SE8100238L - Syntetisk gen, plasmidvektor innehallande denna gen, forfaranden for genens och vektorns framstellning och anvendning samt salunda erhallna celler och peptider - Google Patents

Syntetisk gen, plasmidvektor innehallande denna gen, forfaranden for genens och vektorns framstellning och anvendning samt salunda erhallna celler och peptider

Info

Publication number: SE8100238L
Authority: SE; Sweden
Prior art keywords: genes; gene; plasmid vectors; peptides; salunda
Prior art date: 1980-01-30

Application number

SE8100238A

Other languages

English (en)

Other versions

SE451595B (sv

Inventor

N H Carey

J S Emtage

M T Doel

M A William

Original Assignee

Searle & Co

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1980-01-30

Filing date

1981-01-16

Publication date

1981-07-31

1981-01-16 Application filed by Searle & Co filed Critical Searle & Co

1981-07-31 Publication of SE8100238L publication Critical patent/SE8100238L/sv

1987-10-19 Publication of SE451595B publication Critical patent/SE451595B/sv

Links

108700005078 Synthetic Genes Proteins 0.000 title abstract 4
108090000765 processed proteins & peptides Proteins 0.000 title abstract 3
108090000623 proteins and genes Proteins 0.000 title abstract 3
238000000034 method Methods 0.000 title abstract 2
239000013600 plasmid vector Substances 0.000 title abstract 2
102000004196 processed proteins & peptides Human genes 0.000 title abstract 2
239000013598 vector Substances 0.000 title 1
108091034117 Oligonucleotide Proteins 0.000 abstract 2
JLCPHMBAVCMARE-UHFFFAOYSA-N [3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[5-(2-amino-6-oxo-1H-purin-9-yl)-3-[[3-[[3-[[3-[[3-[[3-[[5-(2-amino-6-oxo-1H-purin-9-yl)-3-[[5-(2-amino-6-oxo-1H-purin-9-yl)-3-hydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methyl [5-(6-aminopurin-9-yl)-2-(hydroxymethyl)oxolan-3-yl] hydrogen phosphate Polymers Cc1cn(C2CC(OP(O)(=O)OCC3OC(CC3OP(O)(=O)OCC3OC(CC3O)n3cnc4c3nc(N)[nH]c4=O)n3cnc4c3nc(N)[nH]c4=O)C(COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3CO)n3cnc4c(N)ncnc34)n3ccc(N)nc3=O)n3cnc4c(N)ncnc34)n3ccc(N)nc3=O)n3ccc(N)nc3=O)n3ccc(N)nc3=O)n3cnc4c(N)ncnc34)n3cnc4c(N)ncnc34)n3cc(C)c(=O)[nH]c3=O)n3cc(C)c(=O)[nH]c3=O)n3ccc(N)nc3=O)n3cc(C)c(=O)[nH]c3=O)n3cnc4c3nc(N)[nH]c4=O)n3cnc4c(N)ncnc34)n3cnc4c(N)ncnc34)n3cnc4c(N)ncnc34)n3cnc4c(N)ncnc34)O2)c(=O)[nH]c1=O JLCPHMBAVCMARE-UHFFFAOYSA-N 0.000 abstract 2
YZQCXOFQZKCETR-UWVGGRQHSA-N Asp-Phe Chemical compound OC(=O)C[C@H](N)C(=O)N[C@H](C(O)=O)CC1=CC=CC=C1 YZQCXOFQZKCETR-UWVGGRQHSA-N 0.000 abstract 1
108010011485 Aspartame Proteins 0.000 abstract 1
108091033380 Coding strand Proteins 0.000 abstract 1
108020004705 Codon Proteins 0.000 abstract 1
150000001413 amino acids Chemical class 0.000 abstract 1
239000000605 aspartame Substances 0.000 abstract 1
IAOZJIPTCAWIRG-QWRGUYRKSA-N aspartame Chemical compound OC(=O)C[C@H](N)C(=O)N[C@H](C(=O)OC)CC1=CC=CC=C1 IAOZJIPTCAWIRG-QWRGUYRKSA-N 0.000 abstract 1
229960003438 aspartame Drugs 0.000 abstract 1
235000010357 aspartame Nutrition 0.000 abstract 1
108010069205 aspartyl-phenylalanine Proteins 0.000 abstract 1
235000003599 food sweetener Nutrition 0.000 abstract 1
238000001338 self-assembly Methods 0.000 abstract 1
239000003765 sweetening agent Substances 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06104—Dipeptides with the first amino acid being acidic
- C07K5/06113—Asp- or Asn-amino acid
- C07K5/06121—Asp- or Asn-amino acid the second amino acid being aromatic or cycloaliphatic
- C07K5/0613—Aspartame
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P13/00—Preparation of nitrogen-containing organic compounds
- C12P13/04—Alpha- or beta- amino acids
- C12P13/20—Aspartic acid; Asparagine
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P13/00—Preparation of nitrogen-containing organic compounds
- C12P13/04—Alpha- or beta- amino acids
- C12P13/22—Tryptophan; Tyrosine; Phenylalanine; 3,4-Dihydroxyphenylalanine
- C12P13/222—Phenylalanine
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P21/00—Preparation of peptides or proteins
- C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Engineering & Computer Science (AREA)
Health & Medical Sciences (AREA)
Genetics & Genomics (AREA)
Wood Science & Technology (AREA)
Zoology (AREA)
Biochemistry (AREA)
Biotechnology (AREA)
General Health & Medical Sciences (AREA)
Molecular Biology (AREA)
Bioinformatics & Cheminformatics (AREA)
General Engineering & Computer Science (AREA)
Microbiology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Biophysics (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Biomedical Technology (AREA)
Medicinal Chemistry (AREA)
Physics & Mathematics (AREA)
Plant Pathology (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)
Peptides Or Proteins (AREA)
Saccharide Compounds (AREA)

