SE8300577L - Overdrag som tillforsekrar reglerad avgivning av akriva bestandsdelar fran biologiskt aktiva blandningar, i synnerhet farmaceutiska beredningar, jemte sett att framstella biologiskt aktiva blandningar med reglerad .... - Google Patents

Overdrag som tillforsekrar reglerad avgivning av akriva bestandsdelar fran biologiskt aktiva blandningar, i synnerhet farmaceutiska beredningar, jemte sett att framstella biologiskt aktiva blandningar med reglerad ....

Info

Publication number
SE8300577L
SE8300577L SE8300577A SE8300577A SE8300577L SE 8300577 L SE8300577 L SE 8300577L SE 8300577 A SE8300577 A SE 8300577A SE 8300577 A SE8300577 A SE 8300577A SE 8300577 L SE8300577 L SE 8300577L
Authority
SE
Sweden
Prior art keywords
biologically active
regulated
water
coating
active ingredient
Prior art date
Application number
SE8300577A
Other languages
English (en)
Other versions
SE8300577D0 (sv
SE448061B (sv
Inventor
J Dobo
E Takacs
G Hortobagyi
M Skvorecz
I Kolbe
K Hoffmann
Original Assignee
Richter Gedeon Vegyeszet
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Richter Gedeon Vegyeszet filed Critical Richter Gedeon Vegyeszet
Publication of SE8300577D0 publication Critical patent/SE8300577D0/sv
Publication of SE8300577L publication Critical patent/SE8300577L/sv
Publication of SE448061B publication Critical patent/SE448061B/sv

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A61K9/2853—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyethylene oxide, poloxamers, poly(lactide-co-glycolide)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
    • A61K9/209—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat containing drug in at least two layers or in the core and in at least one outer layer
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/282—Organic compounds, e.g. fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A61K9/284—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A61K9/286—Polysaccharides, e.g. gums; Cyclodextrin
    • A61K9/2866—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
    • A61K9/5078—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings with drug-free core

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Claims (2)

PATENTKRAV
1. FOrfarande far framstallnIng av biologiskt aktiva kompositioner, i synnerhet farmaceutiskt aktiva kompositioner med kontrollerad frigoring av aktiva bestandsdelar, kannetecknat av att man belagger tabletter eller granuler innehallande den aktiva bestandsdalen med en averdragskomposition, corn innehaller ett vattenolasligt och i mag-tarmsafterna olosligt fllmbildande cellulosaderivat, faretradesv/s cellulosetriacetat eller filmbildande vinylkloridpolymer eller vinylklorid-vinylacetatsampolymer, upplost i ett med vatten joke blandbaxt orgeniskt lasningsmedel eller en blandning av dylika losningsmedel, i vilken polymerlOsning en vattenfas Sr dispexgerad f8r bildning av vatskedroppar med en diameter av upp till ,n4,, fOretrades- vis 1-5 am, varvid vaillp(asen utgar 2, faretradesvis
2. -8% av den totala vuoch vattenopparna inne- hiller 5-30% polyetylenglykol eller glycerol som mjuk- ningsmedel far polymeren och eventuellt 0,05-0,2 mol av en sur eller alkalisk buffert, och att man eventuellt p& averdraget pa i och for sig kAnt satt applicerar ett skikt, cam innehaller en ytterligare aktiv bestandsdel.
SE8300577A 1976-09-17 1983-02-03 Forfarande for framstellning av farmaceutiskt aktiva kompositioner med kontrollerad frigoring av aktiva bestandsdelar der den aktiva komponenten overdragits med en polymerlosning i vilken en vattenfas er dispergerad SE448061B (sv)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU76RI596A HU174057B (hu) 1976-09-17 1976-09-17 Sostav dlja pokrytij obespechivajuhhij uregulirovannuju otdachy aktivnogo vehhestva biologicheski aktivnykh preparatov i sposob poluchenija takikh preparatov s uregulirovannoj otdachej aktivnogo vehhestva

Publications (3)

Publication Number Publication Date
SE8300577D0 SE8300577D0 (sv) 1983-02-03
SE8300577L true SE8300577L (sv) 1983-02-03
SE448061B SE448061B (sv) 1987-01-19

