SE8200424L - ((1-bensyl-1h-indazol-3-yl)oxi)ettiksyrasalt med lysin - Google Patents
((1-bensyl-1h-indazol-3-yl)oxi)ettiksyrasalt med lysinInfo
- Publication number
- SE8200424L SE8200424L SE8200424A SE8200424A SE8200424L SE 8200424 L SE8200424 L SE 8200424L SE 8200424 A SE8200424 A SE 8200424A SE 8200424 A SE8200424 A SE 8200424A SE 8200424 L SE8200424 L SE 8200424L
- Authority
- SE
- Sweden
- Prior art keywords
- bendazac
- lysine
- indazol
- oxy
- benzyl
- Prior art date
Links
- KDXKERNSBIXSRK-UHFFFAOYSA-N Lysine Natural products NCCCCC(N)C(O)=O KDXKERNSBIXSRK-UHFFFAOYSA-N 0.000 title abstract 2
- 239000004472 Lysine Substances 0.000 title abstract 2
- 150000003839 salts Chemical class 0.000 title abstract 2
- -1 (1-BENZYL-1H-INDAZOL-3-YL) OXY Chemical class 0.000 title 1
- 239000002253 acid Substances 0.000 title 1
- BYFMCKSPFYVMOU-UHFFFAOYSA-N bendazac Chemical compound C12=CC=CC=C2C(OCC(=O)O)=NN1CC1=CC=CC=C1 BYFMCKSPFYVMOU-UHFFFAOYSA-N 0.000 abstract 7
- 229960005149 bendazac Drugs 0.000 abstract 6
- 239000008280 blood Substances 0.000 abstract 2
- 210000004369 blood Anatomy 0.000 abstract 2
- 230000001225 therapeutic effect Effects 0.000 abstract 2
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 150000002632 lipids Chemical class 0.000 abstract 1
- 238000011282 treatment Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/54—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings condensed with carbocyclic rings or ring systems
- C07D231/56—Benzopyrazoles; Hydrogenated benzopyrazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/415—1,2-Diazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Engineering & Computer Science (AREA)
- Obesity (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT23768/80A IT1131779B (it) | 1980-07-29 | 1980-07-29 | Sale dell'acido (1-benzil-1h-indazol-3-il)-ossiacetico con la lisina e procedimento per la sua preparazione |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| SE8200424L true SE8200424L (sv) | 1983-07-28 |
| SE455306B SE455306B (sv) | 1988-07-04 |
Family
ID=11209809
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SE8200424A SE455306B (sv) | 1980-07-29 | 1982-01-27 | Lysinsalt av /(1-bensyl-1h-indazol-3-yl)oxi/-ettiksyra |
| SE8302552A SE8302552L (sv) | 1980-07-29 | 1983-05-04 | ( (1-bensyl-1h-indazol-3-yl)oxi) ettiksyrasalt med lysin |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SE8302552A SE8302552L (sv) | 1980-07-29 | 1983-05-04 | ( (1-bensyl-1h-indazol-3-yl)oxi) ettiksyrasalt med lysin |
Country Status (17)
| Country | Link |
|---|---|
| US (1) | US4352813A (sv) |
| JP (1) | JPS5753465A (sv) |
| AR (1) | AR227677A1 (sv) |
| AU (1) | AU536243B2 (sv) |
| BE (1) | BE891914A (sv) |
| BG (1) | BG60797B2 (sv) |
| CA (1) | CA1166643A (sv) |
| CH (1) | CH651556A5 (sv) |
| DE (1) | DE3202561A1 (sv) |
| ES (1) | ES8203850A1 (sv) |
| FR (1) | FR2489318B1 (sv) |
| GB (1) | GB2081708B (sv) |
| IT (1) | IT1131779B (sv) |
| MX (1) | MX156471A (sv) |
| NL (1) | NL8200222A (sv) |
| PT (1) | PT73365B (sv) |
| SE (2) | SE455306B (sv) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT1189052B (it) * | 1981-11-27 | 1988-01-28 | Acraf | Trattamento della cataratta |
| IT1194564B (it) * | 1983-04-18 | 1988-09-22 | Acraf | Impiego del bendazac e dei suoi sali nel trattamento della retinite pigmentosa |
| IT1230441B (it) | 1989-02-07 | 1991-10-23 | Acraf | Eteri della serie dell'indazolo |
| IT1229674B (it) * | 1989-04-26 | 1991-09-06 | Acraf | Composizione farmaceutica per uso topico oftalmico contenente bendazac o 5-0h bendazac |
| US5217983A (en) * | 1992-03-27 | 1993-06-08 | Du Pont Merck Pharmaceutical Company | (N-benzyl) acetaldehyde bicyclic heterocycles useful as topical antiinflammatories |
