SE8201013L - Forfarande for framstellning av nya, optiskt aktiva antracyklinoner - Google Patents

Forfarande for framstellning av nya, optiskt aktiva antracyklinoner

Info

Publication number
SE8201013L
SE8201013L SE8201013A SE8201013A SE8201013L SE 8201013 L SE8201013 L SE 8201013L SE 8201013 A SE8201013 A SE 8201013A SE 8201013 A SE8201013 A SE 8201013A SE 8201013 L SE8201013 L SE 8201013L
Authority
SE
Sweden
Prior art keywords
optically active
preparation
procedure
new optically
anthracyclinones
Prior art date
Application number
SE8201013A
Other languages
English (en)
Other versions
SE453185B (sv
Inventor
F Arcamone
A Dimarco
L Bernardi
B Patelli
Original Assignee
Farmaceutici Italia
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Farmaceutici Italia filed Critical Farmaceutici Italia
Publication of SE8201013L publication Critical patent/SE8201013L/sv
Publication of SE453185B publication Critical patent/SE453185B/sv

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/24—Condensed ring systems having three or more rings
    • C07H15/252—Naphthacene radicals, e.g. daunomycins, adriamycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biotechnology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Claims (1)

1. PATENTERAV Pdrfarande fdr framstAllning av nya optiskt aktiva antracyklinoner med de allmanna formlerna vari a) RI betecknar vAte cat R2 och R3 Ar lika och betecknar vate, metyl, metoxi, klor eller brom,
SE8201013A 1975-01-22 1982-02-18 Forfarande for framstellning av optiskt aktiva antracyklinoner SE453185B (sv)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB2691/75A GB1500421A (en) 1975-01-22 1975-01-22 Optically active anthracyclinones

Publications (2)

Publication Number Publication Date
SE8201013L true SE8201013L (sv) 1982-02-18
SE453185B SE453185B (sv) 1988-01-18

Family

ID=9744103

Family Applications (4)

Application Number Title Priority Date Filing Date
SE7600563A SE435498B (sv) 1975-01-22 1976-01-20 Forfarande for optisk isomer-uppdelning av racemisk 1,4-dimetoxi-6-hydroxi-6-acetyl-tetrahydronaftalen
SE8201013A SE453185B (sv) 1975-01-22 1982-02-18 Forfarande for framstellning av optiskt aktiva antracyklinoner
SE8201014A SE461525B (sv) 1975-01-22 1982-02-18 Foerfarande foer framstaellning av nya, optiskt aktiva antracyklinoner
SE8201015A SE461529B (sv) 1975-01-22 1982-02-18 Foerfarande foer framstaellning av nya, optiskt aktiva daunos-aminylderivat av antracyklinoner

Family Applications Before (1)

Application Number Title Priority Date Filing Date
SE7600563A SE435498B (sv) 1975-01-22 1976-01-20 Forfarande for optisk isomer-uppdelning av racemisk 1,4-dimetoxi-6-hydroxi-6-acetyl-tetrahydronaftalen

Family Applications After (2)

Application Number Title Priority Date Filing Date
SE8201014A SE461525B (sv) 1975-01-22 1982-02-18 Foerfarande foer framstaellning av nya, optiskt aktiva antracyklinoner
SE8201015A SE461529B (sv) 1975-01-22 1982-02-18 Foerfarande foer framstaellning av nya, optiskt aktiva daunos-aminylderivat av antracyklinoner

Country Status (18)

