SE8701700L - Nya ergolenderivat, farmaceutiska kompositioner innehallande dessa samt forfarande for framstellning derav - Google Patents

Nya ergolenderivat, farmaceutiska kompositioner innehallande dessa samt forfarande for framstellning derav

Info

Publication number: SE8701700L
Authority: SE; Sweden
Prior art keywords: stands; group; acyl; pharmaceutical compositions; compositions containing
Prior art date: 1986-04-25

Application number

SE8701700A

Other languages

English (en)

Other versions

SE466401B (sv

SE8701700D0 (sv

Inventor

T Keve

G Megyeri

B Stefko

Jr L Kovacs

A Kassai

B Kiss

I Laszlovszky

E Lapis

E Palosi

D Groo

L Szporny

Original Assignee

Richter Gedeon Vegyeszet

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1986-04-25

Filing date

1987-04-24

Publication date

1987-10-26

1987-04-24 Application filed by Richter Gedeon Vegyeszet filed Critical Richter Gedeon Vegyeszet

1987-04-24 Publication of SE8701700D0 publication Critical patent/SE8701700D0/sv

1987-10-26 Publication of SE8701700L publication Critical patent/SE8701700L/sv

1992-02-10 Publication of SE466401B publication Critical patent/SE466401B/sv

Links

238000000034 method Methods 0.000 title abstract 2
239000008194 pharmaceutical composition Substances 0.000 title abstract 2
125000002252 acyl group Chemical group 0.000 abstract 6
229910052736 halogen Inorganic materials 0.000 abstract 3
150000002367 halogens Chemical class 0.000 abstract 3
125000004178 (C1-C4) alkyl group Chemical group 0.000 abstract 1
UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
239000002253 acid Substances 0.000 abstract 1
230000000141 anti-hypoxic effect Effects 0.000 abstract 1
230000000561 anti-psychotic effect Effects 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
229910052739 hydrogen Inorganic materials 0.000 abstract 1
239000001257 hydrogen Substances 0.000 abstract 1
125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D457/00—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid
- C07D457/02—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid with hydrocarbon or substituted hydrocarbon radicals, attached in position 8
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Medicinal Chemistry (AREA)
Public Health (AREA)
Life Sciences & Earth Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Veterinary Medicine (AREA)
General Chemical & Material Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Heart & Thoracic Surgery (AREA)
Cardiology (AREA)
Psychiatry (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)

SE8701700A 1986-04-25 1987-04-24 Nya ergolenderivat, farmaceutiska kompositioner innehaallande dessa samt foerfarande foer framstaellning daerav SE466401B (sv)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
HU861719A HU196598B (en)	1986-04-25	1986-04-25	Process for producing 1- and/or 8-substituted 2-halogenated ergoline derivatives and pharmaceutics comprising such compounds

Publications (3)

Publication Number	Publication Date
SE8701700D0 SE8701700D0 (sv)	1987-04-24
SE8701700L true SE8701700L (sv)	1987-10-26
SE466401B SE466401B (sv)	1992-02-10

Family

ID=10955843

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
SE8701700A SE466401B (sv)	1986-04-25	1987-04-24	Nya ergolenderivat, farmaceutiska kompositioner innehaallande dessa samt foerfarande foer framstaellning daerav

Country Status (30)

Country	Link
US (1)	US4859682A (sv)
JP (1)	JPS62258379A (sv)
KR (1)	KR920008167B1 (sv)
CN (1)	CN87102944A (sv)
AT (1)	AT391472B (sv)
AU (1)	AU592637B2 (sv)
BE (1)	BE1001159A4 (sv)
CH (1)	CH669791A5 (sv)
CS (1)	CS268534B2 (sv)
DD (1)	DD256133A5 (sv)
DE (1)	DE3713768A1 (sv)
DK (1)	DK208887A (sv)
EG (1)	EG18272A (sv)
ES (1)	ES2007339A6 (sv)
FI (1)	FI871128A7 (sv)
FR (1)	FR2597869B1 (sv)
GB (1)	GB2189487B (sv)
GR (1)	GR870645B (sv)
HU (1)	HU196598B (sv)
IL (1)	IL82324A0 (sv)
IN (1)	IN165245B (sv)
IT (1)	IT1203976B (sv)
LU (1)	LU86853A1 (sv)
NL (1)	NL8700966A (sv)
NO (1)	NO165800C (sv)
PL (1)	PL152619B1 (sv)
PT (1)	PT84739B (sv)
SE (1)	SE466401B (sv)
SU (1)	SU1500161A3 (sv)
ZA (1)	ZA872931B (sv)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
HU196394B (en) *	1986-06-27	1988-11-28	Richter Gedeon Vegyeszet	Process for preparing 2-halogenated ergoline derivatives
US20040019093A1 (en) *	2002-04-30	2004-01-29	Judith Aronhime	Novel crystal forms of ondansetron, processes for their preparation, pharmaceutical compositions containing the novel forms and methods for treating nausea using them
US20240343692A1 (en) *	2021-08-09	2024-10-17	University Of Pittsburgh - Of The Commonwealth System Of Higher Education	Selective psychedelic compounds