Family

ID=11001002

Family Applications (2)

Application Number Title Priority Date Filing Date
SE7710360A SE440025B (sv) 1976-09-17 1977-09-15 Polymerbaserad overdragskomposition, som tillforsekrar kontrollerad frigoring av aktiva bestandsdelar samt sett att framstella denna
SE8300577A SE448061B (sv) 1976-09-17 1983-02-03 Forfarande for framstellning av farmaceutiskt aktiva kompositioner med kontrollerad frigoring av aktiva bestandsdelar der den aktiva komponenten overdragits med en polymerlosning i vilken en vattenfas er dispergerad

Family Applications Before (1)

Application Number Title Priority Date Filing Date
SE7710360A SE440025B (sv) 1976-09-17 1977-09-15 Polymerbaserad overdragskomposition, som tillforsekrar kontrollerad frigoring av aktiva bestandsdelar samt sett att framstella denna

Country Status (20)

Country Link
US (1) US4267138A (sv)
JP (1) JPS6037093B2 (sv)
AT (1) AT355726B (sv)
AU (1) AU515157B2 (sv)
BE (1) BE858797A (sv)
CA (1) CA1110166A (sv)
CH (1) CH634748A5 (sv)
DD (1) DD137669A5 (sv)
DE (1) DE2741755C2 (sv)
DK (1) DK152831C (sv)
ES (1) ES462418A1 (sv)
FI (1) FI65911C (sv)
FR (1) FR2364660A1 (sv)
GB (1) GB1593062A (sv)
HU (1) HU174057B (sv)
IL (1) IL52936A (sv)
NL (1) NL7710182A (sv)
NO (1) NO148802C (sv)
SE (2) SE440025B (sv)
SU (1) SU1158030A3 (sv)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1980000659A1 (en) * 1978-10-02 1980-04-17 Purdue Research Foundation Food and pharmaceutical coating composition,method of preparation and products so coated
CH647676A5 (fr) * 1978-12-22 1985-02-15 Donald E Panoz Formes galeniques a usage oral, a liberation programmee et leurs procedes de preparation.
FR2470599A1 (fr) * 1979-12-07 1981-06-12 Panoz Donald Perfectionnements apportes aux procedes de preparation de formes galeniques a action retard et a liberation programmee et formes galeniques de medicaments ainsi obtenus
JPS5911563B2 (ja) * 1980-02-27 1984-03-16 日本原子力研究所 多層構造の徐放性複合体を製造する方法
JPS58157711A (ja) * 1982-03-12 1983-09-19 Kuraray Co Ltd 歯面保護用塗布剤
ATE47519T1 (de) * 1982-07-08 1989-11-15 Leo Ab Tabletten mit verzoegerter freisetzung sowie verfahren zu deren herstellung.
DK151608C (da) * 1982-08-13 1988-06-20 Benzon As Alfred Fremgangsmaade til fremstilling af et farmaceutisk peroralt polydepotpraeparat med kontrolleret afgivelse
JPS59167521A (ja) * 1983-03-14 1984-09-21 Shin Etsu Chem Co Ltd 腸溶性コ−テイング剤組成物
JPS59190925A (ja) * 1983-04-12 1984-10-29 Shin Etsu Chem Co Ltd 腸溶性コ−テイング剤組成物
US4548990A (en) * 1983-08-15 1985-10-22 Ciba-Geigy Corporation Crosslinked, porous polymers for controlled drug delivery
US4587069A (en) * 1983-10-31 1986-05-06 Twinoak Products, Inc. Process for producing color display means
IT1201136B (it) * 1987-01-13 1989-01-27 Resa Farma Compressa per uso farmaceutico atta al rilascio in tempi successivi di sostanze attive
GB8707740D0 (en) * 1987-04-01 1987-05-07 Strathclyde Minerals Ltd Composition
DE3814532A1 (de) * 1988-04-29 1989-11-09 Bayer Ag Dhp-retard-zubereitung
US5612059A (en) * 1988-08-30 1997-03-18 Pfizer Inc. Use of asymmetric membranes in delivery devices
US5028433A (en) * 1988-11-30 1991-07-02 Banyu Pharmaceutical Co., Ltd. Readily absorbable drug formulation of NB-818
ATE118345T1 (de) * 1990-08-07 1995-03-15 Pfizer Verwendung von interfacial polymerisierten membranen in abgabevorrichtungen.
CA2293793C (en) * 1997-06-13 2006-07-11 American Home Products Corporation Rapamycin formulations for oral administration
CA2372994C (en) * 1999-06-04 2010-03-23 Alza Corporation Implantable gel compositions and method of manufacture
JP4644397B2 (ja) * 2001-09-05 2011-03-02 信越化学工業株式会社 難溶性薬物を含む医薬用固形製剤の製造方法

