SE8904064D0 - Improved method of preparing an intermediate for the manufacture of bambuterol - Google Patents

Improved method of preparing an intermediate for the manufacture of bambuterol

Info

Publication number: SE8904064D0
Authority: SE; Sweden
Prior art keywords: pct; bambuterol; improved method; dimethylcarbamoyloxy; acetophenone
Prior art date: 1989-12-01

Application number

SE8904064A

Other languages

English (en)

Swedish (sv)

Inventor

P Jaksch

Original Assignee

Astra Ab

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1989-12-01

Filing date

1989-12-01

Publication date

1989-12-01

1989-12-01 Application filed by Astra Ab filed Critical Astra Ab

1989-12-01 Priority to SE8904064A priority Critical patent/SE8904064D0/xx

1989-12-01 Publication of SE8904064D0 publication Critical patent/SE8904064D0/xx

1990-11-20 Priority to US07/741,424 priority patent/US5200551A/en

1990-11-26 Priority to IE424790A priority patent/IE65994B1/en

1990-11-29 Priority to DK91900394.7T priority patent/DK0456799T3/da

1990-11-29 Priority to AU68981/91A priority patent/AU630013B2/en

1990-11-29 Priority to JP3501014A priority patent/JPH04503218A/ja

1990-11-29 Priority to PCT/SE1990/000792 priority patent/WO1991008197A1/en

1990-11-29 Priority to CA002045554A priority patent/CA2045554A1/en

1990-11-29 Priority to ES91900394T priority patent/ES2054483T3/es

1990-11-29 Priority to DE69009461T priority patent/DE69009461T2/de

1990-11-29 Priority to EP91900394A priority patent/EP0456799B1/en

1990-11-29 Priority to AT91900394T priority patent/ATE106388T1/de

1990-11-30 Priority to PT96051A priority patent/PT96051B/pt

1991-07-19 Priority to NO912853A priority patent/NO174804B/no

Links

ANZXOIAKUNOVQU-UHFFFAOYSA-N bambuterol Chemical compound CN(C)C(=O)OC1=CC(OC(=O)N(C)C)=CC(C(O)CNC(C)(C)C)=C1 ANZXOIAKUNOVQU-UHFFFAOYSA-N 0.000 title abstract 2
229960003060 bambuterol Drugs 0.000 title abstract 2
238000000034 method Methods 0.000 title abstract 2
238000004519 manufacturing process Methods 0.000 title 1
XEKOWRVHYACXOJ-UHFFFAOYSA-N Ethyl acetate Chemical compound CCOC(C)=O XEKOWRVHYACXOJ-UHFFFAOYSA-N 0.000 abstract 6
KWOLFJPFCHCOCG-UHFFFAOYSA-N Acetophenone Chemical compound CC(=O)C1=CC=CC=C1 KWOLFJPFCHCOCG-UHFFFAOYSA-N 0.000 abstract 4
ZWEHNKRNPOVVGH-UHFFFAOYSA-N 2-Butanone Chemical compound CCC(C)=O ZWEHNKRNPOVVGH-UHFFFAOYSA-N 0.000 abstract 2
CPELXLSAUQHCOX-UHFFFAOYSA-N Hydrogen bromide Chemical compound Br CPELXLSAUQHCOX-UHFFFAOYSA-N 0.000 abstract 2
JUJWROOIHBZHMG-UHFFFAOYSA-N Pyridine Chemical compound C1=CC=NC=C1 JUJWROOIHBZHMG-UHFFFAOYSA-N 0.000 abstract 2
BWHMMNNQKKPAPP-UHFFFAOYSA-L potassium carbonate Chemical compound [K+].[K+].[O-]C([O-])=O BWHMMNNQKKPAPP-UHFFFAOYSA-L 0.000 abstract 2
239000002904 solvent Substances 0.000 abstract 2
WQXWIKCZNIGMAP-UHFFFAOYSA-N 3',5'-Dihydroxyacetophenone Chemical compound CC(=O)C1=CC(O)=CC(O)=C1 WQXWIKCZNIGMAP-UHFFFAOYSA-N 0.000 abstract 1
WKBOTKDWSSQWDR-UHFFFAOYSA-N Bromine atom Chemical compound [Br] WKBOTKDWSSQWDR-UHFFFAOYSA-N 0.000 abstract 1
DKPFZGUDAPQIHT-UHFFFAOYSA-N Butyl acetate Natural products CCCCOC(C)=O DKPFZGUDAPQIHT-UHFFFAOYSA-N 0.000 abstract 1
YIIMEMSDCNDGTB-UHFFFAOYSA-N Dimethylcarbamoyl chloride Chemical compound CN(C)C(Cl)=O YIIMEMSDCNDGTB-UHFFFAOYSA-N 0.000 abstract 1
NTIZESTWPVYFNL-UHFFFAOYSA-N Methyl isobutyl ketone Chemical compound CC(C)CC(C)=O NTIZESTWPVYFNL-UHFFFAOYSA-N 0.000 abstract 1
UIHCLUNTQKBZGK-UHFFFAOYSA-N Methyl isobutyl ketone Natural products CCC(C)C(C)=O UIHCLUNTQKBZGK-UHFFFAOYSA-N 0.000 abstract 1
