SG125079A1 - Oxazolidinones to treat eye infections - Google Patents

Oxazolidinones to treat eye infections

Info

Publication number
SG125079A1
SG125079A1 SG200300091A SG200300091A SG125079A1 SG 125079 A1 SG125079 A1 SG 125079A1 SG 200300091 A SG200300091 A SG 200300091A SG 200300091 A SG200300091 A SG 200300091A SG 125079 A1 SG125079 A1 SG 125079A1
Authority
SG
Singapore
Prior art keywords
oxazolidinones
eye infections
treat eye
treat
oxazolidinone
Prior art date
Application number
SG200300091A
Other languages
English (en)
Inventor
Robert D Cochran
Charles W Ford
Original Assignee
Upjohn Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Upjohn Co filed Critical Upjohn Co
Publication of SG125079A1 publication Critical patent/SG125079A1/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/42Oxazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/53751,4-Oxazines, e.g. morpholine
    • A61K31/53771,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/42Oxazoles
    • A61K31/422Oxazoles not condensed and containing further heterocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/444Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring heteroatom, e.g. amrinone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/496Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/5355Non-condensed oxazines and containing further heterocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0048Eye, e.g. artificial tears

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Oncology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Communicable Diseases (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicinal Preparation (AREA)
SG200300091A 1998-07-14 1999-07-07 Oxazolidinones to treat eye infections SG125079A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US9276598P 1998-07-14 1998-07-14

Publications (1)

Publication Number Publication Date
SG125079A1 true SG125079A1 (en) 2006-09-29

Family

ID=22235050

Family Applications (1)

Application Number Title Priority Date Filing Date
SG200300091A SG125079A1 (en) 1998-07-14 1999-07-07 Oxazolidinones to treat eye infections

Country Status (27)