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK92805C (da) * 1959-02-18 1962-02-19 Abbott Lab Fremgangsmåde til belægning af tabletter og lignende faste medikamenter og flydende blanding til anvendelse ved fremgangsmåden.
DK93751C (da) * 1959-02-18 1962-06-25 Abbott Lab Fremgangsmåde til overtrækning af tabletter og flydende blanding til brug ved fremgangsmåden.
DK100254C (da) * 1961-06-13 1964-11-09 Abbott Lab Overtrækningsmiddel til tabletter.
US3148124A (en) * 1962-06-12 1964-09-08 William E Gaunt Method of preparing sustained release pharmaceutical tablets
FR1534254A (fr) * 1966-08-16 1968-07-26 Phytogen Products Procédé pour bloquer et favoriser l'oestrus et produit de blocage
DE1617351A1 (sv) * 1967-06-28 1972-01-05
SE324859B (sv) * 1967-09-04 1970-06-15 Ercopharm As
USRE27107E (en) 1968-05-01 1971-03-30 Drug composition
US3655129A (en) * 1968-07-17 1972-04-11 Ppg Industries Inc Slow release films and methods of making same
GB1276089A (en) * 1968-08-23 1972-06-01 Pfizer Ltd Pharmaceutical preparations
US3773919A (en) * 1969-10-23 1973-11-20 Du Pont Polylactide-drug mixtures
BE791632A (fr) * 1971-11-20 1973-05-21 Schering Ag Supports a base de caoutchouc siliconique pour agents medicamenteux
GB1425550A (en) * 1973-04-25 1976-02-18 Alza Corp Device for releasing active agent and process for producing the same
US3923939A (en) * 1974-06-07 1975-12-02 Alza Corp Process for improving release kinetics of a monolithic drug delivery device
US3946106A (en) * 1974-10-24 1976-03-23 G. D. Searle & Co. Microsealed pharmaceutical delivery device

Also Published As

Publication number Publication date
AU515157B2 (en) 1981-03-19
BE858797A (fr) 1978-01-16
SE440025B (sv) 1985-07-15
ATA665877A (de) 1979-08-15
IL52936A0 (en) 1977-11-30
CH634748A5 (de) 1983-02-28
NO148802B (no) 1983-09-12
FI772719A7 (fi) 1978-03-18
FR2364660A1 (fr) 1978-04-14
NO148802C (no) 1983-12-21
HU174057B (hu) 1979-10-28
DE2741755A1 (de) 1978-03-23
DD137669A5 (de) 1979-09-19
US4267138A (en) 1981-05-12
IL52936A (en) 1981-06-29
NO773187L (no) 1978-03-20
FI65911C (fi) 1984-08-10
ES462418A1 (es) 1978-12-01
JPS6037093B2 (ja) 1985-08-24
DE2741755C2 (de) 1986-09-25
NL7710182A (nl) 1978-03-21
SE8300577D0 (sv) 1983-02-03
JPS5362822A (en) 1978-06-05
DK152831C (da) 1988-11-07
AU2878077A (en) 1979-03-22
SE448061B (sv) 1987-01-19
FR2364660B1 (sv) 1982-12-10
CA1110166A (en) 1981-10-06
AT355726B (de) 1980-03-25
DK152831B (da) 1988-05-24
GB1593062A (en) 1981-07-15
SU1158030A3 (ru) 1985-05-23
DK409177A (da) 1978-03-18
FI65911B (fi) 1984-04-30

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