GDTBXPJZTBHREO-UHFFFAOYSA-N bromine Substances BrBr GDTBXPJZTBHREO-UHFFFAOYSA-N 0.000 abstract 1
229910052794 bromium Inorganic materials 0.000 abstract 1
229940043232 butyl acetate Drugs 0.000 abstract 1
239000003054 catalyst Substances 0.000 abstract 1
239000013078 crystal Substances 0.000 abstract 1
229940093499 ethyl acetate Drugs 0.000 abstract 1
FUZZWVXGSFPDMH-UHFFFAOYSA-N hexanoic acid Chemical compound CCCCCC(O)=O FUZZWVXGSFPDMH-UHFFFAOYSA-N 0.000 abstract 1
229910000042 hydrogen bromide Inorganic materials 0.000 abstract 1
JMMWKPVZQRWMSS-UHFFFAOYSA-N isopropanol acetate Natural products CC(C)OC(C)=O JMMWKPVZQRWMSS-UHFFFAOYSA-N 0.000 abstract 1
229940011051 isopropyl acetate Drugs 0.000 abstract 1
GWYFCOCPABKNJV-UHFFFAOYSA-N isovaleric acid Chemical compound CC(C)CC(O)=O GWYFCOCPABKNJV-UHFFFAOYSA-N 0.000 abstract 1
229910000027 potassium carbonate Inorganic materials 0.000 abstract 1
UMJSCPRVCHMLSP-UHFFFAOYSA-N pyridine Natural products COC1=CC=CN=C1 UMJSCPRVCHMLSP-UHFFFAOYSA-N 0.000 abstract 1
238000010791 quenching Methods 0.000 abstract 1
230000000171 quenching effect Effects 0.000 abstract 1
XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C269/00—Preparation of derivatives of carbamic acid, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
- C07C269/04—Preparation of derivatives of carbamic acid, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups from amines with formation of carbamate groups

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Steroid Compounds (AREA)
Fats And Perfumes (AREA)

SE8904064A 1989-12-01 1989-12-01 Improved method of preparing an intermediate for the manufacture of bambuterol SE8904064D0 (sv)

Priority Applications (14)

Application Number	Priority Date	Filing Date	Title
SE8904064A SE8904064D0 (sv)	1989-12-01	1989-12-01	Improved method of preparing an intermediate for the manufacture of bambuterol
US07/741,424 US5200551A (en)	1989-12-01	1990-11-20	Method of preparing an intermediate for the manufacture of bambuterol
IE424790A IE65994B1 (en)	1989-12-01	1990-11-26	Improved method of preparing an intermediate for the manufacture of bambuterol
AT91900394T ATE106388T1 (de)	1989-12-01	1990-11-29	Verbesserte methode zur herstellung von einem zwischenprodukt zur bereitung von bambuterol.
PCT/SE1990/000792 WO1991008197A1 (en)	1989-12-01	1990-11-29	Improved method of preparing an intermediate for the manufacture of bambuterol
AU68981/91A AU630013B2 (en)	1989-12-01	1990-11-29	Improved method of preparing an intermediate for the manufacture of bambuterol
JP3501014A JPH04503218A (ja)	1989-12-01	1990-11-29	バンブテロール製造のための中間体の改良された製造法
DK91900394.7T DK0456799T3 (da)	1989-12-01	1990-11-29	Forbedret fremgangsmåde til fremstilling af et mellemprodukt til fremstilling af bambuterol
CA002045554A CA2045554A1 (en)	1989-12-01	1990-11-29	Method of preparing an intermediate for the manufacture of bambuterol
ES91900394T ES2054483T3 (es)	1989-12-01	1990-11-29	Metodo mejorado para preparar un producto intermedio para la fabricacion de bambuterol.
DE69009461T DE69009461T2 (de)	1989-12-01	1990-11-29	Verbesserte methode zur herstellung von einem zwischenprodukt zur bereitung von bambuterol.
EP91900394A EP0456799B1 (en)	1989-12-01	1990-11-29	Improved method of preparing an intermediate for the manufacture of bambuterol
PT96051A PT96051B (pt)	1989-12-01	1990-11-30	Processo melhorado para a preparacao de 2'-bromo-3,5-di-{n-dimetilcarbamoiloxi}-acetofenona, composto intermedio utilizado na preparacao do bambuterol
NO912853A NO174804B (no)	1989-12-01	1991-07-19	Fremgangsmåte for fremstilling av et mellomprodukt for fremstilling av bambuterol

