SE8406202L - Framstellning av penicillansyraderivat - Google Patents

Framstellning av penicillansyraderivat

Info

Publication number: SE8406202L
Authority: SE; Sweden
Prior art keywords: compounds; beta; formula; preparation; acid derivatives
Prior art date: 1979-05-21

Application number

SE8406202A

Other languages

English (en)

Other versions

SE462097B (sv

SE8406202D0 (sv

Inventor

Daehne W Von

Original Assignee

Leo Pharm Prod Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1979-05-21

Filing date

1984-12-06

Publication date

1984-12-06

1984-12-06 Application filed by Leo Pharm Prod Ltd filed Critical Leo Pharm Prod Ltd

1984-12-06 Publication of SE8406202L publication Critical patent/SE8406202L/sv

1984-12-06 Publication of SE8406202D0 publication Critical patent/SE8406202D0/sv

1990-05-07 Publication of SE462097B publication Critical patent/SE462097B/sv

Links

RBKMMJSQKNKNEV-RITPCOANSA-N penicillanic acid Chemical class OC(=O)[C@H]1C(C)(C)S[C@@H]2CC(=O)N21 RBKMMJSQKNKNEV-RITPCOANSA-N 0.000 title abstract 2
150000001875 compounds Chemical class 0.000 abstract 4
150000002148 esters Chemical class 0.000 abstract 3
150000003839 salts Chemical class 0.000 abstract 3
239000002253 acid Substances 0.000 abstract 2
150000007513 acids Chemical class 0.000 abstract 2
238000000034 method Methods 0.000 abstract 2
241000894006 Bacteria Species 0.000 abstract 1
108020004256 Beta-lactamase Proteins 0.000 abstract 1
WKBOTKDWSSQWDR-UHFFFAOYSA-N Bromine atom Chemical compound [Br] WKBOTKDWSSQWDR-UHFFFAOYSA-N 0.000 abstract 1
ZAMOUSCENKQFHK-UHFFFAOYSA-N Chlorine atom Chemical compound [Cl] ZAMOUSCENKQFHK-UHFFFAOYSA-N 0.000 abstract 1
102000006635 beta-lactamase Human genes 0.000 abstract 1
GDTBXPJZTBHREO-UHFFFAOYSA-N bromine Substances BrBr GDTBXPJZTBHREO-UHFFFAOYSA-N 0.000 abstract 1
229910052794 bromium Inorganic materials 0.000 abstract 1
229910052801 chlorine Inorganic materials 0.000 abstract 1
239000000460 chlorine Substances 0.000 abstract 1
239000003814 drug Substances 0.000 abstract 1
239000003112 inhibitor Substances 0.000 abstract 1
PNDPGZBMCMUPRI-UHFFFAOYSA-N iodine Chemical compound II PNDPGZBMCMUPRI-UHFFFAOYSA-N 0.000 abstract 1
231100000252 nontoxic Toxicity 0.000 abstract 1
230000003000 nontoxic effect Effects 0.000 abstract 1
239000008194 pharmaceutical composition Substances 0.000 abstract 1
230000003389 potentiating effect Effects 0.000 abstract 1
238000002560 therapeutic procedure Methods 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Life Sciences & Earth Sciences (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Veterinary Medicine (AREA)
Pharmacology & Pharmacy (AREA)
Public Health (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Communicable Diseases (AREA)
Oncology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

SE8406202A 1979-05-21 1984-12-06 Foerfarande foer framstaellning av en i huvudsak ren 6 beta-halogen penicillansyra SE462097B (sv)

Applications Claiming Priority (4)

Application Number	Priority Date	Filing Date	Title
GB7917665		1979-05-21
GB7930819		1979-09-05
GB7941252		1979-11-29
GB8006681		1980-02-27

Publications (3)

Publication Number	Publication Date
SE8406202L true SE8406202L (sv)	1984-12-06
SE8406202D0 SE8406202D0 (sv)	1984-12-06
SE462097B SE462097B (sv)	1990-05-07

