SE7415247L - - Google Patents

Info

Publication number
SE7415247L
SE7415247L SE7415247A SE7415247A SE7415247L SE 7415247 L SE7415247 L SE 7415247L SE 7415247 A SE7415247 A SE 7415247A SE 7415247 A SE7415247 A SE 7415247A SE 7415247 L SE7415247 L SE 7415247L
Authority
SE
Sweden
Application number
SE7415247A
Inventor
W Mehrhof
R Pohlke
K H Becker
H-J Schliep
Original Assignee
Merck Patent Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Patent Gmbh filed Critical Merck Patent Gmbh
Publication of SE7415247L publication Critical patent/SE7415247L/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D217/00Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/22Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the nitrogen-containing ring
    • C07D217/26Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D217/00Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/12Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring
    • C07D217/14Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring other than aralkyl radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
SE7415247A 1973-12-10 1974-12-05 SE7415247L (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE2361390A DE2361390A1 (de) 1973-12-10 1973-12-10 Isochinolinderivate und verfahren zu ihrer herstellung

Publications (1)

Publication Number Publication Date
SE7415247L true SE7415247L (fr) 1975-06-11

Family

ID=5900348

Family Applications (1)

Application Number Title Priority Date Filing Date
SE7415247A SE7415247L (fr) 1973-12-10 1974-12-05

Country Status (18)

Country Link
US (1) US3985881A (fr)
JP (1) JPS5088077A (fr)
AT (1) AT351026B (fr)
BE (1) BE823027A (fr)
CA (1) CA1053675A (fr)
CH (1) CH605776A5 (fr)
CS (1) CS188933B2 (fr)
DD (1) DD115666A5 (fr)
DE (1) DE2361390A1 (fr)
DK (1) DK137007C (fr)
ES (1) ES432716A1 (fr)
FR (1) FR2253522B1 (fr)
GB (1) GB1447611A (fr)
HU (1) HU171483B (fr)
IL (1) IL46160A0 (fr)
NL (1) NL7416050A (fr)
SE (1) SE7415247L (fr)
ZA (1) ZA747820B (fr)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2504250A1 (de) * 1975-02-01 1976-08-05 Merck Patent Gmbh Tetrahydroisochinolin-derivate und verfahren zu ihrer herstellung
US4232160A (en) * 1978-10-18 1980-11-04 Miles Laboratories, Inc. Isoquinoline propionamides exhibiting analgesic properties
US4556712A (en) * 1981-05-20 1985-12-03 The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Preparation and racemization of chiral 1-benzyl-1,2,3,4-tetrahydroisoquinolines
GB8601796D0 (en) * 1986-01-24 1986-02-26 Zambeletti Spa L Compounds
DE3713743A1 (de) * 1987-04-24 1988-11-17 Boehringer Ingelheim Kg Kondensierte bis-(3,4-dihydro-l-pyridinyl)methane, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
ES2061972T3 (es) * 1988-02-19 1994-12-16 Smithkline Beecham Farma 1,2,3,4-tetrahidroisoquinoleinas, procedimiento para su preparacion y su uso como agonistas kapa-receptores.
KR890012970A (ko) * 1988-02-23 1989-09-20 추후보충 테트라히드로 이소퀴놀린 유도체
DE3827727A1 (de) * 1988-08-16 1990-02-22 Boehringer Ingelheim Kg Anellierte tetrahydropyridinessigsaeurederivate, verfahren zu deren herstellung und verwendung solcher verbindungen zur kardioprotektion
GB8827479D0 (en) * 1988-11-24 1988-12-29 Zambeletti Spa L Novel compounds
GB8916395D0 (en) * 1989-07-18 1989-09-06 Zambeletti Spa L Pharmaceuticals
US5389638A (en) * 1993-09-10 1995-02-14 Abbott Laboratories Tetrahydroisoquinolines as alpha-2 antagonists and biogenic amine uptake inhibitors
GB0225884D0 (en) * 2002-11-06 2002-12-11 Glaxo Group Ltd Novel compounds
PL2935222T3 (pl) 2012-12-21 2019-02-28 Epizyme Inc Inhibitory PRMT5 i ich zastosowania
AU2016316436B2 (en) * 2015-09-01 2021-04-29 Merck Patent Gmbh Method for the production of praziquantel and precursors thereof
CA3001857A1 (fr) * 2015-10-14 2017-04-20 Aquinnah Pharmaceuticals, Inc. Composes, compositions et methodes d'utilisation contre des granules de stress
BR112020005489A2 (pt) 2017-09-22 2020-09-24 Jubilant Epipad Llc, composto da fórmula (i), composto de fórmula (ii), composto de fórmula (iii), processo de preparação de compostos de fórmula (i), processo de preparação de compostos de fórmula (ii), processo de preparação de compostos de fórmula (iii), composição farmacêutica, método para inibir uma ou mais famílias pad em uma célula, método para tratar uma afeção mediada por um ou mais pads, utilização do composto, método para o tratamento e/ou prevenção de uma afeção mediada por um ou mais distúrbios da família pad, método para o tratamento de artrite reumatoide e método de tratamento de câncer
CN111225915B (zh) 2017-10-18 2023-03-07 朱比兰特埃皮帕德有限公司 作为pad抑制剂的咪唑并吡啶化合物
EP3707135A1 (fr) 2017-11-06 2020-09-16 Jubilant Prodel LLC Dérivés de pyrimidine utilisés en tant qu'inhibiteurs de l'activation de pd1/pd-l1
IL274762B2 (en) 2017-11-24 2023-10-01 Jubilant Episcribe Llc Novel heterocyclic compounds as prmt5 inhibitors
EP3765453A1 (fr) 2018-03-13 2021-01-20 Jubilant Prodel LLC Composés bicycliques utilisés en tant qu'inhibiteurs de l'interaction/activation de pd1/pd-l1

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2612503A (en) * 1949-04-19 1952-09-30 Smith Kline French Lab Basic ether-substituted isoquinolines
US2640829A (en) * 1950-11-10 1953-06-02 Smith Kline French Lab Isoquinolyl heterocyclic ethers
US3021331A (en) * 1959-07-20 1962-02-13 Pfizer & Co C Azabenzopyridocolines
US3483206A (en) * 1967-12-15 1969-12-09 Ciba Geigy Corp N-isoquinolylalkanoyl-n-arylamines
US3600394A (en) * 1968-05-17 1971-08-17 Searle & Co 2-aminoalkyl-3-arylisocarbostyrils

Also Published As

Publication number Publication date
US3985881A (en) 1976-10-12
DK639674A (fr) 1975-08-11
DK137007B (da) 1978-01-02
ATA981974A (de) 1978-12-15
PL93405B1 (fr) 1977-05-30
JPS5088077A (fr) 1975-07-15
AT351026B (de) 1979-07-10
ES432716A1 (es) 1977-03-01
IL46160A0 (en) 1975-02-10
CA1053675A (fr) 1979-05-01
HU171483B (hu) 1978-01-28
BE823027A (fr) 1975-06-06
FR2253522B1 (fr) 1978-06-30
CS188933B2 (en) 1979-03-30
GB1447611A (en) 1976-08-25
AU7625774A (en) 1976-06-10
DK137007C (da) 1978-06-05
DD115666A5 (fr) 1975-10-12
ZA747820B (en) 1975-12-31
NL7416050A (nl) 1975-06-12
CH605776A5 (fr) 1978-10-13
FR2253522A1 (fr) 1975-07-04
DE2361390A1 (de) 1975-06-19

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