Country Link
US (2) US6337329B1 (fr)
EP (1) EP1096934B1 (fr)
JP (1) JP2002520359A (fr)
KR (1) KR20010079530A (fr)
CN (1) CN1305374A (fr)
AT (1) ATE304886T1 (fr)
AU (1) AU740781B2 (fr)
BG (1) BG64666B1 (fr)
BR (1) BR9912004A (fr)
CA (1) CA2334811A1 (fr)
DE (1) DE69927380T2 (fr)
DK (1) DK1096934T3 (fr)
EA (1) EA003274B1 (fr)
EE (1) EE200100026A (fr)
ES (1) ES2249020T3 (fr)
HU (1) HUP0102836A3 (fr)
ID (1) ID27276A (fr)
IL (1) IL140769A0 (fr)
NO (1) NO20010202L (fr)
NZ (1) NZ509375A (fr)
PL (1) PL345544A1 (fr)
PT (1) PT1096934E (fr)
SG (1) SG125079A1 (fr)
SK (1) SK20332000A3 (fr)
TR (1) TR200100066T2 (fr)
WO (1) WO2000003710A1 (fr)
ZA (1) ZA200100038B (fr)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR020660A1 (es) * 1998-09-30 2002-05-22 Alcon Lab Inc Composiciones antibioticas para el tratamiento de ojos, oidos y nariz
KR20020063851A (ko) * 1999-09-13 2002-08-05 인사이트 비젼 인코포레이티드 안구 감염 예방용 국소 치료제
GB9928568D0 (en) 1999-12-03 2000-02-02 Zeneca Ltd Chemical compounds
GB0009803D0 (en) 2000-04-25 2000-06-07 Astrazeneca Ab Chemical compounds
US6562820B2 (en) * 2000-07-05 2003-05-13 Pharmacia & Upjohn Company Method for treatment and prevention of mastitis
PE20020300A1 (es) * 2000-08-22 2002-05-10 Pharmacia Corp Composicion de solucion de un farmaco antibiotico a base de oxazolidinona con mejoramiento de la carga de farmaco
PE20020578A1 (es) * 2000-10-10 2002-08-14 Upjohn Co Una composicion de antibiotico topico para el tratamiento de infecciones oculares
US7125568B2 (en) 2001-08-23 2006-10-24 Sung Michael T Lipophilic drug compositions
US20030069235A1 (en) * 2001-09-14 2003-04-10 J. Greg Slatter Treatment for ocular infections
BR0307898A (pt) * 2002-02-22 2004-12-07 Pharmacia Corp Formulações de droga antibiótica oftálmica contendo um composto de ciclodextrina e cloreto de cetil piridìnio
TW201043267A (en) * 2009-03-19 2010-12-16 Intervet Int Bv In situ constituting a vaccine for administration to a predetermined herd of animals
CN101766628B (zh) * 2010-01-20 2012-07-04 广东宏盈科技有限公司 一种眼科外用抗细菌感染药物
JP6419701B2 (ja) * 2012-09-13 2018-11-07 スターファーマ・ピーティーワイ・リミテッド 眼の感染症の治療または予防方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5164510A (en) * 1988-09-15 1992-11-17 The Upjohn Company 5'Indolinyl-5β-amidomethyloxazolidin-2-ones
US5231188A (en) * 1989-11-17 1993-07-27 The Upjohn Company Tricyclic [6.5.51]-fused oxazolidinone antibacterial agents
EP0610265B1 (fr) 1991-11-01 1996-12-27 PHARMACIA & UPJOHN COMPANY Aryl- et heteroarylphenyloxazolidinones substituees, utilisees comme agents antibacteriens
US5688792A (en) 1994-08-16 1997-11-18 Pharmacia & Upjohn Company Substituted oxazine and thiazine oxazolidinone antimicrobials
CA2174107C (fr) * 1993-11-22 2005-04-12 Steven J. Brickner Esters de derives de substitution d'hydroxyacetyl-piperazinyl-phenyl-oxazolidinones
DE4425612A1 (de) * 1994-07-20 1996-04-04 Bayer Ag 6-gliedrige stickstoffhaltige Heteroaryl-oxazolidinone
DE4425613A1 (de) * 1994-07-20 1996-01-25 Bayer Ag 5-gliedrige Heteroaryl-oxazolidinone
EP0951295B1 (fr) 1996-05-31 2010-06-09 The Scripps Research Institute Compositions pour l'utilisation afin d'inhiber l'angiogenese mediee par alpha-v- beta3

Also Published As

Publication number Publication date
HUP0102836A2 (hu) 2002-05-29
EA003274B1 (ru) 2003-04-24
HUP0102836A3 (en) 2003-12-29
BR9912004A (pt) 2001-04-10
WO2000003710A1 (fr) 2000-01-27
PT1096934E (pt) 2005-11-30
ES2249020T3 (es) 2006-03-16
SK20332000A3 (sk) 2001-05-10
ATE304886T1 (de) 2005-10-15
TR200100066T2 (tr) 2001-05-21
JP2002520359A (ja) 2002-07-09
DE69927380D1 (de) 2005-10-27
AU740781B2 (en) 2001-11-15
KR20010079530A (ko) 2001-08-22
EA200100133A1 (ru) 2001-06-25
BG105142A (en) 2001-10-31
EP1096934A1 (fr) 2001-05-09
NZ509375A (en) 2003-11-28
PL345544A1 (en) 2001-12-17
DE69927380T2 (de) 2006-07-06
US6740652B2 (en) 2004-05-25
BG64666B1 (bg) 2005-11-30
NO20010202D0 (no) 2001-01-12
NO20010202L (no) 2001-01-12
ID27276A (id) 2001-03-22
IL140769A0 (en) 2002-02-10
CA2334811A1 (fr) 2000-01-27
EE200100026A (et) 2002-06-17
ZA200100038B (en) 2002-01-02
CN1305374A (zh) 2001-07-25
DK1096934T3 (da) 2005-11-28
EP1096934B1 (fr) 2005-09-21
US6337329B1 (en) 2002-01-08
AU4953099A (en) 2000-02-07
US20020065280A1 (en) 2002-05-30

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