SE7901276L - Aminosockerderivat - Google Patents

Aminosockerderivat

Info

Publication number: SE7901276L
Authority: SE; Sweden
Prior art keywords: sugar derivatives; amino sugar; trestatin; inhibition; compositions
Prior art date: 1978-02-14

Application number

SE7901276A

Other languages

Unknown language ( )

English (en)

Swedish (sv)

Inventor

Y Suhara

K Ogawa

K Yokose

K Watanabe

Original Assignee

Hoffmann La Roche

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1978-02-14

Filing date

1979-02-13

Publication date

1979-08-15

1979-02-13 Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche

1979-08-15 Publication of SE7901276L publication Critical patent/SE7901276L/

Links

150000002336 glycosamine derivatives Chemical class 0.000 title 1
239000000203 mixture Substances 0.000 abstract 3
WEDWQCPYKKZMDF-UHFFFAOYSA-N 2-[5-[5-[5-[3,4-dihydroxy-6-methyl-5-[[4,5,6-trihydroxy-3-(hydroxymethyl)cyclohex-2-en-1-yl]amino]oxan-2-yl]oxy-3,4-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-3,4-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-3,4-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-6-(hydro Chemical compound OC1C(O)C(NC2C(C(O)C(O)C(CO)=C2)O)C(C)OC1OC(C(C1O)O)C(CO)OC1OC(C(C1O)O)C(CO)OC1OC(C(C1O)O)C(CO)OC1OC1OC(CO)C(O)C(O)C1O WEDWQCPYKKZMDF-UHFFFAOYSA-N 0.000 abstract 2
229930186167 Trestatin Natural products 0.000 abstract 2
230000005764 inhibitory process Effects 0.000 abstract 2
150000003839 salts Chemical class 0.000 abstract 2
PYVAAPGPTLLDGV-AGKSRYJLSA-N (2r,3r,4s,5s,6r)-2-[(2r,3r,4r,5s,6r)-5-[(2r,3r,4r,5s,6r)-5-[(2r,3r,4r,5s,6r)-5-[(2r,3r,4s,5s,6r)-5-[[(1s,4r,5r,6s)-4-[(2s,3r,4r,5s,6r)-5-[(2r,3r,4s,5s,6r)-3,4-dihydroxy-6-methyl-5-[[(1s,4r,5s,6s)-4,5,6-trihydroxy-3-(hydroxymethyl)cyclohex-2-en-1-yl]amino] Chemical compound O([C@H]1O[C@H](CO)[C@H]([C@@H]([C@H]1O)O)O[C@H]1O[C@H](CO)[C@H]([C@@H]([C@H]1O)O)O[C@H]1O[C@H](CO)[C@H]([C@@H]([C@H]1O)O)O[C@H]1O[C@H](C)[C@H]([C@@H]([C@H]1O)O)N[C@@H]1[C@H](O)[C@@H](O)[C@@H](C(=C1)CO)O[C@H]1O[C@H](CO)[C@H]([C@@H]([C@H]1O)O)O[C@H]1O[C@@H]([C@H]([C@H](O)[C@H]1O)N[C@@H]1[C@@H]([C@@H](O)[C@H](O)C(CO)=C1)O)C)[C@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O PYVAAPGPTLLDGV-AGKSRYJLSA-N 0.000 abstract 1
101710184309 Probable sucrose-6-phosphate hydrolase Proteins 0.000 abstract 1
102400000472 Sucrase Human genes 0.000 abstract 1
101710112652 Sucrose-6-phosphate hydrolase Proteins 0.000 abstract 1
PYVAAPGPTLLDGV-UHFFFAOYSA-N Trestatin A Natural products OC1C(O)C(NC2C(C(O)C(O)C(CO)=C2)O)C(C)OC1OC(C(C1O)O)C(CO)OC1OC(C(=C1)CO)C(O)C(O)C1NC(C(C1O)O)C(C)OC1OC(C(C1O)O)C(CO)OC1OC(C(C1O)O)C(CO)OC1OC(C(C1O)O)C(CO)OC1OC1OC(CO)C(O)C(O)C1O PYVAAPGPTLLDGV-UHFFFAOYSA-N 0.000 abstract 1
102000004139 alpha-Amylases Human genes 0.000 abstract 1
108090000637 alpha-Amylases Proteins 0.000 abstract 1
229940024171 alpha-amylase Drugs 0.000 abstract 1
235000011073 invertase Nutrition 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/20—Carbocyclic rings
- C07H15/22—Cyclohexane rings, substituted by nitrogen atoms
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/99—Enzyme inactivation by chemical treatment
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P19/00—Preparation of compounds containing saccharide radicals
- C12P19/26—Preparation of nitrogen-containing carbohydrates

