SE8004454L - Forfarande for framstellning av oximorfon - Google Patents

Forfarande for framstellning av oximorfon

Info

Publication number: SE8004454L
Authority: SE; Sweden
Prior art keywords: oximorphone; procedure; manufacturing; utilizing; lewis base
Prior art date: 1978-10-19

Application number

SE8004454A

Other languages

English (en)

Swedish (sv)

Inventor

M L Wilson

Original Assignee

Mallinckrodt Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1978-10-19

Filing date

1980-06-16

Publication date

1980-06-16

1980-06-16 Application filed by Mallinckrodt Inc filed Critical Mallinckrodt Inc

1980-06-16 Publication of SE8004454L publication Critical patent/SE8004454L/xx

Links

238000000034 method Methods 0.000 title abstract 2
238000004519 manufacturing process Methods 0.000 title 1
ZOXJGFHDIHLPTG-UHFFFAOYSA-N Boron Chemical compound [B] ZOXJGFHDIHLPTG-UHFFFAOYSA-N 0.000 abstract 1
239000002879 Lewis base Substances 0.000 abstract 1
BRUQQQPBMZOVGD-XFKAJCMBSA-N Oxycodone Chemical compound O=C([C@@H]1O2)CC[C@@]3(O)[C@H]4CC5=CC=C(OC)C2=C5[C@@]13CCN4C BRUQQQPBMZOVGD-XFKAJCMBSA-N 0.000 abstract 1
UQCNKQCJZOAFTQ-ISWURRPUSA-N Oxymorphone Chemical compound O([C@H]1C(CC[C@]23O)=O)C4=C5[C@@]12CCN(C)[C@@H]3CC5=CC=C4O UQCNKQCJZOAFTQ-ISWURRPUSA-N 0.000 abstract 1
229910052796 boron Inorganic materials 0.000 abstract 1
239000003153 chemical reaction reagent Substances 0.000 abstract 1
239000003795 chemical substances by application Substances 0.000 abstract 1
150000007527 lewis bases Chemical class 0.000 abstract 1
229960002085 oxycodone Drugs 0.000 abstract 1
229960005118 oxymorphone Drugs 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D489/00—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula:
- C07D489/06—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula: with a hetero atom directly attached in position 14
- C07D489/08—Oxygen atom

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Polarising Elements (AREA)

SE8004454A 1978-10-19 1980-06-16 Forfarande for framstellning av oximorfon SE8004454L (sv)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US95305678A	1978-10-19	1978-10-19

Publications (1)

Publication Number	Publication Date
SE8004454L true SE8004454L (sv)	1980-06-16

Family

ID=25493512

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
SE8004454A SE8004454L (sv)	1978-10-19	1980-06-16	Forfarande for framstellning av oximorfon

Country Status (16)

Country	Link
JP (1)	JPS55501025A (da)
AU (1)	AU5189779A (da)
BE (1)	BE879494A (da)
CA (1)	CA1108132A (da)
CS (1)	CS211364B2 (da)
DK (1)	DK258280A (da)
ES (1)	ES485154A1 (da)
FI (1)	FI793235A7 (da)
FR (1)	FR2439201A1 (da)
GB (1)	GB2049680A (da)
IL (1)	IL58489A0 (da)
IT (1)	IT7969032A0 (da)
NL (1)	NL7920126A (da)
NO (1)	NO793297L (da)
SE (1)	SE8004454L (da)
WO (1)	WO1980000841A1 (da)

