SE8004454L - Forfarande for framstellning av oximorfon - Google Patents

Forfarande for framstellning av oximorfon

Info

Publication number: SE8004454L
Authority: SE; Sweden
Prior art keywords: oximorphone; procedure; manufacturing; utilizing; lewis base
Prior art date: 1978-10-19

Application number

SE8004454A

Other languages

English (en)

Swedish (sv)

Inventor

M L Wilson

Original Assignee

Mallinckrodt Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1978-10-19

Filing date

1980-06-16

Publication date

1980-06-16

1980-06-16 Application filed by Mallinckrodt Inc filed Critical Mallinckrodt Inc

1980-06-16 Publication of SE8004454L publication Critical patent/SE8004454L/xx

Links

238000000034 method Methods 0.000 title abstract 2
238000004519 manufacturing process Methods 0.000 title 1
ZOXJGFHDIHLPTG-UHFFFAOYSA-N Boron Chemical compound [B] ZOXJGFHDIHLPTG-UHFFFAOYSA-N 0.000 abstract 1
239000002879 Lewis base Substances 0.000 abstract 1
BRUQQQPBMZOVGD-XFKAJCMBSA-N Oxycodone Chemical compound O=C([C@@H]1O2)CC[C@@]3(O)[C@H]4CC5=CC=C(OC)C2=C5[C@@]13CCN4C BRUQQQPBMZOVGD-XFKAJCMBSA-N 0.000 abstract 1
UQCNKQCJZOAFTQ-ISWURRPUSA-N Oxymorphone Chemical compound O([C@H]1C(CC[C@]23O)=O)C4=C5[C@@]12CCN(C)[C@@H]3CC5=CC=C4O UQCNKQCJZOAFTQ-ISWURRPUSA-N 0.000 abstract 1
229910052796 boron Inorganic materials 0.000 abstract 1
239000003153 chemical reaction reagent Substances 0.000 abstract 1
239000003795 chemical substances by application Substances 0.000 abstract 1
150000007527 lewis bases Chemical class 0.000 abstract 1
229960002085 oxycodone Drugs 0.000 abstract 1
229960005118 oxymorphone Drugs 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D489/00—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula:
- C07D489/06—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula: with a hetero atom directly attached in position 14
- C07D489/08—Oxygen atom

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Polarising Elements (AREA)

SE8004454A 1978-10-19 1980-06-16 Forfarande for framstellning av oximorfon SE8004454L (sv)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US95305678A	1978-10-19	1978-10-19

Publications (1)

Publication Number	Publication Date
SE8004454L true SE8004454L (sv)	1980-06-16

Family

ID=25493512

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
SE8004454A SE8004454L (sv)	1978-10-19	1980-06-16	Forfarande for framstellning av oximorfon

Country Status (16)

Country	Link
JP (1)	JPS55501025A (da)
AU (1)	AU5189779A (da)
BE (1)	BE879494A (da)
CA (1)	CA1108132A (da)
CS (1)	CS211364B2 (da)
DK (1)	DK258280A (da)
ES (1)	ES485154A1 (da)
FI (1)	FI793235A7 (da)
FR (1)	FR2439201A1 (da)
GB (1)	GB2049680A (da)
IL (1)	IL58489A0 (da)
IT (1)	IT7969032A0 (da)
NL (1)	NL7920126A (da)
NO (1)	NO793297L (da)
SE (1)	SE8004454L (da)
WO (1)	WO1980000841A1 (da)