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE237837C (sv) *
DE1936410A1 (de) *	1969-07-17	1971-02-11	Hoechst Ag	O-Acyl-lysergole und Verfahren zu ihrer Herstellung
AR206772A1 (es) *	1972-07-21	1976-08-23	Lilly Co Eli	Procedimiento para preparar una nueva d-2-halo-6-metil-8-ciano(carboxamido)metil ergolina
US3992385A (en) *	1975-01-20	1976-11-16	Eli Lilly And Company	2,3-Dihydroergolines
CH619709A5 (en) *	1975-03-14	1980-10-15	Siphar Sa	Process for the preparation of carbamates of 2-halogenoergolines and 2-halogenoergolenes
DE2656344A1 (de) *	1975-12-23	1977-07-07	Sandoz Ag	Ergolinderivate, ihre verwendung und herstellung
US4035094A (en) *	1976-03-11	1977-07-12	Trw Inc.	Ball and socket joint
DK75177A (da) *	1976-04-27	1977-10-28	Sandoz Ag	Fremgangsmade til fremstilling af prostaglandiner
US4098790A (en) *	1976-09-15	1978-07-04	Eli Lilly And Company	Ergoline chlorination process
DE3001752A1 (de) *	1980-01-16	1981-07-30	Schering Ag Berlin Und Bergkamen, 1000 Berlin	Verfahren zur herstellung von 8(alpha)-substituierten 6-methylergolinen
DE3151912A1 (de) *	1981-12-23	1983-06-30	Schering Ag, 1000 Berlin Und 4619 Bergkamen	Neue ergolin-aminoderivate, verfahren zu ihrer herstellung und deren verwendung als arzneimittel
DD237837A1 (de) *	1983-11-29	1986-07-30	1086 Berlin,Otto-Nuscke-Str. 2/23,Dd	Verfahren zur herstellung von 2-bromergolinen
DE3403067A1 (de) *	1984-01-30	1985-08-14	Eckart Prof. Dr. 6500 Mainz Eich	Ergolin-derivate, verfahren zu ihrer herstellung, sie enthaltende arzneimittel und deren verwendung
DE3413657A1 (de) *	1984-04-09	1985-10-17	Schering AG, 1000 Berlin und 4709 Bergkamen	Neue ergoline
HU193781B (en) *	1985-06-21	1987-11-30	Richter Gedeon Vegyeszet	Process for producing 10alpha-methoxy-6-methylergoline derivatives and acid additional salts thereof
US4782152A (en) *	1985-08-16	1988-11-01	Eli Lilly And Company	Decyanation of pergolide intermediate
HU196394B (en) *	1986-06-27	1988-11-28	Richter Gedeon Vegyeszet	Process for preparing 2-halogenated ergoline derivatives