Families Citing this family (35)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4795813A (en) *	1981-08-17	1989-01-03	The Florida Board Of Regents On Behalf Of The Florida State University	Synthesis of derivatives of codeine and other 3-O-alkylmorphines
US5668285A (en) *	1986-10-31	1997-09-16	The United States Of America As Represented By The Department Of Health And Human Services	Total synthesis of northebaine, normophine, noroxymorphone enantiomers and derivatives via N-Nor intermediates
FR2636330B1 (fr) *	1988-09-13	1990-11-30	Sanofi Sa	Procede de preparation de derives de morphinane
AU642447B2 (en) *	1989-10-16	1993-10-21	United States of America, as represented by the Secretary, U.S. Department of Commerce, The	Total synthesis of northebaine, normorphine, noroxymorphone enantiomers and derivatives via N-nor intermediates
US8329216B2 (en)	2001-07-06	2012-12-11	Endo Pharmaceuticals Inc.	Oxymorphone controlled release formulations
EP1404333A1 (en)	2001-07-06	2004-04-07	Endo Pharmaceuticals Inc.	Oxymorphone controlled release formulations
WO2003004033A1 (en)	2001-07-06	2003-01-16	Penwest Pharmaceuticals Company	Sustained release formulations of oxymorphone
US7776314B2 (en)	2002-06-17	2010-08-17	Grunenthal Gmbh	Abuse-proofed dosage system
DE10361596A1 (de)	2003-12-24	2005-09-29	Grünenthal GmbH	Verfahren zur Herstellung einer gegen Missbrauch gesicherten Darreichungsform
US20070048228A1 (en)	2003-08-06	2007-03-01	Elisabeth Arkenau-Maric	Abuse-proofed dosage form
DE10336400A1 (de)	2003-08-06	2005-03-24	Grünenthal GmbH	Gegen Missbrauch gesicherte Darreichungsform
DE102005005446A1 (de)	2005-02-04	2006-08-10	Grünenthal GmbH	Bruchfeste Darreichungsformen mit retardierter Freisetzung
DE102004032049A1 (de)	2004-07-01	2006-01-19	Grünenthal GmbH	Gegen Missbrauch gesicherte, orale Darreichungsform
DE102005005449A1 (de)	2005-02-04	2006-08-10	Grünenthal GmbH	Verfahren zur Herstellung einer gegen Missbrauch gesicherten Darreichungsform
CN101395159A (zh)	2006-03-02	2009-03-25	马林克罗特公司	制备含有低含量α,β-不饱和酮化合物的吗啡烷-6-酮产物的方法
JP5774853B2 (ja)	2008-01-25	2015-09-09	グリュネンタール・ゲゼルシャフト・ミト・ベシュレンクテル・ハフツング	医薬投薬形
MX2010012039A (es)	2008-05-09	2010-11-30	Gruenenthal Gmbh	Proceso para la preparacion de una formulacion de polvo intermedia y una forma de dosificacion solida final bajo el uso de un paso de congelacion por rocio.
BR112012001547A2 (pt)	2009-07-22	2016-03-08	Gruenenthal Gmbh	forma de dosagem farmacêutica extrusada por fusão a quente
ES2428938T3 (es)	2009-07-22	2013-11-12	Grünenthal GmbH	Forma de dosificación resistente a la manipulación y estabilizada frente a la oxidación
CN103179954A (zh)	2010-09-02	2013-06-26	格吕伦塔尔有限公司	包含阴离子聚合物的抗破碎剂型
CA2808219C (en)	2010-09-02	2019-05-14	Gruenenthal Gmbh	Tamper resistant dosage form comprising inorganic salt
PL2736497T3 (pl)	2011-07-29	2018-01-31	Gruenenthal Gmbh	Tabletka odporna na ingerencję, zapewniająca natychmiastowe uwalnianie leku
CA2839123A1 (en)	2011-07-29	2013-02-07	Grunenthal Gmbh	Tamper-resistant tablet providing immediate drug release
MX356421B (es)	2012-02-28	2018-05-29	Gruenenthal Gmbh	Forma de dosificacion resistente a la manipulacion indebida que comprende un compuesto farmacologicamente activo y un polimero anionico.
PL2838512T3 (pl)	2012-04-18	2018-12-31	Grünenthal GmbH	Farmaceutyczna postać dawkowania odporna na niewłaściwe użycie i odporna na uderzeniowe uwalnianie dawki
US10064945B2 (en)	2012-05-11	2018-09-04	Gruenenthal Gmbh	Thermoformed, tamper-resistant pharmaceutical dosage form containing zinc
MX371432B (es)	2013-05-29	2020-01-30	Gruenenthal Gmbh	Forma de dosificacion resistente al uso indebido que contiene una o mas particulas.
WO2014191396A1 (en)	2013-05-29	2014-12-04	Grünenthal GmbH	Tamper resistant dosage form with bimodal release profile
US10624862B2 (en)	2013-07-12	2020-04-21	Grünenthal GmbH	Tamper-resistant dosage form containing ethylene-vinyl acetate polymer
WO2015078891A1 (en)	2013-11-26	2015-06-04	Farmaceutici Formenti S.P.A.	Preparation of a powdery pharmaceutical composition by means of cryo-milling
US20150320690A1 (en)	2014-05-12	2015-11-12	Grünenthal GmbH	Tamper resistant immediate release capsule formulation comprising tapentadol
EP3148512A1 (en)	2014-05-26	2017-04-05	Grünenthal GmbH	Multiparticles safeguarded against ethanolic dose-dumping
BR112017021475A2 (pt)	2015-04-24	2018-07-10	Gruenenthal Gmbh	forma de dosagem resistente à adulteração (tamper) com liberação imediata e resistência contra extração de solvente
AU2016319203A1 (en)	2015-09-10	2018-02-22	Grünenthal GmbH	Protecting oral overdose with abuse deterrent immediate release formulations
ES2701855T3 (es)	2016-05-31	2019-02-26	Alcaliber Investig Desarrollo E Innovacion Slu	Proceso para la obtención de 3,14-diacetiloximorfona a partir de oripavina