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
SE8904064A SE8904064D0 (sv)	1989-12-01	1989-12-01	Improved method of preparing an intermediate for the manufacture of bambuterol

Publications (1)

Publication Number	Publication Date
SE8904064D0 true SE8904064D0 (sv)	1989-12-01

Family

ID=20377664

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
SE8904064A SE8904064D0 (sv)	1989-12-01	1989-12-01	Improved method of preparing an intermediate for the manufacture of bambuterol

Country Status (14)

Country	Link
US (1)	US5200551A (da)
EP (1)	EP0456799B1 (da)
JP (1)	JPH04503218A (da)
AT (1)	ATE106388T1 (da)
AU (1)	AU630013B2 (da)
CA (1)	CA2045554A1 (da)
DE (1)	DE69009461T2 (da)
DK (1)	DK0456799T3 (da)
ES (1)	ES2054483T3 (da)
IE (1)	IE65994B1 (da)
NO (1)	NO174804B (da)
PT (1)	PT96051B (da)
SE (1)	SE8904064D0 (da)
WO (1)	WO1991008197A1 (da)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JP4954886B2 (ja) *	2004-11-08	2012-06-20	エムキュアファーマシューティカルズリミテッド	（ｓ）−３−［（１−ジメチルアミノ）エチル］−フェニル−ｎ−エチル−ｎ−メチル−カルバミン酸の効率的製造方法
ES2301439B1 (es) *	2005-08-31	2009-05-01	Universidad De Malaga	Uso de aminoacido tipo micosporina (m-gly) como antioxidante o aditivo en productos alimentarios.
KR100701743B1 (ko)	2005-10-05	2007-03-29	주식회사 라이트팜텍	밤부테롤의 신규한 제조 방법
CN102617404A (zh) *	2012-04-06	2012-08-01	张长利	盐酸班布特罗及其中间体的制备工艺
CN104262202B (zh) *	2014-09-12	2016-12-07	广东东阳光药业有限公司	班布特罗中间体的制备工艺
CN106187820B (zh) *	2016-07-02	2017-09-19	深圳市康立生生物科技有限公司	一种班布特罗杂质b的制备方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3404975A (en) *	1964-12-18	1968-10-08	Fmc Corp	m-(carbamoyloxy)-carbanilates as herbicides
DE3163871D1 (en) *	1980-07-09	1984-07-05	Draco Ab	1-(dihydroxyphenyl)-2-amino-ethanol derivatives; preparation, compositions and intermediates
DE3441108A1 (de) *	1984-11-10	1986-05-15	Basf Ag, 6700 Ludwigshafen	Verfahren zur herstellung von o-(1-methoxy-2-chlor)-ethoxyphenyl-n-methylcarbamat
US4925971A (en) *	1987-12-08	1990-05-15	Asahi Kasei Kogyo Kabushiki Kaisha	Method for producing aliphatic o-arylurethanes

1989
- 1989-12-01 SE SE8904064A patent/SE8904064D0/xx unknown
1990
- 1990-11-20 US US07/741,424 patent/US5200551A/en not_active Expired - Fee Related
- 1990-11-26 IE IE424790A patent/IE65994B1/en not_active IP Right Cessation
- 1990-11-29 WO PCT/SE1990/000792 patent/WO1991008197A1/en not_active Ceased
- 1990-11-29 AT AT91900394T patent/ATE106388T1/de not_active IP Right Cessation
- 1990-11-29 CA CA002045554A patent/CA2045554A1/en not_active Abandoned
- 1990-11-29 DK DK91900394.7T patent/DK0456799T3/da active
- 1990-11-29 EP EP91900394A patent/EP0456799B1/en not_active Expired - Lifetime
- 1990-11-29 ES ES91900394T patent/ES2054483T3/es not_active Expired - Lifetime
- 1990-11-29 JP JP3501014A patent/JPH04503218A/ja active Pending
- 1990-11-29 DE DE69009461T patent/DE69009461T2/de not_active Expired - Fee Related
- 1990-11-29 AU AU68981/91A patent/AU630013B2/en not_active Ceased
- 1990-11-30 PT PT96051A patent/PT96051B/pt not_active IP Right Cessation
1991
- 1991-07-19 NO NO912853A patent/NO174804B/no unknown