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Genetics & Genomics (AREA)
Zoology (AREA)
Wood Science & Technology (AREA)
Biotechnology (AREA)
General Health & Medical Sciences (AREA)
Molecular Biology (AREA)
Biochemistry (AREA)
Bioinformatics & Cheminformatics (AREA)
Microbiology (AREA)
General Chemical & Material Sciences (AREA)
General Engineering & Computer Science (AREA)
Chemical Kinetics & Catalysis (AREA)
Medicinal Chemistry (AREA)
Biomedical Technology (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Saccharide Compounds (AREA)
Peptides Or Proteins (AREA)
Enzymes And Modification Thereof (AREA)
Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

SE7901276A 1978-02-14 1979-02-13 Aminosockerderivat SE7901276L (sv)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
GB583478		1978-02-14

Publications (1)

Publication Number	Publication Date
SE7901276L true SE7901276L (sv)	1979-08-15

Family

ID=9803510

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
SE7901276A SE7901276L (sv)	1978-02-14	1979-02-13	Aminosockerderivat

Country Status (26)

Country	Link
US (1)	US4273765A (lt)
EP (1)	EP0003616B1 (lt)
JP (1)	JPS54163511A (lt)
AR (1)	AR219150A1 (lt)
AT (1)	AT367451B (lt)
AU (1)	AU527318B2 (lt)
CA (1)	CA1121290A (lt)
DE (2)	DE2905649A1 (lt)
DK (1)	DK149599C (lt)
ES (1)	ES477653A1 (lt)
FI (1)	FI63062C (lt)
FR (1)	FR2416901A1 (lt)
GR (1)	GR72817B (lt)
HU (1)	HU181442B (lt)
IE (1)	IE47916B1 (lt)
IL (1)	IL56626A0 (lt)
LU (1)	LU80906A1 (lt)
MC (1)	MC1253A1 (lt)
NL (1)	NL7901182A (lt)
NO (1)	NO153011C (lt)
NZ (1)	NZ189625A (lt)
PH (1)	PH15084A (lt)
PT (1)	PT69218A (lt)
SE (1)	SE7901276L (lt)
YU (1)	YU41437B (lt)
ZA (1)	ZA79528B (lt)