Country Link
US (1) US4077988A (sv)
JP (4) JPS6033819B2 (sv)
AT (1) AT342035B (sv)
AU (1) AU500067B2 (sv)
BE (1) BE837756A (sv)
CA (1) CA1064920A (sv)
CH (3) CH622486A5 (sv)
DE (2) DE2601785C2 (sv)
DK (1) DK155518C (sv)
ES (1) ES444494A1 (sv)
FR (4) FR2320105A1 (sv)
GB (1) GB1500421A (sv)
HK (1) HK1082A (sv)
MX (1) MX4278E (sv)
NL (1) NL179724C (sv)
SE (4) SE435498B (sv)
SU (5) SU683613A3 (sv)
ZA (1) ZA76292B (sv)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4070382A (en) * 1975-11-18 1978-01-24 Research Corporation Intermediates for polycyclic quinoid antibiotics
GB1527050A (en) * 1976-06-19 1978-10-04 Farmaceutici Italia Optically active anthracyclinones
US4134903A (en) * 1976-08-07 1979-01-16 Societa Farmaceutici Italia S.P.A. Anthracycline ethers and their preparation
GB1573036A (en) * 1977-05-05 1980-08-13 Farmaceutici Italia Anthracyclines
GB1573037A (en) * 1977-05-05 1980-08-13 Farmaceutici Italia Anthracyclines
US4296105A (en) * 1978-08-03 1981-10-20 Institut International De Pathologie Cellulaire Et Moleculaire Derivatives of doxorubicine, their preparation and use
NL8001417A (nl) * 1979-03-17 1980-09-19 Erba Farmitalia Antitumorglycosiden.
US4259476A (en) * 1979-04-02 1981-03-31 Kende Andrew S Novel heterocyclic anthracycline compounds
BE884828A (fr) * 1979-08-20 1981-02-19 Hoffmann La Roche Derives de naphtacene
GB2056443B (en) * 1979-08-20 1984-01-18 Hoffmann La Roche Cyclic compounds
GB2071084B (en) * 1980-01-22 1984-02-29 Hoffmann La Roche Polycylic compounds
JPS5756494A (en) * 1980-09-22 1982-04-05 Microbial Chem Res Found New anthracyclin derivative
ES8308301A1 (es) * 1981-07-29 1983-08-16 Sumitomo Chemical Co Un procedimiento para la preparacion de derivados de aminonaftaceno.
BE896743A (fr) * 1982-08-13 1983-09-16 Erba Farmitalia Synthese de naphtacenequinone.
US4489206A (en) * 1983-05-13 1984-12-18 Adria Laboratories, Inc. Synthesis of (+)-4-demethoxydaunomycinone
US4831019A (en) * 1983-10-31 1989-05-16 Adria Laboratories, Inc. Pharmaceutical preparations of 4-demethoxy-n-trifluoroacetyl anthracyclines
US4496485A (en) * 1983-11-25 1985-01-29 G. D. Searle & Co. Asymmetric 7-O-(substituted acetyl)-4-demethoxydaunomycinones
GB8519452D0 (en) * 1985-08-02 1985-09-11 Erba Farmitalia Injectable solutions
JP2736255B2 (ja) * 1987-03-11 1998-04-02 フアルマシア・エ・アツプジヨン・エツセ・ピー・アー イムノグロブリン結合体
NZ224252A (en) * 1987-04-21 1991-09-25 Erba Carlo Spa An anthracycline glycoside and its preparation
GB8803301D0 (en) * 1988-02-12 1988-03-09 Erba Carlo Spa Process for preparation of 4-demethoxy-daunomycinone aglycone of 4-demethoxy-daunorubicin
GB8824947D0 (en) * 1988-10-25 1988-11-30 Erba Carlo Spa New 4-substituted anthracyclinones & process for preparing them
NL9001834A (nl) * 1990-08-16 1992-03-16 Pharmachemie Bv Nieuwe antracyclineverbindingen met anti-tumorwerkzaamheid, nieuwe tussenverbindingen voor de bereiding van deze antracyclineverbindingen, alsmede preparaten die de aktieve antracyclineverbindingen bevatten.
GB9418260D0 (en) * 1994-09-09 1994-10-26 Erba Carlo Spa Anthracycline derivatives
IT1317106B1 (it) * 2000-11-16 2003-05-26 Menarini Ricerche Spa Processo per la sintesi di antracicline otticamente attive.
DE10155016A1 (de) * 2001-11-07 2003-05-15 Knoell Hans Forschung Ev Neue Chinon-Verbindung, Verfahren zur Herstellung und deren Verwendung

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3904632A (en) * 1972-05-08 1975-09-09 Hoffmann La Roche (')-di-o-isopropylidene-2-keto-l-gulonates
JPS5840556A (ja) * 1981-09-04 1983-03-09 Ricoh Co Ltd 電子写真圧力定着転写紙及びその転写紙用原紙の製造法

