SE8902603D0 - (rs)-2-(2,3-dihydro-5-hydroxi-4,6,7-trimetylbensofuranyl) aettiksyror och 2-(2,3-dihydro-5-acyloxi-4,6,7-trimetylbensofuranyl) aettiksyror och estrar daerav, anvaendbara saasom slemreglerande och antiischemiska laekemedeloch foerfarande foer framstaellning daerav - Google Patents

(rs)-2-(2,3-dihydro-5-hydroxi-4,6,7-trimetylbensofuranyl) aettiksyror och 2-(2,3-dihydro-5-acyloxi-4,6,7-trimetylbensofuranyl) aettiksyror och estrar daerav, anvaendbara saasom slemreglerande och antiischemiska laekemedeloch foerfarande foer framstaellning daerav

Info

Publication number: SE8902603D0
Authority: SE; Sweden
Prior art keywords: dihydro; benzofuranyl; trimethyl; acetic acids; hydroxy
Prior art date: 1988-08-01

Application number

SE8902603A

Other languages

English (en)

Other versions

SE469652B (sv

SE8902603L (sv

Inventor

M Brufani

Original Assignee

Foscama Biomed Chim Farma

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1988-08-01

Filing date

1989-07-26

Publication date

1989-07-26

1989-07-26 Application filed by Foscama Biomed Chim Farma filed Critical Foscama Biomed Chim Farma

1989-07-26 Publication of SE8902603D0 publication Critical patent/SE8902603D0/sv

1990-02-02 Publication of SE8902603L publication Critical patent/SE8902603L/sv

1993-08-16 Publication of SE469652B publication Critical patent/SE469652B/sv

Links

150000001243 acetic acids Chemical class 0.000 title abstract 3
-1 2,3-DIHYDRO-5-HYDROXY-4,6,7-TRIMETHYL BENZOFURANYL Chemical class 0.000 title 2
239000000126 substance Substances 0.000 title 1
FUWYMDOAFXKROW-UHFFFAOYSA-N 2-(5-hydroxy-4,6,7-trimethyl-2,3-dihydro-1-benzofuran-2-yl)acetic acid Chemical class CC1=C(O)C(C)=C2CC(CC(O)=O)OC2=C1C FUWYMDOAFXKROW-UHFFFAOYSA-N 0.000 abstract 1
235000011054 acetic acid Nutrition 0.000 abstract 1
230000002253 anti-ischaemic effect Effects 0.000 abstract 1
239000003795 chemical substances by application Substances 0.000 abstract 1
150000002148 esters Chemical class 0.000 abstract 1
235000019439 ethyl acetate Nutrition 0.000 abstract 1
230000001225 therapeutic effect Effects 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
- C07D307/79—Benzo [b] furans; Hydrogenated benzo [b] furans with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
- C07D307/80—Radicals substituted by oxygen atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
- C07D307/79—Benzo [b] furans; Hydrogenated benzo [b] furans with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/10—Expectorants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Rheumatology (AREA)
Pain & Pain Management (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Pulmonology (AREA)
Epidemiology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Furan Compounds (AREA)
Plural Heterocyclic Compounds (AREA)

SE8902603A 1988-08-01 1989-07-26 (rs)-2-(2,3-dihydro-5-hydroxi-4,6,7-trimetylbensofuranyl) aettiksyror och 2-(2,3-dihydro-5-acyloxi-4,6,7- trimetylbensofuranyl) aettiksyror och estrar daerav, anvaendbara saasom slemreglerande och antiischemiska laekemedel och foerfarande foer framstaellning daerav SE469652B (sv)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
IT8821603A IT1229482B (it)	1988-08-01	1988-08-01	Acidi (rs) 2 (2,3 diidro 5 idrossi 4,6,7 trimetilbenzofuranil) acetico e 2 (2,3 diidro 5 acilossi 4,6,7 trimetilbenzofuranil) acetici e loro esteri, utili come farmaci mucoregolatori ed antiischemici.

Publications (3)

Publication Number	Publication Date
SE8902603D0 true SE8902603D0 (sv)	1989-07-26
SE8902603L SE8902603L (sv)	1990-02-02
SE469652B SE469652B (sv)	1993-08-16

Family

ID=11184201

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
SE8902603A SE469652B (sv)	1988-08-01	1989-07-26	(rs)-2-(2,3-dihydro-5-hydroxi-4,6,7-trimetylbensofuranyl) aettiksyror och 2-(2,3-dihydro-5-acyloxi-4,6,7- trimetylbensofuranyl) aettiksyror och estrar daerav, anvaendbara saasom slemreglerande och antiischemiska laekemedel och foerfarande foer framstaellning daerav

Country Status (15)