1986
- 1986-04-25 HU HU861719A patent/HU196598B/hu not_active IP Right Cessation
1987
- 1987-03-13 FI FI871128A patent/FI871128A7/fi not_active Application Discontinuation
- 1987-04-21 US US07/040,938 patent/US4859682A/en not_active Expired - Fee Related
- 1987-04-22 PT PT84739A patent/PT84739B/pt not_active IP Right Cessation
- 1987-04-23 CN CN87102944A patent/CN87102944A/zh active Pending
- 1987-04-23 EG EG238/87A patent/EG18272A/xx active
- 1987-04-24 DK DK208887A patent/DK208887A/da not_active Application Discontinuation
- 1987-04-24 IL IL82324A patent/IL82324A0/xx not_active IP Right Cessation
- 1987-04-24 BE BE8700445A patent/BE1001159A4/fr not_active IP Right Cessation
- 1987-04-24 FR FR878705838A patent/FR2597869B1/fr not_active Expired - Lifetime
- 1987-04-24 SU SU874202410A patent/SU1500161A3/ru active
- 1987-04-24 SE SE8701700A patent/SE466401B/sv not_active IP Right Cessation
- 1987-04-24 DE DE19873713768 patent/DE3713768A1/de not_active Withdrawn
- 1987-04-24 NL NL8700966A patent/NL8700966A/nl not_active Application Discontinuation
- 1987-04-24 CS CS872920A patent/CS268534B2/cs unknown
- 1987-04-24 PL PL1987265357A patent/PL152619B1/pl unknown
- 1987-04-24 ZA ZA872931A patent/ZA872931B/xx unknown
- 1987-04-24 LU LU86853A patent/LU86853A1/de unknown
- 1987-04-24 ES ES8701211A patent/ES2007339A6/es not_active Expired
- 1987-04-24 IT IT20271/87A patent/IT1203976B/it active
- 1987-04-24 GR GR870645A patent/GR870645B/el unknown
- 1987-04-24 IN IN326/CAL/87A patent/IN165245B/en unknown
- 1987-04-24 KR KR1019870003970A patent/KR920008167B1/ko not_active Expired
- 1987-04-24 CH CH1577/87A patent/CH669791A5/de not_active IP Right Cessation
- 1987-04-24 DD DD87302104A patent/DD256133A5/de not_active IP Right Cessation
- 1987-04-24 AT AT0102287A patent/AT391472B/de active
- 1987-04-24 AU AU71945/87A patent/AU592637B2/en not_active Ceased
- 1987-04-24 JP JP62100224A patent/JPS62258379A/ja active Granted
- 1987-04-24 NO NO871721A patent/NO165800C/no unknown
- 1987-04-27 GB GB8709893A patent/GB2189487B/en not_active Expired - Lifetime

Also Published As

Publication number	Publication date
KR870010051A (ko)	1987-11-30
NO871721D0 (no)	1987-04-24
SE466401B (sv)	1992-02-10
HU196598B (en)	1988-12-28
DD256133A5 (de)	1988-04-27
FI871128A0 (fi)	1987-03-13
IL82324A0 (en)	1987-10-30
ZA872931B (sv)	1987-10-19
GB8709893D0 (en)	1987-06-03
PT84739A (en)	1987-05-01
KR920008167B1 (ko)	1992-09-24
FR2597869A1 (fr)	1987-10-30
NO165800B (no)	1991-01-02
NO165800C (no)	1991-04-10
AT391472B (de)	1990-10-10
ATA102287A (de)	1990-04-15
FI871128A7 (fi)	1987-10-26
DK208887D0 (da)	1987-04-24
US4859682A (en)	1989-08-22
CH669791A5 (sv)	1989-04-14
BE1001159A4 (fr)	1989-08-01
JPH0462316B2 (sv)	1992-10-05
IT1203976B (it)	1989-02-23
CN87102944A (zh)	1987-11-25
JPS62258379A (ja)	1987-11-10
CS268534B2 (en)	1990-03-14
NO871721L (no)	1987-10-26
CS292087A2 (en)	1989-06-13
GB2189487B (en)	1990-05-23
SE8701700D0 (sv)	1987-04-24
PL152619B1 (en)	1991-01-31
GB2189487A (en)	1987-10-28
PL265357A1 (en)	1988-07-21
PT84739B (pt)	1989-12-29
FR2597869B1 (fr)	1991-04-26
GR870645B (en)	1987-08-28
IN165245B (sv)	1989-09-09
NL8700966A (nl)	1987-11-16
AU592637B2 (en)	1990-01-18
DE3713768A1 (de)	1987-10-29
AU7194587A (en)	1987-10-29
SU1500161A3 (ru)	1989-08-07
LU86853A1 (de)	1987-08-12
ES2007339A6 (es)	1989-06-16
IT8720271A0 (it)	1987-04-24
EG18272A (en)	1993-04-30
DK208887A (da)	1987-10-26

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Legal Events

Date

Code

Title

Description

1995-01-31

NUG

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