| US5272169A (en) * | 1992-03-27 | 1993-12-21 | The Dupont Merck Pharmaceutical Company | (N-benzyl) acetaldehyde bicyclic heterocycles useful as topical antiinflammatories |
| IT1293794B1 (it) * | 1997-07-28 | 1999-03-10 | Acraf | Farmaco attivo nel ridurre la produzione di proteina mcp-1 |
| ITMI20062254A1 (it) * | 2006-11-24 | 2008-05-25 | Acraf | Uso di un acido metossi-alcanoico dell'indazolo per preparare una composizione farmaceutca |
| CN103641784B (zh) * | 2013-12-03 | 2018-06-19 | 杭州民生药业有限公司 | 一种苄达赖氨酸合成工艺 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL28032A (en) * | 1966-08-29 | 1971-08-25 | Acraf | Indazol-3-yl-oxyalkanoic acids and process for the preparation thereof |
| FR1530097A (fr) | 1966-08-29 | 1968-06-21 | Acraf | Acides indazole-3-yl-oxyalcanoïques et procédé pour leur préparation |
| NL6717184A (sv) * | 1967-12-16 | 1969-06-18 | Stamicarbon | |
| FR2217003A1 (en) * | 1973-02-14 | 1974-09-06 | Inst Investigaciones Terapeuti | Benzopyrilacetic acid deriv prepn - by reacting 1-(p-chlorobenzoyl-2-methyl)-5-methoxy-benzopyrilacetic acid with a base |
| DE2940373A1 (de) * | 1979-10-05 | 1981-04-23 | Troponwerke GmbH & Co KG, 5000 Köln | Lysin-(1-(p-chlorbenzoyl)-5-methoxy-2-methyl-3-indol) -acetoxy-acetate, verfahren zu ihrer herstellung und ihre verwendung in arzneimitteln |
-
1980
- 1980-07-29 IT IT23768/80A patent/IT1131779B/it active Protection Beyond IP Right Term
-
1981
- 1981-06-02 US US06/269,923 patent/US4352813A/en not_active Expired - Lifetime
- 1981-06-18 GB GB8118767A patent/GB2081708B/en not_active Expired
- 1981-06-23 MX MX187939A patent/MX156471A/es unknown
- 1981-06-29 ES ES503509A patent/ES8203850A1/es not_active Expired
- 1981-07-14 PT PT73365A patent/PT73365B/pt unknown
- 1981-07-15 AR AR286096A patent/AR227677A1/es active
- 1981-07-27 FR FR8114549A patent/FR2489318B1/fr not_active Expired
- 1981-07-28 JP JP56119033A patent/JPS5753465A/ja active Granted
-
1982
- 1982-01-21 NL NL8200222A patent/NL8200222A/nl not_active Application Discontinuation
- 1982-01-26 CH CH457/82A patent/CH651556A5/fr not_active IP Right Cessation
- 1982-01-26 CA CA000394976A patent/CA1166643A/en not_active Expired
- 1982-01-27 SE SE8200424A patent/SE455306B/sv not_active IP Right Cessation
- 1982-01-27 BE BE0/207152A patent/BE891914A/fr not_active IP Right Cessation
- 1982-01-27 DE DE19823202561 patent/DE3202561A1/de active Granted
- 1982-01-27 AU AU79870/82A patent/AU536243B2/en not_active Ceased
-
1983
- 1983-05-04 SE SE8302552A patent/SE8302552L/sv not_active Application Discontinuation
-
1994
- 1994-02-24 BG BG098555A patent/BG60797B2/bg unknown
Also Published As
| Publication number | Publication date |
|---|---|
| US4352813A (en) | 1982-10-05 |
| SE8302552L (sv) | 1983-07-28 |
| PT73365B (en) | 1982-09-23 |
| NL8200222A (nl) | 1983-08-16 |
| CH651556A5 (en) | 1985-09-30 |
| AU7987082A (en) | 1983-08-04 |
| GB2081708B (en) | 1984-06-20 |
| JPH0322384B2 (sv) | 1991-03-26 |
| PT73365A (en) | 1981-08-01 |
| SE8302552D0 (sv) | 1983-05-04 |
| FR2489318B1 (fr) | 1986-01-03 |
| AU536243B2 (en) | 1984-05-03 |
| SE455306B (sv) | 1988-07-04 |
| BE891914A (fr) | 1982-05-17 |
| ES503509A0 (es) | 1982-04-01 |
| BG60797B2 (bg) | 1996-03-29 |
| MX156471A (es) | 1988-08-26 |
| JPS5753465A (en) | 1982-03-30 |
| GB2081708A (en) | 1982-02-24 |
| AR227677A1 (es) | 1982-11-30 |
| CA1166643A (en) | 1984-05-01 |
| FR2489318A1 (fr) | 1982-03-05 |
| DE3202561A1 (de) | 1983-08-04 |
| IT1131779B (it) | 1986-06-25 |
| IT8023768A0 (it) | 1980-07-29 |
| ES8203850A1 (es) | 1982-04-01 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| NAL | Patent in force |
Ref document number: 8200424-3 Format of ref document f/p: F |
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| NUG | Patent has lapsed |
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