SE8100238A 1980-01-30 1981-01-16 Plasmidvektor innehallande en syntetisk gen for expression av de repetitiva polypeptiderna(aspartyl-fenylalanin)n, der n er ett heltal av minst 2 samt e.coli transformerad med vektorn SE451595B (sv)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
GB8003191		1980-01-30

Publications (2)

Publication Number	Publication Date
SE8100238L true SE8100238L (sv)	1981-07-31
SE451595B SE451595B (sv)	1987-10-19

Family

ID=10511011

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
SE8100238A SE451595B (sv)	1980-01-30	1981-01-16	Plasmidvektor innehallande en syntetisk gen for expression av de repetitiva polypeptiderna(aspartyl-fenylalanin)n, der n er ett heltal av minst 2 samt e.coli transformerad med vektorn

Country Status (14)

Country	Link
JP (1)	JPS579795A (sv)
AU (1)	AU545908B2 (sv)
BE (1)	BE887290A (sv)
CA (1)	CA1189466A (sv)
CH (1)	CH662821A5 (sv)
DE (1)	DE3102721A1 (sv)
DK (1)	DK17881A (sv)
ES (1)	ES8203965A1 (sv)
FR (1)	FR2479259B1 (sv)
IE (1)	IE50833B1 (sv)
IL (1)	IL61952A (sv)
IT (1)	IT1170653B (sv)
NL (1)	NL8100437A (sv)
SE (1)	SE451595B (sv)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DK159976C (da) *	1979-06-01	1991-05-27	Searle & Co	Plasmidvektorer, fremgangsmaade til fremstilling deraf, bakterieceller transformeret med plasmidvektorer samt udtrykkelse af protein i transformerede bakterieceller
CA1213537A (en) *	1984-05-01	1986-11-04	Canadian Patents And Development Limited - Societe Canadienne Des Brevets Et D'exploitation Limitee	Polypeptide expression method
WO2000017336A1 (en) *	1998-09-19	2000-03-30	Sang Jun Lee	Dna cassette encoding a multimer of a biologically active peptide and a cleavable linker attached thereto and process for preparing the biologically active peptide

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP0036258A3 (en) *	1980-03-14	1982-02-10	Cetus Corporation	Process for producing aspartame

1981
- 1981-01-15 DK DK17881A patent/DK17881A/da not_active Application Discontinuation
- 1981-01-15 IE IE71/81A patent/IE50833B1/en unknown
- 1981-01-16 SE SE8100238A patent/SE451595B/sv not_active IP Right Cessation
- 1981-01-21 AU AU66507/81A patent/AU545908B2/en not_active Ceased
- 1981-01-21 IL IL61952A patent/IL61952A/xx unknown
- 1981-01-27 IT IT47639/81A patent/IT1170653B/it active
- 1981-01-28 DE DE3102721A patent/DE3102721A1/de active Granted
- 1981-01-29 NL NL8100437A patent/NL8100437A/nl not_active Application Discontinuation
- 1981-01-29 CH CH585/81A patent/CH662821A5/fr not_active IP Right Cessation
- 1981-01-29 BE BE0/203639A patent/BE887290A/fr not_active IP Right Cessation
- 1981-01-29 CA CA000369648A patent/CA1189466A/en not_active Expired
- 1981-01-29 ES ES498948A patent/ES8203965A1/es not_active Expired
- 1981-01-29 FR FR8101707A patent/FR2479259B1/fr not_active Expired
- 1981-01-29 JP JP1218481A patent/JPS579795A/ja active Pending

