 Theobroma cacao Species 0.000 description 2
235000009470 Theobroma cacao Nutrition 0.000 description 2
230000002349 favourable effect Effects 0.000 description 2
239000000243 solution Substances 0.000 description 2
235000000346 sugar Nutrition 0.000 description 2
150000008163 sugars Chemical class 0.000 description 2
244000303040 Glycyrrhiza glabra Species 0.000 description 1
235000006200 Glycyrrhiza glabra Nutrition 0.000 description 1
235000017443 Hedysarum boreale Nutrition 0.000 description 1
235000007858 Hedysarum occidentale Nutrition 0.000 description 1
241000194019 Streptococcus mutans Species 0.000 description 1
239000013543 active substance Substances 0.000 description 1
239000002280 amphoteric surfactant Substances 0.000 description 1
230000000844 anti-bacterial effect Effects 0.000 description 1
230000001580 bacterial effect Effects 0.000 description 1
239000006071 cream Substances 0.000 description 1
238000005115 demineralization Methods 0.000 description 1
230000002328 demineralizing effect Effects 0.000 description 1
210000003298 dental enamel Anatomy 0.000 description 1
239000000551 dentifrice Substances 0.000 description 1
230000001419 dependent effect Effects 0.000 description 1
239000002552 dosage form Substances 0.000 description 1
238000007580 dry-mixing Methods 0.000 description 1
239000000284 extract Substances 0.000 description 1
235000003599 food sweetener Nutrition 0.000 description 1
150000004676 glycans Chemical class 0.000 description 1
235000011187 glycerol Nutrition 0.000 description 1
239000001947 glycyrrhiza glabra rhizome/root Substances 0.000 description 1
238000001727 in vivo Methods 0.000 description 1
230000002401 inhibitory effect Effects 0.000 description 1
150000002632 lipids Chemical class 0.000 description 1
210000004379 membrane Anatomy 0.000 description 1
239000012528 membrane Substances 0.000 description 1
230000004060 metabolic process Effects 0.000 description 1
238000000034 method Methods 0.000 description 1
210000002200 mouth mucosa Anatomy 0.000 description 1
150000007524 organic acids Chemical class 0.000 description 1
235000005985 organic acids Nutrition 0.000 description 1
229920001282 polysaccharide Polymers 0.000 description 1
239000005017 polysaccharide Substances 0.000 description 1
102000004169 proteins and genes Human genes 0.000 description 1
108090000623 proteins and genes Proteins 0.000 description 1
239000004094 surface-active agent Substances 0.000 description 1
239000003765 sweetening agent Substances 0.000 description 1
231100000331 toxic Toxicity 0.000 description 1
230000002588 toxic effect Effects 0.000 description 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/75—Rutaceae (Rue family)
- A61K36/752—Citrus, e.g. lime, orange or lemon

Landscapes

Health & Medical Sciences (AREA)
Natural Medicines & Medicinal Plants (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Engineering & Computer Science (AREA)
Alternative & Traditional Medicine (AREA)
Biotechnology (AREA)
Botany (AREA)
Medical Informatics (AREA)
Medicinal Chemistry (AREA)
Microbiology (AREA)
Mycology (AREA)
Pharmacology & Pharmacy (AREA)
Epidemiology (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Cosmetics (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicinal Preparation (AREA)

SE9704789A 1997-12-19 1997-12-19 Beredning för behandling av aphte SE511373C2 (sv)

Priority Applications (3)

Application Number	Priority Date	Filing Date	Title
SE9704789A SE511373C2 (sv)	1997-12-19	1997-12-19	Beredning för behandling av aphte
PCT/SE1998/002366 WO1999032132A1 (fr)	1997-12-19	1998-12-17	Preparation pour le traitement des aphtes
AU19911/99A AU1991199A (en)	1997-12-19	1998-12-17	A preparation for the treatment of aphtae

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
SE9704789A SE511373C2 (sv)	1997-12-19	1997-12-19	Beredning för behandling av aphte

Publications (3)

Publication Number	Publication Date
SE9704789D0 SE9704789D0 (sv)	1997-12-19
SE9704789L SE9704789L (sv)	1999-06-20
SE511373C2 true SE511373C2 (sv)	1999-09-20

Family

ID=20409495

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
SE9704789A SE511373C2 (sv)	1997-12-19	1997-12-19	Beredning för behandling av aphte

Country Status (3)

Country	Link
AU (1)	AU1991199A (fr)
SE (1)	SE511373C2 (fr)
WO (1)	WO1999032132A1 (fr)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US20120328537A1 (en) *	2011-06-23	2012-12-27	Cloonan Richard A	Topical wound management formulation

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
ZA82361B (en) *	1981-02-06	1982-12-29	Biorex Laboratories Ltd	Pharmaceutical composition for treating diseases of the oral cavity
US5531982A (en) *	1987-01-30	1996-07-02	Colgate Palmolive Company	Antimicrobial oral composition
US5229425A (en) *	1990-06-01	1993-07-20	Doyle E. Chastain	Process of producing reference bactericidal endpoint (RBE) limonene
JP3345133B2 (ja) *	1992-12-21	2002-11-18	サンスター株式会社	練歯磨組成物

1997
- 1997-12-19 SE SE9704789A patent/SE511373C2/sv unknown
1998
- 1998-12-17 WO PCT/SE1998/002366 patent/WO1999032132A1/fr not_active Ceased
- 1998-12-17 AU AU19911/99A patent/AU1991199A/en not_active Abandoned

Also Published As

Publication number	Publication date
AU1991199A (en)	1999-07-12
WO1999032132A1 (fr)	1999-07-01
SE9704789L (sv)	1999-06-20
SE9704789D0 (sv)	1997-12-19

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