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DE3166093D1 (en) *	1981-01-05	1984-10-18	Takeda Chemical Industries Ltd	N-substituted pseudo-aminosugars, their production and use
JPS57146713A (en) *	1981-03-09	1982-09-10	Akira Endo	Hypoglycemic
US4595678A (en) *	1982-03-19	1986-06-17	Takeda Chemical Industries, Ltd.	N-substituted pseudo-aminosugars and pharmaceutical compositions containing same
US4678812A (en) *	1986-05-30	1987-07-07	E. I. Du Pont De Nemours And Company	Trehalose as stabilizer and tableting excipient
US4762857A (en) *	1986-05-30	1988-08-09	E. I. Du Pont De Nemours And Company	Trehalose as stabilizer and tableting excipient
US4885361A (en) *	1987-07-31	1989-12-05	Hoffmann-La Roche Inc.	Sulfated oligosaccharides
AU667462B2 (en) *	1990-11-30	1996-03-28	Monoclonetics International Incorporated	Methods for the diagnosis of chronic lower back and cervical pain
CA2128044C (en) *	1993-08-05	2007-02-20	Klaus-Dieter Bremer	Pharmaceutical compositions comprising a glucosidase and/or amylase inhibitor, and a lipase inhibitor
ES2272418T3 (es) *	2000-05-24	2007-05-01	Pfizer Inc.	Tratamiento de acidos del rumen con inhibidores de alfa-amilasa.
US7022684B2 (en) *	2000-05-24	2006-04-04	Pfizer Inc.	Treatment of rumen acidosis with α-amylase inhibitors
CN1882327A (zh)	2003-11-19	2006-12-20	症变治疗公司	含磷的新的拟甲状腺素药
US7262318B2 (en) *	2004-03-10	2007-08-28	Pfizer, Inc.	Substituted heteroaryl- and phenylsulfamoyl compounds
US20050288340A1 (en) *	2004-06-29	2005-12-29	Pfizer Inc	Substituted heteroaryl- and phenylsulfamoyl compounds
WO2006056845A1 (en) *	2004-11-23	2006-06-01	Warner-Lambert Company Llc	7-(2h-pyrazol-3-yl)-3, 5-dihyroxy-heptanoic acid derivatives as hmg co-a reductase inhibitors for the treatment of lipidemia
US7741317B2 (en)	2005-10-21	2010-06-22	Bristol-Myers Squibb Company	LXR modulators
US7888376B2 (en)	2005-11-23	2011-02-15	Bristol-Myers Squibb Company	Heterocyclic CETP inhibitors
CN101663262B (zh)	2006-12-01	2014-03-26	百时美施贵宝公司	用于治疗动脉粥样硬化和心血管疾病的作为cetp抑制剂的n-(3-苄基)-2,2-(二苯基)-丙-1胺衍生物
EP2527360B1 (en)	2007-06-04	2015-10-28	Synergy Pharmaceuticals Inc.	Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders
US8969514B2 (en)	2007-06-04	2015-03-03	Synergy Pharmaceuticals, Inc.	Agonists of guanylate cyclase useful for the treatment of hypercholesterolemia, atherosclerosis, coronary heart disease, gallstone, obesity and other cardiovascular diseases
KR20100130993A (ko) *	2008-04-11	2010-12-14	아스텔라스세이야쿠 가부시키가이샤	아미노당 화합물 및 그의 생산 방법
EP2810951B1 (en)	2008-06-04	2017-03-15	Synergy Pharmaceuticals Inc.	Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders
EP3241839B1 (en)	2008-07-16	2019-09-04	Bausch Health Ireland Limited	Agonists of guanylate cyclase useful for the treatment of gastrointestinal, inflammation, cancer and other disorders
US20120046364A1 (en)	2009-02-10	2012-02-23	Metabasis Therapeutics, Inc.	Novel Sulfonic Acid-Containing Thyromimetics, and Methods for Their Use
WO2011145022A1 (en)	2010-05-21	2011-11-24	Pfizer Inc.	2-phenyl benzoylamides
US20130156720A1 (en)	2010-08-27	2013-06-20	Ironwood Pharmaceuticals, Inc.	Compositions and methods for treating or preventing metabolic syndrome and related diseases and disorders
US9616097B2 (en)	2010-09-15	2017-04-11	Synergy Pharmaceuticals, Inc.	Formulations of guanylate cyclase C agonists and methods of use
JP2014513923A (ja)	2011-03-04	2014-06-19	ファイザー・インク	Ｅｄｎ３様ペプチドおよびその使用
US20150050371A1 (en)	2012-03-09	2015-02-19	Biotropics Malaysia Berhad	Extract Formulations of Rhodamnia Cinerea And Uses Thereof
CA2905435A1 (en)	2013-03-15	2014-09-25	Synergy Pharmaceuticals Inc.	Compositions useful for the treatment of gastrointestinal disorders
CA2905438A1 (en)	2013-03-15	2014-09-25	Synergy Pharmaceuticals Inc.	Agonists of guanylate cyclase and their uses
MX2015014666A (es)	2013-04-17	2016-03-01	Pfizer	Derivados de n-piperidin-3-ilbenzamida para tratar enfermedades cardiovasculares.
SI3004138T1 (sl)	2013-06-05	2024-07-31	Bausch Health Ireland Limited	Ultra čisti agonisti gvanilat ciklaze C, postopek za njihovo pripravo in uporabo
KR102431436B1 (ko)	2014-08-29	2022-08-10	테스 파마 에스.알.엘.	α-아미노-β-카복시뮤콘산 세미알데히드 데카복실라제의 억제제
WO2016055901A1 (en)	2014-10-08	2016-04-14	Pfizer Inc.	Substituted amide compounds
AR109950A1 (es)	2016-10-14	2019-02-06	Tes Pharma S R L	INHIBIDORES DE LA ÁCIDO a-AMINO-b-CARBOXIMUCÓNICO SEMIALDEHÍDO DESCARBOXILASA
AR117122A1 (es)	2018-11-20	2021-07-14	Tes Pharma S R L	INHIBIDORES DE LA ÁCIDO a-AMINO-b-CARBOXIMUCÓNICO SEMIALDEHÍDO DESCARBOXILASA
SG11202107614PA (en)	2019-01-18	2021-08-30	Astrazeneca Ab	Pcsk9 inhibitors and methods of use thereof