Family

ID=27449123

Family Applications (3)

Application Number	Title	Priority Date	Filing Date
SE8003722A SE452465B (sv)	1979-05-21	1980-05-19	6 beta-halopenicillansyraderivat och kompositioner innehallande desamma
SE8406201A SE462096B (sv)	1979-05-21	1984-12-06	Dicyklohexylammonium-6 beta-brompenicillanat vilken aer anvaendbar saasom mellanprodukt
SE8406202A SE462097B (sv)	1979-05-21	1984-12-06	Foerfarande foer framstaellning av en i huvudsak ren 6 beta-halogen penicillansyra

Family Applications Before (2)

Application Number	Title	Priority Date	Filing Date
SE8003722A SE452465B (sv)	1979-05-21	1980-05-19	6 beta-halopenicillansyraderivat och kompositioner innehallande desamma
SE8406201A SE462096B (sv)	1979-05-21	1984-12-06	Dicyklohexylammonium-6 beta-brompenicillanat vilken aer anvaendbar saasom mellanprodukt

Country Status (19)

Country	Link
US (3)	US4446144A (sv)
JP (1)	JPS55154977A (sv)
AU (3)	AU534754B2 (sv)
BE (1)	BE883390A (sv)
CA (1)	CA1265787A (sv)
DE (3)	DE3051037C2 (sv)
DK (2)	DK158669C (sv)
FI (1)	FI801618A7 (sv)
FR (2)	FR2457294A1 (sv)
GR (1)	GR68372B (sv)
IE (2)	IE49770B1 (sv)
IL (1)	IL59948A0 (sv)
IT (1)	IT1133091B (sv)
LU (1)	LU82468A1 (sv)
NL (1)	NL8002911A (sv)
NZ (1)	NZ193597A (sv)
PH (2)	PH17959A (sv)
PT (1)	PT71273A (sv)
SE (3)	SE452465B (sv)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4432970A (en) *	1979-11-23	1984-02-21	Pfizer Inc.	6-beta-Halopenicillanic acid 1,1-dioxides as beta-lactamase inhibitors
IE51846B1 (en) *	1980-11-17	1987-04-15	Leo Pharm Prod Ltd	Pharmaceutical preparation for veterinary use and an appliance containing it
US4521533A (en) *	1984-07-12	1985-06-04	Pfizer Inc.	Salts of 6-alpha-(aminomethyl)penicillanic acid 1,1-dioxide esters and beta-lactam antibiotics
GB8522156D0 (en) *	1985-09-06	1985-10-09	Leo Pharm Prod Ltd	Producing chemical compounds
US5695951A (en) *	1994-12-20	1997-12-09	Biopure Corporation	Chlorination of cephalexin with chloroperoxidase from Rathayibacter biopuresis
US5589354A (en) *	1994-12-20	1996-12-31	Biopure Corporation	Halogenation of cephalexin with haloperoxidase from Rathayibacter biopuresis
GB2334886B (en)	1996-12-18	2000-08-23	Bimeda Res Dev Ltd	Antiinfective free intramammary veterinary composition
US20020035107A1 (en) *	2000-06-20	2002-03-21	Stefan Henke	Highly concentrated stable meloxicam solutions
WO2004037265A1 (en) *	2002-10-25	2004-05-06	Akzo Nobel N.V.	Prolonged release pharmaceutical composition
EP1568369A1 (en)	2004-02-23	2005-08-31	Boehringer Ingelheim Vetmedica Gmbh	Use of meloxicam for the treatment of respiratory diseases in pigs
DE102004025324A1 (de) *	2004-05-19	2005-12-08	Boehringer Ingelheim Vetmedica Gmbh	Flüssige Zubereitung für die Veterinärmedizin, Verfahren zu deren Herstellung und deren Verwendung
EP2874623B1 (en)	2012-07-17	2018-12-12	Bayer New Zealand Limited	Injectable antibiotic formulations and their methods of use
EP2874624B8 (en) *	2012-07-17	2019-10-02	Bayer New Zealand Limited	Injectable antibiotic formulations and their methods of use
EP2934524B1 (en) *	2012-12-20	2019-03-27	Alleva Animal Health Limited	Penethamate veterinary injectable formulations
EP4265241A1 (en) *	2022-04-20	2023-10-25	Bilim Ilac Sanayii Ve Ticaret A.S.	Tablet formulations for the treatment of urinary system infections and method for the preparation of such formulations