Also Published As

Publication number	Publication date
IL61952A0 (en)	1981-02-27
IT8147639A0 (it)	1981-01-27
FR2479259A1 (fr)	1981-10-02
DK17881A (da)	1981-07-31
IE50833B1 (en)	1986-07-23
CA1189466A (en)	1985-06-25
IL61952A (en)	1984-09-30
ES498948A0 (es)	1982-04-16
JPS579795A (en)	1982-01-19
SE451595B (sv)	1987-10-19
AU6650781A (en)	1981-08-06
ES8203965A1 (es)	1982-04-16
IT1170653B (it)	1987-06-03
DE3102721A1 (de)	1982-01-07
AU545908B2 (en)	1985-08-08
NL8100437A (nl)	1981-09-01
BE887290A (fr)	1981-05-14
FR2479259B1 (fr)	1985-07-12
IE810071L (en)	1981-07-30
DE3102721C2 (sv)	1988-11-10
CH662821A5 (fr)	1987-10-30

Legal Events

Date

Code

Title

Description

1995-01-31

NUG

Patent has lapsed

Ref document number: 8100238-8

Effective date: 19910805

Format of ref document f/p: F

Publication	Publication Date	Title
EP0305488A4 (en)	1991-06-05	Mycobacterial recombinants and peptides
ES2009238A6 (es)	1989-09-16	Metodo para producir proteinas de mycobacterium tuberculosis y peptidos antigenicos de las mismas.
CA2195625A1 (en)	1996-02-08	Ubiquitin-Lytic Peptide Fusion Gene Constructs, Protein Products Deriving Therefrom, and Methods of Making and Using Same
PL317722A1 (en)	1997-04-28	Sequences of synthetic leader peptides
CA2168429A1 (en)	1995-02-09	Expression of fusion polypeptides transported out of cytoplasm without leader sequences
EP0260148A3 (en)	1989-06-07	Improved recombinant expression method, vector and transformed cells
CA2263889A1 (en)	1998-03-05	P-selectin ligand proteins
WO1997020935A3 (en)	1997-08-28	Viral vectors
WO1996017941A3 (en)	1996-08-22	Production of c-terminal amidated peptides from recombinant protein constructs
NO940736D0 (no)	1994-03-03	DNA sekvenser som koder for gelonin polypeptid
CA2147623A1 (en)	1994-05-11	Novel p-selectin ligand protein
EP0101309A3 (en)	1984-12-27	Molecular cloning and characterization of a gene sequence coding for human relaxin
WO1995030001A3 (en)	1996-01-11	Novel p-selectin ligand protein
IE840387L (en)	1984-08-21	SYNTHESIS OF hpGRF(SOMATOCRININ) IN LIQUID PHASE AND¹INTERMEDIATE PEPTIDES
SE8100238L (sv)	1981-07-31	Syntetisk gen, plasmidvektor innehallande denna gen, forfaranden for genens och vektorns framstellning och anvendning samt salunda erhallna celler och peptider
EP0237157A3 (en)	1989-04-05	Vector and method for achieving high level expression in cells
AU5776799A (en)	2000-03-14	Modified hcv peptide vaccines
GR3027636T3 (en)	1998-11-30	Anti-feline immunodeficiency virus (fiv) vaccines.
CO4480058A1 (es)	1997-07-09	Genes codificantes y procedimiento de expresion de una nueva enzima: ftalil amidasa
NO175872C (no)	1994-12-21	Plasmidvektor, fremgangsmåte for fremstilling av peptider og myelomcelle
DE3380495D1 (en)	1989-10-05	Molecular cloning and characterization of the gene sequence coding for porcine relaxin
RU93005218A (ru)	1996-09-20	Полипептид, нуклеотидная последовательность, вектор, клетка, композиция, применение полипептида, способ получения полипептида
PE34296A1 (es)	1996-09-04	Procedimiento para expresion extra-celular de proteina
CA2256125A1 (en)	2000-06-23	Chimeric gene formed of the dna sequences that encode the antigenic determinants of four proteins of l. infantum, useful for serologic diagnosis of canine leishmaniasis and protein obtained
ES2008391A6 (es)	1989-07-16	Un metodo para producir isopenicilina n sintetasa.