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE2064092C2 (de) *	1970-12-28	1983-06-01	Bayer Ag, 5090 Leverkusen	Inhibitoren für Glykosidhydrolasen aus Actinomyceten
US4062950A (en) *	1973-09-22	1977-12-13	Bayer Aktiengesellschaft	Amino sugar derivatives
DE2347782C3 (de) *	1973-09-22	1979-10-11	Bayer Ag, 5090 Leverkusen	Aminozuckerderivate, Verfahren zu ihrer Herstellung sowie diese Verbindungen enthaltende Arzneimittel
US4065557A (en) *	1974-03-21	1977-12-27	Bayer Aktiengesellschaft	Amino sugars and their use in improving the meat:fat ratio in animals
USRE29903E (en)	1975-03-19	1979-02-06	American Cyanamid Company	Antibacterial antibiotics AM31α, AM31β and AM31γ
DE2614393C3 (de) *	1976-04-02	1980-04-03	Bayer Ag, 5090 Leverkusen	Aminozucker-Derivate und diese Verbindungen enthaltende Arzneimittel

1979
- 1979-01-31 CA CA000320579A patent/CA1121290A/en not_active Expired
- 1979-02-07 PH PH22174A patent/PH15084A/en unknown
- 1979-02-07 ZA ZA79528A patent/ZA79528B/xx unknown
- 1979-02-07 AU AU44028/79A patent/AU527318B2/en not_active Ceased
- 1979-02-08 IL IL56626A patent/IL56626A0/xx not_active IP Right Cessation
- 1979-02-08 AR AR275445A patent/AR219150A1/es active
- 1979-02-09 US US06/011,002 patent/US4273765A/en not_active Expired - Lifetime
- 1979-02-12 NZ NZ189625A patent/NZ189625A/xx unknown
- 1979-02-12 FR FR7903452A patent/FR2416901A1/fr active Granted
- 1979-02-12 HU HU79HO2138A patent/HU181442B/hu not_active IP Right Cessation
- 1979-02-12 LU LU80906A patent/LU80906A1/de unknown
- 1979-02-13 ES ES477653A patent/ES477653A1/es not_active Expired
- 1979-02-13 DK DK61179A patent/DK149599C/da active
- 1979-02-13 SE SE7901276A patent/SE7901276L/ not_active Application Discontinuation
- 1979-02-13 NO NO790469A patent/NO153011C/no unknown
- 1979-02-13 IE IE274/79A patent/IE47916B1/en not_active IP Right Cessation
- 1979-02-13 GR GR58344A patent/GR72817B/el unknown
- 1979-02-13 MC MC791365A patent/MC1253A1/fr unknown
- 1979-02-13 AT AT0108879A patent/AT367451B/de not_active IP Right Cessation
- 1979-02-13 JP JP1443879A patent/JPS54163511A/ja active Granted
- 1979-02-13 PT PT7969218A patent/PT69218A/pt unknown
- 1979-02-14 YU YU348/79A patent/YU41437B/xx unknown
- 1979-02-14 FI FI790486A patent/FI63062C/fi not_active IP Right Cessation
- 1979-02-14 EP EP79100441A patent/EP0003616B1/de not_active Expired
- 1979-02-14 NL NL7901182A patent/NL7901182A/xx not_active Application Discontinuation
- 1979-02-14 DE DE19792905649 patent/DE2905649A1/de not_active Withdrawn
- 1979-02-14 DE DE7979100441T patent/DE2962165D1/de not_active Expired

