SE8304920L - Farmakologiska kompositioner baserade pa cisplatina och forfarande for framstellning derav - Google Patents

Farmakologiska kompositioner baserade pa cisplatina och forfarande for framstellning derav

Info

Publication number
SE8304920L
SE8304920L SE8304920A SE8304920A SE8304920L SE 8304920 L SE8304920 L SE 8304920L SE 8304920 A SE8304920 A SE 8304920A SE 8304920 A SE8304920 A SE 8304920A SE 8304920 L SE8304920 L SE 8304920L
Authority
SE
Sweden
Prior art keywords
freeze
cisplatinum
drying
dried
solution
Prior art date
Application number
SE8304920A
Other languages
English (en)
Other versions
SE464061B (sv
SE8304920D0 (sv
Inventor
G Battelli
D Oldani
A Rigamonti
Original Assignee
Erba Farmitalia
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Erba Farmitalia filed Critical Erba Farmitalia
Publication of SE8304920D0 publication Critical patent/SE8304920D0/sv
Publication of SE8304920L publication Critical patent/SE8304920L/sv
Publication of SE464061B publication Critical patent/SE464061B/sv

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/24—Heavy metals; Compounds thereof
    • A61K33/243—Platinum; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Inorganic Chemistry (AREA)
  • Dermatology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
SE8304920A 1982-09-23 1983-09-13 Framstaellning av stabil, frystorkad cis-platina(ii)-diammindiklorid ur en vatten-alkoholloesning SE464061B (sv)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT23396/82A IT1153974B (it) 1982-09-23 1982-09-23 Composizioni farmacologiche a base di cisplatino e metodo per il loro ottenimento

Publications (3)

Publication Number Publication Date
SE8304920D0 SE8304920D0 (sv) 1983-09-13
SE8304920L true SE8304920L (sv) 1984-03-24
SE464061B SE464061B (sv) 1991-03-04

Family

ID=11206716

Family Applications (1)

Application Number Title Priority Date Filing Date
SE8304920A SE464061B (sv) 1982-09-23 1983-09-13 Framstaellning av stabil, frystorkad cis-platina(ii)-diammindiklorid ur en vatten-alkoholloesning

Country Status (20)

