SE7705182L - Framstellning av nya bensodiazepiner - Google Patents

Framstellning av nya bensodiazepiner

Info

Publication number: SE7705182L
Authority: SE; Sweden
Prior art keywords: bensodiazepines; preparation; new; alkyl; compounds
Prior art date: 1976-05-05

Application number

SE7705182A

Other languages

English (en)

Other versions

SE432099B (sv

Inventor

H Demarne

A Hallot

Original Assignee

Clin Midy

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1976-05-05

Filing date

1977-05-04

Publication date

1977-11-06

1977-05-04 Application filed by Clin Midy filed Critical Clin Midy

1977-11-06 Publication of SE7705182L publication Critical patent/SE7705182L/sv

1984-03-19 Publication of SE432099B publication Critical patent/SE432099B/sv

Links

125000004178 (C1-C4) alkyl group Chemical group 0.000 abstract 2
125000003310 benzodiazepinyl group Chemical class N1N=C(C=CC2=C1C=CC=C2)* 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
239000003814 drug Substances 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
- C07D243/06—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
- C07D243/10—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
- C07D243/14—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
- C07D243/16—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals
- C07D243/18—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals substituted in position 2 by nitrogen, oxygen or sulfur atoms
- C07D243/24—Oxygen atoms
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Veterinary Medicine (AREA)
Life Sciences & Earth Sciences (AREA)
Neurology (AREA)
Public Health (AREA)
Bioinformatics & Cheminformatics (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Engineering & Computer Science (AREA)
Pharmacology & Pharmacy (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Biomedical Technology (AREA)
Neurosurgery (AREA)
Pain & Pain Management (AREA)
Anesthesiology (AREA)
Psychiatry (AREA)
Orthopedic Medicine & Surgery (AREA)
Physical Education & Sports Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Plural Heterocyclic Compounds (AREA)

SE7705182A 1976-05-05 1977-05-04 Forfarande for framstellning av 1,4-bensodiazepiner SE432099B (sv)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
GB18492/76A GB1538164A (en)	1976-05-05	1976-05-05	Benzodiazepine derivatives

Publications (2)

Publication Number	Publication Date
SE7705182L true SE7705182L (sv)	1977-11-06
SE432099B SE432099B (sv)	1984-03-19

Family

ID=10113358

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
SE7705182A SE432099B (sv)	1976-05-05	1977-05-04	Forfarande for framstellning av 1,4-bensodiazepiner
SE7705183A SE431543B (sv)	1976-05-05	1977-05-04	Analogiforfarande for framstellning av 1,4-bensodiazepinderivat

Family Applications After (1)

Application Number	Title	Priority Date	Filing Date
SE7705183A SE431543B (sv)	1976-05-05	1977-05-04	Analogiforfarande for framstellning av 1,4-bensodiazepinderivat

Country Status (31)

Country	Link
US (2)	US4235897A (sv)
JP (3)	JPS52156883A (sv)
AR (1)	AR219924A1 (sv)
AT (1)	AT356655B (sv)
AU (1)	AU509147B2 (sv)
BE (1)	BE854249A (sv)
CA (1)	CA1083146A (sv)
CH (2)	CH620686A5 (sv)
CS (3)	CS207399B2 (sv)
DD (1)	DD129446A5 (sv)
DE (2)	DE2719608A1 (sv)
DK (2)	DK195077A (sv)
EG (1)	EG12724A (sv)
ES (1)	ES458481A1 (sv)
FI (1)	FI771413A7 (sv)
FR (2)	FR2350345A1 (sv)
GB (1)	GB1538164A (sv)
GR (1)	GR63203B (sv)
HU (1)	HU177573B (sv)
IE (1)	IE44830B1 (sv)
IL (2)	IL51998A (sv)
MX (1)	MX4720E (sv)
NL (2)	NL7704912A (sv)
NO (2)	NO771560L (sv)
NZ (1)	NZ184012A (sv)
PH (1)	PH12641A (sv)
PT (1)	PT66500B (sv)
SE (2)	SE432099B (sv)
SU (1)	SU888820A3 (sv)
YU (1)	YU41818B (sv)
ZA (1)	ZA772628B (sv)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE2900017A1 (de) *	1978-01-10	1979-07-12	Clin Midy	3-alkoxycarbonyl-benzodiazepin- derivate, verfahren zu ihrer herstellung und sie enthaltende arzneimittel
FR2460938A1 (fr) *	1979-07-12	1981-01-30	Cm Ind	Procede d'obtention de benzodiazepines-1,4
DE3021107A1 (de) *	1980-06-04	1981-12-17	Hoechst Ag, 6000 Frankfurt	Carbamoyloxyamino-1,4-benzodiazepine, verfahren zu irer herstellung und diese enthaltende arzneimittel
JPS6038380A (ja) *	1983-08-11	1985-02-27	Shionogi & Co Ltd	１−ピペリジニル−１，４−ベンゾジアゼピン類の改良合成法
JPH04200396A (ja) *	1990-11-30	1992-07-21	Sanwa Kagaku Kenkyusho Co Ltd	過酸化水素の酵素学的高感度測定法及びそのための試薬
AU678503B2 (en) *	1993-09-24	1997-05-29	Takeda Chemical Industries Ltd.	Condensed heterocyclic compounds and their use as squalene synthetase inhibitors
KR100668045B1 (ko) *	2005-08-17	2007-01-16	한국과학기술연구원	ω-[2-(폴리알킬렌옥시)에틸티오]알킬알콕시실레인유도체와 이의 제조방법

