SE7600954L - Tetrahydroisokinolinderivat och forfarande for framstellning derav - Google Patents

Tetrahydroisokinolinderivat och forfarande for framstellning derav

Info

Publication number
SE7600954L
SE7600954L SE7600954A SE7600954A SE7600954L SE 7600954 L SE7600954 L SE 7600954L SE 7600954 A SE7600954 A SE 7600954A SE 7600954 A SE7600954 A SE 7600954A SE 7600954 L SE7600954 L SE 7600954L
Authority
SE
Sweden
Prior art keywords
methyl
phenyl
carbon atoms
hal
oxo
Prior art date
Application number
SE7600954A
Other languages
English (en)
Other versions
SE433745B (sv
Inventor
J Seubert
Original Assignee
Merck Patent Ges Mit Beschrenk
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Patent Ges Mit Beschrenk filed Critical Merck Patent Ges Mit Beschrenk
Publication of SE7600954L publication Critical patent/SE7600954L/sv
Publication of SE433745B publication Critical patent/SE433745B/sv

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D217/00Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/12Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring
    • C07D217/14Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring other than aralkyl radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
SE7600954A 1975-02-01 1976-01-29 Forfarande for framstellning av tetrahydroisokinolinderivat SE433745B (sv)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19752504250 DE2504250A1 (de) 1975-02-01 1975-02-01 Tetrahydroisochinolin-derivate und verfahren zu ihrer herstellung

Publications (2)

Publication Number Publication Date
SE7600954L true SE7600954L (sv) 1976-08-02
SE433745B SE433745B (sv) 1984-06-12

Family

ID=5937889

Family Applications (1)

Application Number Title Priority Date Filing Date
SE7600954A SE433745B (sv) 1975-02-01 1976-01-29 Forfarande for framstellning av tetrahydroisokinolinderivat

Country Status (19)

Country Link
US (1) US4362875A (sv)
JP (1) JPS6113472B2 (sv)
AT (1) AT361927B (sv)
BE (1) BE838079A (sv)
CA (1) CA1085401A (sv)
CH (1) CH620680A5 (sv)
CS (1) CS188267B2 (sv)
DE (1) DE2504250A1 (sv)
DK (1) DK37376A (sv)
ES (1) ES444804A1 (sv)
FI (1) FI62832C (sv)
FR (1) FR2299032A1 (sv)
GB (1) GB1511463A (sv)
HU (1) HU171491B (sv)
IE (1) IE42945B1 (sv)
LU (1) LU74272A1 (sv)
NL (1) NL7600985A (sv)
SE (1) SE433745B (sv)
YU (1) YU24176A (sv)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2520740A1 (fr) * 1982-01-29 1983-08-05 Sanofi Sa Procede pour la preparation d'acyl-2-hexahydro-1,3,4,6,7,11b-2h-pyrazino (2,1-a) isoquinoleinones-4 et intermediaires
GB8531615D0 (en) * 1985-12-23 1986-02-05 Zambeletti Spa L Compounds
JPH01103171U (sv) * 1987-12-26 1989-07-12
EP0330360B1 (en) * 1988-02-19 1993-12-01 SmithKline Beecham Farmaceutici S.p.A. 1,2,3,4-Tetrahydroisoquinolines, processes for their preparation, and their use as kappa-receptor agonists
US5389638A (en) * 1993-09-10 1995-02-14 Abbott Laboratories Tetrahydroisoquinolines as alpha-2 antagonists and biogenic amine uptake inhibitors
CN100503582C (zh) * 2005-03-01 2009-06-24 江苏工业学院 吡喹酮合成工艺
AP2909A (en) 2009-03-17 2014-05-31 Concert Pharmaceuticals Inc Pyrazinoisoquinoline Compounds
CN102093346B (zh) * 2010-03-16 2012-09-05 浙江金伯士药业有限公司 一种吡喹酮的制备方法
WO2013067036A1 (en) * 2011-10-31 2013-05-10 Rutgers, The State University Of New Jersey Direct inhibitors of keap1-nrf2 interaction as antioxidant inflammation modulators
CN103160562B (zh) * 2013-02-28 2014-04-23 苏州同力生物医药有限公司 一种合成左旋吡喹酮的方法
AU2015349033B2 (en) * 2014-11-21 2020-01-02 Merck Patent Gmbh Method for the production of praziquantel and precursors thereof
CN107406444B (zh) * 2015-02-12 2019-07-23 浙江海正药业股份有限公司 一种吡喹酮的制备方法及其中间体化合物
CA2996813C (en) 2015-09-01 2023-09-26 Merck Patent Gmbh Method for the production of praziquantel and precursors thereof
WO2018063472A1 (en) 2016-09-27 2018-04-05 Reyoung Corporation Compositions for treating parasitic diseases and methods thereof
WO2025077920A1 (en) * 2023-10-13 2025-04-17 Tongli Biomedical Co., Ltd. Preparation method and application of a chiral amine compound and its salts

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2361390A1 (de) * 1973-12-10 1975-06-19 Merck Patent Gmbh Isochinolinderivate und verfahren zu ihrer herstellung
US4118494A (en) * 1974-08-14 1978-10-03 Hoechst Aktiengesellschaft Substituted 3,4-dihydro-2H-isoquinolin-1-thiones

Also Published As

Publication number Publication date
CS188267B2 (en) 1979-02-28
FR2299032B1 (sv) 1981-12-31
BE838079A (fr) 1976-07-30
GB1511463A (en) 1978-05-17
IE42945B1 (en) 1980-11-19
JPS51101986A (sv) 1976-09-08
JPS6113472B2 (sv) 1986-04-14
US4362875A (en) 1982-12-07
IE42945L (en) 1976-08-01
FI62832B (fi) 1982-11-30
CH620680A5 (sv) 1980-12-15
CA1085401A (en) 1980-09-09
LU74272A1 (sv) 1977-08-03
AT361927B (de) 1981-04-10
HU171491B (hu) 1978-01-28
DK37376A (da) 1976-08-02
NL7600985A (nl) 1976-08-03
SE433745B (sv) 1984-06-12
ES444804A1 (es) 1977-12-01
ATA66576A (de) 1980-09-15
YU24176A (en) 1982-05-31
FI62832C (fi) 1983-03-10
FR2299032A1 (fr) 1976-08-27
DE2504250A1 (de) 1976-08-05
FI760230A7 (sv) 1976-08-02

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