Country Link
US (1) US4670262A (sv)
JP (1) JPS5978117A (sv)
AT (1) AT382077B (sv)
AU (1) AU559499B2 (sv)
BE (1) BE897761A (sv)
CA (1) CA1211372A (sv)
CH (1) CH655852A5 (sv)
DE (1) DE3333024A1 (sv)
DK (1) DK157168C (sv)
FI (1) FI78236C (sv)
FR (1) FR2533439B1 (sv)
GB (1) GB2127291B (sv)
GR (1) GR79055B (sv)
IE (1) IE56173B1 (sv)
IL (1) IL69752A (sv)
IT (1) IT1153974B (sv)
NL (1) NL8303211A (sv)
SE (1) SE464061B (sv)
SU (1) SU1424722A3 (sv)
ZA (1) ZA836904B (sv)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL8303657A (nl) * 1983-10-24 1985-05-17 Pharmachemie Bv Voor injectie geschikte, stabiele, waterige, zoutzuur bevattende oplossing van cisplatine, alsmede werkwijze ter bereiding daarvan.
IL76889A0 (en) * 1984-11-02 1986-02-28 Johnson Matthey Plc Solubilised platinum compound,method for the production thereof and pharmaceutical compositions containing the same
JPH0665648B2 (ja) * 1985-09-25 1994-08-24 塩野義製薬株式会社 白金系抗癌物質の安定な凍結真空乾燥製剤
JP2524217B2 (ja) * 1988-04-18 1996-08-14 マルハ株式会社 脳機能改善組成物、学習能力増強剤、記憶力増強剤、痴呆予防剤または痴呆治療剤
FI895340A7 (sv) * 1988-11-14 1990-05-15 Bristol Myers Squibb Co Hypertonisk cisplatin-lösning
US20030148933A1 (en) * 1990-10-01 2003-08-07 Pharma Mar S.A. Derivatives of dehydrodidemnin B
WO1994005299A1 (fr) * 1992-09-04 1994-03-17 Fuji Kagaku Kogyo Kabushiki Kaisha Compositions medicinales
FR2759293B1 (fr) * 1997-02-11 1999-04-30 Ethypharm Lab Prod Ethiques Microgranules contenant du cisplatine, procede de fabrication, preparation pharmaceutique et utilisation en polychimiotherapie ou en association avec une radiotherapie
GB9803448D0 (en) 1998-02-18 1998-04-15 Pharma Mar Sa Pharmaceutical formulation
CN1423564A (zh) * 1999-11-15 2003-06-11 法马马有限公司 癌症的aplidine治疗
UA76718C2 (uk) * 2000-06-30 2006-09-15 Фарма Мар, С.А. Протипухлинні похідні аплідину
CZ2003993A3 (cs) * 2000-10-12 2004-02-18 Pharma Mar, S. A. Léčivo pro léčení rakoviny podáváním aplidinu nebo analogu aplidinu a protektoru kosterního svalstva
JP4162491B2 (ja) 2001-01-25 2008-10-08 アメリカ合衆国 ボロン酸化合物製剤
RU2178702C1 (ru) * 2001-02-21 2002-01-27 Общество с ограниченной ответственностью "Нобель" Антираковое средство
WO2003026642A1 (en) * 2001-09-21 2003-04-03 Sumitomo Pharmaceuticals Co., Ltd. Freeze-dried pharmaceutical preparation
WO2003033013A1 (en) * 2001-10-19 2003-04-24 Pharma Mar, S.A. Use of aplidine for the treatment of pancreatic cancer
ATE406171T1 (de) * 2003-03-12 2008-09-15 Dana Farber Cancer Inst Inc Aplidine zur behandlung von multiplem myelom
WO2004080421A2 (en) * 2003-03-12 2004-09-23 Pharma Mar, S.A. Improved antitumoral treatments
DE50305909D1 (de) * 2003-10-13 2007-01-18 Salama Zoser B Pharmazeutische Zusammensetzung umfassend Oxoplatin und dessen Salze
US8436190B2 (en) * 2005-01-14 2013-05-07 Cephalon, Inc. Bendamustine pharmaceutical compositions
CN101389347B (zh) * 2006-02-28 2013-03-27 法马马有限公司 提高的抗肿瘤治疗
AU2008313627A1 (en) * 2007-10-19 2009-04-23 Pharma Mar, S.A. Improved antitumoral treatments
US20110009335A1 (en) * 2008-03-07 2011-01-13 Pharma Mar, S.A. Anticancer Treatments
AR072777A1 (es) 2008-03-26 2010-09-22 Cephalon Inc Formas solidas de clorhidrato de bendamustina
EP2326306A1 (en) 2008-09-25 2011-06-01 Cephalon, Inc. Liquid formulations of bendamustine
CN107773538B (zh) * 2016-08-27 2022-09-13 鲁南制药集团股份有限公司 稳定的甲啶铂无菌冻干粉末及其制备工艺
HRP20231233T1 (hr) 2017-04-27 2024-01-19 Pharma Mar, S.A. Antitumorski spojevi

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1432563A (en) * 1972-04-10 1976-04-22 Rustenburg Platinum Mines Ltd Platinum- co-ordination compounds
GB1432562A (en) * 1972-04-10 1976-04-22 Rustenburg Platinum Mines Ltd Platinum co-ordination compounds
US4053587A (en) * 1973-04-13 1977-10-11 Research Corporation Method of treating viral infections
US4255417A (en) * 1976-08-04 1981-03-10 Johnson Matthey, Inc. Platinum compounds for the irradication of skin blemishes
CA1119954A (en) * 1978-05-30 1982-03-16 Edmund S. Granatek Aqueous solution of cisplatin
US4273755A (en) * 1979-08-16 1981-06-16 Mpd Technology Corporation Preparation of platinum complexes
US4302446A (en) * 1979-10-02 1981-11-24 Bristol-Myers Company Pharmaceutical compositions
AU541056B2 (en) * 1980-03-31 1984-12-13 Bristol-Myers Company Pharmaceuticals formulations
US4451447A (en) * 1980-03-31 1984-05-29 Bristol-Myers Company Pharmaceutical formulations