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3206469A (en) *	1961-08-15	1965-09-14	Lepetit Spa	6-halopenicillanic acid
GB1297555A (sv) *	1970-09-22	1972-11-22
GB1377817A (en) *	1971-06-09	1974-12-18	Beecham Group Ltd	Penicillins and cephalosporins
US4234579A (en) *	1977-06-07	1980-11-18	Pfizer Inc.	Penicillanic acid 1,1-dioxides as β-lactamase inhibitors
IN149747B (sv) *	1977-06-07	1982-04-03	Pfizer
US4180506A (en) *	1978-01-18	1979-12-25	Rex Pratt	6β-Bromo penicillanic acid
CA1158639A (en)	1978-12-11	1983-12-13	Eric M. Gordon	6-bromopenicillanic acid sulfone
US4203992A (en) *	1978-12-11	1980-05-20	E. R. Squibb & Sons, Inc.	β-Bromopenicillanic acid sulfone
EP0013617B1 (en) *	1979-01-10	1984-07-04	Beecham Group Plc	Penicillin derivatives, process for their preparation and pharmaceutical compositions containing certain of these compounds
IL59081A0 (en) *	1979-01-10	1980-05-30	Schering Corp	2-penem compounds and a method for preparing them
US4518530A (en) *	1979-03-05	1985-05-21	Pfizer Inc.	6-β-Substituted penicillanic acids as β-lactamase inhibitors
US4397783A (en) *	1979-03-05	1983-08-09	Pfizer Inc.	Process for converting 6,6-disubstituted penicillanic acid derivatives to the 6-β-congeners
US4287181A (en) *	1979-10-22	1981-09-01	Pfizer Inc.	Derivatives of 6β-hydroxyalkylpenicillanic acids as β-lactamase inhibitors
US4432970A (en) *	1979-11-23	1984-02-21	Pfizer Inc.	6-beta-Halopenicillanic acid 1,1-dioxides as beta-lactamase inhibitors

1980
- 1980-04-29 IL IL59948A patent/IL59948A0/xx unknown
- 1980-04-29 IE IE2559/84A patent/IE49770B1/en unknown
- 1980-04-29 IE IE868/80A patent/IE49768B1/en not_active IP Right Cessation
- 1980-05-01 NZ NZ193597A patent/NZ193597A/en unknown
- 1980-05-05 PH PH23982A patent/PH17959A/en unknown
- 1980-05-12 GR GR61906A patent/GR68372B/el unknown
- 1980-05-19 SE SE8003722A patent/SE452465B/sv not_active IP Right Cessation
- 1980-05-20 AU AU58584/80A patent/AU534754B2/en not_active Ceased
- 1980-05-20 JP JP6768580A patent/JPS55154977A/ja active Granted
- 1980-05-20 BE BE0/200687A patent/BE883390A/fr not_active IP Right Cessation
- 1980-05-20 FR FR8011263A patent/FR2457294A1/fr active Granted
- 1980-05-20 DE DE19803051037 patent/DE3051037C2/de not_active Expired
- 1980-05-20 DE DE19803051038 patent/DE3051038C2/de not_active Expired
- 1980-05-20 PT PT71273A patent/PT71273A/pt unknown
- 1980-05-20 CA CA000352237A patent/CA1265787A/en not_active Expired - Lifetime
- 1980-05-20 IT IT67790/80A patent/IT1133091B/it active
- 1980-05-20 LU LU82468A patent/LU82468A1/fr unknown
- 1980-05-20 DE DE19803019244 patent/DE3019244A1/de active Granted
- 1980-05-20 FI FI801618A patent/FI801618A7/fi not_active Application Discontinuation
- 1980-05-20 NL NL8002911A patent/NL8002911A/nl not_active Application Discontinuation
- 1980-05-20 DK DK218580A patent/DK158669C/da not_active IP Right Cessation
- 1980-11-17 US US06/207,614 patent/US4446144A/en not_active Expired - Lifetime
1982
- 1982-03-04 FR FR8203636A patent/FR2499575A1/fr active Granted
1983
- 1983-08-26 AU AU18487/83A patent/AU541323B2/en not_active Ceased
- 1983-08-26 AU AU18486/83A patent/AU541322B2/en not_active Ceased
- 1983-08-26 PH PH29453A patent/PH19005A/en unknown
- 1983-12-23 US US06/564,901 patent/US4594246A/en not_active Expired - Fee Related
1984
- 1984-12-06 SE SE8406201A patent/SE462096B/sv not_active IP Right Cessation
- 1984-12-06 SE SE8406202A patent/SE462097B/sv not_active IP Right Cessation
1986
- 1986-03-31 US US06/845,941 patent/US4672114A/en not_active Expired - Fee Related
1989
- 1989-11-10 DK DK562589A patent/DK158670C/da not_active IP Right Cessation