Country	Link
US (2)	US4999350A (sv)
JP (1)	JPH0278675A (sv)
KR (1)	KR0129526B1 (sv)
CN (1)	CN1034574C (sv)
BE (1)	BE1003255A5 (sv)
CA (1)	CA1324134C (sv)
CH (1)	CH679583A5 (sv)
DE (1)	DE3925496A1 (sv)
ES (1)	ES2014188A6 (sv)
FR (1)	FR2634766A1 (sv)
GB (1)	GB2221463B (sv)
HK (1)	HK48693A (sv)
IT (1)	IT1229482B (sv)
SE (1)	SE469652B (sv)
SG (1)	SG26693G (sv)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
IT1231341B (it) *	1989-08-18	1991-11-28	Foscama Biomed Chim Farma	2,3 diidro 5 ossi 4,6,7 trimetilbenzofurani 2 (rs) sostituiti, utili come farmaci antiossidanti con proprieta' mucoregolatrici e antiischemiche.
IT1239946B (it) *	1990-03-12	1993-11-27	Biomedica Foscama Industria Chimicofarmaceutica	Procedimento per la sintesi degli acidi 5-acilossi e 5-alcossi-2,3-diidro-4,6,7-trimetil-2-(rs)-benzofuranacetici
US5240956A (en) *	1990-11-07	1993-08-31	Cortech, Inc.	Ester inhibitors
EP0550292A1 (en) *	1992-01-02	1993-07-07	Merrell Dow Pharmaceuticals Inc.	Tissue protective tocopherol analogs
AU670433B2 (en) *	1992-04-06	1996-07-18	Merrell Dow Pharmaceuticals Inc.	Novel derivatives of 2,3-dihydro-benzofuranols
US5721233A (en) *	1992-04-06	1998-02-24	Merrell Pharmaceuticals Inc.	Derivatives of 2,3-dihydro benzofuranols
US5510373A (en) *	1992-04-06	1996-04-23	Merrell Pharmaceuticals Inc.	Cardioprotective agents
TW393475B (en) *	1992-10-16	2000-06-11	Chugai Pharmaceutical Co Ltd	4-alkoxyl-2,6-di-t-butyl phenol derivatives
IT1289494B1 (it) *	1996-12-20	1998-10-15	Biomedica Foscana Ind Chimico	Acidi 5-idrossi- e 5-acilossi-2,3-diidro-4,6,7-trimetil-2- benzofuranaceti e loro esteri per il trattamento e la prevenzione
IT1320131B1 (it) *	2000-12-21	2003-11-18	Foscama Biomed Chim Farma	Uso degli acidi 5-idrossi e 5-acilossi-2,3-diidro-4,6,7-trimetil-2-benzofuranacetici e loro esteri come cicatrizzanti delle lesioni

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JPS6065063A (ja) *	1983-09-20	1985-04-13	Matsunaga Kagaku Kogyo Kk	難燃化剤
US4537903A (en) *	1983-10-12	1985-08-27	Merck & Co., Inc.	Substituted cinnamyl-2,3-dihydrobenzofuran and analogs useful as anti-inflammatory agents
US4918092A (en) *	1983-12-21	1990-04-17	Merck Frosst Canada, Inc.	Leukotriene antagonists
CA1281325C (en) *	1984-06-20	1991-03-12	Patrice C. Belanger	Benzofuran derivatives
JPS6388173A (ja) *	1986-09-30	1988-04-19	Kuraray Co Ltd	２，３−ジヒドロベンゾフラン誘導体
EP0273647B1 (en) *	1986-12-27	1992-03-11	Takeda Chemical Industries, Ltd.	Coumaran derivatives, their production and use
JP2855340B2 (ja) *	1988-06-10	1999-02-10	武田薬品工業株式会社	２―置換クマラン誘導体

1988
- 1988-08-01 IT IT8821603A patent/IT1229482B/it active
1989
- 1989-04-13 US US07/337,358 patent/US4999350A/en not_active Expired - Lifetime
- 1989-07-24 CH CH2760/89A patent/CH679583A5/it not_active IP Right Cessation
- 1989-07-26 SE SE8902603A patent/SE469652B/sv not_active IP Right Cessation
- 1989-07-31 JP JP1200164A patent/JPH0278675A/ja active Pending
- 1989-07-31 CA CA000607022A patent/CA1324134C/en not_active Expired - Fee Related
- 1989-08-01 FR FR8910354A patent/FR2634766A1/fr active Granted
- 1989-08-01 DE DE3925496A patent/DE3925496A1/de active Granted
- 1989-08-01 BE BE8900822A patent/BE1003255A5/fr not_active IP Right Cessation
- 1989-08-01 CN CN89107028A patent/CN1034574C/zh not_active Expired - Fee Related
- 1989-08-01 ES ES8902723A patent/ES2014188A6/es not_active Expired - Lifetime
- 1989-08-01 GB GB8917515A patent/GB2221463B/en not_active Expired - Lifetime
- 1989-08-01 KR KR1019890011057A patent/KR0129526B1/ko not_active Expired - Fee Related
1990
- 1990-09-17 US US07/583,810 patent/US5041568A/en not_active Expired - Fee Related
1993
- 1993-03-11 SG SG266/93A patent/SG26693G/en unknown
- 1993-05-20 HK HK486/93A patent/HK48693A/xx not_active IP Right Cessation

Also Published As

Publication number	Publication date
DE3925496C2 (sv)	1992-04-30
HK48693A (en)	1993-05-27
CN1034574C (zh)	1997-04-16
GB8917515D0 (en)	1989-09-13
IT8821603A0 (it)	1988-08-01
SE469652B (sv)	1993-08-16
CH679583A5 (sv)	1992-03-13
FR2634766A1 (fr)	1990-02-02
JPH0278675A (ja)	1990-03-19
GB2221463B (en)	1992-03-25
ES2014188A6 (es)	1990-06-16
CA1324134C (en)	1993-11-09
GB2221463A (en)	1990-02-07
KR0129526B1 (ko)	1998-04-09
SG26693G (en)	1993-05-21
CN1042354A (zh)	1990-05-23
DE3925496A1 (de)	1990-02-22
FR2634766B1 (sv)	1994-08-19
SE8902603L (sv)	1990-02-02
US5041568A (en)	1991-08-20
US4999350A (en)	1991-03-12
IT1229482B (it)	1991-09-03
KR900003145A (ko)	1990-03-23
BE1003255A5 (fr)	1992-02-11

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