Families Citing this family (35)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4795813A (en) *	1981-08-17	1989-01-03	The Florida Board Of Regents On Behalf Of The Florida State University	Synthesis of derivatives of codeine and other 3-O-alkylmorphines
US5668285A (en) *	1986-10-31	1997-09-16	The United States Of America As Represented By The Department Of Health And Human Services	Total synthesis of northebaine, normophine, noroxymorphone enantiomers and derivatives via N-Nor intermediates
FR2636330B1 (fr) *	1988-09-13	1990-11-30	Sanofi Sa	Procede de preparation de derives de morphinane
CA2067200C (en) *	1989-10-16	1998-06-30	Kenner C. Rice	Total synthesis of northebaine, normorphine, noroxymorphone enantiomers and derivatives via n-nor intermediates
DE60223254T2 (de)	2001-07-06	2008-08-14	Penwest Pharmaceuticals Co.	Verzögert freisetzende formulierungen von oxymorphon
JP2005515966A (ja)	2001-07-06	2005-06-02	エンドーファーマシューティカルズ，インコーポレイティド	鎮痛薬としての使用のための６−ヒドロキシ−オキシモルホンの経口投与
US8329216B2 (en)	2001-07-06	2012-12-11	Endo Pharmaceuticals Inc.	Oxymorphone controlled release formulations
US7776314B2 (en)	2002-06-17	2010-08-17	Grunenthal Gmbh	Abuse-proofed dosage system
DE102005005446A1 (de)	2005-02-04	2006-08-10	Grünenthal GmbH	Bruchfeste Darreichungsformen mit retardierter Freisetzung
US20070048228A1 (en)	2003-08-06	2007-03-01	Elisabeth Arkenau-Maric	Abuse-proofed dosage form
DE10336400A1 (de)	2003-08-06	2005-03-24	Grünenthal GmbH	Gegen Missbrauch gesicherte Darreichungsform
DE10361596A1 (de)	2003-12-24	2005-09-29	Grünenthal GmbH	Verfahren zur Herstellung einer gegen Missbrauch gesicherten Darreichungsform
DE102004032049A1 (de)	2004-07-01	2006-01-19	Grünenthal GmbH	Gegen Missbrauch gesicherte, orale Darreichungsform
DE102005005449A1 (de)	2005-02-04	2006-08-10	Grünenthal GmbH	Verfahren zur Herstellung einer gegen Missbrauch gesicherten Darreichungsform
CN101395159A (zh)	2006-03-02	2009-03-25	马林克罗特公司	制备含有低含量α,β-不饱和酮化合物的吗啡烷-6-酮产物的方法
CA2713128C (en)	2008-01-25	2016-04-05	Gruenenthal Gmbh	Pharmaceutical dosage form
AU2009243681B2 (en)	2008-05-09	2013-12-19	Grunenthal Gmbh	Process for the preparation of an intermediate powder formulation and a final solid dosage form under usage of a spray congealing step
CN102639118B (zh)	2009-07-22	2015-07-29	格吕伦塔尔有限公司	氧化稳定的抗干扰剂型
KR101738369B1 (ko)	2009-07-22	2017-05-22	그뤼넨탈 게엠베하	핫 멜트 압출된 제어 방출 투여형
TWI516286B (zh)	2010-09-02	2016-01-11	歌林達股份有限公司	含陰離子聚合物之抗破碎劑型
BR112013005194A2 (pt)	2010-09-02	2016-05-03	Gruenenthal Gmbh	forma de dosagem resistente à violação compreendendo sal inorgânico
BR112014001091A2 (pt)	2011-07-29	2017-02-14	Gruenenthal Gmbh	comprimido resistente à adulteração que fornece liberação imediata do fármaco
EA201400172A1 (ru)	2011-07-29	2014-06-30	Грюненталь Гмбх	Устойчивая к разрушению таблетка, которая обеспечивает немедленное высвобождение лекарственного средства
MX356421B (es)	2012-02-28	2018-05-29	Gruenenthal Gmbh	Forma de dosificacion resistente a la manipulacion indebida que comprende un compuesto farmacologicamente activo y un polimero anionico.
EP2838512B1 (en)	2012-04-18	2018-08-22	Grünenthal GmbH	Tamper resistant and dose-dumping resistant pharmaceutical dosage form
US10064945B2 (en)	2012-05-11	2018-09-04	Gruenenthal Gmbh	Thermoformed, tamper-resistant pharmaceutical dosage form containing zinc
US9737490B2 (en)	2013-05-29	2017-08-22	Grünenthal GmbH	Tamper resistant dosage form with bimodal release profile
EP3003279A1 (en)	2013-05-29	2016-04-13	Grünenthal GmbH	Tamper-resistant dosage form containing one or more particles
BR112016000194A8 (pt)	2013-07-12	2019-12-31	Gruenenthal Gmbh	forma de dosagem resistente à violação contendo o polímero de acetato de etileno-vinila
EP3073994A1 (en)	2013-11-26	2016-10-05	Grünenthal GmbH	Preparation of a powdery pharmaceutical composition by means of cryo-milling
WO2015173195A1 (en)	2014-05-12	2015-11-19	Grünenthal GmbH	Tamper resistant immediate release capsule formulation comprising tapentadol
EA201692388A1 (ru)	2014-05-26	2017-05-31	Грюненталь Гмбх	Лекарственная форма в виде множества частиц, защищенная от вызываемого этанолом сброса дозы
WO2016170097A1 (en)	2015-04-24	2016-10-27	Grünenthal GmbH	Tamper-resistant dosage form with immediate release and resistance against solvent extraction
JP2018526414A (ja)	2015-09-10	2018-09-13	グリュネンタール・ゲゼルシャフト・ミト・ベシュレンクテル・ハフツング	乱用抑止性の即放性製剤を用いた経口過剰摂取に対する保護
EP3252055B1 (en)	2016-05-31	2018-09-19	Alcaliber Investigacion Desarrollo e Innovacion SLU	Process for obtaining 3,14-diacetyloxymorphone from oripavine