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US28315A (en) *		1860-05-15		Improvement in method of decomposing fats into fatty acids and glycerine
US3136815A (en) *	1959-12-10	1964-06-09	Hoffmann La Roche	Amino substituted benzophenone oximes and derivatives thereof
US3236838A (en) *	1964-06-09	1966-02-22	Hoffmann La Roche	Certain 1-substituted-benzodiazepin-2-one compounds
FR1497456A (fr) *	1964-06-15	1967-10-13	Clin Byla Ets	Ortho-amino aryl cétimines, composés hétérocycliques qui s'y rattachent et prépaation de ces divers corps
USRE28315E (en)	1964-06-15	1975-01-21		Cooc.hi
US3812103A (en) *	1967-04-11	1974-05-21	Hoffmann La Roche	2,3-dihydro-1,4-benzodiazepines
CH498846A (de) *	1967-08-09	1970-11-15	Hoffmann La Roche	Verfahren zur Herstellung von Benzodiazepin-Derivaten
CH500997A (de) *	1967-08-09	1970-12-31	Hoffmann La Roche	Verfahren zur Herstellung von Benzodiazepin-Derivaten
US3657223A (en) *	1969-01-17	1972-04-18	Hoffmann La Roche	Process for the preparation of benzodiazepin-2-one derivatives
DE2008612A1 (de) *	1969-03-13	1970-10-01	F. Hoffmann-La Roche & Co Ag, Basel (Schweiz)	Benzodiazepin-Derivate
US3718646A (en) *	1970-10-05	1973-02-27	Upjohn Co	N-lower alkenyl-2,3-dihydro-2-oxo-5-phenyl-1h-1,4-benzodiazepine-1-carboxamides
IT1044223B (it) *	1972-08-09	1980-03-20	Zambeletti Spa L	I propargil 1 4 benzodiazepine

