SE7714614L - Sett att framstella nya 11beta-substituerade 1,3,5(10)-triensteroidderivat - Google Patents
Sett att framstella nya 11beta-substituerade 1,3,5(10)-triensteroidderivatInfo
- Publication number
- SE7714614L SE7714614L SE7714614A SE7714614A SE7714614L SE 7714614 L SE7714614 L SE 7714614L SE 7714614 A SE7714614 A SE 7714614A SE 7714614 A SE7714614 A SE 7714614A SE 7714614 L SE7714614 L SE 7714614L
- Authority
- SE
- Sweden
- Prior art keywords
- carbon atoms
- hydrogen
- group
- alkyl
- substituted
- Prior art date
Links
- 125000004432 carbon atom Chemical group C* 0.000 abstract 11
- 229910052739 hydrogen Inorganic materials 0.000 abstract 5
- 239000001257 hydrogen Substances 0.000 abstract 5
- 125000004435 hydrogen atom Chemical class [H]* 0.000 abstract 5
- 125000000217 alkyl group Chemical group 0.000 abstract 3
- 150000001732 carboxylic acid derivatives Chemical class 0.000 abstract 3
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 3
- 125000004423 acyloxy group Chemical group 0.000 abstract 2
- 125000003710 aryl alkyl group Chemical group 0.000 abstract 2
- HLCRYAZDZCJZFG-BDXSIMOUSA-N (8s,9s,13s,14s)-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthrene Chemical class C1CC2=CC=CC=C2[C@@H]2[C@@H]1[C@@H]1CCC[C@@]1(C)CC2 HLCRYAZDZCJZFG-BDXSIMOUSA-N 0.000 abstract 1
- 125000003903 2-propenyl group Chemical group [H]C([*])([H])C([H])=C([H])[H] 0.000 abstract 1
- NINIDFKCEFEMDL-UHFFFAOYSA-N Sulfur Chemical compound [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 abstract 1
- 125000002252 acyl group Chemical group 0.000 abstract 1
- 125000003342 alkenyl group Chemical group 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 125000000304 alkynyl group Chemical group 0.000 abstract 1
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical group [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 abstract 1
- 230000001076 estrogenic effect Effects 0.000 abstract 1
- 125000000623 heterocyclic group Chemical group 0.000 abstract 1
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 1
- 125000003107 substituted aryl group Chemical group 0.000 abstract 1
- 229910052717 sulfur Inorganic materials 0.000 abstract 1
- 239000011593 sulfur Substances 0.000 abstract 1
- 125000004417 unsaturated alkyl group Chemical group 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J51/00—Normal steroids with unmodified cyclopenta(a)hydrophenanthrene skeleton not provided for in groups C07J1/00 - C07J43/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
- C07J1/0051—Estrane derivatives
- C07J1/0081—Substituted in position 17 alfa and 17 beta
- C07J1/0088—Substituted in position 17 alfa and 17 beta the substituent in position 17 alfa being an unsaturated hydrocarbon group
- C07J1/0096—Alkynyl derivatives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J21/00—Normal steroids containing carbon, hydrogen, halogen or oxygen having an oxygen-containing hetero ring spiro-condensed with the cyclopenta(a)hydrophenanthrene skeleton
- C07J21/005—Ketals
- C07J21/006—Ketals at position 3
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J33/00—Normal steroids having a sulfur-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton
- C07J33/002—Normal steroids having a sulfur-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton not condensed
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J7/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms
- C07J7/0005—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21
- C07J7/001—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by a keto group