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3249616A (en) *		1966-05-03		Ix-dfflydroxy-g-oxo-n-phenethylmor- phinan (cis) and production thereof
US2806033A (en) *	1955-08-03	1957-09-10	Lewenstein	Morphine derivative
US3775414A (en) *	1972-05-10	1973-11-27	Bristol Myers Co	Process for the preparation of 14-hydroxymorphinan derivatives

1979
- 1979-10-12 NO NO793297A patent/NO793297L/no unknown
- 1979-10-18 CA CA337,908A patent/CA1108132A/en not_active Expired
- 1979-10-18 FR FR7925895A patent/FR2439201A1/fr not_active Withdrawn
- 1979-10-18 FI FI793235A patent/FI793235A7/fi not_active Application Discontinuation
- 1979-10-18 AU AU51897/79A patent/AU5189779A/en not_active Abandoned
- 1979-10-18 JP JP50190279A patent/JPS55501025A/ja active Pending
- 1979-10-18 ES ES485154A patent/ES485154A1/es not_active Expired
- 1979-10-18 WO PCT/US1979/000862 patent/WO1980000841A1/en not_active Ceased
- 1979-10-18 BE BE0/197710A patent/BE879494A/fr unknown
- 1979-10-18 IT IT7969032A patent/IT7969032A0/it unknown
- 1979-10-18 NL NL7920126A patent/NL7920126A/nl unknown
- 1979-10-18 GB GB8014422A patent/GB2049680A/en not_active Withdrawn
- 1979-10-18 IL IL58489A patent/IL58489A0/xx unknown
- 1979-10-19 CS CS797115A patent/CS211364B2/cs unknown
1980
- 1980-06-16 SE SE8004454A patent/SE8004454L/xx not_active Application Discontinuation
- 1980-06-17 DK DK258280A patent/DK258280A/da unknown

Also Published As

Publication number	Publication date
FR2439201A1 (fr)	1980-05-16
IL58489A0 (en)	1980-01-31
CS211364B2 (en)	1982-02-26
JPS55501025A (da)	1980-11-27
ES485154A1 (es)	1980-06-16
CA1108132A (en)	1981-09-01
DK258280A (da)	1980-06-17
WO1980000841A1 (en)	1980-05-01
IT7969032A0 (it)	1979-10-18
NO793297L (no)	1980-04-22
BE879494A (fr)	1980-02-15
GB2049680A (en)	1980-12-31
NL7920126A (nl)	1980-08-29
AU5189779A (en)	1980-04-24
FI793235A7 (fi)	1981-01-01

Legal Events

Date	Code	Title	Description
1995-02-28	NAV	Patent application has lapsed	Ref document number: 8004454-8

Publication	Publication Date	Title
SE8004454L (sv)	1980-06-16	Forfarande for framstellning av oximorfon
BR7700342A (pt)	1977-12-06	Processo de fabricacao de cimento portland
YU44033B (en)	1990-02-28	Process for producing vulcanizable coatchouc
EP0020665A4 (en)	1982-04-22	Three-dimensionally structured microelectronic device.
GB1539001A (en)	1979-01-24	Process for making ether sulphonates
RO72326A (ro)	1981-06-30	Procedeu pentru compactarea prafului de silice
SE425614B (sv)	1982-10-18	Differentialvexel
DE3173396D1 (en)	1986-02-13	Tridecapeptide, process for its preparation and its use
YU206777A (en)	1982-10-31	Process for obtaining 7-substituted aminoacetamido-oxadethia-cephalosporin
BR7903036A (pt)	1979-12-04	Molde para a producao de objetos de vidro
RO78266A (ro)	1982-04-12	Procedeu de preparare a unor polimeri hidrosolubili utilizati ca floculanti
RO77138A (ro)	1981-06-22	Procedeu de fabricare a cimentului
SE7704110L (sv)	1977-10-09	Forfarande for framstellning och rening av sekretin
DE2961164D1 (en)	1982-01-07	Process for manufacturing plastic-coated ornamental concrete bricks
HU179757B (en)	1982-12-28	Process for producing aldehydes
DE2962212D1 (en)	1982-03-25	Process for making semiconductor components with optoelectronic conversion properties
JPS5212848A (en)	1977-01-31	Indoor illuminator utilizing solar rays
HU177814B (en)	1981-12-28	Process for producing trisazo-colouring agent
DE2953230A1 (de)	1980-11-27	Process for producing oxymorphone
GB2004557B (en)	1982-03-10	Process for producing phenolic resins
AR223665A1 (es)	1981-09-15	Maquina para la fabricacion de objetos de vidrio
JPS51138980A (en)	1976-11-30	A method of an automatic measureing
JPS5399067A (en)	1978-08-30	Elbow pipe manufacturing process
SE7608911L (sv)	1977-02-12	Forfarande for framstellning av 2-aminometyl-1-etylpyrrolidin
RO78752A (ro)	1982-10-11	Procedeu de obtinere a unui liant carbamidofuranic