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3249616A (en) *		1966-05-03		Ix-dfflydroxy-g-oxo-n-phenethylmor- phinan (cis) and production thereof
US2806033A (en) *	1955-08-03	1957-09-10	Lewenstein	Morphine derivative
US3775414A (en) *	1972-05-10	1973-11-27	Bristol Myers Co	Process for the preparation of 14-hydroxymorphinan derivatives

1979
- 1979-10-12 NO NO793297A patent/NO793297L/no unknown
- 1979-10-18 FI FI793235A patent/FI793235A7/fi not_active Application Discontinuation
- 1979-10-18 IT IT7969032A patent/IT7969032A0/it unknown
- 1979-10-18 GB GB8014422A patent/GB2049680A/en not_active Withdrawn
- 1979-10-18 WO PCT/US1979/000862 patent/WO1980000841A1/en not_active Ceased
- 1979-10-18 AU AU51897/79A patent/AU5189779A/en not_active Abandoned
- 1979-10-18 IL IL58489A patent/IL58489A0/xx unknown
- 1979-10-18 FR FR7925895A patent/FR2439201A1/fr not_active Withdrawn
- 1979-10-18 NL NL7920126A patent/NL7920126A/nl unknown
- 1979-10-18 BE BE0/197710A patent/BE879494A/fr unknown
- 1979-10-18 ES ES485154A patent/ES485154A1/es not_active Expired
- 1979-10-18 JP JP50190279A patent/JPS55501025A/ja active Pending
- 1979-10-18 CA CA337,908A patent/CA1108132A/en not_active Expired
- 1979-10-19 CS CS797115A patent/CS211364B2/cs unknown
1980
- 1980-06-16 SE SE8004454A patent/SE8004454L/xx not_active Application Discontinuation
- 1980-06-17 DK DK258280A patent/DK258280A/da unknown

Also Published As

Publication number	Publication date
ES485154A1 (es)	1980-06-16
GB2049680A (en)	1980-12-31
NL7920126A (nl)	1980-08-29
NO793297L (no)	1980-04-22
BE879494A (fr)	1980-02-15
IL58489A0 (en)	1980-01-31
JPS55501025A (da)	1980-11-27
FI793235A7 (fi)	1981-01-01
WO1980000841A1 (en)	1980-05-01
CS211364B2 (en)	1982-02-26
CA1108132A (en)	1981-09-01
AU5189779A (en)	1980-04-24
IT7969032A0 (it)	1979-10-18
FR2439201A1 (fr)	1980-05-16
DK258280A (da)	1980-06-17

Legal Events

Date	Code	Title	Description
1995-02-28	NAV	Patent application has lapsed	Ref document number: 8004454-8

Publication	Publication Date	Title
SE8004454L (sv)	1980-06-16	Forfarande for framstellning av oximorfon
BR7700342A (pt)	1977-12-06	Processo de fabricacao de cimento portland
YU44033B (en)	1990-02-28	Process for producing vulcanizable coatchouc
EP0020665A4 (en)	1982-04-22	Three-dimensionally structured microelectronic device.
NL7807983A (nl)	1979-01-30	Werkwijze voor de vervaardiging van een halfgeleiderin- richting.
GB1539001A (en)	1979-01-24	Process for making ether sulphonates
RO72326A (ro)	1981-06-30	Procedeu pentru compactarea prafului de silice
SE425614B (sv)	1982-10-18	Differentialvexel
DE3173396D1 (en)	1986-02-13	Tridecapeptide, process for its preparation and its use
BR7903036A (pt)	1979-12-04	Molde para a producao de objetos de vidro
RO78266A (ro)	1982-04-12	Procedeu de preparare a unor polimeri hidrosolubili utilizati ca floculanti
PT66808B (en)	1978-12-21	Process for preparing 5-m-tolyloxyuracil useful as an anti-ulcer agent
RO77138A (ro)	1981-06-22	Procedeu de fabricare a cimentului
SE7704110L (sv)	1977-10-09	Forfarande for framstellning och rening av sekretin
DE2961164D1 (en)	1982-01-07	Process for manufacturing plastic-coated ornamental concrete bricks
HU179757B (en)	1982-12-28	Process for producing aldehydes
JPS5226859A (en)	1977-02-28	Light source tracer
DE2962212D1 (en)	1982-03-25	Process for making semiconductor components with optoelectronic conversion properties
NL7902225A (nl)	1979-10-09	Werkwijze voor de vervaardiging van bandkernen.
JPS5212848A (en)	1977-01-31	Indoor illuminator utilizing solar rays
DE2953230A1 (de)	1980-11-27	Process for producing oxymorphone
NL7606379A (nl)	1976-12-14	Werkwijze ter bereiding van een antigene samenstelling.
GB2004557B (en)	1982-03-10	Process for producing phenolic resins
AR223665A1 (es)	1981-09-15	Maquina para la fabricacion de objetos de vidrio
DD130031A2 (de)	1978-03-01	Verfahren zur herstellung glasierbarer,dichter sinterkoerper