- C07J7/004—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by a keto group substituted in position 17 alfa
- C07J7/0045—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by a keto group substituted in position 17 alfa not substituted in position 16
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
- C07J71/0005—Oxygen-containing hetero ring
- C07J71/001—Oxiranes
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Steroid Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR7700859A FR2377419A1 (fr) | 1977-01-13 | 1977-01-13 | Nouveaux derives steroides 11b-substitues 1,3,5 (10) trieniques, leur procede de preparation et leur application comme medicament |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| SE7714614L true SE7714614L (sv) | 1978-07-14 |
| SE435516B SE435516B (sv) | 1984-10-01 |
Family
ID=9185438
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SE7714614A SE435516B (sv) | 1977-01-13 | 1977-12-21 | Sett att framstella nya 11beta-substituerade 1,3,5(10)-triensteroidderivat |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US4272530A (sv) |
| JP (1) | JPS5390254A (sv) |
| BE (1) | BE862870A (sv) |
| CA (1) | CA1121339A (sv) |
| CH (1) | CH630646A5 (sv) |
| DE (1) | DE2801417A1 (sv) |
| DK (1) | DK161334C (sv) |
| FR (1) | FR2377419A1 (sv) |
| GB (1) | GB1595133A (sv) |
| HU (1) | HU176154B (sv) |
| IE (1) | IE46302B1 (sv) |
| LU (1) | LU78859A1 (sv) |
| NL (1) | NL7800364A (sv) |
| SE (1) | SE435516B (sv) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NL7701384A (nl) * | 1977-02-10 | 1978-08-14 | Akzo Nv | Werkwijze voor het bereiden van nieuwe steroiden van de oestraanreeks. |
| FR2528434B1 (fr) * | 1982-06-11 | 1985-07-19 | Roussel Uclaf | Nouveaux 19-nor steroides substitues en 11b et eventuellement en 2, leur procede de preparation et leur application comme medicament |
| FR2522328B1 (fr) * | 1982-03-01 | 1986-02-14 | Roussel Uclaf | Nouveaux produits derives de la structure 3-ceto 4,9 19-nor steroides, leur procede de preparation et leur application comme medicaments |
| FR2640977A2 (en) * | 1982-06-11 | 1990-06-29 | Roussel Uclaf | New position-11 substituted 19-norsteroids and their application as medicinal products. |
| DE3625315A1 (de) * | 1986-07-25 | 1988-01-28 | Schering Ag | 11ss-(4-isopropenylphenyl)-estra-4,9-diene, deren herstellung und diese enthaltende pharmazeutische praeparate |
| DE3925179C2 (de) * | 1988-08-22 | 1996-07-18 | Volkswagen Ag | Ansaugluftsteuersystem zum Betreiben einer Brennkraftmaschine mit Leerlaufdrehzahlregelung |
| DE4018168A1 (de) * | 1990-06-01 | 1991-12-05 | Schering Ag | Ausgangsverbindungen fuer die herstellung von 10ss-h-steroiden und ein verfahren zur herstellung dieser ausgangsverbindungen |
| DE4132182A1 (de) * | 1991-09-24 | 1993-03-25 | Schering Ag | 11(beta)-substituierte 14, 17-ethanoestratriene, verfahren zur herstellung dieser verbindungen, sowie ihre verwendung zur herstellung von arzneimitteln |
| US5427766A (en) * | 1993-11-15 | 1995-06-27 | The Dow Chemical Company | Radiolabeled steroids for use in radiochemical-guided surgery |
| AU8201601A (en) | 2000-07-28 | 2002-02-13 | Akzo Nobel Nv | 16alpha-methyl or ethyl substituted estrogens |
| FR2826004B1 (fr) | 2001-06-13 | 2008-03-28 | Aventis Pharma Sa | Procede de preparation de derives estrogenes |
| DK1624878T3 (da) * | 2003-05-22 | 2007-01-08 | Pantarhei Bioscience Bv | Anvendelse af præparater som omfatter en östrogen komponent til behandling og forebyggelse af muskel-skelet-smerte |