Also Published As

Publication number Publication date
FI78236C (sv) 1989-07-10
IT1153974B (it) 1987-01-21
SU1424722A3 (ru) 1988-09-15
US4670262A (en) 1987-06-02
FI833300A0 (fi) 1983-09-15
BE897761A (fr) 1984-01-02
AU559499B2 (en) 1987-03-12
AU1908983A (en) 1984-03-29
IL69752A (en) 1986-07-31
SE464061B (sv) 1991-03-04
GB2127291B (en) 1986-01-15
IE56173B1 (en) 1991-05-08
ZA836904B (en) 1984-10-31
DK424383D0 (da) 1983-09-16
GB8324380D0 (en) 1983-10-12
DK424383A (da) 1984-03-24
IL69752A0 (en) 1983-12-30
FI833300A7 (fi) 1984-03-24
JPS5978117A (ja) 1984-05-04
ATA326283A (de) 1986-06-15
FR2533439B1 (fr) 1986-08-14
FR2533439A1 (fr) 1984-03-30
NL8303211A (nl) 1984-04-16
DE3333024A1 (de) 1984-03-29
IE832172L (en) 1984-03-23
DK157168C (da) 1990-04-09
GB2127291A (en) 1984-04-11
AT382077B (de) 1987-01-12
CH655852A5 (de) 1986-05-30
FI78236B (fi) 1989-03-31
IT8223396A0 (it) 1982-09-23
CA1211372A (en) 1986-09-16
SE8304920D0 (sv) 1983-09-13
DK157168B (da) 1989-11-20
GR79055B (sv) 1984-10-02

Similar Documents

Publication Publication Date Title
SE8304920L (sv) Farmakologiska kompositioner baserade pa cisplatina och forfarande for framstellning derav
DE3688114D1 (de) Inklusionskomplexe von 7-isopropoxy-isoflavon mit cyclodextrinen, verfahren zu deren herstellung und diese inklusionskomplexe enthaltende pharmazeutische praeparate.
ES2082755T3 (es) Derivados de acido 3-desmetil-mevalonico, procedimiento para su preparacion, preparados farmaceuticos a base de estos compuestos, su utilizacion asi como productos intermedios.
SE8300623L (sv) Farmaceutisk komposition innehallande stabil mikrokristallin cis-platina(ii)-diammindiklorid (cisplatin)
NO885213D0 (no) Stabiliserte legemidler, fremgangsmŸte til deres fremstilling samt stabile legemiddeltilberedninger.
HUT38263A (en) Process for rendering active substances soluble and production of therapeutic compositions comprising these substances
ATE101340T1 (de) Neue arzneimittelformulierung sowie verfahren zu deren herstellung.
DK280884D0 (da) Galeniske praeparatformer for orale antidiabetica og fremgangsmaade til deres fremstilling
NO164817C (no) Fremgangsmaate til fremstilling av tofasede, nifedipinholdige, legemiddeltilberedninger.
DK281184A (da) Galeniske praeparatformer for orale antidiabetica og fremgangsmaade til deres fremstilling
PT87767A (pt) Process for the manufacture of solid drug preparations containing micronized crystals of 2-phenyl-1,2-benzisoselenazol-3 (2h)-one (ebselen
IL102814A0 (en) Pyrazine derivatives,their preparation and pharmaceutical compositions comprising them
NO870560D0 (no) Fremgangsmaate for fremstilling av et farmasoeytisk preparat
NO179436C (no) Fremgangsmåte for fremstilling av farmasöytiske produkter for topisk bruk
DE3378120D1 (en) Thiazaspiro derivatives, process for their preparation and pharmaceutical composition
ATE285770T1 (de) Verfahren zur herstellung von carbapenem- antibiotika zubereitungen
NO126529B (sv)
YU83691A (sh) 3'-diamino-4'-deoksi-4'-amino-8-fluoroantraciklini i postupak za njihovu proizvodnju
ATE4808T1 (de) Piperidinderivate von 3-hydroxy-thiophen-2carbons[ureestern,ihre herstellung und diese enthaltende pharmazeutische zubereitungen.
AT342761B (de) Verfahren zur herstellung von homopyrimidazol-derivate enthaltenden, stabilen pharmazeutischen praparaten zur oralen verabreichung
HU901875D0 (en) Process for production of galenical preparations providing optimal biological accessibility of 2-hydroxi-5-methyl-laurophenon-oxim as active substance
US3159650A (en) Triethylenetetramine tetrascorbate and its preparation
Alaupovic et al. Relationship of Chemical Structure to Hemodynamic Properties of Endotoxins
DE3375077D1 (en) Galenic form of amitriptyloxide, and process for its preparation
HU172247B (hu) Sposob poluchenija sinergeticheskogo lechebnogo preparata soderzhahhego 5-ftor-citozin i kandicidin ili trikhomicin

Legal Events

Date Code Title Description
NUG Patent has lapsed

Ref document number: 8304920-5

Effective date: 19940410

Format of ref document f/p: F