Also Published As

Publication number	Publication date
AU5858480A (en)	1980-11-27
AU534754B2 (en)	1984-02-16
FR2457294A1 (fr)	1980-12-19
JPH0140837B2 (sv)	1989-08-31
BE883390A (fr)	1980-11-20
GR68372B (sv)	1981-12-28
SE462097B (sv)	1990-05-07
NZ193597A (en)	1985-04-30
US4446144A (en)	1984-05-01
AU1848783A (en)	1983-12-22
PH17959A (en)	1985-02-20
DK158670B (da)	1990-07-02
SE8406202D0 (sv)	1984-12-06
US4672114A (en)	1987-06-09
IE49770B1 (en)	1985-12-11
IE842559L (en)	1980-11-21
SE8406201L (sv)	1984-12-06
DK158669B (da)	1990-07-02
AU541322B2 (en)	1985-01-03
CA1265787A (en)	1990-02-13
FR2499575B1 (sv)	1985-03-01
AU541323B2 (en)	1985-01-03
JPS55154977A (en)	1980-12-02
SE462096B (sv)	1990-05-07
LU82468A1 (fr)	1980-12-16
NL8002911A (nl)	1980-11-25
DK218580A (da)	1980-11-22
IL59948A0 (en)	1980-06-30
SE8406201D0 (sv)	1984-12-06
DK562589A (da)	1989-11-10
AU1848683A (en)	1983-12-22
FI801618A7 (fi)	1981-01-01
DE3051038A1 (sv)	1986-03-20
FR2499575A1 (fr)	1982-08-13
DE3019244C2 (sv)	1989-04-06
DE3051038C2 (sv)	1989-04-13
PT71273A (en)	1980-06-01
US4594246A (en)	1986-06-10
DE3051037C2 (sv)	1989-03-30
SE8003722L (sv)	1980-11-22
DK562589D0 (da)	1989-11-10
SE452465B (sv)	1987-11-30
DE3019244A1 (de)	1980-12-04
PH19005A (en)	1985-12-03
DK158670C (da)	1991-01-07
FR2457294B1 (sv)	1984-01-13
IE800868L (en)	1980-11-21
DK158669C (da)	1991-01-21
IT8067790A0 (it)	1980-05-20
IE49768B1 (en)	1985-12-11
IT1133091B (it)	1986-07-09

Legal Events

Date

Code

Title

Description

1995-01-31

NAL

Patent in force

Ref document number: 8406202-5

Format of ref document f/p: F

1996-02-05

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Patent has lapsed