SE7706567L - Biologiskt aktiva peptider - Google Patents

Biologiskt aktiva peptider

Info

Publication number: SE7706567L
Authority: SE; Sweden
Prior art keywords: image; peptides; prepared; peptide; formula iii
Prior art date: 1976-06-07

Application number

SE7706567A

Other languages

Unknown language ( )

English (en)

Other versions

SE441452B (sv

Inventor

W W Vale

J E F Rivier

M R Brown

Original Assignee

Salk Inst For Biological Studi

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1976-06-07

Filing date

1977-06-06

Publication date

1977-12-08

1977-04-07 Priority claimed from US05/785,533 external-priority patent/US4133782A/en

1977-06-06 Application filed by Salk Inst For Biological Studi filed Critical Salk Inst For Biological Studi

1977-12-08 Publication of SE7706567L publication Critical patent/SE7706567L/sv

1985-10-07 Publication of SE441452B publication Critical patent/SE441452B/sv

Links

108090000765 processed proteins & peptides Proteins 0.000 title abstract 6
102000004196 processed proteins & peptides Human genes 0.000 title abstract 4
150000001875 compounds Chemical class 0.000 abstract 2
NOESYZHRGYRDHS-UHFFFAOYSA-N insulin Chemical compound N1C(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(NC(=O)CN)C(C)CC)CSSCC(C(NC(CO)C(=O)NC(CC(C)C)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CCC(N)=O)C(=O)NC(CC(C)C)C(=O)NC(CCC(O)=O)C(=O)NC(CC(N)=O)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CSSCC(NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2C=CC(O)=CC=2)NC(=O)C(CC(C)C)NC(=O)C(C)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2NC=NC=2)NC(=O)C(CO)NC(=O)CNC2=O)C(=O)NCC(=O)NC(CCC(O)=O)C(=O)NC(CCCNC(N)=N)C(=O)NCC(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC(O)=CC=3)C(=O)NC(C(C)O)C(=O)N3C(CCC3)C(=O)NC(CCCCN)C(=O)NC(C)C(O)=O)C(=O)NC(CC(N)=O)C(O)=O)=O)NC(=O)C(C(C)CC)NC(=O)C(CO)NC(=O)C(C(C)O)NC(=O)C1CSSCC2NC(=O)C(CC(C)C)NC(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CC(N)=O)NC(=O)C(NC(=O)C(N)CC=1C=CC=CC=1)C(C)C)CC1=CN=CN1 NOESYZHRGYRDHS-UHFFFAOYSA-N 0.000 abstract 2
231100000252 nontoxic Toxicity 0.000 abstract 2
230000003000 nontoxic effect Effects 0.000 abstract 2
125000006239 protecting group Chemical group 0.000 abstract 2
239000011347 resin Substances 0.000 abstract 2
229920005989 resin Polymers 0.000 abstract 2
150000003839 salts Chemical class 0.000 abstract 2
102400000321 Glucagon Human genes 0.000 abstract 1
108060003199 Glucagon Proteins 0.000 abstract 1
102000004877 Insulin Human genes 0.000 abstract 1
108090001061 Insulin Proteins 0.000 abstract 1
150000001413 amino acids Chemical class 0.000 abstract 1
206010012601 diabetes mellitus Diseases 0.000 abstract 1
230000000694 effects Effects 0.000 abstract 1
MASNOZXLGMXCHN-ZLPAWPGGSA-N glucagon Chemical compound C([C@@H](C(=O)N[C@H](C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC=1C2=CC=CC=C2NC=1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H]([C@@H](C)O)C(O)=O)C(C)C)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CO)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC=1C=CC(O)=CC=1)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CO)NC(=O)[C@H](CC=1C=CC(O)=CC=1)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](CC=1C=CC=CC=1)NC(=O)[C@@H](NC(=O)CNC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CO)NC(=O)[C@@H](N)CC=1NC=NC=1)[C@@H](C)O)[C@@H](C)O)C1=CC=CC=C1 MASNOZXLGMXCHN-ZLPAWPGGSA-N 0.000 abstract 1
229960004666 glucagon Drugs 0.000 abstract 1
229940125396 insulin Drugs 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/655—Somatostatins
- C07K14/6555—Somatostatins at least 1 amino acid in D-form
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Organic Chemistry (AREA)
Medicinal Chemistry (AREA)
General Health & Medical Sciences (AREA)
Endocrinology (AREA)
Chemical Kinetics & Catalysis (AREA)
Veterinary Medicine (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Diabetes (AREA)
Pharmacology & Pharmacy (AREA)
Bioinformatics & Cheminformatics (AREA)
Animal Behavior & Ethology (AREA)
Engineering & Computer Science (AREA)
Public Health (AREA)
General Chemical & Material Sciences (AREA)
Toxicology (AREA)
Zoology (AREA)
Gastroenterology & Hepatology (AREA)
Biochemistry (AREA)
Biophysics (AREA)
Genetics & Genomics (AREA)
Molecular Biology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Peptides Or Proteins (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