| UA89964C2 (ru) | 2004-09-08 | 2010-03-25 | Н.В. Органон | 15β-ЗАМЕЩЕННЫЕ СТЕРОИДЫ, КОТОРЫЕ ИМЕЮТ СЕЛЕКТИВНУЮ ЭСТРОГЕННУЮ АКТИВНОСТЬ |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3337365A (en) * | 1963-03-25 | 1967-08-22 | Ibm | Electrical resistance composition and method of using the same to form a resistor |
| US3299108A (en) * | 1965-10-18 | 1967-01-17 | Searle & Co | 17alpha-alkynyl/alkenyl-13beta-alkyl-11-alkylgona-1, 3, 5 (10)-triene-3, 17beta-diols, ethers and esters thereof and intermediates thereto |
| US3346602A (en) * | 1966-10-12 | 1967-10-10 | Searle & Co | 13beta-alkyl-11-alkylgona-1, 3, 5 (10)-trien-17-ones, ethers and esters thereof |
| US3465010A (en) * | 1966-11-22 | 1969-09-02 | Searle & Co | 17 - (unsaturated hydrocarbon - substituted) 11,13beta - dialkylgon -4 - ene - 3,17beta-diols and esters thereof |
| US3629304A (en) * | 1969-06-16 | 1971-12-21 | Searle & Co | 17alpha-alkynyl - 11beta 13beta - dialkylgona-1 3 5 (10)-triene - 3 17beta-diol 3-cycloalkyl ethers compositions and method |
| GB1255345A (en) * | 1969-08-15 | 1971-12-01 | Searle & Co | 3-(3-OXO-11beta13beta-DIALKYL-17beta-HYDROXYGON-4-EN-17alpha-YL) PROPIONIC ACID gamma-LACTONE |
| US3755301A (en) * | 1972-06-23 | 1973-08-28 | Searle & Co | Manufacture of 11-alkyl steroids |
| FI54128C (fi) * | 1972-12-09 | 1978-10-10 | Akzo Nv | Foerfarande foer framstaellning av nya 11,11-alkylidensteroider ur oestran- och 19-norpregnanserien med foerbaettrad hormonell verkan |
| FR2235949B1 (sv) * | 1973-06-18 | 1978-03-17 | Roussel Uclaf | |
| NL7317358A (nl) * | 1973-12-19 | 1975-06-23 | Akzo Nv | Nieuwe 11(beta)-alkylsteroiden van de oestraanreeks. |
-
1977
- 1977-01-13 FR FR7700859A patent/FR2377419A1/fr active Granted
- 1977-12-21 SE SE7714614A patent/SE435516B/sv not_active IP Right Cessation
-
1978
- 1978-01-06 US US05/867,486 patent/US4272530A/en not_active Expired - Lifetime
- 1978-01-12 HU HU78RO955A patent/HU176154B/hu unknown
- 1978-01-12 LU LU78859A patent/LU78859A1/xx unknown
- 1978-01-12 DK DK013978A patent/DK161334C/da not_active IP Right Cessation
- 1978-01-12 NL NL7800364A patent/NL7800364A/xx not_active Application Discontinuation
- 1978-01-12 CA CA000294815A patent/CA1121339A/fr not_active Expired
- 1978-01-12 BE BE184285A patent/BE862870A/xx not_active IP Right Cessation
- 1978-01-13 JP JP206778A patent/JPS5390254A/ja active Granted
- 1978-01-13 IE IE79/78A patent/IE46302B1/en not_active IP Right Cessation
- 1978-01-13 GB GB1377/78A patent/GB1595133A/en not_active Expired
- 1978-01-13 DE DE19782801417 patent/DE2801417A1/de active Granted
- 1978-01-13 CH CH39178A patent/CH630646A5/fr not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| IE46302B1 (en) | 1983-04-20 |
| DK161334B (da) | 1991-06-24 |
| DK13978A (da) | 1978-07-14 |
| LU78859A1 (fr) | 1978-09-18 |
| FR2377419B1 (sv) | 1979-04-20 |
| DK161334C (da) | 1991-12-09 |
| CH630646A5 (fr) | 1982-06-30 |
| NL7800364A (nl) | 1978-07-17 |
| GB1595133A (en) | 1981-08-05 |
| BE862870A (fr) | 1978-07-12 |
| HU176154B (en) | 1980-12-28 |
| DE2801417A1 (de) | 1978-07-20 |
| SE435516B (sv) | 1984-10-01 |
| IE780079L (en) | 1978-07-13 |
| US4272530A (en) | 1981-06-09 |
| CA1121339A (fr) | 1982-04-06 |
| FR2377419A1 (fr) | 1978-08-11 |
| JPS6257638B2 (sv) | 1987-12-02 |
| DE2801417C2 (sv) | 1992-09-17 |
| JPS5390254A (en) | 1978-08-08 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| NAL | Patent in force |
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| NUG | Patent has lapsed |
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