1976
- 1976-05-05 GB GB18492/76A patent/GB1538164A/en not_active Expired
1977
- 1977-03-03 AR AR267443A patent/AR219924A1/es active
- 1977-04-22 GR GR53273A patent/GR63203B/el unknown
- 1977-04-25 FR FR7712395A patent/FR2350345A1/fr active Granted
- 1977-04-25 FR FR7712394A patent/FR2350346A1/fr active Granted
- 1977-04-27 CH CH520377A patent/CH620686A5/fr not_active IP Right Cessation
- 1977-04-27 CH CH520277A patent/CH620912A5/fr not_active IP Right Cessation
- 1977-05-02 DE DE19772719608 patent/DE2719608A1/de not_active Withdrawn
- 1977-05-02 PT PT66500A patent/PT66500B/pt unknown
- 1977-05-02 MX MX775692U patent/MX4720E/es unknown
- 1977-05-02 DE DE19772719607 patent/DE2719607A1/de active Granted
- 1977-05-02 ZA ZA00772628A patent/ZA772628B/xx unknown
- 1977-05-03 IE IE889/77A patent/IE44830B1/en not_active IP Right Cessation
- 1977-05-03 IL IL51998A patent/IL51998A/xx unknown
- 1977-05-03 AU AU24813/77A patent/AU509147B2/en not_active Expired
- 1977-05-03 NO NO771560A patent/NO771560L/no unknown
- 1977-05-03 EG EG262/77A patent/EG12724A/xx active
- 1977-05-04 NL NL7704912A patent/NL7704912A/xx not_active Application Discontinuation
- 1977-05-04 DD DD7700198753A patent/DD129446A5/xx unknown
- 1977-05-04 CS CS772937A patent/CS207399B2/cs unknown
- 1977-05-04 DK DK195077A patent/DK195077A/da not_active Application Discontinuation
- 1977-05-04 FI FI771413A patent/FI771413A7/fi not_active Application Discontinuation
- 1977-05-04 BE BE177259A patent/BE854249A/xx not_active IP Right Cessation
- 1977-05-04 NZ NZ184012A patent/NZ184012A/xx unknown
- 1977-05-04 SE SE7705182A patent/SE432099B/sv not_active IP Right Cessation
- 1977-05-04 CS CS772937A patent/CS207398B2/cs unknown
- 1977-05-04 YU YU1139/77A patent/YU41818B/xx unknown
- 1977-05-04 SE SE7705183A patent/SE431543B/sv unknown
- 1977-05-04 CS CS772937A patent/CS207400B2/cs unknown
- 1977-05-04 ES ES458481A patent/ES458481A1/es not_active Expired
- 1977-05-04 DK DK195177A patent/DK195177A/da not_active Application Discontinuation
- 1977-05-04 NL NL7704911A patent/NL7704911A/xx not_active Application Discontinuation
- 1977-05-04 CA CA277,673A patent/CA1083146A/en not_active Expired
- 1977-05-05 AT AT320177A patent/AT356655B/de not_active IP Right Cessation
- 1977-05-05 HU HU77CE1132A patent/HU177573B/hu unknown
- 1977-05-05 PH PH19735A patent/PH12641A/en unknown
- 1977-05-06 JP JP5189377A patent/JPS52156883A/ja active Granted
- 1977-05-06 JP JP5189277A patent/JPS52156882A/ja active Granted
1979
- 1979-02-21 US US06/013,224 patent/US4235897A/en not_active Expired - Lifetime
- 1979-11-06 IL IL58648A patent/IL58648A0/xx unknown
1980
- 1980-01-10 SU SU802867754A patent/SU888820A3/ru active
1981
- 1981-09-11 JP JP56143702A patent/JPS5781472A/ja active Pending
- 1981-09-18 NO NO813180A patent/NO149208C/no unknown
1985
- 1985-01-28 US US06/695,557 patent/US4587245A/en not_active Expired - Fee Related