Also Published As

Publication number Publication date
SE8201015L (sv) 1982-02-18
JPS59231037A (ja) 1984-12-25
DE2601785A1 (de) 1976-07-29
GB1500421A (en) 1978-02-08
SE435498B (sv) 1984-10-01
AT342035B (de) 1978-03-10
FR2320085A1 (fr) 1977-03-04
SE7600563L (sv) 1976-07-23
FR2320086A1 (fr) 1977-03-04
SU683613A3 (ru) 1979-08-30
CH622530A5 (sv) 1981-04-15
BE837756A (fr) 1976-07-22
FR2320105B1 (sv) 1982-07-23
AU1043276A (en) 1977-07-28
NL179724B (nl) 1986-06-02
DK155518C (da) 1989-08-28
SE461529B (sv) 1990-02-26
SE461525B (sv) 1990-02-26
JPS59231038A (ja) 1984-12-25
MX4278E (es) 1982-03-11
SE8201014L (sv) 1982-02-18
CA1064920A (en) 1979-10-23
NL7600075A (nl) 1976-07-26
FR2320085B1 (sv) 1978-11-03
JPS59231098A (ja) 1984-12-25
CH624085A5 (sv) 1981-07-15
ZA76292B (en) 1977-01-26
US4077988A (en) 1978-03-07
ES444494A1 (es) 1977-05-16
SU776557A3 (ru) 1980-10-30
FR2333769A1 (fr) 1977-07-01
JPS6033819B2 (ja) 1985-08-05
FR2320105A1 (fr) 1977-03-04
DK20376A (da) 1976-08-02
FR2333769B1 (sv) 1979-07-06
JPS5198264A (en) 1976-08-30
CH622486A5 (sv) 1981-04-15
ATA30676A (de) 1977-07-15
DE2601785C2 (de) 1985-10-03
AU500067B2 (en) 1979-05-10
SU724087A3 (ru) 1980-03-25
HK1082A (en) 1982-01-22
DE2660848C2 (de) 1986-02-06
DK155518B (da) 1989-04-17
JPH036157B2 (sv) 1991-01-29
SE453185B (sv) 1988-01-18
NL179724C (nl) 1986-11-03
FR2320086B1 (sv) 1978-11-03
SU646914A3 (ru) 1979-02-05
SU650498A3 (ru) 1979-02-28

Similar Documents

Publication Publication Date Title
ES444494A1 (es) Procedimiento para la preparacion de antracicliononas opti- camente activas.
SU578900A3 (ru) Способ получени изомальтита
CA1006231A (en) Disposable electro-surgical cautery
CA1033102A (en) Anti-fog surgical face mask
CA994796A (fr) Sulfones derivees de dimethyl-1,5 hexadiene-1,5 ylene
AU473084B2 (en) Surgical operation tables
AU464773B2 (en) BENZO-l, 2, 4-TRIAZINE-l, 4-DIN-OXIDES THEIR PRODUCTION, AND THEIR MEDICAL USE
AU6327086A (en) Novel polyoxygenated labdane derivatives, processes for their preparation and their use as medicaments
CA1023750A (en) 5(6)-benzene ring substituted benzimidazole-2-carbamate derivatives having anthelmintic activity
CA1020544A (en) DERIVATIVES OF 7.alpha.-METHYLESTR-4-ENE-3.alpha., 17.beta.-DIOLS
IT1011854B (it) Procedimento per la produzione del maltosio per via enzimatica
CA1034572A (en) 6-NOR-6-ALKYL-9,10-DIHYDRO-2'.beta.-METHYL-5'.alpha.-BENZYL-ERGOPEPTINE
IT8221254A0 (it) Procedimento per la preparazione di derivati del (7e,9z)-alcadienolo.
CA1032171A (en) 5(6)-benzene ring substituted benzimidazole-2-carbamate derivatives having anthelmintic activity
AU465495B2 (en) New arylpiperazine derivatives of adenine
IE39049B1 (en) New 1,4-dihydroquinoline derivatives their production and their medicinal use
CA1025448A (en) 1,3-benzodioxole derivatives
CA1018985A (en) .alpha.-ALKYL (OR ARYL) THIO-5-HYDROXYTRYPTOPHAN DERIVATIVE AND THE PREPARATION PROCESS THEREOF
CA1030536A (en) 3,9-bis-basic-ester derivatives of 7h-benz (d,e) anthracene-7-ones
JPS5651414A (en) Antibiotic substance neplanocin preparation
SU610948A1 (ru) Гидравлическа система скрепера
CA914665A (en) PREPARATION OF 17-MONOESTERS OF 17.alpha.,21-DIHYDROXY-STEROIDS
CA911998A (en) 18-METHYL-2.alpha.,3.alpha.-EPITHIO-5.alpha.-ANDROSTANE DERIVATIVES
SU681216A1 (ru) Жидкостнокольцева вакуумна установка
AU471573B2 (en) Stabilisation of 3-alkyl-1, 2, 4-oxidiazoles

Legal Events

Date Code Title Description
NAL Patent in force

Ref document number: 8201013-3

Format of ref document f/p: F

NUG Patent has lapsed

Ref document number: 8201013-3

Format of ref document f/p: F