Also Published As

Publication number	Publication date
DE2962165D1 (en)	1982-03-25
FI790486A7 (fi)	1979-08-15
DK149599B (da)	1986-08-04
PH15084A (en)	1982-07-02
YU34879A (en)	1983-01-21
EP0003616A2 (de)	1979-08-22
NL7901182A (nl)	1979-08-16
IE47916B1 (en)	1984-07-25
ATA108879A (de)	1981-11-15
CA1121290A (en)	1982-04-06
JPS54163511A (en)	1979-12-26
GR72817B (lt)	1983-12-06
NZ189625A (en)	1981-05-01
ES477653A1 (es)	1980-03-01
EP0003616A3 (en)	1979-09-05
AT367451B (de)	1982-07-12
NO153011B (no)	1985-09-23
LU80906A1 (de)	1980-09-24
JPS643877B2 (lt)	1989-01-23
YU41437B (en)	1987-06-30
FR2416901B1 (lt)	1980-10-24
DK61179A (da)	1979-08-15
NO790469L (no)	1979-08-15
ZA79528B (en)	1980-02-27
US4273765A (en)	1981-06-16
EP0003616B1 (de)	1982-02-24
PT69218A (en)	1979-03-01
DE2905649A1 (de)	1979-08-16
FR2416901A1 (fr)	1979-09-07
DK149599C (da)	1987-06-01
AU527318B2 (en)	1983-02-24
HU181442B (en)	1983-07-28
FI63062C (fi)	1983-04-11
IE790274L (en)	1979-08-14
NO153011C (no)	1986-01-02
IL56626A0 (en)	1979-05-31
FI63062B (fi)	1982-12-31
AU4402879A (en)	1979-08-23
MC1253A1 (fr)	1980-01-14
AR219150A1 (es)	1980-07-31

Legal Events

Date

Code

Title

Description

1995-02-28

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Publication	Publication Date	Title
SE7901276L (sv)	1979-08-15	Aminosockerderivat
ATE12042T1 (de)	1985-03-15	Aminosaeurederivate und ihre therapeutische verwendung.
ES463632A1 (es)	1978-07-16	Procedimiento de preparacion de derivados de la piperidina.
IT1064758B (it)	1985-02-25	Composizioni per rivestimenti
NL930107I2 (nl)	1997-02-03	Verbeteringen van of betrekking hebbende op 2,4-digesubstitueerde thiazoolderivaten.
SE7812232L (sv)	1979-06-02	Korrosionsinhiberande kompositioner
EP0032500A4 (en)	1981-11-24	Preservative compositions.
AR221682A1 (es)	1981-03-13	Procedimiento para la preparacion de derivados de 2(imidazol-4-il,piridil-2-ilo o tiazolil-2-ilo-butil o metiltio-etilamino)-5-(1-naftil-alquilenoxi;1,3-benzodioxolil-alquilenoxi;1,4-benzodioxinilalquilenoxi;1-naftilalquilen;1,3-benzodioxolilalquilen;o 1,4-benzo dioxinilalquilen)-4-pirimidona o 4-pirimidintiona
JPS5278880A (en)	1977-07-02	Trifluoromethylthioor sulfonyl derivatives from cycloheptadine homologues
IT1073249B (it)	1985-04-13	Composizioni per il trattamento di impermeabilizzazione di strutture naturali o artificiali
IL64081A0 (en)	1982-01-31	Novel guanidine derivatives
NO821841L (no)	1982-12-14	Mettede aminocyklitderivater, deres fremstilling og legemiddel inneholdende dem
NL7801261A (nl)	1978-08-08	4-gesubstitueerde aminoderivaten van oleando- mycine.
DK260180A (da)	1980-12-20	Pseudotrisaccharider deres fremstilling og anvendelse som antibakterielle midler
IT7824141A0 (it)	1978-06-02	Procedimento per la depurazione di salamoie.
FI793445A7 (fi)	1981-01-01	Menetelmä uusien, aryylitrifluorietanolia sisältävien farmaseuttisten koostumusten valmivalmistamiseksi.
SE7811798L (sv)	1979-05-24	Farmaceutiska kompositioner, som undertrycker uppkastning av maginnehallet
IT7826443A0 (it)	1978-08-03	Composti di ammido-acrilati per composizioni di rivestimento induribili mediante radiazioni.
BE840449A (fr)	1976-10-07	Composition de protection contre la corrosion
OA07701A (fr)	1985-08-30	Perfectionnements relatifs à des dérivés de benzothiénylglycyl-céphalosporines.
IT7924017A0 (it)	1979-06-29	Perfezionamenti al o relativi al controllo di registro.
AR216153A1 (es)	1979-11-30	Composicion para la inhibicion del adenilato de quinaza
IT7822223A0 (it)	1978-04-12	Insieme di pezzi per la realizzazione di arcate di ponte.
FI812698A7 (fi)	1981-09-01	Menetelmä fungisidisten 2-asyyliamino- bentsimidatsolijohdannaisten valmistamiseksi.
IT8024108A0 (it)	1980-08-11	Derivati del2-solfinil-5-solfonil-1,3,4-tiadiazolo, procedimento per la fabbricazione di questi composti nonche' mezzi fungicidi che licontengono.