Also Published As

Publication number	Publication date
FR2350345B1 (sv)	1980-07-18
IL51998A0 (en)	1977-07-31
AU2481377A (en)	1978-11-09
EG12724A (en)	1979-12-31
NZ184012A (en)	1981-11-19
CS207399B2 (en)	1981-07-31
US4587245A (en)	1986-05-06
FR2350346B1 (sv)	1980-11-21
HU177573B (en)	1981-11-28
CS207400B2 (en)	1981-07-31
NL7704911A (nl)	1977-11-08
JPS5711317B2 (sv)	1982-03-03
CH620686A5 (sv)	1980-12-15
IL58648A0 (en)	1980-02-29
JPS6137249B2 (sv)	1986-08-22
SU888820A3 (ru)	1981-12-07
FI771413A7 (sv)	1977-11-06
NO771560L (no)	1977-11-08
FR2350345A1 (fr)	1977-12-02
NO149208C (no)	1984-03-07
IE44830L (en)	1977-11-05
DE2719608A1 (de)	1977-11-24
CS207398B2 (en)	1981-07-31
GR63203B (en)	1979-10-08
BE854249A (fr)	1977-11-04
ATA320177A (de)	1979-10-15
DK195177A (da)	1977-11-06
US4235897A (en)	1980-11-25
SE431543B (sv)	1984-02-13
CH620912A5 (sv)	1980-12-31
ES458481A1 (es)	1978-04-01
GB1538164A (en)	1979-01-10
SE432099B (sv)	1984-03-19
JPS5781472A (en)	1982-05-21
PH12641A (en)	1979-07-11
NO149208B (no)	1983-11-28
NL7704912A (nl)	1977-11-08
DE2719607A1 (de)	1977-11-17
AR219924A1 (es)	1980-09-30
IL51998A (en)	1981-05-20
DD129446A5 (de)	1978-01-18
ZA772628B (en)	1978-03-29
DK195077A (da)	1977-11-06
YU113977A (en)	1982-08-31
AU509147B2 (en)	1980-04-24
YU41818B (en)	1988-02-29
AT356655B (de)	1980-05-12
MX4720E (es)	1982-08-13
FR2350346A1 (fr)	1977-12-02
SE7705183L (sv)	1977-11-06
PT66500B (fr)	1978-10-13
JPS52156882A (en)	1977-12-27
PT66500A (fr)	1977-06-01
CA1083146A (en)	1980-08-05
JPS52156883A (en)	1977-12-27
IE44830B1 (en)	1982-04-07
NO813180L (no)	1977-11-08
DE2719607C2 (sv)	1987-07-16

Legal Events

Date

Code

Title

Description

1995-01-31

NUG

Patent has lapsed

Ref document number: 7705182-9

Effective date: 19880318

Format of ref document f/p: F

Publication	Publication Date	Title
FI73969B (fi)	1987-08-31	Foerfarande foer framstaellning av terapeutiskt aktiva trans-4-aminometylcyklohexankarboxylsyraderivat.
JPS5297950A (en)	1977-08-17	Chalconeether derivatives
SE7705182L (sv)	1977-11-06	Framstellning av nya bensodiazepiner
ZA827922B (en)	1983-09-28	Pyridazinone derivatives, their preparation and their use as fungicides
GB2104890B (en)	1985-08-07	Pyridinecarbinols, their preparation and fungicides containing them
ES458557A1 (es)	1978-04-01	Un procedimiento de preparacion de derivados de quinazolina.
SE7910072L (sv)	1980-06-08	Pyrrolo- eller pyrido(2,1-c)(1,4)tiaziner eller -tiazepiner
SE433081B (sv)	1984-05-07	Forfarande for framstellning av cefalosporinforeningar
SE8001556L (sv)	1980-09-03	Tetrahydrobensotiazolylimidazolidinoner
JPS5545677A (en)	1980-03-31	455methanoobufadienolideerhamnosideits manufacture and medicine containing it
JPS52116495A (en)	1977-09-29	Novel naphthyridine derivatives
FR2354708A1 (fr)	1978-01-13	3-phenyl-5-(methyl substitue) isoxazoles en tant que fongicides
SE7505272L (sv)	1975-11-10	Nya, kvevehaltiga, polycykliska foreningar jemte sett for deras framstellning.
JPS5293770A (en)	1977-08-06	Benzotriazoles
SE8302824L (sv)	1983-11-21	Nya herbicidforeningar
SE7508075L (sv)	1976-01-19	Forfarande for framstellning av nya di-(substituerad alkyl)-aminoforeningar.
DK287580A (da)	1981-01-05	Fremgangsmaade til fremstilling af uorganiske forbindelser af cyclophosphazen-typen
JPS5265299A (en)	1977-05-30	Synthesis of 2-substituted-thioadenosine-n-oxides
JPS53127443A (en)	1978-11-07	Organosilicon compounds
NO791224L (no)	1980-03-03	Fremgangsmaate for fremstilling av heterocykliske forbindelser
JPS5359664A (en)	1978-05-29	Novel imidazole derivatives
JPS5210218A (en)	1977-01-26	Preparation of beta-sulfenylacrylamides
JPS5353652A (en)	1978-05-16	Novel imidazole derivatives
IL64067A0 (en)	1982-01-31	2-(n-aryl,n-1,2,3-thiazolylcarbonyl)-aminobutyrolactones,their preparation and their use as fungicides
FR2432199A1 (fr)	1980-02-22	Nouveaux dielectriques liquides