SE7706567A 1976-06-07 1977-06-06 Forfarande for framstellning av somatostatinanaloger SE441452B (sv)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US69328276A	1976-06-07	1976-06-07
US05/785,533 US4133782A (en)	1976-06-07	1977-04-07	Somatostatin analogs with dissociated biological activities

Publications (2)

Publication Number	Publication Date
SE7706567L true SE7706567L (sv)	1977-12-08
SE441452B SE441452B (sv)	1985-10-07

Family

ID=27105142

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
SE7706567A SE441452B (sv)	1976-06-07	1977-06-06	Forfarande for framstellning av somatostatinanaloger

Country Status (11)

Country	Link
JP (1)	JPS52156885A (sv)
AU (1)	AU509631B2 (sv)
CA (1)	CA1102313A (sv)
CH (1)	CH640827A5 (sv)
DE (1)	DE2725735A1 (sv)
DK (1)	DK250977A (sv)
FR (1)	FR2375190A1 (sv)
GB (1)	GB1567341A (sv)
IL (1)	IL52231A (sv)
NL (1)	NL7706002A (sv)
SE (1)	SE441452B (sv)

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3904594A (en) *	1973-07-02	1975-09-09	Salk Inst For Biological Studi	Somatostatin and acylated des-(ala' 1', gly' 2') derivatives thereof
US3842067A (en) *	1973-07-27	1974-10-15	American Home Prod	Synthesis of(des-asn5)-srif and intermediates

1977
- 1977-06-01 NL NL7706002A patent/NL7706002A/xx not_active Application Discontinuation
- 1977-06-02 AU AU25775/77A patent/AU509631B2/en not_active Expired
- 1977-06-02 IL IL52231A patent/IL52231A/xx unknown
- 1977-06-03 GB GB23695/77A patent/GB1567341A/en not_active Expired
- 1977-06-06 CA CA279,918A patent/CA1102313A/en not_active Expired
- 1977-06-06 FR FR7717188A patent/FR2375190A1/fr active Granted
- 1977-06-06 SE SE7706567A patent/SE441452B/sv not_active IP Right Cessation
- 1977-06-06 JP JP6657677A patent/JPS52156885A/ja active Granted
- 1977-06-07 DE DE19772725735 patent/DE2725735A1/de not_active Withdrawn
- 1977-06-07 DK DK250977A patent/DK250977A/da not_active Application Discontinuation
- 1977-06-07 CH CH702277A patent/CH640827A5/de not_active IP Right Cessation

Also Published As

Publication number	Publication date
NL7706002A (nl)	1977-12-09
CH640827A5 (en)	1984-01-31
GB1567341A (en)	1980-05-14
JPS52156885A (en)	1977-12-27
SE441452B (sv)	1985-10-07
AU509631B2 (en)	1980-05-22
DK250977A (da)	1977-12-08
AU2577577A (en)	1978-12-07
CA1102313A (en)	1981-06-02
IL52231A (en)	1980-05-30
FR2375190A1 (fr)	1978-07-21
FR2375190B1 (sv)	1981-10-30
IL52231A0 (en)	1977-08-31
DE2725735A1 (de)	1977-12-15
JPS6315280B2 (sv)	1988-04-04

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Legal Events

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1995-01-31

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