Also Published As

Publication number	Publication date
WO1991008197A1 (en)	1991-06-13
IE65994B1 (en)	1995-11-29
US5200551A (en)	1993-04-06
EP0456799B1 (en)	1994-06-01
AU6898191A (en)	1991-06-26
DK0456799T3 (da)	1994-10-03
NO912853D0 (no)	1991-07-19
NO174804B (no)	1994-04-05
PT96051B (pt)	1998-02-27
AU630013B2 (en)	1992-10-15
EP0456799A1 (en)	1991-11-21
IE904247A1 (en)	1991-06-05
DE69009461D1 (de)	1994-07-07
CA2045554A1 (en)	1991-06-02
PT96051A (pt)	1991-09-13
NO912853L (no)	1991-07-19
DE69009461T2 (de)	1994-10-13
NO174804C (da)	1994-07-13
JPH04503218A (ja)	1992-06-11
ES2054483T3 (es)	1994-08-01
ATE106388T1 (de)	1994-06-15

Publication	Publication Date	Title
Bleasdale	1952	Atmospheric pollution and plant growth
ES8604576A1 (es)	1986-02-01	Procedimiento para preparar derivados de benzodifuranona.
SE8904064D0 (sv)	1989-12-01	Improved method of preparing an intermediate for the manufacture of bambuterol
ES468324A1 (es)	1979-10-16	Procedimiento para la obtencion de una mezcla de compuestos polihidroxilicos de bajo peso molecular
PT85972A (de)	1987-11-01	Verfahren zum herstellen eines brausegranulates danach hergestelltes brausegranulat sowie dessen verwendung
JPS5562043A (en)	1980-05-10	Preparation of phenoxycarboxylic acid derivative
JPS5622751A (en)	1981-03-03	Preparation of nitrodiphenylamine
JPS5448798A (en)	1979-04-17	3-tetrazolyl-1-azaxanthone derivative and its preparation
JPS5592348A (en)	1980-07-12	Preparation of 1,17-diamino-9-azaheptadecane
JPS549247A (en)	1979-01-24	Preparation of menthone
JPS53108952A (en)	1978-09-22	Production of cyclohexylbenzenes
RO107650B1 (ro)	1993-12-30	Procedeu de obținere a clorurii de tetrametilamoniu și a clorurii de trietilmetilamoniu
JPS53144543A (en)	1978-12-15	Improved method of producing cylcohexane derivative
JPS5492942A (en)	1979-07-23	Production of 3-amino-2-cyclohexenone
JPS54145634A (en)	1979-11-14	Preparation of 2,6-dicyanophenol derivative
JPS53101317A (en)	1978-09-04	Preparation of nitoranilene
JPS5334765A (en)	1978-03-31	Isolation of 1,5-dinitroanthraquinone
CN119118946A (zh)	2024-12-13	一种安全高效制备[1,4,5]氧二氮杂庚烷的方法
JPS562975A (en)	1981-01-13	Preparation of 2-amino-4,6-dichloro-1,3,5-triazine
CN1072675A (zh)	1993-06-02	二苯甲酮衍生物的制备方法
JPS55153751A (en)	1980-11-29	Preparation of phenylenediamine
JPS5439073A (en)	1979-03-24	Preparation of 2,3,3-trimethylindolenine
JPS53124219A (en)	1978-10-30	Preparation of derivative of 5-oxocarboxylic acid
JPS5412350A (en)	1979-01-30	Preparation of trans-chrysanthemum-monocarboxylic acid chloride
JPS5223053A (en)	1977-02-21	Preparation of 4,4'-diaminostilbene- 2,2'-disulfonic acid and its salt s

SE8904064D0 - Improved method of preparing an intermediate for the manufacture of bambuterol - Google Patents

Info

Links

Classifications

Landscapes

Priority Applications (14)

Applications Claiming Priority (1)

Publications (1)

Family

ID=20377664

Family Applications (1)

Country Status (14)

Families Citing this family (6)

Family Cites Families (4)

Also Published As

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